Gene Symbol | MMS1 |
Entrez Gene ID | 856293 |
Full Name | Mms1p |
Synonyms | RTT108,SLM6 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » MMS1 cDNA ORF clone
Gene Symbol | MMS1 |
Entrez Gene ID | 856293 |
Full Name | Mms1p |
Synonyms | RTT108,SLM6 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001184261.1 | NP_015490.1 | Mms1p |
Eremothecium gossypii | AGOS_ABR181W | NP_983129.1 |
Saccharomyces cerevisiae (baker's yeast) | MMS1 | NP_015490.1 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI.
Bussey H, Storms RK, Ahmed A, Albermann K, Allen E, Ansorge W, Araujo R, Aparicio A, Barrell B, Badcock K, Benes V, Botstein D, Bowman S, Br?ckner M, Carpenter J, Cherry JM, Chung E, Churcher C, Coster F, Davis K, Davis RW, Dietrich FS, Delius H, DiPaolo T, Hani J
Nature387(6632 Suppl)103-5(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
propose a mechanistic model in which Mms1 binds to specific G-rich/G4 motif located on the lagging strand template for DNA replication and supports Pif1 function, DNA replication and genome integrity
Title: Mms1 binds to G-rich regions in Saccharomyces cerevisiae and influences replication and genome stability.
Cul8-Mms1, as part of various protein complexes, is involved in the regulation of chromatin metabolism
Title: Cul8/Rtt101 forms a variety of protein complexes that regulate DNA damage response and transcriptional silencing.
Data suggest that in the absence of telomerase, a very short telomere is first maintained in a pre-signalling state by a RAD52-MMS1-dependent pathway and then switches to a signalling state leading to senescence through a Mec1p-dependent checkpoint.
Title: A two-step model for senescence triggered by a single critically short telomere.
Rtt101(Mms1) ubiquitin ligase complex might be required to reorganize replication forks that encounter DNA lesions.
Title: Rtt101 and Mms1 in budding yeast form a CUL4(DDB1)-like ubiquitin ligase that promotes replication through damaged DNA.
cells lacking MMS1 have severly defective recombination between sister chromatids or between homologous chromosomes induced by agents that block replisomes and are defective in recovery from Methylmethane Sulfonate-induced replisome stalling
Title: Budding yeast Mms22 and Mms1 regulate homologous recombination induced by replisome blockage.
The following MMS1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MMS1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi05111 | |
Clone ID Related Accession (Same CDS sequence) | NM_001184261.1 | |
Accession Version | NM_001184261.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 4224bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | Mms1p | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001148). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGCTAGGTT TGCGAACTCA TGGTTTAGAC AGGTATGAAC ATTATATTCG TCGCCCGTCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_015490.1 |
CDS | 1..4224 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001184261.1 |
1 | ATGCTAGGTT TGCGAACTCA TGGTTTAGAC AGGTATGAAC ATTATATTCG TCGCCCGTCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI. |
Life with 6000 genes. |