Gene Symbol | KCNN4 |
Entrez Gene ID | 397081 |
Full Name | potassium calcium-activated channel subfamily N member 4 |
Synonyms | KCa3.1 |
Gene Type | protein-coding |
Organism | Sus scrofa(pig) |
ORF » Species Summary » Sus scrofa » KCNN4 cDNA ORF clone
Gene Symbol | KCNN4 |
Entrez Gene ID | 397081 |
Full Name | potassium calcium-activated channel subfamily N member 4 |
Synonyms | KCa3.1 |
Gene Type | protein-coding |
Organism | Sus scrofa(pig) |
mRNA | Protein | Name |
---|---|---|
NM_214018.2 | NP_999183.1 | intermediate conductance calcium-activated potassium channel protein 4 |
Local delivery of the KCa3.1 blocker, TRAM-34, prevents acute angioplasty-induced coronary smooth muscle phenotypic modulation and limits stenosis.
Tharp DL, Wamhoff BR, Wulff H, Raman G, Cheong A, Bowles DK
Arteriosclerosis, thrombosis, and vascular biology28(6)1084-9(2008 Jun)
Characterization of a charybdotoxin-sensitive intermediate conductance Ca2+-activated K+ channel in porcine coronary endothelium: relevance to EDHF.
Bychkov R, Burnham MP, Richards GR, Edwards G, Weston AH, F?l?tou M, Vanhoutte PM
British journal of pharmacology137(8)1346-54(2002 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Blockade of K(Ca)3.1 by delivery of TRAM-34 via balloon catheter prevented smooth muscle phenotypic modulation and limited subsequent restenosis in a swine model.
Title: Local delivery of the KCa3.1 blocker, TRAM-34, prevents acute angioplasty-induced coronary smooth muscle phenotypic modulation and limits stenosis.
The following KCNN4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the KCNN4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSe28881 | |
Clone ID Related Accession (Same CDS sequence) | NM_214018.2 | |
Accession Version | NM_214018.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1281bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-28 | |
Organism | Sus scrofa(pig) | |
Product | intermediate conductance calcium-activated potassium channel protein 4 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY062036.1. On Aug 31, 2012 this sequence version replaced NM_214018.1. ##Evidence-Data-START## Transcript exon combination :: AY062036.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01048242 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGGCGGGG AGCTGGTGCC GGGCCTAGGG GCCCTGCGGC GGCGAAAGCG CCTGCTGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_999183.1 |
CDS | 130..1410 |
Translation |
Target ORF information:
Target ORF information:
|
NM_214018.2 |
1 | ATGGGCGGGG AGCTGGTGCC GGGCCTAGGG GCCCTGCGGC GGCGAAAGCG CCTGCTGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Local delivery of the KCa3.1 blocker, TRAM-34, prevents acute angioplasty-induced coronary smooth muscle phenotypic modulation and limits stenosis. |
Characterization of a charybdotoxin-sensitive intermediate conductance Ca2+-activated K+ channel in porcine coronary endothelium: relevance to EDHF. |