Gene Symbol | POU5F1 |
Entrez Gene ID | 100127461 |
Full Name | POU class 5 homeobox 1 |
Synonyms | OCT3,OCT4,Oct-4 |
Gene Type | protein-coding |
Organism | Sus scrofa(pig) |
Genome |
ORF » Species Summary » Sus scrofa » POU5F1 cDNA ORF clone
Gene Symbol | POU5F1 |
Entrez Gene ID | 100127461 |
Full Name | POU class 5 homeobox 1 |
Synonyms | OCT3,OCT4,Oct-4 |
Gene Type | protein-coding |
Organism | Sus scrofa(pig) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_021097869.1 | XP_020953528.1 | POU domain, class 5, transcription factor 1 isoform X1 |
NM_001113060.1 | NP_001106531.1 | POU domain, class 5, transcription factor 1 |
Activin-SMAD signaling is required for maintenance of porcine iPS cell self-renewal through upregulation of NANOG and OCT4 expression.
Yang F, Wang N, Wang Y, Yu T, Wang H
Journal of cellular physiology232(8)2253-2262(2017 Aug)
Identification of a novel 12-bp insertion/deletion (indel) of iPS-related Oct4 gene and its association with reproductive traits in male piglets.
Ren F, Yu S, Chen R, Lv X, Pan C
Animal reproduction science17855-60(2017 Mar)
OCT-4 expression is essential for the segregation of trophectoderm lineages in porcine preimplantation embryos.
Emura N, Sakurai N, Takahashi K, Hashizume T, Sawai K
The Journal of reproduction and development62(4)401-8(2016 Aug)
Overexpression of Oct4 in porcine ovarian stem/stromal cells enhances differentiation of oocyte-like cells in vitro and ovarian follicular formation in vivo.
Lee YM, Kim TH, Lee JH, Lee WJ, Jeon RH, Jang SJ, Ock SA, Lee SL, Park BW, Rho GJ
Journal of ovarian research924(2016 Apr)
Cdx2 represses Oct4 function via inducing its proteasome-dependent degradation in early porcine embryos.
Bou G, Liu S, Guo J, Zhao Y, Sun M, Xue B, Wang J, Wei Y, Kong Q, Liu Z
Developmental biology410(1)36-44(2016 Feb)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Activin A and overexpression of SMAD2/3 significantly promoted expressions of porcine NANOG and OCT4,maintaining induced pluripotent stem cell self-renewal through up-regulation of Nanog/OCT4 expression.
Title: Activin-SMAD signaling is required for maintenance of porcine iPS cell self-renewal through upregulation of NANOG and OCT4 expression.
These findings suggest that the 12-bp indel polymorphism of the Oct4 gene might be a potential DNA marker for selecting preferred individuals in relation to reproductive traits in pig marker-assisted selection breeding.
Title: Identification of a novel 12-bp insertion/deletion (indel) of iPS-related Oct4 gene and its association with reproductive traits in male piglets.
Our results indicate that continuous expression of OCT-4 in blastomeres is essential for trophectoderm formation of porcine embryos.
Title: OCT-4 expression is essential for the segregation of trophectoderm lineages in porcine preimplantation embryos.
Oct4-overexpression enhances porcine ovarian stem cell differentiation in to oocyte-like cells.
Title: Overexpression of Oct4 in porcine ovarian stem/stromal cells enhances differentiation of oocyte-like cells in vitro and ovarian follicular formation in vivo.
showed novel molecular regulation of CDX2 on Oct4, and provided important clues for clarifying the mechanism of interaction between CDX2 and Oct4 in embryo of mammals other than mouse
Title: Cdx2 represses Oct4 function via inducing its proteasome-dependent degradation in early porcine embryos.
The following POU5F1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the POU5F1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSe00789 | |
Clone ID Related Accession (Same CDS sequence) | NM_001113060.1 | |
Accession Version | NM_001113060.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1083bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-11-14 | |
Organism | Sus scrofa(pig) | |
Product | POU domain, class 5, transcription factor 1 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AJ251914.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA3180008, SAMN01915393 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGCGGGAC ACCTGGCTTC CGACTTCGCC TTCTCGCCCC CGCCGGGCGG TGGAGGCGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001106531.1 |
CDS | 1..1083 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001113060.1 |
1 | ATGGCGGGAC ACCTGGCTTC CGACTTCGCC TTCTCGCCCC CGCCGGGCGG TGGAGGCGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OSe222258 | |
Clone ID Related Accession (Same CDS sequence) | XM_021097869.1 | |
Accession Version | XM_021097869.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1086bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-05-12 | |
Organism | Sus scrofa(pig) | |
Product | POU domain, class 5, transcription factor 1 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_010449.5) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Sus scrofa Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCGGGAC ACCTGGCTTC CGACTTCGCC TTCTCGCCCC CGCCGGGCGG TGGAGGCGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_020953528.1 |
CDS | 92..1177 |
Translation |
Target ORF information:
Target ORF information:
|
XM_021097869.1 |
1 | ATGGCGGGAC ACCTGGCTTC CGACTTCGCC TTCTCGCCCC CGCCGGGCGG TGGAGGCGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Activin-SMAD signaling is required for maintenance of porcine iPS cell self-renewal through upregulation of NANOG and OCT4 expression. |
Identification of a novel 12-bp insertion/deletion (indel) of iPS-related Oct4 gene and its association with reproductive traits in male piglets. |
OCT-4 expression is essential for the segregation of trophectoderm lineages in porcine preimplantation embryos. |
Overexpression of Oct4 in porcine ovarian stem/stromal cells enhances differentiation of oocyte-like cells in vitro and ovarian follicular formation in vivo. |
Cdx2 represses Oct4 function via inducing its proteasome-dependent degradation in early porcine embryos. |