PDR1 cDNA ORF clone, Saccharomyces cerevisiae S288C

Gene
Clones
gRNAs

Summary

Gene Symbol	PDR1
Entrez Gene ID	852871
Full Name	drug-responsive transcription factor PDR1
Synonyms	AMY1,ANT1,BOR2,CYH3,NRA2,SMR2,TIL1,TPE1,TPE3
Gene Type	protein-coding
Organism	Saccharomyces cerevisiae S288C

mRNA and Protein(s)

mRNA	Protein	Name
NM_001180878.1	NP_011502.1	drug-responsive transcription factor PDR1

Pathways from BioSystems

Homologies

Saccharomyces cerevisiae (baker's yeast)	PDR1	NP_011502.1
Saccharomyces cerevisiae (baker's yeast)	PDR3	NP_009548.1

Gene Ontology
Bibliography

Related articles in PubMed

The nucleotide sequence of Saccharomyces cerevisiae chromosome VII.
Tettelin H, Agostoni Carbone ML, Albermann K, Albers M, Arroyo J, Backes U, Barreiros T, Bertani I, Bjourson AJ, Br?ckner M, Bruschi CV, Carignani G, Castagnoli L, Cerdan E, Clemente ML, Coblenz A, Coglievina M, Coissac E, Defoor E, Del Bino S, Delius H, Delneri D, de Wergifosse P, Dujon B, Kleine K
Nature387(6632 Suppl)81-4(1997 May)

Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

In response to organic solvent stress, only Pdr3p contributed to the regulation of downstream genes of the PDR pathway, while Pdr1p had a rather inhibitory role on transcriptional induction
Title: Activation of the mitochondrial signaling pathway in response to organic solvent stress in yeast.

bakers yeast containing mutations within the transcriptional regulator Pdr1 has been used to overexpress various membrane proteins including for example the ABC transporters Pdr5 and Yor1, respectively
Title: New examples of membrane protein expression and purification using the yeast based Pdr1-3 expression strategy.

Unfolding of Zuo1's C-terminal helical bundle domain results in ribosome dissociation followed by activation of Pdr1 via a direct interaction.
Title: Unfolding of the C-terminal domain of the J-protein Zuo1 releases autoinhibition and activates Pdr1-dependent transcription.

Aus1 and Pdr11 are required for sterol uptake.
Title: Tritium suicide selection identifies proteins involved in the uptake and intracellular transport of sterols in Saccharomyces cerevisiae.

Organic-solvent tolerance in Saccharomyces cerevisiae strain on point mutation of the transcription factor Pdr1p.
Title: Discovery of a modified transcription factor endowing yeasts with organic-solvent tolerance and reconstruction of an organic-solvent-tolerant Saccharomyces cerevisiae strain.

The following PDR1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PDR1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OSi02222	NM_001180878.1 Latest version!	Saccharomyces cerevisiae S288C drug-responsive transcription factor PDR1 (PDR1), partial mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$629.30 $899.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PDR1 ( NM_001180878.1 ) cDNA ORF clone, Saccharomyces cerevisiae S288C -> NP_011502.1 Saccharomyces cerevisiae S288C drug-responsive transcription factor PDR1 (PDR1), partial mRNA.

Price & Availability↑

CloneID	OSi02222
Clone ID Related Accession (Same CDS sequence)	NM_001180878.1
Accession Version	NM_001180878.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3207bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-31
Organism	Saccharomyces cerevisiae S288C
Product	drug-responsive transcription factor PDR1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001139). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends.

