Gene Symbol | CTF18 |
Entrez Gene ID | 855102 |
Full Name | Ctf18p |
Synonyms | CHL12 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » CTF18 cDNA ORF clone
Gene Symbol | CTF18 |
Entrez Gene ID | 855102 |
Full Name | Ctf18p |
Synonyms | CHL12 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001182577.1 | NP_013795.1 | Ctf18p |
Eremothecium gossypii | AGOS_ABR019C | NP_982965.1 |
Kluyveromyces lactis | KLLA0B13739g | XP_452142.1 |
Schizosaccharomyces pombe (fission yeast) | ctf18 | NP_595200.1 |
Saccharomyces cerevisiae (baker's yeast) | CTF18 | NP_013795.1 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII.
Bowman S, Churcher C, Badcock K, Brown D, Chillingworth T, Connor R, Dedman K, Devlin K, Gentles S, Hamlin N, Hunt S, Jagels K, Lye G, Moule S, Odell C, Pearson D, Rajandream M, Rice P, Skelton J, Walsh S, Whitehead S, Barrell B
Nature387(6632 Suppl)90-3(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
These results indicate that the Ctf18-RFC/Polepsilon interaction plays a crucial role in maintaining genome stability in budding yeast, probably through recruitment of this PCNA loader to the replication fork.
Title: Conserved interaction of Ctf18-RFC with DNA polymerase ? is critical for maintenance of genome stability in Saccharomyces cerevisiae.
The findings indicate that the association of Ctf18-RFC with Pol at defective replication forks is a key step in activation of the S-phase checkpoint.
Title: A conserved Pol? binding module in Ctf18-RFC is required for S-phase checkpoint activation downstream of Mec1.
Ctf18 confers protection against stalling or breaks at the replication fork in cells that either lack, or are compromised for, telomerase activity, which is likely to contribute another level to telomere size homeostasis.
Title: The Ctf18RFC clamp loader is essential for telomere stability in telomerase-negative and mre11 mutant alleles.
Results suggest that Elg1, Ctf4, and Ctf18 may coordinate the relative movement of the replication fork with respect to the cohesin ring.
Title: The ELG1 clamp loader plays a role in sister chromatid cohesion.
During chromatid cohesion establishment, Ctf18 is found at the DNA replication fork.
Title: Establishment of sister chromatid cohesion at the S. cerevisiae replication fork.
The following CTF18 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CTF18 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi04076 | |
Clone ID Related Accession (Same CDS sequence) | NM_001182577.1 | |
Accession Version | NM_001182577.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2226bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | Ctf18p | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001145). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGGTTGATA CCGCACCATA CATTGGTTCA CTAGGGAGAA GTTCCCTTTT TGATACTGGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_013795.1 |
CDS | 1..2226 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001182577.1 |
1 | ATGGTTGATA CCGCACCATA CATTGGTTCA CTAGGGAGAA GTTCCCTTTT TGATACTGGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII. |
Life with 6000 genes. |