Gene Symbol | UBP6 |
Entrez Gene ID | 850562 |
Full Name | ubiquitin-specific protease UBP6 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » UBP6 cDNA ORF clone
Gene Symbol | UBP6 |
Entrez Gene ID | 850562 |
Full Name | ubiquitin-specific protease UBP6 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001179975.1 | NP_116665.1 | ubiquitin-specific protease UBP6 |
Homo sapiens (human) | USP14 | NP_005142.1 |
Canis lupus familiaris (dog) | USP14 | XP_537306.2 |
Gallus gallus (chicken) | USP14 | XP_004939812.1 |
Xenopus tropicalis (tropical clawed frog) | usp14 | NP_001005641.1 |
Bos taurus (cattle) | USP14 | NP_001068657.1 |
Caenorhabditis elegans (roundworm) | usp-14 | NP_497006.1 |
Schizosaccharomyces pombe (fission yeast) | ubp6 | NP_594117.2 |
Pan troglodytes (chimpanzee) | USP14 | NP_001038961.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP009348 | XP_310014.4 |
Magnaporthe oryzae (rice blast fungus) | MGG_02970 | XP_003720730.1 |
Neurospora crassa | NCU01919 | XP_965550.1 |
Drosophila melanogaster (fruit fly) | CG5384 | NP_001260321.1 |
Saccharomyces cerevisiae (baker's yeast) | UBP6 | NP_116665.1 |
Kluyveromyces lactis | KLLA0A10791g | XP_451470.1 |
Eremothecium gossypii | AGOS_AEL029W | NP_984832.2 |
Arabidopsis thaliana (thale cress) | UBP7 | NP_566680.2 |
Oryza sativa (rice) | Os01g0550100 | NP_001043299.1 |
USP14 | XP_001090784.1 | |
Mus musculus (house mouse) | Usp14 | NP_067497.2 |
Rattus norvegicus (Norway rat) | Usp14 | NP_001008302.1 |
Danio rerio (zebrafish) | usp14 | NP_956267.1 |
Arabidopsis thaliana (thale cress) | UBP6 | NP_564596.1 |
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
Analysis of the nucleotide sequence of chromosome VI from Saccharomyces cerevisiae.
Murakami Y, Naitou M, Hagiwara H, Shibata T, Ozawa M, Sasanuma S, Sasanuma M, Tsuchiya Y, Soeda E, Yokoyama K
Nature genetics10(3)261-8(1995 Jul)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Electron microscopy analyses reveal that ubiquitin-bound Ubp6 contacts the N ring and AAA+ ring of the ATPase hexamer and is in proximity to the deubiquitinase Rpn11 in the proteasome.
Title: Ubp6 deubiquitinase controls conformational dynamics and substrate degradation of the 26S proteasome.
Fluorescently labeled tetra-Ub chains revealed endo-chain preference for Ubp6 acting on Lys(48) and random action for Rpn11.
Title: Disassembly of Lys11 and mixed linkage polyubiquitin conjugates provides insights into function of proteasomal deubiquitinases Rpn11 and Ubp6.
Results demonstrate that Sem1p and Ubp6p maintain telomeric heterochromatin structure through modulation of histone covalent modifications and association of silencing factors independently of the proteolytic function of the proteasome.
Title: Sem1p and Ubp6p orchestrate telomeric silencing by modulating histone H2B ubiquitination and H3 acetylation.
Results suggest that Ubp6 regulates both the nature and magnitude of proteasome activity.
Title: Deubiquitinating enzyme Ubp6 functions noncatalytically to delay proteasomal degradation.
The following UBP6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the UBP6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi00246 | |
Clone ID Related Accession (Same CDS sequence) | NM_001179975.1 | |
Accession Version | NM_001179975.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1500bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | ubiquitin-specific protease UBP6 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001138). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGAGCGGAG AAACGTTTGA GTTCAATATT AGACATTCTG GTAAAGTTTA CCCAATAACA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_116665.1 |
CDS | 1..1500 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001179975.1 |
1 | ATGAGCGGAG AAACGTTTGA GTTCAATATT AGACATTCTG GTAAAGTTTA CCCAATAACA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Life with 6000 genes. |
Analysis of the nucleotide sequence of chromosome VI from Saccharomyces cerevisiae. |