smc-6 cDNA ORF clone, Caenorhabditis elegans

Gene
Clones
gRNAs

Summary

Gene Symbol	smc-6
Entrez Gene ID	174776
Full Name	Structural maintenance of chromosomes protein 6 homolog smc-6
Gene Type	protein-coding
Organism	Caenorhabditis elegans

mRNA and Protein(s)

mRNA	Protein	Name
NM_064075.7	NP_496476.2	Structural maintenance of chromosomes protein 6 homolog smc-6
NM_064075.6	NP_496476.2	Structural maintenance of chromosomes protein 6 homolog smc-6

Pathways from BioSystems

Homologies

Caenorhabditis elegans (roundworm)	smc-6	NP_496476.2
Caenorhabditis elegans (roundworm)	C23H4.6	NP_001257190.1

Gene Ontology
Bibliography

Related articles in PubMed

Genome sequence of the nematode C. elegans: a platform for investigating biology.

Science (New York, N.Y.)282(5396)2012-8(1998 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Our results suggest that SMC-5/6 and HIM-6 can synergistically regulate recombination intermediate metabolism and suppress ectopic recombination by controlling chromosome architecture during meiosis.
Title: The SMC-5/6 Complex and the HIM-6 (BLM) Helicase Synergistically Promote Meiotic Recombination Intermediate Processing and Chromosome Maturation during Caenorhabditis elegans Meiosis.

Data propose that SMC-5/6 promotes replication fork stability and facilitates recombination-dependent repair.
Title: Loss of Caenorhabditis elegans BRCA1 promotes genome stability during replication in smc-5 mutants.

The following smc-6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the smc-6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OCa337695	NM_064075.7 Latest version!	Caenorhabditis elegans Structural maintenance of chromosomes protein 6 homolog smc-6 (smc-6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$559.30 $799.00
View Old Accession Versions >>
OCa337695	NM_064075.6	Caenorhabditis elegans Structural maintenance of chromosomes protein 6 homolog smc-6 (smc-6), partial mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$629.30 $899.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

smc-6 ( NM_064075.7 ) cDNA ORF clone, Caenorhabditis elegans -> NP_496476.2 Caenorhabditis elegans Structural maintenance of chromosomes protein 6 homolog smc-6 (smc-6), mRNA.

Price & Availability↑

CloneID	OCa337695
Clone ID Related Accession (Same CDS sequence)	NM_064075.7 , NM_064075.6
Accession Version	NM_064075.7 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3450bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-17
Organism	Caenorhabditis elegans
Product	Structural maintenance of chromosomes protein 6 homolog smc-6
Comment	Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003280). On Sep 4, 2019 this sequence version replaced NM_064075.6.

