Gene Symbol | GRX4 |
Entrez Gene ID | 856921 |
Full Name | monothiol glutaredoxin GRX4 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » GRX4 cDNA ORF clone
Gene Symbol | GRX4 |
Entrez Gene ID | 856921 |
Full Name | monothiol glutaredoxin GRX4 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001179064.3 | NP_011101.3 | monothiol glutaredoxin GRX4 |
Homo sapiens (human) | GLRX3 | NP_006532.2 |
Mus musculus (house mouse) | Glrx3 | NP_075629.2 |
Oryza sativa (rice) | Os10g0500700 | NP_001064982.1 |
Xenopus tropicalis (tropical clawed frog) | glrx3 | NP_001017209.1 |
Pan troglodytes (chimpanzee) | GLRX3 | XP_508113.2 |
Canis lupus familiaris (dog) | GLRX3 | XP_535061.2 |
Caenorhabditis elegans (roundworm) | glrx-3 | NP_001023756.1 |
GLRX3 | XP_001090479.1 | |
Bos taurus (cattle) | GLRX3 | NP_001030273.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_06356 | XP_003717224.1 |
Rattus norvegicus (Norway rat) | Glrx3 | NP_116003.2 |
Gallus gallus (chicken) | GLRX3 | NP_001264313.1 |
Saccharomyces cerevisiae (baker's yeast) | GRX4 | NP_011101.3 |
Schizosaccharomyces pombe (fission yeast) | grx4 | NP_596647.1 |
Neurospora crassa | NCU09803 | XP_964063.1 |
Danio rerio (zebrafish) | glrx3 | NP_001005950.1 |
Saccharomyces cerevisiae (baker's yeast) | GRX3 | NP_010383.3 |
Kluyveromyces lactis | KLLA0C17842g | XP_452997.1 |
Eremothecium gossypii | AGOS_AGR111W | NP_986777.1 |
Arabidopsis thaliana (thale cress) | AT4G04950 | NP_192404.1 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome V.
Dietrich FS, Mulligan J, Hennessy K, Yelton MA, Allen E, Araujo R, Aviles E, Berno A, Brennan T, Carpenter J, Chen E, Cherry JM, Chung E, Duncan M, Guzman E, Hartzell G, Hunicke-Smith S, Hyman RW, Kayser A, Komp C, Lashkari D, Lew H, Lin D, Mosedale D, Davis RW
Nature387(6632 Suppl)78-81(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
RNR cofactor biogenesis requires the ISC machinery to mature the Grx3/4 and Dre2 Fe-S proteins, which then function in iron and electron delivery to RNR, respectively.
Title: The diferric-tyrosyl radical cluster of ribonucleotide reductase and cytosolic iron-sulfur clusters have distinct and similar biogenesis requirements.
Slt2 form iron/sulphur bridged clusters with Grx3 and Grx4.
Title: Physical interaction between the MAPK Slt2 of the PKC1-MAPK pathway and Grx3/Grx4 glutaredoxins is required for the oxidative stress response in budding yeast.
We provide new mechanistic insights into Grx3/4 regulation of Sir2 by S-deglutathionylation to increase cell resistance to stress. This finding offers news perspectives on monothiol Grxs in redox signaling, describing Sir2 as a physiological substrate regulated by S-glutathionylation.
Title: Reversible glutathionylation of Sir2 by monothiol glutaredoxins Grx3/4 regulates stress resistance.
diferric tyrosyl radical formation in Saccharomyces cerevisiae Rnr2 protein: requirement of Rnr4 and contribution of Grx3/4 AND Dre2 proteins.(
Title: Investigation of in vivo diferric tyrosyl radical formation in Saccharomyces cerevisiae Rnr2 protein: requirement of Rnr4 and contribution of Grx3/4 AND Dre2 proteins.
The authors present data showing that both Grx3 and Grx4 have roles in actin cytoskeleton remodeling and in cellular defenses against oxidative stress caused by reactive oxygen species (ROS) accumulation.
Title: Glutaredoxins Grx4 and Grx3 of Saccharomyces cerevisiae play a role in actin dynamics through their Trx domains, which contributes to oxidative stress resistance.
The following GRX4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GRX4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi05669 | |
Clone ID Related Accession (Same CDS sequence) | NM_001179064.3 | |
Accession Version | NM_001179064.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 735bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | monothiol glutaredoxin GRX4 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001137). On Jul 30, 2012 this sequence version replaced NM_001179064.2. ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGACTGTGG TTGAAATAAA AAGCCAGGAC CAATTTACGC AACTAACCAC TACAAACGCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_011101.3 |
CDS | 1..735 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001179064.3 |
1 | ATGACTGTGG TTGAAATAAA AAGCCAGGAC CAATTTACGC AACTAACCAC TACAAACGCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome V. |
Life with 6000 genes. |