RNT1 cDNA ORF clone, Saccharomyces cerevisiae S288C

The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII.
Bowman S, Churcher C, Badcock K, Brown D, Chillingworth T, Connor R, Dedman K, Devlin K, Gentles S, Hamlin N, Hunt S, Jagels K, Lye G, Moule S, Odell C, Pearson D, Rajandream M, Rice P, Skelton J, Walsh S, Whitehead S, Barrell B
Nature387(6632 Suppl)90-3(1997 May)

Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)

The functional cycle of eukaryotic Rnt1p includes five consecutive steps of double-stranded RNA processing.
Title: The Functional Cycle of Rnt1p: Five Consecutive Steps of Double-Stranded RNA Processing by a Eukaryotic RNase III.

Data indicate that mutant of the RNA processing machinery (RNT1), and RNA/DNA helicase SEN1 mutants that are unable to interact with Rnt1p, exhibit a flocculation phenotype.
Title: Flocculation in Saccharomyces cerevisiae is regulated by RNA/DNA helicase Sen1p.

the data suggest that Rnt1p reactivity is triggered by malleable RNA degradation signals that permit dynamic response to changes in growth conditions
Title: Transcriptome wide annotation of eukaryotic RNase III reactivity and degradation signals.

The double stranded RNA binding domain and N-terminal domains of Rnt1p function as two rulers that measure the distance between the tetraloop and the cleavage site.
Title: Structure of a eukaryotic RNase III postcleavage complex reveals a double-ruler mechanism for substrate selection.

The Rnt1p double-stranded RNA binding domain has an extended hydrophobic core comprising helix alpha1, the alpha1-beta1 loop, and helix alpha3.
Title: Intrinsic dynamics of an extended hydrophobic core in the S. cerevisiae RNase III dsRBD contributes to recognition of specific RNA binding sites.