PEX18 cDNA ORF clone, Saccharomyces cerevisiae S288C

Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)

Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII.
Johnston M, Andrews S, Brinkman R, Cooper J, Ding H, Dover J, Du Z, Favello A, Fulton L, Gattung S
Science (New York, N.Y.)265(5181)2077-82(1994 Sep)

polyubiquitination of Pex18p requires Ubc4p, which cooperates with Pex2p and Pex10p. Monoubiquitination of Pex18p depends on Pex4p (Ubc10p) in concert with Pex12p and Pex10p.
Title: Distinct ubiquitination cascades act on the peroxisomal targeting signal type 2 co-receptor Pex18p.

The finding indicates that Pex18p export is linked to cargo translocation, which supports the idea of an export-driven import of proteins into peroxisomes.
Title: Cysteine-dependent ubiquitination of Pex18p is linked to cargo translocation across the peroxisomal membrane.

Data revealed that both PTS-receptors as well as the auxiliary proteins Pex18p and Pex21p are neither required for Pex8p association with the importomer nor for its function as an organizer of the peroxisomal protein import machinery.
Title: Targeting of Pex8p to the peroxisomal importomer.

Data suggest that the N-terminal half of Pex5p facilitates the import of the major matrix protein Fox1p, and can be functionally replaced by Pex18p.
Title: Functional similarity between the peroxisomal PTS2 receptor binding protein Pex18p and the N-terminal half of the PTS1 receptor Pex5p.