Gene Symbol | DSK2 |
Entrez Gene ID | 855319 |
Full Name | Dsk2p |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » DSK2 cDNA ORF clone
Gene Symbol | DSK2 |
Entrez Gene ID | 855319 |
Full Name | Dsk2p |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001182783.1 | NP_014003.1 | Dsk2p |
Saccharomyces cerevisiae (baker's yeast) | DSK2 | NP_014003.1 |
Eremothecium gossypii | AGOS_ABL129W | NP_982818.1 |
Neurospora crassa | NCU03028 | XP_965414.2 |
Kluyveromyces lactis | KLLA0D01859g | XP_453150.1 |
Schizosaccharomyces pombe (fission yeast) | dph1 | NP_594159.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_01318 | XP_003714243.1 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII.
Bowman S, Churcher C, Badcock K, Brown D, Chillingworth T, Connor R, Dedman K, Devlin K, Gentles S, Hamlin N, Hunt S, Jagels K, Lye G, Moule S, Odell C, Pearson D, Rajandream M, Rice P, Skelton J, Walsh S, Whitehead S, Barrell B
Nature387(6632 Suppl)90-3(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Proteasome/autophagy pathway choice is independent of the ubiquitin-binding properties of the receptors Dsk2/Cue5 but largely determined by their oligomerization potentials.
Title: Receptor oligomerization guides pathway choice between proteasomal and autophagic degradation.
Identify the Cdc48-Rad23/Dsk2 axis as a major route to the proteasome.
Title: In?Vivo Ubiquitin Linkage-type Analysis Reveals that the Cdc48-Rad23/Dsk2 Axis Contributes to K48-Linked Chain Specificity of the Proteasome.
functional yeast proteasomes have the capacity to associate and dissociate with Rpn10 and that Rpn10 monoubiquitination decreases the Rpn10-proteasome and Rpn10-Dsk2 associations.
Title: Rpn10 monoubiquitination orchestrates the association of the ubiquilin-type DSK2 receptor with the proteasome.
These results indicate that ubiquitination in the UBL domain of Dsk2 has in vivo functions in the ubiquitin-proteasome pathway in yeast.
Title: Ubiquitin chains in the Dsk2 UBL domain mediate Dsk2 stability and protein degradation in yeast.
C-terminal UBA domain of Dsk2 ubiquitin receptor protects it by preventing initiation of protein degradation at the proteasome.
Title: C-terminal UBA domains protect ubiquitin receptors by preventing initiation of protein degradation.
The following DSK2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the DSK2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi04269 | |
Clone ID Related Accession (Same CDS sequence) | NM_001182783.1 | |
Accession Version | NM_001182783.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1122bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | Dsk2p | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001145). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGTCGTTGA ATATACATAT CAAGTCAGGA CAAGACAAGT GGGAAGTAAA TGTGGCACCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_014003.1 |
CDS | 1..1122 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001182783.1 |
1 | ATGTCGTTGA ATATACATAT CAAGTCAGGA CAAGACAAGT GGGAAGTAAA TGTGGCACCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII. |
Life with 6000 genes. |