Gene Symbol | bli-3 |
Entrez Gene ID | 171608 |
Full Name | Dual oxidase 1 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » bli-3 cDNA ORF clone
Gene Symbol | bli-3 |
Entrez Gene ID | 171608 |
Full Name | Dual oxidase 1 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_058285.5 | NP_490686.3 | Dual oxidase 1 |
NM_058285.4 | NP_490686.3 | Dual oxidase 1 |
LOC713906 | XP_001103398.2 | |
Canis lupus familiaris (dog) | DUOX2 | XP_005638424.1 |
Rattus norvegicus (Norway rat) | Duox2 | NP_077055.1 |
Bos taurus (cattle) | DUOX2 | XP_002690988.2 |
Homo sapiens (human) | DUOX2 | NP_054799.4 |
Drosophila melanogaster (fruit fly) | Duox | NP_001259968.1 |
Anopheles gambiae (African malaria mosquito) | DUOX | XP_319115.4 |
Caenorhabditis elegans (roundworm) | bli-3 | NP_490686.3 |
Pan troglodytes (chimpanzee) | DUOX2 | XP_510367.3 |
Arabidopsis thaliana (thale cress) | RBOHB | NP_973799.1 |
Mus musculus (house mouse) | Duox2 | NP_808278.2 |
Caenorhabditis elegans (roundworm) | duox-2 | NP_490684.1 |
Xenopus tropicalis (tropical clawed frog) | duox2 | XP_002937935.1 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
proline catabolism governs reactive oxygen species (ROS) homeostasis and subsequent activation of SKN-1, a critical transcription factor regulating xenobiotic stress response and pathogen defense. Intriguingly, proline catabolism-mediated activation of SKN-1 requires cell-membrane dual-oxidase Ce-Duox1/BLI-3, highlighting the importance of interaction between mitochondrial and cell-membrane components in host defense.
Title: Proline Catabolism Modulates Innate Immunity in Caenorhabditis elegans.
BLI-3/TSP-15/DOXA-1 dual oxidase complex is required for the toxic pleiotropic effects of excess iodide.
Title: The BLI-3/TSP-15/DOXA-1 dual oxidase complex is required for iodide toxicity in Caenorhabditis elegans.
We demonstrated that TSP-15, BLI-3, and DOXA-1 form complexes in vitro and in vivo. Cell-fusion-based analysis suggested that association with TSP-15 at the cell surface is crucial for BLI-3 activation to release H(2)O(2).
Title: Tetraspanin is required for generation of reactive oxygen species by the dual oxidase system in Caenorhabditis elegans.
ROS generation by Ce-Duox1/BLI-3 activates a protective SKN-1 response via p38 MAPK signaling.
Title: Ce-Duox1/BLI-3 generated reactive oxygen species trigger protective SKN-1 activity via p38 MAPK signaling during infection in C. elegans.
study of mutations of the DUOX1 truncated peroxidase domain to investigate possible role of the distal tyrosyl residue in heme binding; result argues that the DUOX peroxidase domain is primarily responsible for tyrosine cross-linking
Title: Perturbed heme binding is responsible for the blistering phenotype associated with mutations in the Caenorhabditis elegans dual oxidase 1 (DUOX1) peroxidase domain.
The following bli-3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the bli-3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa337013 | |
Clone ID Related Accession (Same CDS sequence) | NM_058285.5 , NM_058285.4 | |
Accession Version | NM_058285.5 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 4494bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Dual oxidase 1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Sep 4, 2019 this sequence version replaced NM_058285.4. |
1 | ATGCGCTCAA AACATGTGCT GTACATAGCT ATACTGTTCA GTTCAATTTT TGGAGGGAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_490686.3 |
CDS | 37..4530 |
Translation |
Target ORF information:
Target ORF information:
|
NM_058285.5 |
1 | ATGCGCTCAA AACATGTGCT GTACATAGCT ATACTGTTCA GTTCAATTTT TGGAGGGAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa337013 | |
Clone ID Related Accession (Same CDS sequence) | NM_058285.5 , NM_058285.4 | |
Accession Version | NM_058285.4 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 4494bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Dual oxidase 1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Jun 26, 2012 this sequence version replaced NM_058285.3. COMPLETENESS: incomplete on both ends. |
1 | ATGCGCTCAA AACATGTGCT GTACATAGCT ATACTGTTCA GTTCAATTTT TGGAGGGAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_490686.3 |
CDS | 1..4494 |
Translation |
Target ORF information:
Target ORF information:
|
NM_058285.4 |
1 | ATGCGCTCAA AACATGTGCT GTACATAGCT ATACTGTTCA GTTCAATTTT TGGAGGGAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |