TFS1 cDNA ORF clone, Saccharomyces cerevisiae S288C

The nucleotide sequence of Saccharomyces cerevisiae chromosome XII.
Johnston M, Hillier L, Riles L, Albermann K, Andr? B, Ansorge W, Benes V, Br?ckner M, Delius H, Dubois E, D?sterh?ft A, Entian KD, Floeth M, Goffeau A, Hebling U, Heumann K, Heuss-Neitzel D, Hilbert H, Hilger F, Kleine K, K?tter P, Louis EJ, Messenguy F, Mewes HW, Hoheisel JD
Nature387(6632 Suppl)87-90(1997 May)

Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)

Tfs1p may act as a bridge between cell signaling and intermediate metabolism in yeast.
Title: Interaction proteomics suggests a new role for the Tfs1 protein in yeast.

The results obtained demonstrate that the inhibition of Ira2p by Tfs1p is the predominant function under the conditions tested.
Title: A phenotypic study of TFS1 mutants differentially altered in the inhibition of Ira2p or CPY.

show that the accessibility of the surface pocket of Tfs1p, its N-terminal region and the specific electrostatic properties of a large surface region containing these two elements, play a crucial role in interaction with Ira2
Title: Molecular basis of the Tfs1/Ira2 interaction: a combined protein engineering and molecular modelling study.

The binding of I(C) to phospholipid membranes was first shown using a liposome-binding assay and by surface plasmon resonance , which revealed that the affinity of this inhibitor was not for phosphatidylethanolamine but for anionic phospholipids.
Title: Specific membrane binding of the carboxypeptidase Y inhibitor I(C), a phosphatidylethanolamine-binding protein family member.