Gene Symbol | cdc48 |
Entrez Gene ID | 2542744 |
Full Name | AAA family ATPase Cdc48 |
Gene Type | protein-coding |
Organism | Schizosaccharomyces pombe(fission yeast) |
ORF » Species Summary » Schizosaccharomyces pombe » cdc48 cDNA ORF clone
Gene Symbol | cdc48 |
Entrez Gene ID | 2542744 |
Full Name | AAA family ATPase Cdc48 |
Gene Type | protein-coding |
Organism | Schizosaccharomyces pombe(fission yeast) |
mRNA | Protein | Name |
---|---|---|
NM_001018717.2 | NP_593287.2 | AAA family ATPase Cdc48 |
Pan troglodytes (chimpanzee) | VCP | XP_003312111.1 |
Gallus gallus (chicken) | VCP | NP_001038129.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_05193 | XP_003712735.1 |
Canis lupus familiaris (dog) | VCP | XP_852626.1 |
Bos taurus (cattle) | VCP | NP_001029466.1 |
Mus musculus (house mouse) | Vcp | NP_033529.3 |
Drosophila melanogaster (fruit fly) | TER94 | NP_477369.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP005630 | XP_315644.3 |
Saccharomyces cerevisiae (baker's yeast) | CDC48 | NP_010157.1 |
Schizosaccharomyces pombe (fission yeast) | cdc48 | NP_593287.2 |
Neurospora crassa | NCU00018 | XP_957005.2 |
Arabidopsis thaliana (thale cress) | AT3G53230 | NP_190891.1 |
Rattus norvegicus (Norway rat) | Vcp | NP_446316.1 |
Danio rerio (zebrafish) | vcp | NP_958889.1 |
Kluyveromyces lactis | KLLA0F05676g | XP_455337.1 |
Arabidopsis thaliana (thale cress) | AT5G03340 | NP_568114.1 |
Oryza sativa (rice) | Os03g0151800 | NP_001048987.1 |
Xenopus tropicalis (tropical clawed frog) | vcp | NP_001005677.1 |
Caenorhabditis elegans (roundworm) | cdc-48.1 | NP_496273.1 |
Caenorhabditis elegans (roundworm) | cdc-48.2 | NP_495705.1 |
Arabidopsis thaliana (thale cress) | CDC48 | NP_187595.1 |
Homo sapiens (human) | VCP | NP_009057.1 |
Eremothecium gossypii | AGOS_AFR158W | NP_985705.2 |
The genome sequence of Schizosaccharomyces pombe.
Wood V, Gwilliam R, Rajandream MA, Lyne M, Lyne R, Stewart A, Sgouros J, Peat N, Hayles J, Baker S, Basham D, Bowman S, Brooks K, Brown D, Brown S, Chillingworth T, Churcher C, Collins M, Connor R, Cronin A, Davis P, Feltwell T, Fraser A, Gentles S, Goble A, Hamlin N, Harris D, Hidalgo J, Hodgson G, Holroyd S, Hornsby T, Howarth S, Huckle EJ, Hunt S, Jagels K, James K, Jones L, Jones M, Leather S, McDonald S, McLean J, Mooney P, Moule S, Mungall K, Murphy L, Niblett D, Odell C, Oliver K, O'Neil S, Pearson D, Quail MA, Rabbinowitsch E, Rutherford K, Rutter S, Saunders D, Seeger K, Sharp S, Skelton J, Simmonds M, Squares R, Squares S, Stevens K, Taylor K, Taylor RG, Tivey A, Walsh S, Warren T, Whitehead S, Woodward J, Volckaert G, Aert R, Robben J, Grymonprez B, Weltjens I, Vanstreels E, Rieger M, Sch?fer M, M?ller-Auer S, Gabel C, Fuchs M, D?sterh?ft A, Fritzc C, Holzer E, Moestl D, Hilbert H, Borzym K, Langer I, Beck A, Lehrach H, Reinhardt R, Pohl TM, Eger P, Zimmermann W, Wedler H, Wambutt R, Purnelle B, Goffeau A, Cadieu E, Dr?ano S, Gloux S, Lelaure V, Mottier S, Galibert F, Aves SJ, Xiang Z, Hunt C, Moore K, Hurst SM, Lucas M, Rochet M, Gaillardin C, Tallada VA, Garzon A, Thode G, Daga RR, Cruzado L, Jimenez J, S?nchez M, del Rey F, Benito J, Dom?nguez A, Revuelta JL, Moreno S, Armstrong J, Forsburg SL, Cerutti L, Lowe T, McCombie WR, Paulsen I, Potashkin J, Shpakovski GV, Ussery D, Barrell BG, Nurse P, Cerrutti L
Nature415(6874)871-80(2002 Feb)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Data suggest that cdc48 cofactor ufd1 is required for SREBP1/2 cleavage/activation but does not interact with cdc48-rbd2 complex; cdc48-ufd1 is instead required at step prior to rbd2 function, during Golgi localization of dsc1-E3 ligase. (cdc48 = AAA family ATPase cdc48; ufd1 = cdc48-ufd1-npl4 complex component ufd1; dsc1-E3 ligase = ubiquitin-protein ligase E3; SREBP1/2 = sterol regulatory element binding proteins 1/2)
Title: Dsc E3 ligase localization to the Golgi requires the ATPase Cdc48 and cofactor Ufd1 for activation of sterol regulatory element-binding protein in fission yeast.
Data show that cell cycle protein Cdc48-353 mutant is structurally compromized at the restrictive temperature.
Title: Single site suppressors of a fission yeast temperature-sensitive mutant in cdc48 identified by whole genome sequencing.
a new signaling mechanism involving dual recruitment by SUMO and ubiquitin for Cdc48-Ufd1-Npl4 functions in maintaining genome stability.
Title: Dual recruitment of Cdc48 (p97)-Ufd1-Npl4 ubiquitin-selective segregase by small ubiquitin-like modifier protein (SUMO) and ubiquitin in SUMO-targeted ubiquitin ligase-mediated genome stability functions.
Results suggest that Cdc48, Yin6 and Moe1 act in the same protein complex to concertedly control ERAD and chromosome segregation.
Title: Int6 and Moe1 interact with Cdc48 to regulate ERAD and proper chromosome segregation.
The following cdc48 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the cdc48 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSc101807 | |
Clone ID Related Accession (Same CDS sequence) | NM_001018717.2 | |
Accession Version | NM_001018717.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2448bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-04-02 | |
Organism | Schizosaccharomyces pombe(fission yeast) | |
Product | AAA family ATPase Cdc48 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. This record is derived from an annotated genomic sequence (NC_003424). On Dec 10, 2012 this sequence version replaced NM_001018717.1. COMPLETENESS: incomplete on the 5' end. |
1 | ATGAACGCAC CATCCACCAT GACCGATAAG AAACCAGAAG TGGAACACCT TCAGGGTGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_593287.2 |
CDS | 1..2448 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001018717.2 |
1 | ATGAACGCAC CATCCACCAT GACCGATAAG AAACCAGAAG TGGAACACCT TCAGGGTGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The genome sequence of Schizosaccharomyces pombe. |