ATGCGAGGCT TGACACCTAA GAACGGTGTA CATATTGAGA CGGGTCCGGA TACAGAATCG 
TCCGCGGACT CCAGCAACTT TTCTACAGGT TTCAGCGGCA AGATTCGTAA GCCAAGGTCG 
AAAGTAAGTA AAGCGTGCGA TAACTGTAGA AAAAGAAAGA TAAAATGTAA TGGGAAGTTT 
CCCTGCGCAA GCTGTGAGAT ATATTCATGT GAGTGCACGT TCAGCACTAG ACAAGGTGGC 
GCTCGAATAA AAAACCTTCA CAAGACGAGT TTGGAAGGTA CAACCGTACA AGTCAAAGAG 
GAAACAGATT CCAGTTCGAC TTCTTTTTCT AATCCTCAGC GATGTACAGA CGGGCCATGC 
GCAGTGGAAC AACCAACGAA ATTTTTTGAG AATTTCAAGC TAGGTGGTCG TAGTAGTGGT 
GATAATAGCG GAAGTGATGG GAAGAATGAC GACGATGTGA ATAGAAACGG TTTTTATGAA 
GACGATAGCG AATCACAGGC AACTTTGACA TCTCTACAAA CCACTCTGAA AAATTTGAAG 
GAGATGGCTC ATTTAGGTAC ACATGTAACC TCAGCCATCG AGAGCATTGA ACTTCAGATA 
AGTGACTTGC TTAAGCGATG GGAACCCAAA GTGAGGACCA AAGAATTAGC AACAACGAAA 
TTTTACCCTA ATAAATCAAT AGAAACTCAA TTGATGAAAA ACAAATACTG TGATGTGGTA 
CATTTGACAA GATATGCCGC TTGGTCAAAC AATAAGAAGG ACCAAGATAC TTCTAGTCAA 
CCTTTGATCG ACGAAATCTT TGGTTTGTAC TCTCCTTTCC AATTTTTGTC ACTTCAAGGT 
ATTGGTAAAT GTTTCCAAAA TTATAGATCC AAATCCAAAT GCGAGATTTT TCCCAGGACC 
GCCAAGGAAA CCATATACAT CATGTTAAGG TTTTTCGACG TTTGTTTTCA TCACATCAAC 
CAAGGCTGTG TCTCCATAGC TAATCCCCTG GAAAACTACC TACAGAAAAT GAATCTTTTA 
CCTTCAACCC CATCTTCGAT ATCATCTGCA GGGAGCCCGA ATACAGCACA CACAAAATCG 
CATGTTGCGT TAGTGATAAA TCACTTACCG CAGCCCTTTG TGAGAAATAT AACCGGAATA 
AGTAATTCTG AGCTACTAAG CGAAATGAAT AATGATATCA GCATGTTTGG CATTTTATTG 
AAGATGTTGG ATATGCATAA AAATTCCTAC CAGAACTTCC TAATGGAAAT CACATCTAAC 
CCCTCCGTGG CTAAAAACAC GCAGTCAATT GATGTCTTGC AGGAATTCAT CCATTATTGT 
CAAGCTGGAG AGGCGCTAAT CGCCTTATGT TACAGCTATT ATAATTCTAC ATTATACAAC 
TACGTGGACT TCACATGCGA CATAACGCAT TTAGAGCAAC TTCTATACTT TTTGGATCTG 
CTATTTTGGC TATCGGAAAT ATACGGTTTT GAAAAAGTCT TGAACGTAGC AGTTCATTTT 
GTTTCAAGAG TTGGTTTATC AAGGTGGGAA TTTTACGTGG GTCTTGATGA AAACTTTGCT 
GAAAGAAGAA GAAATCTCTG GTGGAAAGCT TTCTATTTCG AGAAAACTTT AGCCTCTAAA 
CTTGGCTATC CTTCGAACAT TGATGACTCC AAAATCAATT GTTTATTACC TAAGAATTTT 
CGAGATGTTG GGTTCTTGGA TAATAGAGAT TTTATCGAGA ACGTCCACTT AGTTCGCAGG 
AGCGAAGCTT TTGACAACAT GTGCATATCC GACTTAAAAT ACTATGGCGA ATTAGCTGTC 
TTACAAATAG TCAGCCATTT CTCATCATCT GTTTTATTCA ATGAAAAATT CACGTCAATT 
AGGAATACAT CAAAACCATC TGTTGTTAGA GAGAAACTAC TCTTCGAGGT ACTCGAGATT 
TTTAACGAAA CAGAAATGAA ATATGATGCT ATCAAAGAGC AAACTGGAAA ATTGTTCGAT 
ATTGCATTCT CTAAAGATAG TACTGAACTC AAAGTTTCAA GAGAGGATAA GATTATGGCT 
TCAAAATTTG TTCTATTTTA CGAGCACCAT TTCTGCAGAA TGGTTAACGA ATCTGATAAT 
