MX2 cDNA ORF clone, Sus scrofa(pig)

Gene
Clones
gRNAs

Summary

Gene Symbol	MX2
Entrez Gene ID	396893
Full Name	myxovirus (influenza virus) resistance 2 (mouse)
Gene Type	protein-coding
Organism	Sus scrofa(pig)
Genome	Chromosome: 13 Map Location: 13\|13

mRNA and Protein(s)

mRNA	Protein	Name
NM_001097416.1	NP_001090885.1	interferon-induced GTP-binding protein Mx2

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

A single nucleotide polymorphism of porcine MX2 gene provides antiviral activity against vesicular stomatitis virus.
Sasaki K, Tungtrakoolsub P, Morozumi T, Uenishi H, Kawahara M, Watanabe T
Immunogenetics66(1)25-32(2014 Jan)

Molecular cloning and characterization of porcine Mx2 gene.
Morozumi T, Naito T, Lan PD, Nakajima E, Mitsuhashi T, Mikawa S, Hayashi T, Awata T, Uenishi H, Nagata K, Watanabe T, Hamasima N
Molecular immunology46(5)858-65(2009 Feb)

Polymorphisms in the promoter region of the porcine antiviral MX1 and MX2 genes.
Tungtrakoolsub P, Noda T, Morozumi T, Hamasima N, Kobayashi E, Ueda J, Watanabe T
Animal genetics39(1)22-7(2008 Feb)

PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences.
Uenishi H, Eguchi-Ogawa T, Shinkai H, Okumura N, Suzuki K, Toki D, Hamasima N, Awata T
Nucleic acids research35(Database issue)D650-3(2007 Jan)

Genomic structure, promoter analysis, and expression of the porcine (Sus scrofa) Mx1 gene.
Thomas AV, Palm M, Broers AD, Zezafoun H, Desmecht DJ
Immunogenetics58(5-6)383-9(2006 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

A single nucleotide polymorphism of porcine MX2 gene provides antiviral activity against vesicular stomatitis virus.
Title: A single nucleotide polymorphism of porcine MX2 gene provides antiviral activity against vesicular stomatitis virus.

The 341-bp MX2 promoter region contained regulatory sequences for ISRE, GC box, Sp1 and AP-1, as well as a TATA box. Nucleotide sequences of the MX2 promoter region revealed four substitutions and one deletion, in which six genotypes were classified.
Title: Polymorphisms in the promoter region of the porcine antiviral MX1 and MX2 genes.

The porcine Mx1 gene and promoter share the major structural and functional characteristics displayed by their homologs described in cattle, mouse, chicken, and man.
Title: Genomic structure, promoter analysis, and expression of the porcine (Sus scrofa) Mx1 gene.

Expression of Mx protein and interferon-alpha (IFN-alpha) was examined by immunohistochemistry in pigs experimentally infected with swine influenza virus.
Title: Expression of Mx protein and interferon-alpha in pigs experimentally infected with swine influenza virus.

The following MX2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MX2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OSe00377	NM_001097416.1 Latest version!	Sus scrofa myxovirus (influenza virus) resistance 2 (mouse) (MX2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

MX2 ( NM_001097416.1 ) cDNA ORF clone, Sus scrofa(pig) -> NP_001090885.1 Sus scrofa myxovirus (influenza virus) resistance 2 (mouse) (MX2), mRNA.

Price & Availability↑

CloneID	OSe00377
Clone ID Related Accession (Same CDS sequence)	NM_001097416.1
Accession Version	NM_001097416.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1170bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Sus scrofa(pig)
Product	interferon-induced GTP-binding protein Mx2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY897395.1. ##Evidence-Data-START## Transcript exon combination :: AY897395.1, AK345001.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN02904337 [ECO:0000350] ##Evidence-Data-END##

