Gene Symbol | SEC18 |
Entrez Gene ID | 852372 |
Full Name | AAA family ATPase SEC18 |
Synonyms | ANU4 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » SEC18 cDNA ORF clone
Gene Symbol | SEC18 |
Entrez Gene ID | 852372 |
Full Name | AAA family ATPase SEC18 |
Synonyms | ANU4 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001178428.3 | NP_009636.3 | AAA family ATPase SEC18 |
Pan troglodytes (chimpanzee) | NSF | XP_511626.3 |
Canis lupus familiaris (dog) | NSF | XP_548044.2 |
Mus musculus (house mouse) | Nsf | NP_032766.2 |
Drosophila melanogaster (fruit fly) | comt | NP_001259506.1 |
Saccharomyces cerevisiae (baker's yeast) | SEC18 | NP_009636.3 |
Gallus gallus (chicken) | NSF | NP_001019627.1 |
Danio rerio (zebrafish) | nsfa | NP_001037793.1 |
Neurospora crassa | NCU03387 | XP_956834.1 |
Xenopus tropicalis (tropical clawed frog) | nsf | NP_001072788.1 |
Bos taurus (cattle) | NSF | XP_002696103.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP012684 | XP_307148.3 |
Schizosaccharomyces pombe (fission yeast) | sec18 | NP_594690.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_02418 | XP_003709204.1 |
NSF | XP_002800596.1 | |
Caenorhabditis elegans (roundworm) | nsf-1 | NP_001076603.1 |
Caenorhabditis elegans (roundworm) | nsf-1 | NP_001076604.1 |
Homo sapiens (human) | NSF | NP_006169.2 |
Rattus norvegicus (Norway rat) | Nsf | NP_068516.1 |
Drosophila melanogaster (fruit fly) | Nsf2 | NP_788676.1 |
Kluyveromyces lactis | KLLA0C14520g | XP_452850.1 |
Eremothecium gossypii | AGOS_AER169C | NP_985027.1 |
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
Complete DNA sequence of yeast chromosome II.
Feldmann H, Aigle M, Aljinovic G, Andr? B, Baclet MC, Barthe C, Baur A, B?cam AM, Biteau N, Boles E, Brandt T, Brendel M, Br?ckner M, Bussereau F, Christiansen C, Contreras R, Crouzet M, Cziepluch C, D?molis N, Delaveau T, Doignon F, Domdey H, D?sterhus S, Dubois E, Dujon B, El Bakkoury M, Entian KD, Feurmann M, Fiers W, Fobo GM, Fritz C, Gassenhuber H, Glandsdorff N, Goffeau A, Grivell LA, de Haan M, Hein C, Herbert CJ, Hollenberg CP, Holmstr?m K, Jacq C, Jacquet M, Jauniaux JC, Jonniaux JL, Kalles?e T, Kiesau P, Kirchrath L, K?tter P, Korol S, Liebl S, Logghe M, Lohan AJ, Louis EJ, Li ZY, Maat MJ, Mallet L, Mannhaupt G, Messenguy F, Miosga T, Molemans F, M?ller S, Nasr F, Obermaier B, Perea J, Pi?rard A, Piravandi E, Pohl FM, Pohl TM, Potier S, Proft M, Purnelle B, Ramezani Rad M, Rieger M, Rose M, Schaaff-Gerstenschl?ger I, Scherens B, Schwarzlose C, Skala J, Slonimski PP, Smits PH, Souciet JL, Steensma HY, Stucka R, Urrestarazu A, van der Aart QJ, van Dyck L, Vassarotti A, Vetter I, Vierendeels F, Vissers S, Wagner G, de Wergifosse P, Wolfe KH, Zagulski M, Zimmermann FK, Mewes HW, Kleine K
The EMBO journal13(24)5795-809(1994 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Sec17 binds to trans-SNARE complexes, oligomerizes, and inserts apolar loops into the apposed membranes, locally disturbing the lipid bilayer and lowering the energy barrier for fusion without Sec18
Title: Sec17 can trigger fusion of trans-SNARE paired membranes without Sec18.
In vitro, Sly1 and Vps33 impede SNARE complex disassembly by Sec18 and ATP
Title: SM proteins Sly1 and Vps33 co-assemble with Sec17 and SNARE complexes to oppose SNARE disassembly by Sec18.
Using a reconstituted proteoliposome fusion system, the authors show that trans-SNARE complex, like cis-SNARE complex, is sensitive to Sec17p/Sec18p mediated disassembly.
Title: HOPS prevents the disassembly of trans-SNARE complexes by Sec17p/Sec18p during membrane fusion.
Data show that the ternary synergy of phosphoinositides and 2 SNARE chaperone systems (SNARE Vam7p and Sec17p/Sec18p/ATP
Title: Phosphoinositides and SNARE chaperones synergistically assemble and remodel SNARE complexes for membrane fusion.
Data suggest that Sec18p and Vam7p remodel trans-SNARE complexes to permit a lipid-anchored R-SNARE to support yeast vacuole fusion.
Title: Sec18p and Vam7p remodel trans-SNARE complexes to permit a lipid-anchored R-SNARE to support yeast vacuole fusion.
The following SEC18 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SEC18 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi01787 | |
Clone ID Related Accession (Same CDS sequence) | NM_001178428.3 | |
Accession Version | NM_001178428.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2277bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | AAA family ATPase SEC18 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001134). On Jul 30, 2012 this sequence version replaced NM_001178428.2. ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGTTCAAGA TACCTGGTTT TGGAAAAGCT GCTGCAAATC ATACTCCACC AGATATGACA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_009636.3 |
CDS | 1..2277 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001178428.3 |
1 | ATGTTCAAGA TACCTGGTTT TGGAAAAGCT GCTGCAAATC ATACTCCACC AGATATGACA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Life with 6000 genes. |
Complete DNA sequence of yeast chromosome II. |