ATGGGTAAAC GGGACATCCC GAGTCCCAAC GAGAATATCG CACCCAGGAC AATAGGAATG 
CGAGATGTCG ACCTCACTGC AGCGCCTGCG AAAAAAGCGA AATTGGATAC CGGAGAGAGA 
ATCGCCGTTT CTGGACGTGT TGCTTCAGTA AAACTTACCA ACTTCATGTG CCACGCAAAT 
CTTCAAATCG ATTTCAAAAC GGCACAAAAC AATTGCTTTT ATATCGGTGG CCCGAATGGA 
AGTGGAAAGA GTGCTCTGTT CGCTGCAATC AATTTGGGTC TTGGAGGACG AGGTTCTGAT 
AATGATCGAG GAAACACGGT GAAGTCTTAC ATCAAAGATG GAACAACACA ATCCAAAATC 
ACGATCACAC TGACCAATGC AGGATTGAAC GCTCATCCAG ATTTCGATGA TCTCATTTCC 
ATTGAGAGAA CGATCAATCA GGCATCGTCA ACCTATATTA TGAAAAGTGT AAAAGTGACA 
TCCTCCGATA ATCACGTTGA GCGAATTGTG AGCAGGAAAA AGGCCGACGT CGATCGCATT 
GTGAGCCGAT TCAGCATTCA TCTCTCGAAT CCTGCATTTT GGATGAGTCA AGACAGATCA 
CGAAGTTTTC TTGCAAACTT CAAACCAGCA AATGTCTACA AGCTGTATCT TGAATCTACG 
AATCTTGAGA ACATCCGATT ATCTTATATC CGATTTGCCG ACGCTTTGGA TGAATGCTTC 
GCGTTGATAC AGCTGAAGGC TGGAGAAATT TTGAACGAGC AGAAAAAGCT GAAGCGAATG 
CAAGAACAAC GTGATCTCCA AGCGAAGCTA GACCAGGATC GTGCACTTGT TGCCAGTTTT 
TGCTGGAAGC TTCTCTTCTG TAAAGTTCGC GATTACAACG ATCAAATCGA ACTGACTCTT 
AAGAAGCAGG AAGCTCAGAA AACCTTACAA GATGAAACCA AAAAGGAATA CGCTAAAAAT 
CGTGCTGCCA GAACAGAAGT TGAGAAGAAA ATTCAAGAGT TTAGAGACGA GGTCGAAGTT 
CAGGATGCGG AAATAGCTGA AGCAAGAGAG GATTTAGATG CGAAGAAAAG AAAAGTTCTC 
GAATTCGAAG AGAAGATTCG AGAGTGTGAA CAGAGTATTA GGAAAAAGAC ATCCGAGAAG 
AAATACATGG AACGGACGAT CGTTAATGCT AAAAATGAAG TTCGCATTCT TCTTGAAAAG 
CAGGGAAATC AGGATTTGAC AAAGAGGCTG ACCAAAGTTG AGAACGATTA TAAGGATATC 
TCTCAACAAA GAGAGAACAT GGAGTTAGGA GGCGAATCAG CAAAGCTGAG GGAAAAACTT 
GACACGGTGA TTACTGACTA CAAAAGGAAA GAAGAAGAAA AGTATACAAT ACAAAGAGAT 
ATAAATCAAC TTCGTCGGAA AATTGAACAG GATATGGAGA CAATGCGACG GTCCAGAGCC 
ACCAAGAAAG ACGCCATCAA CAAATTCGGC TCACACATGG CTGAAATACT CATGGAAATC 
AACCGAAGCA AGTCCCGATT CCAAACTGTT CCAAAAGGTC CTCTTGGAAA GTACATCACG 
TTGATCGATC CAAAATGGGC ATTCACTGTT GAAGAATGTA TTGGAAATCT TGCAAACAAC 
TTCTTGTGTT CCAGTCATCT AGATGCAGAG ATCCTCCGAA ACATCTTCCA AAGCCTTCGA 
ATTCCAGCAC AAGACCGGCC GACGATTATT GTAGCCAAGT GCAATGGAAG AGCTTATACC 
AATCTTCATG AGCCAAGCTC AGACTTTAAA AGTATCTACC GGGTGCTCAA GTTTTCAGAT 
CCAGATGTTC ATAACGTGAT CATCGACAAG AGCAACTGTG AACAGTTCAT TTTGATCGAA 
GACAAAACTG AAGCCATGGA GCTCATGGGA AGCAATTATC CACCTCAAAA TGCAGTCAAA 
GCGTACACAC TGGATGGATC TCAAGCATAT GCTAATGGAC CAAATAGTCA GTATCGTTTC 
TACAGTGGTA GAGGAGGACA TGCACGTGGT ACTTTTGGAA ATGATCAGGG AGATGTTGAT 
GAAGGAGCAT TAGCCAGACT GATTGAAGAT ACTAAATCGG AAGCCATGAG ACTGGAAACT 
CAAGATTTGC GAAAACAAGA TCATGAGCTG AAAGTGATAT ATAATGAGCG TGATCAGACG 
AAAGCTGCAA TTGATGAATT CGATAGAAAA TTGTCAAATC TTCGATCTCA AGAATTGCAG 
AAAGAACGTC AGGCAAAAGA TTTGAGAGCA GAATTGGCGC AAACTGCGAA TGAAGATCAA 
