Gene Symbol | pop-1 |
Entrez Gene ID | 171849 |
Full Name | Protein pop-1 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » pop-1 cDNA ORF clone
Gene Symbol | pop-1 |
Entrez Gene ID | 171849 |
Full Name | Protein pop-1 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_058652.3 | NP_491053.4 | Protein pop-1 |
NM_058652.4 | NP_491053.4 | Protein pop-1 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
these results indicate that SYS-1 and POP-1 levels are influenced by the parent cell's SYS-1/POP-1 levels and this may provide an additional mechanism by which POP-1 regulates distinct targets in different developmental contexts.
Title: Quantitative Differences in Nuclear ?-catenin and TCF Pattern Embryonic Cells in C. elegans.
we demonstrate that POP-1 (the C. elegans TCF) also activates target genes through HMG and Helper site interactions.
Title: Distinct DNA binding sites contribute to the TCF transcriptional switch in C. elegans and Drosophila.
SYS-1 and POP-1 nuclear levels are regulated in opposite directions; the C terminus of POP-1 is essential for LIT-1 phosphorylation and is specifically bound by the diverged beta-catenin WRM-1
Title: Distinct and mutually inhibitory binding by two divergent ?-catenins coordinates TCF levels and activity in C. elegans.
Animals with reduced function of the Wnt-pathway downstream effector POP-1 have as many as 67 seam cells. The 'Wnt/beta-catenin asymmetry' pathway is required for the proper stem cell-like asymmetric division of seam cells.
Title: Wnt signaling controls the stem cell-like asymmetric division of the epithelial seam cells during C. elegans larval development.
Study suggests that pop-1 is not critical for mesoderm specification beyond repression of endoderm specification, and reveals that Wnt-modified pop-1 further reinforces endoderm specification by repressing mesoderm fate in endoderm.
Title: Roles of the Wnt effector POP-1/TCF in the C. elegans endomesoderm specification gene network.
The following pop-1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the pop-1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa335232 | |
Clone ID Related Accession (Same CDS sequence) | NM_058652.3 , NM_058652.4 | |
Accession Version | NM_058652.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1317bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Protein pop-1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Aug 9, 2005 this sequence version replaced NM_058652.2. COMPLETENESS: incomplete on both ends. |
1 | ATGATGGCCG ACGAAGAGCT CGGCGATGAG GTGAAGGTGT TCCGTCGGGA TGAGGATGCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_491053.4 |
CDS | 1..1317 |
Translation |
Target ORF information:
Target ORF information:
|
NM_058652.3 |
1 | ATGATGGCCG ACGAAGAGCT CGGCGATGAG GTGAAGGTGT TCCGTCGGGA TGAGGATGCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa335232 | |
Clone ID Related Accession (Same CDS sequence) | NM_058652.3 , NM_058652.4 | |
Accession Version | NM_058652.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1317bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Protein pop-1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Sep 4, 2019 this sequence version replaced NM_058652.3. |
1 | ATGATGGCCG ACGAAGAGCT CGGCGATGAG GTGAAGGTGT TCCGTCGGGA TGAGGATGCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_491053.4 |
CDS | 19..1335 |
Translation |
Target ORF information:
Target ORF information:
|
NM_058652.4 |
1 | ATGATGGCCG ACGAAGAGCT CGGCGATGAG GTGAAGGTGT TCCGTCGGGA TGAGGATGCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |