HSK cDNA ORF clone, Arabidopsis thaliana(thale cress)

Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.
Lin X, Kaul S, Rounsley S, Shea TP, Benito MI, Town CD, Fujii CY, Mason T, Bowman CL, Barnstead M, Feldblyum TV, Buell CR, Ketchum KA, Lee J, Ronning CM, Koo HL, Moffat KS, Cronin LA, Shen M, Pai G, Van Aken S, Umayam L, Tallon LJ, Gill JE, Adams MD, Carrera AJ, Creasy TH, Goodman HM, Somerville CR, Copenhaver GP, Preuss D, Nierman WC, White O, Eisen JA, Salzberg SL, Fraser CM, Venter JC
Nature402(6763)761-8(1999 Dec)

The dmr1-2 mutant allele confers increased resistance to Fusarium culmorum and F. graminearum silique infection, and decreased colonisation of rosette leaves. The dmr1-1 allele supports less rosette leaf colonisation but has wild type silique resistance.
Title: Mutations in the Arabidopsis homoserine kinase gene DMR1 confer enhanced resistance to Fusarium culmorum and F. graminearum.

Data indicate that pathogen resistance by impairment of PMR4 (callose synthase 12) and DMR1 (homoserine kinase) is conserved between Arabidopsis and Tomato.
Title: Powdery mildew resistance in tomato by impairment of SlPMR4 and SlDMR1.

Six independent dmr1 mutants each carry a different amino acid substitution in the HSK protein. Data provide evidence that homoserine accumulation in the chloroplast triggers a novel form of downy mildew resistance.
Title: Downy mildew resistance in Arabidopsis by mutation of HOMOSERINE KINASE.

HSK overexpression had no effect on the level of soluble homoserine phosphate, methionine and threonine/me
Title: Methionine and threonine synthesis are limited by homoserine availability and not the activity of homoserine kinase in Arabidopsis thaliana.