Gene Symbol | lin-12 |
Entrez Gene ID | 176282 |
Full Name | Protein lin-12 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » lin-12 cDNA ORF clone
Gene Symbol | lin-12 |
Entrez Gene ID | 176282 |
Full Name | Protein lin-12 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_066606.3 | NP_499007.1 | Protein lin-12 |
NM_066606.4 | NP_499007.1 | Protein lin-12 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Molecular and genetic analyses indicate that the loss of ubr-5 function suppresses defects caused by reduced signaling via GLP-1 or LIN-12.
Title: UBR-5, a Conserved HECT-Type E3 Ubiquitin Ligase, Negatively Regulates Notch-Type Signaling in Caenorhabditis elegans.
These findings provide additional evidence highlighting the roles of LIN-12/Notch signaling in coordinating the formation of various components of the functional C. elegans egg-laying system.
Title: A role of the LIN-12/Notch signaling pathway in diversifying the non-striated egg-laying muscles in C. elegans.
Here we identify two cis-regulatory regions from lin-12, both of them are specified by the presence of a conserved EXD/HOX composite binding site. the two Notch paralogs in the C. elegans nervous system.
Title: Identification of novel cis-regulatory regions from the Notch receptor genes lin-12 and glp-1 of Caenorhabditis elegans.
LIN-12 signaling is necessary for the suppression of lag-1 expression in the anchor cell in Caenorhabditis elegans.
Title: LIN-12/Notch regulates lag-1 and lin-12 expression during anchor cell/ventral uterine precursor cell fate specification.
LIN-12/Notch signaling mediates type-2 vulval muscle cell development of muscle arms by regulating UNC-40 and MADD-2 activity.
Title: LIN-12/Notch signaling instructs postsynaptic muscle arm development by regulating UNC-40/DCC and MADD-2 in Caenorhabditis elegans.
The following lin-12 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the lin-12 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa341773 | |
Clone ID Related Accession (Same CDS sequence) | NM_066606.3 , NM_066606.4 | |
Accession Version | NM_066606.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 4290bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Protein lin-12 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Jun 26, 2012 this sequence version replaced NM_066606.2. COMPLETENESS: incomplete on both ends. |
1 | ATGCGGATCC CTACGATTTG TTTTTTATTT CTTCTTATCT CGTTATCAAA ATCGCTTCAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_499007.1 |
CDS | 1..4290 |
Translation |
Target ORF information:
Target ORF information:
|
NM_066606.3 |
1 | ATGCGGATCC CTACGATTTG TTTTTTATTT CTTCTTATCT CGTTATCAAA ATCGCTTCAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa341773 | |
Clone ID Related Accession (Same CDS sequence) | NM_066606.3 , NM_066606.4 | |
Accession Version | NM_066606.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 4290bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Protein lin-12 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Sep 4, 2019 this sequence version replaced NM_066606.3. |
1 | ATGCGGATCC CTACGATTTG TTTTTTATTT CTTCTTATCT CGTTATCAAA ATCGCTTCAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_499007.1 |
CDS | 373..4662 |
Translation |
Target ORF information:
Target ORF information:
|
NM_066606.4 |
1 | ATGCGGATCC CTACGATTTG TTTTTTATTT CTTCTTATCT CGTTATCAAA ATCGCTTCAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |