Gene Symbol | hmg1 |
Entrez Gene ID | 2538999 |
Full Name | 3-hydroxy-3-methylglutaryl-CoA reductase Hmg1 |
Gene Type | protein-coding |
Organism | Schizosaccharomyces pombe(fission yeast) |
ORF » Species Summary » Schizosaccharomyces pombe » hmg1 cDNA ORF clone
Gene Symbol | hmg1 |
Entrez Gene ID | 2538999 |
Full Name | 3-hydroxy-3-methylglutaryl-CoA reductase Hmg1 |
Gene Type | protein-coding |
Organism | Schizosaccharomyces pombe(fission yeast) |
mRNA | Protein | Name |
---|---|---|
NM_001023225.2 | NP_588235.1 | 3-hydroxy-3-methylglutaryl-CoA reductase Hmg1 |
Homo sapiens (human) | HMGCR | NP_000850.1 |
Gallus gallus (chicken) | HMGCR | NP_989816.1 |
Caenorhabditis elegans (roundworm) | hmgr-1 | NP_498626.2 |
Saccharomyces cerevisiae (baker's yeast) | HMG2 | NP_013555.1 |
Kluyveromyces lactis | KLLA0B04642g | XP_451740.1 |
Pan troglodytes (chimpanzee) | HMGCR | XP_001148405.2 |
Bos taurus (cattle) | HMGCR | NP_001099083.1 |
Xenopus tropicalis (tropical clawed frog) | hmgcr | XP_004910453.1 |
HMGCR | XP_002804463.1 | |
Canis lupus familiaris (dog) | HMGCR | XP_536323.3 |
Drosophila melanogaster (fruit fly) | Hmgcr | NP_732900.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_08975 | XP_003714014.1 |
Neurospora crassa | NCU00712 | XP_964546.1 |
Arabidopsis thaliana (thale cress) | HMG1 | NP_177775.2 |
Oryza sativa (rice) | Os09g0492700 | NP_001063541.1 |
Oryza sativa (rice) | Os08g0512700 | NP_001062221.1 |
Mus musculus (house mouse) | Hmgcr | NP_032281.2 |
Rattus norvegicus (Norway rat) | Hmgcr | NP_037266.2 |
Danio rerio (zebrafish) | hmgcra | NP_001073446.1 |
Arabidopsis thaliana (thale cress) | HMG2 | NP_179329.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP002288 | XP_307890.5 |
Saccharomyces cerevisiae (baker's yeast) | HMG1 | NP_013636.1 |
Eremothecium gossypii | AGOS_AER152W | NP_985010.2 |
Schizosaccharomyces pombe (fission yeast) | hmg1 | NP_588235.1 |
The genome sequence of Schizosaccharomyces pombe.
Wood V, Gwilliam R, Rajandream MA, Lyne M, Lyne R, Stewart A, Sgouros J, Peat N, Hayles J, Baker S, Basham D, Bowman S, Brooks K, Brown D, Brown S, Chillingworth T, Churcher C, Collins M, Connor R, Cronin A, Davis P, Feltwell T, Fraser A, Gentles S, Goble A, Hamlin N, Harris D, Hidalgo J, Hodgson G, Holroyd S, Hornsby T, Howarth S, Huckle EJ, Hunt S, Jagels K, James K, Jones L, Jones M, Leather S, McDonald S, McLean J, Mooney P, Moule S, Mungall K, Murphy L, Niblett D, Odell C, Oliver K, O'Neil S, Pearson D, Quail MA, Rabbinowitsch E, Rutherford K, Rutter S, Saunders D, Seeger K, Sharp S, Skelton J, Simmonds M, Squares R, Squares S, Stevens K, Taylor K, Taylor RG, Tivey A, Walsh S, Warren T, Whitehead S, Woodward J, Volckaert G, Aert R, Robben J, Grymonprez B, Weltjens I, Vanstreels E, Rieger M, Sch?fer M, M?ller-Auer S, Gabel C, Fuchs M, D?sterh?ft A, Fritzc C, Holzer E, Moestl D, Hilbert H, Borzym K, Langer I, Beck A, Lehrach H, Reinhardt R, Pohl TM, Eger P, Zimmermann W, Wedler H, Wambutt R, Purnelle B, Goffeau A, Cadieu E, Dr?ano S, Gloux S, Lelaure V, Mottier S, Galibert F, Aves SJ, Xiang Z, Hunt C, Moore K, Hurst SM, Lucas M, Rochet M, Gaillardin C, Tallada VA, Garzon A, Thode G, Daga RR, Cruzado L, Jimenez J, S?nchez M, del Rey F, Benito J, Dom?nguez A, Revuelta JL, Moreno S, Armstrong J, Forsburg SL, Cerutti L, Lowe T, McCombie WR, Paulsen I, Potashkin J, Shpakovski GV, Ussery D, Barrell BG, Nurse P, Cerrutti L
Nature415(6874)871-80(2002 Feb)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
This is the first demonstration of clear phenotypes arising from a nonsense mutation of an essential gene, HMG1, in fission yeast.
Title: Pleiotropic phenotypes caused by an opal nonsense mutation in an essential gene encoding HMG-CoA reductase in fission yeast.
Intracellular Signaling Peptides and Proteins dependent regulation of 3-hydroxy-3-methylglutaryl-CoA reductase activity functions through the phosphorylation of S1024 and T1028.
Title: Insig regulates HMG-CoA reductase by controlling enzyme phosphorylation in fission yeast.
The following hmg1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the hmg1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSc99289 | |
Clone ID Related Accession (Same CDS sequence) | NM_001023225.2 | |
Accession Version | NM_001023225.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3162bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-04-02 | |
Organism | Schizosaccharomyces pombe(fission yeast) | |
Product | 3-hydroxy-3-methylglutaryl-CoA reductase Hmg1 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. This record is derived from an annotated genomic sequence (NC_003421). On Dec 10, 2012 this sequence version replaced NM_001023225.1. |
1 | ATGATTTATA AACTTGCTGC TCGGTATCCA ATTCAAGTGA TTGCCATTGT GGGCATCCTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_588235.1 |
CDS | 803..3964 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001023225.2 |
1 | ATGATTTATA AACTTGCTGC TCGGTATCCA ATTCAAGTGA TTGCCATTGT GGGCATCCTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The genome sequence of Schizosaccharomyces pombe. |