GTGGAAAATC TGAATGAATC TATTGAGGAA ATGCAGAAAA AGATTCCTTT AATCGAGGAT 
GAAGTCAAAG ATATTCTGAA AAATGTGGCA GACATCACTG CAGACATGGC TCCAGTTATT 
CAAGAGAGGA AAGAAGCGGA ACATACGCTA GCGGAAATTC AAAAAGAAAC ACGAGATTTT 
GCAAGTAAAT CCCAGAAACT TCAAAACGAA TTGAGCAAGT ATGACGACGC CGGAGAGATT 
CTCAAAATTC GTCTCGATAA AGTGAAAGCT GACGAAGGTG TATTCTTCCA CACAGAGGCG 
AAACTCAAAT CTGAAAGAGA CGATGCGATG GAAATGGTGG AAAACGACAA AAAGAATCAT 
CCAATGCCAC CTGGCGAGAC AGATCCACCA GATCTTTCAA GTTTCCCGTC GACGACTGAA 
GCTCAGAGAA AGATCGAAGA AATGCAGAAA GCAGTTGACA GAGCAACAGT TGGATGTGAC 
ACTACTATTA CTCTTGAATG TGTTAAAGAC TTTAAAGATA AACTGAAAAG GTTGAAGTAT 
CTGTGTCGCA TGATTGAAGA TGTTCTCATC GAGCTTAAAA ATCTTCATGC AGCCCGTGTA 
AAAGCATATC CGAGCTTGAA AAAGTTCACG GAATTGAAGG TGTGTAACAA GTTCCAGGAG 
TTGCTCGCAG TTCGAGGTCA TTTTATCGGT GGTCTCGAAT TCGATCACGA GAAGGAGACA 
CTTAATGTGA ATGTTCAATC TTCTAAAGAG AAGGATGCGA TGGCTGGACG AAGACCTGAA 
GTCCTTGAGG TAGAAGAAGT CGACGAGCAT TCGTATGATG ATGATAGTGA CGATAGTACC 
GGTCCGCGTA GAAAGAAGTC CAAGAAGAGC GGCCAGAAAA AGAAGAGAGT TCGTGATCTG 
AAAGGATTAT CCGGAGGAGA ACGGTCTTTT GTGACTGCCG CACTCGTCAT GTCCTTGTGG 
GAAGTTATGG AGCAGCCATT CCGAATGATG GATGAGTTTG ATGTCTTTAT GGACATGATG 
AATAGAAAGC TGGTGATGGA TTTGCTCGTC GAGCTGGCCA CCAAGAAGTT CCCTCACAAT 
CAGTTCATCT TCTTCACTCC ACAAGGAATC AAGGAACTCA ACATGGTCGA TGGTCTTCAA 
GTTTTCGAGA TGAACAGAGT CCGCGACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_496476.2
CDS	5..3454
Translation	MGKRDIPSPNENIAPRTIGMRDVDLTAAPAKKAKLDTGERIAVSGRVASVKLTNFMCHANLQIDFKTAQNNCFYIGGPNGSGKSALFAAINLGLGGRGSDNDRGNTVKSYIKDGTTQSKITITLTNAGLNAHPDFDDLISIERTINQASSTYIMKSVKVTSSDNHVERIVSRKKADVDRIVSRFSIHLSNPAFWMSQDRSRSFLANFKPANVYKLYLESTNLENIRLSYIRFADALDECFALIQLKAGEILNEQKKLKRMQEQRDLQAKLDQDRALVASFCWKLLFCKVRDYNDQIELTLKKQEAQKTLQDETKKEYAKNRAARTEVEKKIQEFRDEVEVQDAEIAEAREDLDAKKRKVLEFEEKIRECEQSIRKKTSEKKYMERTIVNAKNEVRILLEKQGNQDLTKRLTKVENDYKDISQQRENMELGGESAKLREKLDTVITDYKRKEEEKYTIQRDINQLRRKIEQDMETMRRSRATKKDAINKFGSHMAEILMEINRSKSRFQTVPKGPLGKYITLIDPKWAFTVEECIGNLANNFLCSSHLDAEILRNIFQSLRIPAQDRPTIIVAKCNGRAYTNLHEPSSDFKSIYRVLKFSDPDVHNVIIDKSNCEQFILIEDKTEAMELMGSNYPPQNAVKAYTLDGSQAYANGPNSQYRFYSGRGGHARGTFGNDQGDVDEGALARLIEDTKSEAMRLETQDLRKQDHELKVIYNERDQTKAAIDEFDRKLSNLRSQELQKERQAKDLRAELAQTANEDQVENLNESIEEMQKKIPLIEDEVKDILKNVADITADMAPVIQERKEAEHTLAEIQKETRDFASKSQKLQNELSKYDDAGEILKIRLDKVKADEGVFFHTEAKLKSERDDAMEMVENDKKNHPMPPGETDPPDLSSFPSTTEAQRKIEEMQKAVDRATVGCDTTITLECVKDFKDKLKRLKYLCRMIEDVLIELKNLHAARVKAYPSLKKFTELKVCNKFQELLAVRGHFIGGLEFDHEKETLNVNVQSSKEKDAMAGRRPEVLEVEEVDEHSYDDDSDDSTGPRRKKSKKSGQKKKRVRDLKGLSGGERSFVTAALVMSLWEVMEQPFRMMDEFDVFMDMMNRKLVMDLLVELATKKFPHNQFIFFTPQGIKELNMVDGLQVFEMNRVRD

Target ORF information:

RefSeq Version	NM_064075.7
Organism	Caenorhabditis elegans
Definition	Caenorhabditis elegans Structural maintenance of chromosomes protein 6 homolog smc-6 (smc-6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_064075.7

ORF Insert Sequence:

ATGGGTAAAC GGGACATCCC GAGTCCCAAC GAGAATATCG CACCCAGGAC AATAGGAATG 
CGAGATGTCG ACCTCACTGC AGCGCCTGCG AAAAAAGCGA AATTGGATAC CGGAGAGAGA 
ATCGCCGTTT CTGGACGTGT TGCTTCAGTA AAACTTACCA ACTTCATGTG CCACGCAAAT 
CTTCAAATCG ATTTCAAAAC GGCACAAAAC AATTGCTTTT ATATCGGTGG CCCGAATGGA 
AGTGGAAAGA GTGCTCTGTT CGCTGCAATC AATTTGGGTC TTGGAGGACG AGGTTCTGAT 
AATGATCGAG GAAACACGGT GAAGTCTTAC ATCAAAGATG GAACAACACA ATCCAAAATC 
ACGATCACAC TGACCAATGC AGGATTGAAC GCTCATCCAG ATTTCGATGA TCTCATTTCC 
ATTGAGAGAA CGATCAATCA GGCATCGTCA ACCTATATTA TGAAAAGTGT AAAAGTGACA 
TCCTCCGATA ATCACGTTGA GCGAATTGTG AGCAGGAAAA AGGCCGACGT CGATCGCATT 
GTGAGCCGAT TCAGCATTCA TCTCTCGAAT CCTGCATTTT GGATGAGTCA AGACAGATCA 
CGAAGTTTTC TTGCAAACTT CAAACCAGCA AATGTCTACA AGCTGTATCT TGAATCTACG 
AATCTTGAGA ACATCCGATT ATCTTATATC CGATTTGCCG ACGCTTTGGA TGAATGCTTC 
GCGTTGATAC AGCTGAAGGC TGGAGAAATT TTGAACGAGC AGAAAAAGCT GAAGCGAATG 
CAAGAACAAC GTGATCTCCA AGCGAAGCTA GACCAGGATC GTGCACTTGT TGCCAGTTTT 
TGCTGGAAGC TTCTCTTCTG TAAAGTTCGC GATTACAACG ATCAAATCGA ACTGACTCTT 
AAGAAGCAGG AAGCTCAGAA AACCTTACAA GATGAAACCA AAAAGGAATA CGCTAAAAAT 
CGTGCTGCCA GAACAGAAGT TGAGAAGAAA ATTCAAGAGT TTAGAGACGA GGTCGAAGTT 
CAGGATGCGG AAATAGCTGA AGCAAGAGAG GATTTAGATG CGAAGAAAAG AAAAGTTCTC 
GAATTCGAAG AGAAGATTCG AGAGTGTGAA CAGAGTATTA GGAAAAAGAC ATCCGAGAAG 
AAATACATGG AACGGACGAT CGTTAATGCT AAAAATGAAG TTCGCATTCT TCTTGAAAAG 
CAGGGAAATC AGGATTTGAC AAAGAGGCTG ACCAAAGTTG AGAACGATTA TAAGGATATC 
TCTCAACAAA GAGAGAACAT GGAGTTAGGA GGCGAATCAG CAAAGCTGAG GGAAAAACTT 
GACACGGTGA TTACTGACTA CAAAAGGAAA GAAGAAGAAA AGTATACAAT ACAAAGAGAT 
ATAAATCAAC TTCGTCGGAA AATTGAACAG GATATGGAGA CAATGCGACG GTCCAGAGCC 
ACCAAGAAAG ACGCCATCAA CAAATTCGGC TCACACATGG CTGAAATACT CATGGAAATC 
AACCGAAGCA AGTCCCGATT CCAAACTGTT CCAAAAGGTC CTCTTGGAAA GTACATCACG 
TTGATCGATC CAAAATGGGC ATTCACTGTT GAAGAATGTA TTGGAAATCT TGCAAACAAC 
TTCTTGTGTT CCAGTCATCT AGATGCAGAG ATCCTCCGAA ACATCTTCCA AAGCCTTCGA 
ATTCCAGCAC AAGACCGGCC GACGATTATT GTAGCCAAGT GCAATGGAAG AGCTTATACC 
AATCTTCATG AGCCAAGCTC AGACTTTAAA AGTATCTACC GGGTGCTCAA GTTTTCAGAT 
CCAGATGTTC ATAACGTGAT CATCGACAAG AGCAACTGTG AACAGTTCAT TTTGATCGAA 
GACAAAACTG AAGCCATGGA GCTCATGGGA AGCAATTATC CACCTCAAAA TGCAGTCAAA 
GCGTACACAC TGGATGGATC TCAAGCATAT GCTAATGGAC CAAATAGTCA GTATCGTTTC 
TACAGTGGTA GAGGAGGACA TGCACGTGGT ACTTTTGGAA ATGATCAGGG AGATGTTGAT 
GAAGGAGCAT TAGCCAGACT GATTGAAGAT ACTAAATCGG AAGCCATGAG ACTGGAAACT 
CAAGATTTGC GAAAACAAGA TCATGAGCTG AAAGTGATAT ATAATGAGCG TGATCAGACG 
AAAGCTGCAA TTGATGAATT CGATAGAAAA TTGTCAAATC TTCGATCTCA AGAATTGCAG 
AAAGAACGTC AGGCAAAAGA TTTGAGAGCA GAATTGGCGC AAACTGCGAA TGAAGATCAA 
GTGGAAAATC TGAATGAATC TATTGAGGAA ATGCAGAAAA AGATTCCTTT AATCGAGGAT 
GAAGTCAAAG ATATTCTGAA AAATGTGGCA GACATCACTG CAGACATGGC TCCAGTTATT 
CAAGAGAGGA AAGAAGCGGA ACATACGCTA GCGGAAATTC AAAAAGAAAC ACGAGATTTT 
GCAAGTAAAT CCCAGAAACT TCAAAACGAA TTGAGCAAGT ATGACGACGC CGGAGAGATT 
CTCAAAATTC GTCTCGATAA AGTGAAAGCT GACGAAGGTG TATTCTTCCA CACAGAGGCG 
AAACTCAAAT CTGAAAGAGA CGATGCGATG GAAATGGTGG AAAACGACAA AAAGAATCAT 
CCAATGCCAC CTGGCGAGAC AGATCCACCA GATCTTTCAA GTTTCCCGTC GACGACTGAA 
GCTCAGAGAA AGATCGAAGA AATGCAGAAA GCAGTTGACA GAGCAACAGT TGGATGTGAC 
ACTACTATTA CTCTTGAATG TGTTAAAGAC TTTAAAGATA AACTGAAAAG GTTGAAGTAT 
CTGTGTCGCA TGATTGAAGA TGTTCTCATC GAGCTTAAAA ATCTTCATGC AGCCCGTGTA 
AAAGCATATC CGAGCTTGAA AAAGTTCACG GAATTGAAGG TGTGTAACAA GTTCCAGGAG 
TTGCTCGCAG TTCGAGGTCA TTTTATCGGT GGTCTCGAAT TCGATCACGA GAAGGAGACA 
CTTAATGTGA ATGTTCAATC TTCTAAAGAG AAGGATGCGA TGGCTGGACG AAGACCTGAA 
GTCCTTGAGG TAGAAGAAGT CGACGAGCAT TCGTATGATG ATGATAGTGA CGATAGTACC 
GGTCCGCGTA GAAAGAAGTC CAAGAAGAGC GGCCAGAAAA AGAAGAGAGT TCGTGATCTG 
AAAGGATTAT CCGGAGGAGA ACGGTCTTTT GTGACTGCCG CACTCGTCAT GTCCTTGTGG 
GAAGTTATGG AGCAGCCATT CCGAATGATG GATGAGTTTG ATGTCTTTAT GGACATGATG 
AATAGAAAGC TGGTGATGGA TTTGCTCGTC GAGCTGGCCA CCAAGAAGTT CCCTCACAAT 
CAGTTCATCT TCTTCACTCC ACAAGGAATC AAGGAACTCA ACATGGTCGA TGGTCTTCAA 
GTTTTCGAGA TGAACAGAGT CCGCGACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

