Gene Symbol | hsf-1 |
Entrez Gene ID | 173078 |
Full Name | Heat Shock Factor |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » hsf-1 cDNA ORF clone
Gene Symbol | hsf-1 |
Entrez Gene ID | 173078 |
Full Name | Heat Shock Factor |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_060630.4 | NP_493031.1 | HSF_DOMAIN domain-containing protein |
NM_060630.3 | NP_493031.1 | Heat Shock Factor |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
These functions of HPK-1/HSF-1 undergo rapid down-regulation once animals reach reproductive maturity. We show that HPK-1 fortifies proteostasis and extends longevity by an additional independent mechanism: induction of autophagy.
Title: The homeodomain-interacting protein kinase HPK-1 preserves protein homeostasis and longevity through master regulatory control of the HSF-1 chaperone network and TORC1-restricted autophagy in Caenorhabditis elegans.
Diminution in phenotypic variation for both gene expression and life span at 25 degrees C may be a consequence of low level hsf-1-dependent expression of HSP-16.2 and other chaperones at the higher temperature.
Title: Environmental Canalization of Life Span and Gene Expression in Caenorhabditis elegans.
We demonstrate that while DAF-16/FOXO is dispensable, the age-dependent suppression of cilia phenotypes in IFT mutants requires cell-autonomous functions of the HSF1 heat shock factor and the Hsp90 chaperone
Title: Structural and Functional Recovery of Sensory Cilia in C. elegans IFT Mutants upon Aging.
HSF-1 is a codeterminant of both alcohol and nicotine sensitivity in C. elegans and that this phenotype requires the small HSP, HSP-16.48. HSP-16.48 function in drug sensitivity is unrelated to a chaperone action during the heat shock stress response.
Title: Small Heat Shock Proteins Are Novel Common Determinants of Alcohol and Nicotine Sensitivity in Caenorhabditis elegans.
Heat-stress-enhanced ascaroside production appears to be mediated at least in part by HSF-1, which seems to be important in adaptation strategies for coping with heat stress in this nematode.
Title: HSF-1 is involved in regulation of ascaroside pheromone biosynthesis by heat stress in Caenorhabditis elegans.
The following hsf-1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the hsf-1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa336045 | |
Clone ID Related Accession (Same CDS sequence) | NM_060630.4 , NM_060630.3 | |
Accession Version | NM_060630.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2016bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | HSF_DOMAIN domain-containing protein | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Sep 4, 2019 this sequence version replaced NM_060630.3. |
1 | ATGCAGCCAA CAGGGAATCA AATACAACAA AACCAGCAAC AACAGCAACA ACTGATAATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_493031.1 |
CDS | 23..2038 |
Translation |
Target ORF information:
Target ORF information:
|
NM_060630.4 |
1 | ATGCAGCCAA CAGGGAATCA AATACAACAA AACCAGCAAC AACAGCAACA ACTGATAATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa336045 | |
Clone ID Related Accession (Same CDS sequence) | NM_060630.4 , NM_060630.3 | |
Accession Version | NM_060630.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2016bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Heat Shock Factor | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Jun 26, 2012 this sequence version replaced NM_060630.2. COMPLETENESS: incomplete on both ends. |
1 | ATGCAGCCAA CAGGGAATCA AATACAACAA AACCAGCAAC AACAGCAACA ACTGATAATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_493031.1 |
CDS | 1..2016 |
Translation |
Target ORF information:
Target ORF information:
|
NM_060630.3 |
1 | ATGCAGCCAA CAGGGAATCA AATACAACAA AACCAGCAAC AACAGCAACA ACTGATAATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |