Gene Symbol | smc5 |
Entrez Gene ID | 2541587 |
Full Name | Smc5-6 complex SMC subunit Smc5 |
Gene Type | protein-coding |
Organism | Schizosaccharomyces pombe(fission yeast) |
ORF » Species Summary » Schizosaccharomyces pombe » smc5 cDNA ORF clone
Gene Symbol | smc5 |
Entrez Gene ID | 2541587 |
Full Name | Smc5-6 complex SMC subunit Smc5 |
Gene Type | protein-coding |
Organism | Schizosaccharomyces pombe(fission yeast) |
mRNA | Protein | Name |
---|---|---|
NM_001020338.2 | NP_594907.2 | Smc5-6 complex SMC subunit Smc5 |
Rattus norvegicus (Norway rat) | Smc5 | NP_001099827.1 |
Danio rerio (zebrafish) | smc5 | NP_001180470.1 |
Drosophila melanogaster (fruit fly) | Smc5 | NP_996141.2 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP011623 | XP_320881.2 |
Homo sapiens (human) | SMC5 | NP_055925.2 |
Bos taurus (cattle) | SMC5 | XP_002689686.1 |
Arabidopsis thaliana (thale cress) | SMC5 | NP_197096.1 |
Xenopus tropicalis (tropical clawed frog) | smc5 | XP_004910829.1 |
Pan troglodytes (chimpanzee) | SMC5 | XP_520066.3 |
Mus musculus (house mouse) | Smc5 | NP_001239613.1 |
Kluyveromyces lactis | KLLA0F07997g | XP_455442.1 |
SMC5 | XP_001090492.2 | |
Canis lupus familiaris (dog) | SMC5 | XP_533529.3 |
Saccharomyces cerevisiae (baker's yeast) | SMC5 | NP_014608.1 |
Schizosaccharomyces pombe (fission yeast) | smc5 | NP_594907.2 |
Neurospora crassa | NCU09065 | XP_963793.1 |
Gallus gallus (chicken) | SMC5 | NP_001034424.1 |
Eremothecium gossypii | AGOS_AEL337C | NP_984523.2 |
Magnaporthe oryzae (rice blast fungus) | MGG_12590 | XP_003720930.1 |
Oryza sativa (rice) | Os05g0596600 | NP_001056521.1 |
The genome sequence of Schizosaccharomyces pombe.
Wood V, Gwilliam R, Rajandream MA, Lyne M, Lyne R, Stewart A, Sgouros J, Peat N, Hayles J, Baker S, Basham D, Bowman S, Brooks K, Brown D, Brown S, Chillingworth T, Churcher C, Collins M, Connor R, Cronin A, Davis P, Feltwell T, Fraser A, Gentles S, Goble A, Hamlin N, Harris D, Hidalgo J, Hodgson G, Holroyd S, Hornsby T, Howarth S, Huckle EJ, Hunt S, Jagels K, James K, Jones L, Jones M, Leather S, McDonald S, McLean J, Mooney P, Moule S, Mungall K, Murphy L, Niblett D, Odell C, Oliver K, O'Neil S, Pearson D, Quail MA, Rabbinowitsch E, Rutherford K, Rutter S, Saunders D, Seeger K, Sharp S, Skelton J, Simmonds M, Squares R, Squares S, Stevens K, Taylor K, Taylor RG, Tivey A, Walsh S, Warren T, Whitehead S, Woodward J, Volckaert G, Aert R, Robben J, Grymonprez B, Weltjens I, Vanstreels E, Rieger M, Sch?fer M, M?ller-Auer S, Gabel C, Fuchs M, D?sterh?ft A, Fritzc C, Holzer E, Moestl D, Hilbert H, Borzym K, Langer I, Beck A, Lehrach H, Reinhardt R, Pohl TM, Eger P, Zimmermann W, Wedler H, Wambutt R, Purnelle B, Goffeau A, Cadieu E, Dr?ano S, Gloux S, Lelaure V, Mottier S, Galibert F, Aves SJ, Xiang Z, Hunt C, Moore K, Hurst SM, Lucas M, Rochet M, Gaillardin C, Tallada VA, Garzon A, Thode G, Daga RR, Cruzado L, Jimenez J, S?nchez M, del Rey F, Benito J, Dom?nguez A, Revuelta JL, Moreno S, Armstrong J, Forsburg SL, Cerutti L, Lowe T, McCombie WR, Paulsen I, Potashkin J, Shpakovski GV, Ussery D, Barrell BG, Nurse P, Cerrutti L
Nature415(6874)871-80(2002 Feb)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The function of the SMC5/6 complex and its mammalian homologs in the cell cycle has not been clarified yet.
Title: The (elusive) role of the SMC5/6 complex.
Smc6 contributes to DNA repair in vivo by targeting the Smc5-6 complex to single-stranded DNA substrates created during the processes of homologous recombination and/or DNA replication.
Title: DNA-binding properties of Smc6, a core component of the Smc5-6 DNA repair complex.
Smc5 is a required for homologous recombination in S. pombe.
Title: Nse1-dependent recruitment of Smc5/6 to lesion-containing loci contributes to the repair defects of mutant complexes.
In an examination of the evolutionary conservation of the Nse3-Nse4 interactions, we find that several MAGE proteins can interact with at least one of the NSE4/EID proteins.
Title: Interactions between the Nse3 and Nse4 components of the SMC5-6 complex identify evolutionarily conserved interactions between MAGE and EID Families.
Data show that defective cohesin removal is a major determinant of the mitotic lethality of Smc5-Smc6 mutants.
Title: Smc5-Smc6-dependent removal of cohesin from mitotic chromosomes.
The following smc5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the smc5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSc102118 | |
Clone ID Related Accession (Same CDS sequence) | NM_001020338.2 | |
Accession Version | NM_001020338.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3231bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-04-02 | |
Organism | Schizosaccharomyces pombe(fission yeast) | |
Product | Smc5-6 complex SMC subunit Smc5 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. This record is derived from an annotated genomic sequence (NC_003424). On Dec 10, 2012 this sequence version replaced NM_001020338.1. |
1 | ATGGATGGCC TTAGGCCTTC GAAACGAAGA AAAAGTAATC CTTTGTATTC AGATTACGCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_594907.2 |
CDS | 507..3737 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001020338.2 |
1 | ATGGATGGCC TTAGGCCTTC GAAACGAAGA AAAAGTAATC CTTTGTATTC AGATTACGCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The genome sequence of Schizosaccharomyces pombe. |