smc-6 ( NM_064075.6 ) cDNA ORF clone, Caenorhabditis elegans -> NP_496476.2 Caenorhabditis elegans Structural maintenance of chromosomes protein 6 homolog smc-6 (smc-6), partial mRNA.

Price & Availability↑

CloneID	OCa337695
Clone ID Related Accession (Same CDS sequence)	NM_064075.7 , NM_064075.6
Accession Version	NM_064075.6	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3450bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-08
Organism	Caenorhabditis elegans
Product	Structural maintenance of chromosomes protein 6 homolog smc-6
Comment	Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003280). On Jun 26, 2012 this sequence version replaced NM_064075.5. COMPLETENESS: incomplete on both ends.

ATGGGTAAAC GGGACATCCC GAGTCCCAAC GAGAATATCG CACCCAGGAC AATAGGAATG 
CGAGATGTCG ACCTCACTGC AGCGCCTGCG AAAAAAGCGA AATTGGATAC CGGAGAGAGA 
ATCGCCGTTT CTGGACGTGT TGCTTCAGTA AAACTTACCA ACTTCATGTG CCACGCAAAT 
CTTCAAATCG ATTTCAAAAC GGCACAAAAC AATTGCTTTT ATATCGGTGG CCCGAATGGA 
AGTGGAAAGA GTGCTCTGTT CGCTGCAATC AATTTGGGTC TTGGAGGACG AGGTTCTGAT 
AATGATCGAG GAAACACGGT GAAGTCTTAC ATCAAAGATG GAACAACACA ATCCAAAATC 
ACGATCACAC TGACCAATGC AGGATTGAAC GCTCATCCAG ATTTCGATGA TCTCATTTCC 
ATTGAGAGAA CGATCAATCA GGCATCGTCA ACCTATATTA TGAAAAGTGT AAAAGTGACA 
TCCTCCGATA ATCACGTTGA GCGAATTGTG AGCAGGAAAA AGGCCGACGT CGATCGCATT 
GTGAGCCGAT TCAGCATTCA TCTCTCGAAT CCTGCATTTT GGATGAGTCA AGACAGATCA 
CGAAGTTTTC TTGCAAACTT CAAACCAGCA AATGTCTACA AGCTGTATCT TGAATCTACG 
AATCTTGAGA ACATCCGATT ATCTTATATC CGATTTGCCG ACGCTTTGGA TGAATGCTTC 
GCGTTGATAC AGCTGAAGGC TGGAGAAATT TTGAACGAGC AGAAAAAGCT GAAGCGAATG 
CAAGAACAAC GTGATCTCCA AGCGAAGCTA GACCAGGATC GTGCACTTGT TGCCAGTTTT 
TGCTGGAAGC TTCTCTTCTG TAAAGTTCGC GATTACAACG ATCAAATCGA ACTGACTCTT 
AAGAAGCAGG AAGCTCAGAA AACCTTACAA GATGAAACCA AAAAGGAATA CGCTAAAAAT 
CGTGCTGCCA GAACAGAAGT TGAGAAGAAA ATTCAAGAGT TTAGAGACGA GGTCGAAGTT 
CAGGATGCGG AAATAGCTGA AGCAAGAGAG GATTTAGATG CGAAGAAAAG AAAAGTTCTC 
GAATTCGAAG AGAAGATTCG AGAGTGTGAA CAGAGTATTA GGAAAAAGAC ATCCGAGAAG 
AAATACATGG AACGGACGAT CGTTAATGCT AAAAATGAAG TTCGCATTCT TCTTGAAAAG 
CAGGGAAATC AGGATTTGAC AAAGAGGCTG ACCAAAGTTG AGAACGATTA TAAGGATATC 
TCTCAACAAA GAGAGAACAT GGAGTTAGGA GGCGAATCAG CAAAGCTGAG GGAAAAACTT 
GACACGGTGA TTACTGACTA CAAAAGGAAA GAAGAAGAAA AGTATACAAT ACAAAGAGAT 
ATAAATCAAC TTCGTCGGAA AATTGAACAG GATATGGAGA CAATGCGACG GTCCAGAGCC 
ACCAAGAAAG ACGCCATCAA CAAATTCGGC TCACACATGG CTGAAATACT CATGGAAATC 
AACCGAAGCA AGTCCCGATT CCAAACTGTT CCAAAAGGTC CTCTTGGAAA GTACATCACG 
TTGATCGATC CAAAATGGGC ATTCACTGTT GAAGAATGTA TTGGAAATCT TGCAAACAAC 
TTCTTGTGTT CCAGTCATCT AGATGCAGAG ATCCTCCGAA ACATCTTCCA AAGCCTTCGA 
ATTCCAGCAC AAGACCGGCC GACGATTATT GTAGCCAAGT GCAATGGAAG AGCTTATACC 
AATCTTCATG AGCCAAGCTC AGACTTTAAA AGTATCTACC GGGTGCTCAA GTTTTCAGAT 
CCAGATGTTC ATAACGTGAT CATCGACAAG AGCAACTGTG AACAGTTCAT TTTGATCGAA 
GACAAAACTG AAGCCATGGA GCTCATGGGA AGCAATTATC CACCTCAAAA TGCAGTCAAA 
GCGTACACAC TGGATGGATC TCAAGCATAT GCTAATGGAC CAAATAGTCA GTATCGTTTC 
