Gene Symbol | CWC2 |
Entrez Gene ID | 851318 |
Full Name | Cwc2p |
Synonyms | NTC40 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » CWC2 cDNA ORF clone
Gene Symbol | CWC2 |
Entrez Gene ID | 851318 |
Full Name | Cwc2p |
Synonyms | NTC40 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001180269.1 | NP_010072.1 | Cwc2p |
Kluyveromyces lactis | KLLA0C15411g | XP_452889.1 |
Saccharomyces cerevisiae (baker's yeast) | CWC2 | NP_010072.1 |
Schizosaccharomyces pombe (fission yeast) | cwf2 | NP_593337.1 |
Eremothecium gossypii | AGOS_AFR451WA | XP_002999494.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_08641 | XP_003711071.1 |
Neurospora crassa | NCU01184 | XP_961550.1 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome IV.
Jacq C, Alt-M?rbe J, Andre B, Arnold W, Bahr A, Ballesta JP, Bargues M, Baron L, Becker A, Biteau N, Bl?cker H, Blugeon C, Boskovic J, Brandt P, Br?ckner M, Buitrago MJ, Coster F, Delaveau T, del Rey F, Dujon B, Eide LG, Garcia-Cantalejo JM, Goffeau A, Gomez-Peris A, Zaccaria P
Nature387(6632 Suppl)75-8(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The study found that one function of Cwc2 is to stabilize U2-U6 snRNA helix I during splicing.
Title: Remodeling of U2-U6 snRNA helix I during pre-mRNA splicing by Prp16 and the NineTeen Complex protein Cwc2.
The S. cerevisiae Cwc2 protein functions prior to step 1 of splicing.
Title: Cwc2 and its human homologue RBM22 promote an active conformation of the spliceosome catalytic centre.
we report the 1.9 A (1 A=0.1 nm) X-ray structure of the Cwc2 core domain, which is both necessary and sufficient for RNA binding.
Title: Structure of the mRNA splicing complex component Cwc2: insights into RNA recognition.
Yeast cells depleted of Cwc2 accumulate pre-mRNA and display reduced levels of U1, U4, U5 and U6 snRNAs.
Title: The RNA binding protein Cwc2 interacts directly with the U6 snRNA to link the nineteen complex to the spliceosome during pre-mRNA splicing.
The following CWC2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CWC2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi00881 | |
Clone ID Related Accession (Same CDS sequence) | NM_001180269.1 | |
Accession Version | NM_001180269.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1020bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | Cwc2p | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001136). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGACATCTT GGAGGGATAA ATCCGCGAAA GTGCAAGTGA AGGAGTCAGA ACTGCCCTCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_010072.1 |
CDS | 1..1020 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001180269.1 |
1 | ATGACATCTT GGAGGGATAA ATCCGCGAAA GTGCAAGTGA AGGAGTCAGA ACTGCCCTCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome IV. |
Life with 6000 genes. |