hpo cDNA ORF clone, Neurospora crassa OR74A

Gene
Clones
gRNAs

Summary

Gene Symbol	hpo
Entrez Gene ID	3873819
Full Name	heterochromatin protein
Synonyms	HP1
Gene Type	protein-coding
Organism	Neurospora crassa OR74A

mRNA and Protein(s)

mRNA	Protein	Name
XM_952539.3	XP_957632.1	heterochromatin protein 1

Pathways from BioSystems

Homologies

Magnaporthe oryzae (rice blast fungus)	MGG_04964	XP_003712460.1
Neurospora crassa	NCU04017	XP_957632.1

Gene Ontology
Bibliography

Related articles in PubMed

The genome sequence of the filamentous fungus Neurospora crassa.
Galagan JE, Calvo SE, Borkovich KA, Selker EU, Read ND, Jaffe D, FitzHugh W, Ma LJ, Smirnov S, Purcell S, Rehman B, Elkins T, Engels R, Wang S, Nielsen CB, Butler J, Endrizzi M, Qui D, Ianakiev P, Bell-Pedersen D, Nelson MA, Werner-Washburne M, Selitrennikoff CP, Kinsey JA, Braun EL, Zelter A, Schulte U, Kothe GO, Jedd G, Mewes W, Staben C, Marcotte E, Greenberg D, Roy A, Foley K, Naylor J, Stange-Thomann N, Barrett R, Gnerre S, Kamal M, Kamvysselis M, Mauceli E, Bielke C, Rudd S, Frishman D, Krystofova S, Rasmussen C, Metzenberg RL, Perkins DD, Kroken S, Cogoni C, Macino G, Catcheside D, Li W, Pratt RJ, Osmani SA, DeSouza CP, Glass L, Orbach MJ, Berglund JA, Voelker R, Yarden O, Plamann M, Seiler S, Dunlap J, Radford A, Aramayo R, Natvig DO, Alex LA, Mannhaupt G, Ebbole DJ, Freitag M, Paulsen I, Sachs MS, Lander ES, Nusbaum C, Birren B
Nature422(6934)859-68(2003 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Surprisingly, loss of either H3K9me3 or HP1 had only mild effects on heterochromatin compaction, whereas dim-3 caused more drastic changes, specifically decreasing interactions between constitutive heterochromatic domains
Title: Neurospora chromosomes are organized by blocks of importin alpha-dependent heterochromatin that are largely independent of H3K9me3.

The following hpo gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the hpo cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ONf04652	XM_952539.3 Latest version!	Neurospora crassa OR74A heterochromatin protein (hpo), 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

hpo ( XM_952539.3 ) cDNA ORF clone, Neurospora crassa OR74A -> XP_957632.1 Neurospora crassa OR74A heterochromatin protein (hpo), 1, mRNA.

Price & Availability↑

CloneID	ONf04652
Clone ID Related Accession (Same CDS sequence)	XM_952539.3
Accession Version	XM_952539.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 801bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-10
Organism	Neurospora crassa OR74A
Product	heterochromatin protein 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. This record is derived from an annotated genomic sequence (NC_026506). On Feb 23, 2015 this sequence version replaced XM_952539.2.

ATGCCGTACG ATCCATCGGC TCTCAGCGAC GAGGAGGCCG CCTCCAGTGT CGAGCTCGAC 
ACTCGCTCGG CTACCTCGAG CAGCAAGAAA CAGTCTCGCG ACAAAAAGTC CGTCAAGTAC 
ACAATTCCAG AGCCCGAGGA CTTTGAGGAC GAGGAACAAA ACGGAGACGG CGCCGATGAG 
GGCGGTGAGG ATGACGAGGA AGGTGACGAG GAGGAGGAGG ACGTCTACGT CGTCGAGAAA 
ATCCTCGACC ATATGCTTAA CGACGATAAC GAGCCACTCT TCCTCGTGAA GTGGGAGGGT 
TACGAGAAAA AGTCTGACCA GACCTGGGAG CCTGAGGACA CTTTGATAGA GGGCGCGTCG 
GAGAGGCTCA AGGAGTACTT TACCAAGATT GGCGGTCGAG AGAAGATTTT CGAAGCTTCC 
GCTGCGGCGC AGAAGATCAA GAAGCGTGGC CGGCCCTCTT CAAACTCCGG CACTCCCCAA 
GCAAGCAGCA ACAAACGGTC GAGGAAGAAC GGCGACCATC CCCTTAACTC TGAGGAGCCC 
CAGACCGCTA AGAACGCTGC CTGGAAGCCC CCAGCGGGAA GCTGGGAAGA GCATATTGCT 
CAACTCGATG CCTGCGAAGA TGAGGACACA CACAAGCTCA TGGTTTATCT GACGTGGAAG 
AATGGCCACA AGACCCAGCA TACAACTGAC GTCATCTACA AGAGGTGCCC CCAAAAGATG 
CTCCAATTTT ATGAGCGACA TGTGAGGATT ATCAAGAGGG ACCCAGACTC CGAGGATCGC 
GAGGGCAGCG TCTCGCAATA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_957632.1
CDS	508..1308
Translation	MPYDPSALSDEEAASSVELDTRSATSSSKKQSRDKKSVKYTIPEPEDFEDEEQNGDGADEGGEDDEEGDEEEEDVYVVEKILDHMLNDDNEPLFLVKWEGYEKKSDQTWEPEDTLIEGASERLKEYFTKIGGREKIFEASAAAQKIKKRGRPSSNSGTPQASSNKRSRKNGDHPLNSEEPQTAKNAAWKPPAGSWEEHIAQLDACEDEDTHKLMVYLTWKNGHKTQHTTDVIYKRCPQKMLQFYERHVRIIKRDPDSEDREGSVSQ