TACAGTGGTA GAGGAGGACA TGCACGTGGT ACTTTTGGAA ATGATCAGGG AGATGTTGAT 
GAAGGAGCAT TAGCCAGACT GATTGAAGAT ACTAAATCGG AAGCCATGAG ACTGGAAACT 
CAAGATTTGC GAAAACAAGA TCATGAGCTG AAAGTGATAT ATAATGAGCG TGATCAGACG 
AAAGCTGCAA TTGATGAATT CGATAGAAAA TTGTCAAATC TTCGATCTCA AGAATTGCAG 
AAAGAACGTC AGGCAAAAGA TTTGAGAGCA GAATTGGCGC AAACTGCGAA TGAAGATCAA 
GTGGAAAATC TGAATGAATC TATTGAGGAA ATGCAGAAAA AGATTCCTTT AATCGAGGAT 
GAAGTCAAAG ATATTCTGAA AAATGTGGCA GACATCACTG CAGACATGGC TCCAGTTATT 
CAAGAGAGGA AAGAAGCGGA ACATACGCTA GCGGAAATTC AAAAAGAAAC ACGAGATTTT 
GCAAGTAAAT CCCAGAAACT TCAAAACGAA TTGAGCAAGT ATGACGACGC CGGAGAGATT 
CTCAAAATTC GTCTCGATAA AGTGAAAGCT GACGAAGGTG TATTCTTCCA CACAGAGGCG 
AAACTCAAAT CTGAAAGAGA CGATGCGATG GAAATGGTGG AAAACGACAA AAAGAATCAT 
CCAATGCCAC CTGGCGAGAC AGATCCACCA GATCTTTCAA GTTTCCCGTC GACGACTGAA 
GCTCAGAGAA AGATCGAAGA AATGCAGAAA GCAGTTGACA GAGCAACAGT TGGATGTGAC 
ACTACTATTA CTCTTGAATG TGTTAAAGAC TTTAAAGATA AACTGAAAAG GTTGAAGTAT 
CTGTGTCGCA TGATTGAAGA TGTTCTCATC GAGCTTAAAA ATCTTCATGC AGCCCGTGTA 
AAAGCATATC CGAGCTTGAA AAAGTTCACG GAATTGAAGG TGTGTAACAA GTTCCAGGAG 
TTGCTCGCAG TTCGAGGTCA TTTTATCGGT GGTCTCGAAT TCGATCACGA GAAGGAGACA 
CTTAATGTGA ATGTTCAATC TTCTAAAGAG AAGGATGCGA TGGCTGGACG AAGACCTGAA 
GTCCTTGAGG TAGAAGAAGT CGACGAGCAT TCGTATGATG ATGATAGTGA CGATAGTACC 
GGTCCGCGTA GAAAGAAGTC CAAGAAGAGC GGCCAGAAAA AGAAGAGAGT TCGTGATCTG 
AAAGGATTAT CCGGAGGAGA ACGGTCTTTT GTGACTGCCG CACTCGTCAT GTCCTTGTGG 
GAAGTTATGG AGCAGCCATT CCGAATGATG GATGAGTTTG ATGTCTTTAT GGACATGATG 
AATAGAAAGC TGGTGATGGA TTTGCTCGTC GAGCTGGCCA CCAAGAAGTT CCCTCACAAT 
CAGTTCATCT TCTTCACTCC ACAAGGAATC AAGGAACTCA ACATGGTCGA TGGTCTTCAA 
GTTTTCGAGA TGAACAGAGT CCGCGACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_496476.2
CDS	1..3450
Translation	MGKRDIPSPNENIAPRTIGMRDVDLTAAPAKKAKLDTGERIAVSGRVASVKLTNFMCHANLQIDFKTAQNNCFYIGGPNGSGKSALFAAINLGLGGRGSDNDRGNTVKSYIKDGTTQSKITITLTNAGLNAHPDFDDLISIERTINQASSTYIMKSVKVTSSDNHVERIVSRKKADVDRIVSRFSIHLSNPAFWMSQDRSRSFLANFKPANVYKLYLESTNLENIRLSYIRFADALDECFALIQLKAGEILNEQKKLKRMQEQRDLQAKLDQDRALVASFCWKLLFCKVRDYNDQIELTLKKQEAQKTLQDETKKEYAKNRAARTEVEKKIQEFRDEVEVQDAEIAEAREDLDAKKRKVLEFEEKIRECEQSIRKKTSEKKYMERTIVNAKNEVRILLEKQGNQDLTKRLTKVENDYKDISQQRENMELGGESAKLREKLDTVITDYKRKEEEKYTIQRDINQLRRKIEQDMETMRRSRATKKDAINKFGSHMAEILMEINRSKSRFQTVPKGPLGKYITLIDPKWAFTVEECIGNLANNFLCSSHLDAEILRNIFQSLRIPAQDRPTIIVAKCNGRAYTNLHEPSSDFKSIYRVLKFSDPDVHNVIIDKSNCEQFILIEDKTEAMELMGSNYPPQNAVKAYTLDGSQAYANGPNSQYRFYSGRGGHARGTFGNDQGDVDEGALARLIEDTKSEAMRLETQDLRKQDHELKVIYNERDQTKAAIDEFDRKLSNLRSQELQKERQAKDLRAELAQTANEDQVENLNESIEEMQKKIPLIEDEVKDILKNVADITADMAPVIQERKEAEHTLAEIQKETRDFASKSQKLQNELSKYDDAGEILKIRLDKVKADEGVFFHTEAKLKSERDDAMEMVENDKKNHPMPPGETDPPDLSSFPSTTEAQRKIEEMQKAVDRATVGCDTTITLECVKDFKDKLKRLKYLCRMIEDVLIELKNLHAARVKAYPSLKKFTELKVCNKFQELLAVRGHFIGGLEFDHEKETLNVNVQSSKEKDAMAGRRPEVLEVEEVDEHSYDDDSDDSTGPRRKKSKKSGQKKKRVRDLKGLSGGERSFVTAALVMSLWEVMEQPFRMMDEFDVFMDMMNRKLVMDLLVELATKKFPHNQFIFFTPQGIKELNMVDGLQVFEMNRVRD

Target ORF information:

RefSeq Version	NM_064075.6
Organism	Caenorhabditis elegans
Definition	Caenorhabditis elegans Structural maintenance of chromosomes protein 6 homolog smc-6 (smc-6), partial mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_064075.6

ORF Insert Sequence:

ATGGGTAAAC GGGACATCCC GAGTCCCAAC GAGAATATCG CACCCAGGAC AATAGGAATG 
CGAGATGTCG ACCTCACTGC AGCGCCTGCG AAAAAAGCGA AATTGGATAC CGGAGAGAGA 
ATCGCCGTTT CTGGACGTGT TGCTTCAGTA AAACTTACCA ACTTCATGTG CCACGCAAAT 
CTTCAAATCG ATTTCAAAAC GGCACAAAAC AATTGCTTTT ATATCGGTGG CCCGAATGGA 
AGTGGAAAGA GTGCTCTGTT CGCTGCAATC AATTTGGGTC TTGGAGGACG AGGTTCTGAT 
AATGATCGAG GAAACACGGT GAAGTCTTAC ATCAAAGATG GAACAACACA ATCCAAAATC 
ACGATCACAC TGACCAATGC AGGATTGAAC GCTCATCCAG ATTTCGATGA TCTCATTTCC 
ATTGAGAGAA CGATCAATCA GGCATCGTCA ACCTATATTA TGAAAAGTGT AAAAGTGACA 
TCCTCCGATA ATCACGTTGA GCGAATTGTG AGCAGGAAAA AGGCCGACGT CGATCGCATT 
GTGAGCCGAT TCAGCATTCA TCTCTCGAAT CCTGCATTTT GGATGAGTCA AGACAGATCA 
CGAAGTTTTC TTGCAAACTT CAAACCAGCA AATGTCTACA AGCTGTATCT TGAATCTACG 
AATCTTGAGA ACATCCGATT ATCTTATATC CGATTTGCCG ACGCTTTGGA TGAATGCTTC 
GCGTTGATAC AGCTGAAGGC TGGAGAAATT TTGAACGAGC AGAAAAAGCT GAAGCGAATG 
CAAGAACAAC GTGATCTCCA AGCGAAGCTA GACCAGGATC GTGCACTTGT TGCCAGTTTT 
TGCTGGAAGC TTCTCTTCTG TAAAGTTCGC GATTACAACG ATCAAATCGA ACTGACTCTT 
AAGAAGCAGG AAGCTCAGAA AACCTTACAA GATGAAACCA AAAAGGAATA CGCTAAAAAT 
CGTGCTGCCA GAACAGAAGT TGAGAAGAAA ATTCAAGAGT TTAGAGACGA GGTCGAAGTT 
CAGGATGCGG AAATAGCTGA AGCAAGAGAG GATTTAGATG CGAAGAAAAG AAAAGTTCTC 
GAATTCGAAG AGAAGATTCG AGAGTGTGAA CAGAGTATTA GGAAAAAGAC ATCCGAGAAG 
AAATACATGG AACGGACGAT CGTTAATGCT AAAAATGAAG TTCGCATTCT TCTTGAAAAG 
CAGGGAAATC AGGATTTGAC AAAGAGGCTG ACCAAAGTTG AGAACGATTA TAAGGATATC 
TCTCAACAAA GAGAGAACAT GGAGTTAGGA GGCGAATCAG CAAAGCTGAG GGAAAAACTT 
GACACGGTGA TTACTGACTA CAAAAGGAAA GAAGAAGAAA AGTATACAAT ACAAAGAGAT 
ATAAATCAAC TTCGTCGGAA AATTGAACAG GATATGGAGA CAATGCGACG GTCCAGAGCC 
ACCAAGAAAG ACGCCATCAA CAAATTCGGC TCACACATGG CTGAAATACT CATGGAAATC 
AACCGAAGCA AGTCCCGATT CCAAACTGTT CCAAAAGGTC CTCTTGGAAA GTACATCACG 
TTGATCGATC CAAAATGGGC ATTCACTGTT GAAGAATGTA TTGGAAATCT TGCAAACAAC 
TTCTTGTGTT CCAGTCATCT AGATGCAGAG ATCCTCCGAA ACATCTTCCA AAGCCTTCGA 
ATTCCAGCAC AAGACCGGCC GACGATTATT GTAGCCAAGT GCAATGGAAG AGCTTATACC 
