KAR1 cDNA ORF clone, Saccharomyces cerevisiae S288C

The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its evolutionary implications.
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Nature387(6632 Suppl)93-8(1997 May)

Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)

Kar1 binding is restricted to Sfi1-C-terminal and Sfi1 C-terminal centrin-binding repeats, and centrin and Kar1 provide cross-links, while Sfi1-C-terminal stabilizes the bridge and ensures timely spindle pole body separation.
Title: Kar1 binding to Sfi1 C-terminal regions anchors the SPB bridge to the nuclear envelope.

Functions of Nud1p are connected to the ability of Spc72p to bind to the outer plaque and half-bridge (via Kar1p) of the SPB.
Title: Nud1p, the yeast homolog of Centriolin, regulates spindle pole body inheritance in meiosis.

kar1 has a role in nuclear congression and nuclear fusion
Title: Bud selection and apoptosis-like degradation of nuclei in yeast heterokaryons: a KAR1 effect.