Target ORF information:

RefSeq Version	XM_952539.3
Organism	Neurospora crassa OR74A
Definition	Neurospora crassa OR74A heterochromatin protein (hpo), 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_952539.3

ORF Insert Sequence:

ATGCCGTACG ATCCATCGGC TCTCAGCGAC GAGGAGGCCG CCTCCAGTGT CGAGCTCGAC 
ACTCGCTCGG CTACCTCGAG CAGCAAGAAA CAGTCTCGCG ACAAAAAGTC CGTCAAGTAC 
ACAATTCCAG AGCCCGAGGA CTTTGAGGAC GAGGAACAAA ACGGAGACGG CGCCGATGAG 
GGCGGTGAGG ATGACGAGGA AGGTGACGAG GAGGAGGAGG ACGTCTACGT CGTCGAGAAA 
ATCCTCGACC ATATGCTTAA CGACGATAAC GAGCCACTCT TCCTCGTGAA GTGGGAGGGT 
TACGAGAAAA AGTCTGACCA GACCTGGGAG CCTGAGGACA CTTTGATAGA GGGCGCGTCG 
GAGAGGCTCA AGGAGTACTT TACCAAGATT GGCGGTCGAG AGAAGATTTT CGAAGCTTCC 
GCTGCGGCGC AGAAGATCAA GAAGCGTGGC CGGCCCTCTT CAAACTCCGG CACTCCCCAA 
GCAAGCAGCA ACAAACGGTC GAGGAAGAAC GGCGACCATC CCCTTAACTC TGAGGAGCCC 
CAGACCGCTA AGAACGCTGC CTGGAAGCCC CCAGCGGGAA GCTGGGAAGA GCATATTGCT 
CAACTCGATG CCTGCGAAGA TGAGGACACA CACAAGCTCA TGGTTTATCT GACGTGGAAG 
AATGGCCACA AGACCCAGCA TACAACTGAC GTCATCTACA AGAGGTGCCC CCAAAAGATG 
CTCCAATTTT ATGAGCGACA TGTGAGGATT ATCAAGAGGG ACCCAGACTC CGAGGATCGC 
GAGGGCAGCG TCTCGCAATA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The genome sequence of the filamentous fungus Neurospora crassa.
Nature422(6934)859-68(2003 Apr)
Galagan JE,Calvo SE,Borkovich KA,Selker EU,Read ND,Jaffe D,FitzHugh W,Ma LJ,Smirnov S,Purcell S,Rehman B,Elkins T,Engels R,Wang S,Nielsen CB,Butler J,Endrizzi M,Qui D,Ianakiev P,Bell-Pedersen D,Nelson MA,Werner-Washburne M,Selitrennikoff CP,Kinsey JA,Braun EL,Zelter A,Schulte U,Kothe GO,Jedd G,Mewes W,Staben C,Marcotte E,Greenberg D,Roy A,Foley K,Naylor J,Stange-Thomann N,Barrett R,Gnerre S,Kamal M,Kamvysselis M,Mauceli E,Bielke C,Rudd S,Frishman D,Krystofova S,Rasmussen C,Metzenberg RL,Perkins DD,Kroken S,Cogoni C,Macino G,Catcheside D,Li W,Pratt RJ,Osmani SA,DeSouza CP,Glass L,Orbach MJ,Berglund JA,Voelker R,Yarden O,Plamann M,Seiler S,Dunlap J,Radford A,Aramayo R,Natvig DO,Alex LA,Mannhaupt G,Ebbole DJ,Freitag M,Paulsen I,Sachs MS,Lander ES,Nusbaum C,Birren B

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hpo cDNA ORF clone, Neurospora crassa OR74A

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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