AATCTTCATG AGCCAAGCTC AGACTTTAAA AGTATCTACC GGGTGCTCAA GTTTTCAGAT 
CCAGATGTTC ATAACGTGAT CATCGACAAG AGCAACTGTG AACAGTTCAT TTTGATCGAA 
GACAAAACTG AAGCCATGGA GCTCATGGGA AGCAATTATC CACCTCAAAA TGCAGTCAAA 
GCGTACACAC TGGATGGATC TCAAGCATAT GCTAATGGAC CAAATAGTCA GTATCGTTTC 
TACAGTGGTA GAGGAGGACA TGCACGTGGT ACTTTTGGAA ATGATCAGGG AGATGTTGAT 
GAAGGAGCAT TAGCCAGACT GATTGAAGAT ACTAAATCGG AAGCCATGAG ACTGGAAACT 
CAAGATTTGC GAAAACAAGA TCATGAGCTG AAAGTGATAT ATAATGAGCG TGATCAGACG 
AAAGCTGCAA TTGATGAATT CGATAGAAAA TTGTCAAATC TTCGATCTCA AGAATTGCAG 
AAAGAACGTC AGGCAAAAGA TTTGAGAGCA GAATTGGCGC AAACTGCGAA TGAAGATCAA 
GTGGAAAATC TGAATGAATC TATTGAGGAA ATGCAGAAAA AGATTCCTTT AATCGAGGAT 
GAAGTCAAAG ATATTCTGAA AAATGTGGCA GACATCACTG CAGACATGGC TCCAGTTATT 
CAAGAGAGGA AAGAAGCGGA ACATACGCTA GCGGAAATTC AAAAAGAAAC ACGAGATTTT 
GCAAGTAAAT CCCAGAAACT TCAAAACGAA TTGAGCAAGT ATGACGACGC CGGAGAGATT 
CTCAAAATTC GTCTCGATAA AGTGAAAGCT GACGAAGGTG TATTCTTCCA CACAGAGGCG 
AAACTCAAAT CTGAAAGAGA CGATGCGATG GAAATGGTGG AAAACGACAA AAAGAATCAT 
CCAATGCCAC CTGGCGAGAC AGATCCACCA GATCTTTCAA GTTTCCCGTC GACGACTGAA 
GCTCAGAGAA AGATCGAAGA AATGCAGAAA GCAGTTGACA GAGCAACAGT TGGATGTGAC 
ACTACTATTA CTCTTGAATG TGTTAAAGAC TTTAAAGATA AACTGAAAAG GTTGAAGTAT 
CTGTGTCGCA TGATTGAAGA TGTTCTCATC GAGCTTAAAA ATCTTCATGC AGCCCGTGTA 
AAAGCATATC CGAGCTTGAA AAAGTTCACG GAATTGAAGG TGTGTAACAA GTTCCAGGAG 
TTGCTCGCAG TTCGAGGTCA TTTTATCGGT GGTCTCGAAT TCGATCACGA GAAGGAGACA 
CTTAATGTGA ATGTTCAATC TTCTAAAGAG AAGGATGCGA TGGCTGGACG AAGACCTGAA 
GTCCTTGAGG TAGAAGAAGT CGACGAGCAT TCGTATGATG ATGATAGTGA CGATAGTACC 
GGTCCGCGTA GAAAGAAGTC CAAGAAGAGC GGCCAGAAAA AGAAGAGAGT TCGTGATCTG 
AAAGGATTAT CCGGAGGAGA ACGGTCTTTT GTGACTGCCG CACTCGTCAT GTCCTTGTGG 
GAAGTTATGG AGCAGCCATT CCGAATGATG GATGAGTTTG ATGTCTTTAT GGACATGATG 
AATAGAAAGC TGGTGATGGA TTTGCTCGTC GAGCTGGCCA CCAAGAAGTT CCCTCACAAT 
CAGTTCATCT TCTTCACTCC ACAAGGAATC AAGGAACTCA ACATGGTCGA TGGTCTTCAA 
GTTTTCGAGA TGAACAGAGT CCGCGACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)

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smc-6 cDNA ORF clone, Caenorhabditis elegans

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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