ATGCCTAAAC CCCGCATGTC GTGGCCTTAC CAACGTCATA GGCAGGCTTC TTCCCCACCT 
CATCCCCACA AAGAAATGAA TTTCTTCCCG CAGCAGCCTT TGCCCCTGGG CTCAGGCCCA 
GGGCAGATGA CCTTCCCTCT AAACTGGCAG ATGGGTGGGA AGGACCTCAC CAAGGGCCTG 
AATATGCTGA CCTTGAGCCC TCAGCAGCCC GGGGGAAAGA GTGGCCAGCA GACGTCAAAG 
GGGCCCGAGA ACAACCTGTA CAGCCCGTTC GAGGAGAAGG TGCGGCCCTG CATCGACCTC 
ATCGACTCGC TGCGGGCCCT GGGCGTGGAG CAGGACCTGG CCCTGCCCAC CATCGCCGTC 
ATCGGGGACC AGAGTTCGGG CAAGAGCTCC GTGCTGGAGG CCCTGTCGGG GGTCCCTCTC 
CCCAGAGGCA GCGGAATCAT CACCAGGTGT CCGCTAGCCC TGAGGCTGAA AAAGAAGGAG 
TGTCCGTGGC AGGGGAGGAT CAGCTACCGC AAAGTGGAGC TCCAGCTGCA AGACCCCTCC 
CAGGTGGAGC GGGAAATACG CAAAGCCCAG GATGCCATCG CTGGGAGCGG AGTTGGCATC 
AGCCACGAGC TCATCAGTCT GGAGGTCACC TCCCCGGAGG TTCCAGACCT GACCCTCATC 
GATCTTCCCG GCATCACCAG GGTGGCCGTG GGCAACCAGC CCCAGGACAT CGGACTGCAG 
ATCAAGGCGC TCATCAGGAA GTACATCCAG GAGCAGCAGA CCATCAACTT GGTGGTGGTC 
CCCTGCAACG TGGACATCGC CACCACGGAG GCGCTGCGCA TGGCCCAGGA GGTGGACCCC 
GAAGGAGACA GGACCATCGG GATCCTGACC AAACCAGATC TGGTGGACAC AGGCGCCGAG 
AAAGTTGTCC TGAATGTGAT GCAGAACCTC ACATACCATC TCAAGAAGGG CTACATGATA 
GTGAAGTGCC GCGGCCAGCA GGAGATCTTG AACAAGCTGA GCCTGGCCGA GGCAACCAAG 
AGGGAAATCG CATTCTTTCA CTCGCATCCG CACTTCAGAA TCCTGCTGGA GGAAGGAAAG 
GCCACAGTGC CTCGTCTGGC AGAACGACTC ACCGTCGAGC TCATCGGGCA TATCAGTGTG 
AGTTGGTGGG TTGAGGTACA AGGGATGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001090885.1
CDS	224..1393
Translation	MPKPRMSWPYQRHRQASSPPHPHKEMNFFPQQPLPLGSGPGQMTFPLNWQMGGKDLTKGLNMLTLSPQQPGGKSGQQTSKGPENNLYSPFEEKVRPCIDLIDSLRALGVEQDLALPTIAVIGDQSSGKSSVLEALSGVPLPRGSGIITRCPLALRLKKKECPWQGRISYRKVELQLQDPSQVEREIRKAQDAIAGSGVGISHELISLEVTSPEVPDLTLIDLPGITRVAVGNQPQDIGLQIKALIRKYIQEQQTINLVVVPCNVDIATTEALRMAQEVDPEGDRTIGILTKPDLVDTGAEKVVLNVMQNLTYHLKKGYMIVKCRGQQEILNKLSLAEATKREIAFFHSHPHFRILLEEGKATVPRLAERLTVELIGHISVSWWVEVQGM

Target ORF information:

RefSeq Version	NM_001097416.1
Organism	Sus scrofa(pig)
Definition	Sus scrofa myxovirus (influenza virus) resistance 2 (mouse) (MX2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001097416.1

ORF Insert Sequence:

