Gene Symbol | MUS81 |
Entrez Gene ID | 851994 |
Full Name | Mus81p |
Synonyms | SLX3 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » MUS81 cDNA ORF clone
Gene Symbol | MUS81 |
Entrez Gene ID | 851994 |
Full Name | Mus81p |
Synonyms | SLX3 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001180694.3 | NP_010674.3 | Mus81p |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP008836 | XP_319580.4 |
Pan troglodytes (chimpanzee) | MUS81 | XP_522066.4 |
MUS81 | XP_001112824.1 | |
Rattus norvegicus (Norway rat) | Mus81 | NP_001020816.1 |
Eremothecium gossypii | AGOS_AFR141C | NP_985688.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_04585 | XP_003713609.1 |
Xenopus tropicalis (tropical clawed frog) | mus81 | NP_001011004.1 |
Canis lupus familiaris (dog) | MUS81 | XP_533230.2 |
Mus musculus (house mouse) | Mus81 | NP_082153.3 |
Danio rerio (zebrafish) | mus81 | NP_998683.1 |
Schizosaccharomyces pombe (fission yeast) | mus81 | XP_001713161.1 |
Bos taurus (cattle) | MUS81 | NP_001039756.1 |
Drosophila melanogaster (fruit fly) | mus81 | NP_569873.1 |
Saccharomyces cerevisiae (baker's yeast) | MUS81 | NP_010674.3 |
Kluyveromyces lactis | KLLA0E03015g | XP_454081.1 |
Neurospora crassa | NCU07457 | XP_963908.1 |
Homo sapiens (human) | MUS81 | NP_079404.3 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome IV.
Jacq C, Alt-M?rbe J, Andre B, Arnold W, Bahr A, Ballesta JP, Bargues M, Baron L, Becker A, Biteau N, Bl?cker H, Blugeon C, Boskovic J, Brandt P, Br?ckner M, Buitrago MJ, Coster F, Delaveau T, del Rey F, Dujon B, Eide LG, Garcia-Cantalejo JM, Goffeau A, Gomez-Peris A, Zaccaria P
Nature387(6632 Suppl)75-8(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The scaffold protein Rtt107, which binds the Mus81-Mms4 complex, interacts with Cdc7 and thereby targets Cdc7-Dbf4 and Cdc5 to the complex enabling full Mus81 activation.
Title: Dbf4-dependent kinase and the Rtt107 scaffold promote Mus81-Mms4 resolvase activation during mitosis.
The data point to the possibility that the involvement of Esc2 in the metabolism of sister chromatid junctions is, in part, via modulation of the activity of the Mus81 complex.
Title: Esc2 promotes Mus81 complex-activity via its SUMO-like and DNA binding domains.
Our data suggest that Srs2 and Mus81-Mms4 have critical roles in preventing the formation of (or in resolving) toxic inter-homolog joint molecules, which could otherwise interfere with chromosome segregation and lead to genetic instability.
Title: Srs2 and Mus81-Mms4 Prevent Accumulation of Toxic Inter-Homolog Recombination Intermediates.
this study proposes that lack of a timely converging fork or Mus81 may propel genome instability observed in cancer.
Title: DNA REPAIR. Mus81 and converging forks limit the mutagenicity of replication fork breakage.
data point to a coordinated role of Mus81-Mms4 and Srs2 in processing of recombination as well as replication intermediates
Title: Srs2 promotes Mus81-Mms4-mediated resolution of recombination intermediates.
The following MUS81 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MUS81 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi01466 | |
Clone ID Related Accession (Same CDS sequence) | NM_001180694.3 | |
Accession Version | NM_001180694.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1899bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | Mus81p | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001136). On Jul 30, 2012 this sequence version replaced NM_001180694.2. ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGGAACTCT CATCAAACTT AAAAGACCTA TATATTGAAT GGTTACAAGA ATTAGTTGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_010674.3 |
CDS | 1..1899 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001180694.3 |
1 | ATGGAACTCT CATCAAACTT AAAAGACCTA TATATTGAAT GGTTACAAGA ATTAGTTGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome IV. |
Life with 6000 genes. |