Gene Symbol | YEN1 |
Entrez Gene ID | 856764 |
Full Name | crossover junction endodeoxyribonuclease |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » YEN1 cDNA ORF clone
Gene Symbol | YEN1 |
Entrez Gene ID | 856764 |
Full Name | crossover junction endodeoxyribonuclease |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001178932.2 | NP_010959.2 | crossover junction endodeoxyribonuclease |
Eremothecium gossypii | AGOS_AFR238W | NP_985785.1 |
Saccharomyces cerevisiae (baker's yeast) | YEN1 | NP_010959.2 |
Kluyveromyces lactis | KLLA0A01320g | XP_451057.1 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome V.
Dietrich FS, Mulligan J, Hennessy K, Yelton MA, Allen E, Araujo R, Aviles E, Berno A, Brennan T, Carpenter J, Chen E, Cherry JM, Chung E, Duncan M, Guzman E, Hartzell G, Hunicke-Smith S, Hyman RW, Kayser A, Komp C, Lashkari D, Lew H, Lin D, Mosedale D, Davis RW
Nature387(6632 Suppl)78-81(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Unresolved recombination intermediates are a source of mitotic sister chromatid bridges, and Mus81-Mms4 and Yen1 play a central role in their resolution in vivo.
Title: Mus81-Mms4 and Yen1 resolve a novel anaphase bridge formed by noncanonical Holliday junctions.
Have refined the substrate specificity of budding yeast Cdc14 and, using this insight, identified the Holliday junction resolvase Yen1 as a DNA repair target of Cdc14.
Title: The Cdk/cDc14 module controls activation of the Yen1 holliday junction resolvase to promote genome stability.
Master cell-cycle regulators, cyclin-dependent kinase (Cdk) and Cdc14 phosphatase, control the actions of Yen1 during mitosis.
Title: Dual control of Yen1 nuclease activity and cellular localization by Cdk and Cdc14 prevents genome instability.
The Yen1 serves a backup function responsible for resolving intermediates in mus81Delta mutants, or when conversion tracts are short.
Title: Mus81 and Yen1 promote reciprocal exchange during mitotic recombination to maintain genome integrity in budding yeast.
Yen1 has a role in the response to DNA damage; HJ resolution functions of Yen1 overlap with Mus81 during replication fork repair
Title: Overlapping roles for Yen1 and Mus81 in cellular Holliday junction processing.
The following YEN1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the YEN1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi05531 | |
Clone ID Related Accession (Same CDS sequence) | NM_001178932.2 | |
Accession Version | NM_001178932.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2280bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | crossover junction endodeoxyribonuclease | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001137). On Apr 26, 2011 this sequence version replaced NM_001178932.1. ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGGGTGTCT CACAAATATG GGAATTTTTG AAGCCATATC TGCAAGATTC CAGAATTCCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_010959.2 |
CDS | 1..2280 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001178932.2 |
1 | ATGGGTGTCT CACAAATATG GGAATTTTTG AAGCCATATC TGCAAGATTC CAGAATTCCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome V. |
Life with 6000 genes. |