ATGCCTAAAC CCCGCATGTC GTGGCCTTAC CAACGTCATA GGCAGGCTTC TTCCCCACCT 
CATCCCCACA AAGAAATGAA TTTCTTCCCG CAGCAGCCTT TGCCCCTGGG CTCAGGCCCA 
GGGCAGATGA CCTTCCCTCT AAACTGGCAG ATGGGTGGGA AGGACCTCAC CAAGGGCCTG 
AATATGCTGA CCTTGAGCCC TCAGCAGCCC GGGGGAAAGA GTGGCCAGCA GACGTCAAAG 
GGGCCCGAGA ACAACCTGTA CAGCCCGTTC GAGGAGAAGG TGCGGCCCTG CATCGACCTC 
ATCGACTCGC TGCGGGCCCT GGGCGTGGAG CAGGACCTGG CCCTGCCCAC CATCGCCGTC 
ATCGGGGACC AGAGTTCGGG CAAGAGCTCC GTGCTGGAGG CCCTGTCGGG GGTCCCTCTC 
CCCAGAGGCA GCGGAATCAT CACCAGGTGT CCGCTAGCCC TGAGGCTGAA AAAGAAGGAG 
TGTCCGTGGC AGGGGAGGAT CAGCTACCGC AAAGTGGAGC TCCAGCTGCA AGACCCCTCC 
CAGGTGGAGC GGGAAATACG CAAAGCCCAG GATGCCATCG CTGGGAGCGG AGTTGGCATC 
AGCCACGAGC TCATCAGTCT GGAGGTCACC TCCCCGGAGG TTCCAGACCT GACCCTCATC 
GATCTTCCCG GCATCACCAG GGTGGCCGTG GGCAACCAGC CCCAGGACAT CGGACTGCAG 
ATCAAGGCGC TCATCAGGAA GTACATCCAG GAGCAGCAGA CCATCAACTT GGTGGTGGTC 
CCCTGCAACG TGGACATCGC CACCACGGAG GCGCTGCGCA TGGCCCAGGA GGTGGACCCC 
GAAGGAGACA GGACCATCGG GATCCTGACC AAACCAGATC TGGTGGACAC AGGCGCCGAG 
AAAGTTGTCC TGAATGTGAT GCAGAACCTC ACATACCATC TCAAGAAGGG CTACATGATA 
GTGAAGTGCC GCGGCCAGCA GGAGATCTTG AACAAGCTGA GCCTGGCCGA GGCAACCAAG 
AGGGAAATCG CATTCTTTCA CTCGCATCCG CACTTCAGAA TCCTGCTGGA GGAAGGAAAG 
GCCACAGTGC CTCGTCTGGC AGAACGACTC ACCGTCGAGC TCATCGGGCA TATCAGTGTG 
AGTTGGTGGG TTGAGGTACA AGGGATGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A single nucleotide polymorphism of porcine MX2 gene provides antiviral activity against vesicular stomatitis virus.
Immunogenetics66(1)25-32(2014 Jan)
Sasaki K,Tungtrakoolsub P,Morozumi T,Uenishi H,Kawahara M,Watanabe T

Molecular cloning and characterization of porcine Mx2 gene.
Molecular immunology46(5)858-65(2009 Feb)
Morozumi T,Naito T,Lan PD,Nakajima E,Mitsuhashi T,Mikawa S,Hayashi T,Awata T,Uenishi H,Nagata K,Watanabe T,Hamasima N

Polymorphisms in the promoter region of the porcine antiviral MX1 and MX2 genes.
Animal genetics39(1)22-7(2008 Feb)
Tungtrakoolsub P,Noda T,Morozumi T,Hamasima N,Kobayashi E,Ueda J,Watanabe T

PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences.
Nucleic acids research35(Database issue)D650-3(2007 Jan)
Uenishi H,Eguchi-Ogawa T,Shinkai H,Okumura N,Suzuki K,Toki D,Hamasima N,Awata T

Genomic structure, promoter analysis, and expression of the porcine (Sus scrofa) Mx1 gene.
Immunogenetics58(5-6)383-9(2006 Jun)
Thomas AV,Palm M,Broers AD,Zezafoun H,Desmecht DJ