Gene Symbol | MLC1 |
Entrez Gene ID | 852772 |
Full Name | Mlc1p |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » MLC1 cDNA ORF clone
Gene Symbol | MLC1 |
Entrez Gene ID | 852772 |
Full Name | Mlc1p |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001180971.1 | NP_011409.1 | Mlc1p |
Rattus norvegicus (Norway rat) | Myl1 | NP_001071124.1 |
Pan troglodytes (chimpanzee) | MYL1 | XP_516064.2 |
Canis lupus familiaris (dog) | MYL1 | XP_005640670.1 |
Mus musculus (house mouse) | Myl1 | NP_067260.1 |
Homo sapiens (human) | MYL1 | NP_524144.1 |
Bos taurus (cattle) | MYL1 | NP_001073046.1 |
Danio rerio (zebrafish) | myl1 | NP_956294.1 |
Kluyveromyces lactis | KLLA0F10439g | XP_455555.1 |
Schizosaccharomyces pombe (fission yeast) | cdc4 | NP_594947.1 |
Neurospora crassa | NCU06617 | XP_962359.2 |
Danio rerio (zebrafish) | mylz3 | NP_571694.1 |
Saccharomyces cerevisiae (baker's yeast) | MLC1 | NP_011409.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_09470 | XP_003712281.1 |
Gallus gallus (chicken) | MYL1 | NP_001038097.1 |
Eremothecium gossypii | AGOS_AFL030C | NP_985518.1 |
Xenopus tropicalis (tropical clawed frog) | myl1 | NP_988954.1 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome VII.
Tettelin H, Agostoni Carbone ML, Albermann K, Albers M, Arroyo J, Backes U, Barreiros T, Bertani I, Bjourson AJ, Br?ckner M, Bruschi CV, Carignani G, Castagnoli L, Cerdan E, Clemente ML, Coblenz A, Coglievina M, Coissac E, Defoor E, Del Bino S, Delius H, Delneri D, de Wergifosse P, Dujon B, Kleine K
Nature387(6632 Suppl)81-4(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Myo1 plays a major role in the septin-dependent Mlc1 localization to the division site before cytokinesis, whereas the formin Bni1 plays a major role in the actin filament-dependent Mlc1 localization during cytokinesis.
Title: Myosin?II heavy chain and formin mediate the targeting of myosin essential light chain to the division site before and during cytokinesis.
Here, we show that the rigid conformation of the loop connecting the two EF-hand motifs of the Mlc1p N-lobe explains its differential ability to interact with myosin V IQ1.
Title: N-lobe dynamics of myosin light chain dictates its mode of interaction with myosin V IQ1.
myosin light chain 1 (Mlc1p), required for vesicle delivery at the mother-bud neck during cytokinesis, binds to the Myo2p GTD in a region overlapping that of Ypt32p.
Title: Ypt32p and Mlc1p bind within the vesicle binding region of the class V myosin Myo2p globular tail domain.
analysis of the interaction of Mlc1p with the first IQ motif of Myo2p
Title: Structural basis for the interaction of the myosin light chain Mlc1p with the myosin V Myo2p IQ motifs.
Mlc1p/Myo2p interaction is stimulated by a signal that requires Sec2p and activation of Ypt32p
Title: GTP drives myosin light chain 1 interaction with the class V myosin Myo2 IQ motifs via a Sec2 RabGEF-mediated pathway.
The following MLC1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MLC1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi02140 | |
Clone ID Related Accession (Same CDS sequence) | NM_001180971.1 | |
Accession Version | NM_001180971.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 450bp) Protein sequence SNP |
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Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | Mlc1p | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001139). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGTCAGCCA CCAGAGCCAA TAAAGATATT TTCACACTAT TCGACAAGAA GGGTCAAGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_011409.1 |
CDS | 1..450 |
Translation |
Target ORF information:
Target ORF information:
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1 | ATGTCAGCCA CCAGAGCCAA TAAAGATATT TTCACACTAT TCGACAAGAA GGGTCAAGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome VII. |
Life with 6000 genes. |