Gene Symbol | PAN2 |
Entrez Gene ID | 852786 |
Full Name | poly(A)-specific ribonuclease |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » PAN2 cDNA ORF clone
Gene Symbol | PAN2 |
Entrez Gene ID | 852786 |
Full Name | poly(A)-specific ribonuclease |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001180959.1 | NP_011421.1 | poly(A)-specific ribonuclease |
Rattus norvegicus (Norway rat) | Pan2 | NP_001008862.1 |
Kluyveromyces lactis | KLLA0E18877g | XP_454804.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_17449 | XP_003718602.1 |
Neurospora crassa | NCU10733 | XP_001728299.1 |
Pan troglodytes (chimpanzee) | LOC451995 | XP_003952222.1 |
Saccharomyces cerevisiae (baker's yeast) | PAN2 | NP_011421.1 |
PAN2 | XP_001114990.2 | |
Canis lupus familiaris (dog) | PAN2 | XP_531635.3 |
Danio rerio (zebrafish) | LOC792831 | XP_001920000.4 |
Homo sapiens (human) | PAN2 | NP_001159751.1 |
Bos taurus (cattle) | PAN2 | NP_001073078.2 |
Gallus gallus (chicken) | PAN2 | NP_001012972.1 |
Drosophila melanogaster (fruit fly) | CG8232 | NP_610427.2 |
Schizosaccharomyces pombe (fission yeast) | ubp13 | NP_593053.2 |
Xenopus tropicalis (tropical clawed frog) | pan2 | XP_002934576.2 |
Mus musculus (house mouse) | Pan2 | NP_598753.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP010626 | XP_310122.4 |
Eremothecium gossypii | AGOS_AFL055W | NP_985493.2 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome VII.
Tettelin H, Agostoni Carbone ML, Albermann K, Albers M, Arroyo J, Backes U, Barreiros T, Bertani I, Bjourson AJ, Br?ckner M, Bruschi CV, Carignani G, Castagnoli L, Cerdan E, Clemente ML, Coblenz A, Coglievina M, Coissac E, Defoor E, Del Bino S, Delius H, Delneri D, de Wergifosse P, Dujon B, Kleine K
Nature387(6632 Suppl)81-4(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The exonuclease subunit Pan2 does not bind RNA by itself, but binds to an asymmetric Pan3 homodimer via an extensive, high-affinity interaction.
Title: Structural basis for Pan3 binding to Pan2 and its function in mRNA recruitment and deadenylation.
PAN2 and PAN3 are not required for mRNA poly(A) tail length control during de novo synthesis but may act in conjuction with Pab1p at a later stage in mRNA metabolism.
Title: Yeast mRNA Poly(A) tail length control can be reconstituted in vitro in the absence of Pab1p-dependent Poly(A) nuclease activity.
Accumulation of polyadenylated mRNAs at sites of transcription occurs in strains lacking the PAN2 or PAN3 subunits of the poly(A) nuclease PAN. PAN is identified as an important factor that couples 3' processing of pre-mRNAs to export.
Title: Yeast poly(A)-binding protein, Pab1, and PAN, a poly(A) nuclease complex recruited by Pab1, connect mRNA biogenesis to export.
The following PAN2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PAN2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi02151 | |
Clone ID Related Accession (Same CDS sequence) | NM_001180959.1 | |
Accession Version | NM_001180959.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3348bp) Protein sequence SNP |
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Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | poly(A)-specific ribonuclease | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001139). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGAATAATT GGCAACATTT CTTCAACAAT CCAGTTGATC TTTCGGAACA TTTGAAGAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_011421.1 |
CDS | 1..3348 |
Translation |
Target ORF information:
Target ORF information:
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1 | ATGAATAATT GGCAACATTT CTTCAACAAT CCAGTTGATC TTTCGGAACA TTTGAAGAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome VII. |
Life with 6000 genes. |