ATTGTCGCCA GATTATGCGT GCACAGAAGG CCCTCAATAC TAATTGAAAA CTTGAAAATA 
TACCTTCACA AGATTTACAA ATCATGGACC GATATGAACA AAATCTTATT AGACTTTGAC 
AACGATTATT CCGTATACCG TTCGTTCGCC CATTATTCTA TCAGTTGCAT TATTTTGGTA 
TCACAAGCAT TCTCAGTGGC CGAATTCATT AAAGTAAATG ACGTTGTGAA TATGATTAGA 
GTCTTCAAAA GATTTTTGGA TATAAAAATT TTTTCCGAAA ATGAGACCAA TGAGCATGTC 
TTCAACAGCC AAAGCTTTAA AGACTATACA AGAGCTTTTT CTTTCCTGAC AATCGTCACT 
CGTATCATGC TTTTGGCATA CGGAGAGTCC TCTAGCACCA ACCTCGATGT TATCTCCAAA 
TATATTGATG AGAATGCGCC AGATTTAAAA GGTATAATAG AACTTGTCTT GGATACAAAC 
TCTTGCGCTT ATCGATTTTT ATTAGAACCT GTTCAGAAGT CAGGATTCCA TTTAACGGTC 
TCACAAATGT TGAAAAATAG AAAGTTTCAG GAACCACTAA TGTCAAATGA AGATAATAAG 
CAGATGAAGC ATAATTCGGG AAAAAATTTG AATCCGGATC TCCCAAGTCT TAAGACGGGC 
ACTTCATGCT TACTAAATGG CATTGAATCG CCTCAATTGC CATTCAATGG TCGCTCAGCA 
CCTTCCCCAG TGAGAAACAA CTCACTACCG GAGTTTGCAC AATTGCCTTC ATTTAGGTCA 
TTATCCGTGT CTGATATGAT CAATCCCGAT TACGCGCAAC CAACAAATGG GCAAAATAAT 
ACGCAAGTCC AATCTAATAA ACCAATCAAT GCTCAGCAGC AAATACCCAC TTCAGTACAA 
GTACCATTTA TGAACACAAA TGAAATCAAT AACAACAACA ACAACAACAA CAACAATAAA 
AACAATATTA ACAATATTAA CAACAACAAC AGTAACAATT TTTCTGCAAC TAGTTTTAAT 
TTGGGGACAC TAGATGAATT TGTTAATAAC GGTGATCTTG AGGACCTCTA CAGTATCCTG 
TGGAGCGACG TTTATCCAGA TAGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_011502.1
CDS	1..3207
Translation	MRGLTPKNGVHIETGPDTESSADSSNFSTGFSGKIRKPRSKVSKACDNCRKRKIKCNGKFPCASCEIYSCECTFSTRQGGARIKNLHKTSLEGTTVQVKEETDSSSTSFSNPQRCTDGPCAVEQPTKFFENFKLGGRSSGDNSGSDGKNDDDVNRNGFYEDDSESQATLTSLQTTLKNLKEMAHLGTHVTSAIESIELQISDLLKRWEPKVRTKELATTKFYPNKSIETQLMKNKYCDVVHLTRYAAWSNNKKDQDTSSQPLIDEIFGLYSPFQFLSLQGIGKCFQNYRSKSKCEIFPRTAKETIYIMLRFFDVCFHHINQGCVSIANPLENYLQKMNLLPSTPSSISSAGSPNTAHTKSHVALVINHLPQPFVRNITGISNSELLSEMNNDISMFGILLKMLDMHKNSYQNFLMEITSNPSVAKNTQSIDVLQEFIHYCQAGEALIALCYSYYNSTLYNYVDFTCDITHLEQLLYFLDLLFWLSEIYGFEKVLNVAVHFVSRVGLSRWEFYVGLDENFAERRRNLWWKAFYFEKTLASKLGYPSNIDDSKINCLLPKNFRDVGFLDNRDFIENVHLVRRSEAFDNMCISDLKYYGELAVLQIVSHFSSSVLFNEKFTSIRNTSKPSVVREKLLFEVLEIFNETEMKYDAIKEQTGKLFDIAFSKDSTELKVSREDKIMASKFVLFYEHHFCRMVNESDNIVARLCVHRRPSILIENLKIYLHKIYKSWTDMNKILLDFDNDYSVYRSFAHYSISCIILVSQAFSVAEFIKVNDVVNMIRVFKRFLDIKIFSENETNEHVFNSQSFKDYTRAFSFLTIVTRIMLLAYGESSSTNLDVISKYIDENAPDLKGIIELVLDTNSCAYRFLLEPVQKSGFHLTVSQMLKNRKFQEPLMSNEDNKQMKHNSGKNLNPDLPSLKTGTSCLLNGIESPQLPFNGRSAPSPVRNNSLPEFAQLPSFRSLSVSDMINPDYAQPTNGQNNTQVQSNKPINAQQQIPTSVQVPFMNTNEINNNNNNNNNNKNNINNINNNNSNNFSATSFNLGTLDEFVNNGDLEDLYSILWSDVYPDS

Target ORF information:

RefSeq Version	NM_001180878.1
Organism	Saccharomyces cerevisiae S288C
Definition	Saccharomyces cerevisiae S288C drug-responsive transcription factor PDR1 (PDR1), partial mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001180878.1

ORF Insert Sequence:

ATGCGAGGCT TGACACCTAA GAACGGTGTA CATATTGAGA CGGGTCCGGA TACAGAATCG 
TCCGCGGACT CCAGCAACTT TTCTACAGGT TTCAGCGGCA AGATTCGTAA GCCAAGGTCG 
AAAGTAAGTA AAGCGTGCGA TAACTGTAGA AAAAGAAAGA TAAAATGTAA TGGGAAGTTT 
CCCTGCGCAA GCTGTGAGAT ATATTCATGT GAGTGCACGT TCAGCACTAG ACAAGGTGGC 
GCTCGAATAA AAAACCTTCA CAAGACGAGT TTGGAAGGTA CAACCGTACA AGTCAAAGAG 
GAAACAGATT CCAGTTCGAC TTCTTTTTCT AATCCTCAGC GATGTACAGA CGGGCCATGC 
GCAGTGGAAC AACCAACGAA ATTTTTTGAG AATTTCAAGC TAGGTGGTCG TAGTAGTGGT 
GATAATAGCG GAAGTGATGG GAAGAATGAC GACGATGTGA ATAGAAACGG TTTTTATGAA 
GACGATAGCG AATCACAGGC AACTTTGACA TCTCTACAAA CCACTCTGAA AAATTTGAAG 
GAGATGGCTC ATTTAGGTAC ACATGTAACC TCAGCCATCG AGAGCATTGA ACTTCAGATA 
AGTGACTTGC TTAAGCGATG GGAACCCAAA GTGAGGACCA AAGAATTAGC AACAACGAAA 
TTTTACCCTA ATAAATCAAT AGAAACTCAA TTGATGAAAA ACAAATACTG TGATGTGGTA 
CATTTGACAA GATATGCCGC TTGGTCAAAC AATAAGAAGG ACCAAGATAC TTCTAGTCAA 
CCTTTGATCG ACGAAATCTT TGGTTTGTAC TCTCCTTTCC AATTTTTGTC ACTTCAAGGT 
ATTGGTAAAT GTTTCCAAAA TTATAGATCC AAATCCAAAT GCGAGATTTT TCCCAGGACC 
GCCAAGGAAA CCATATACAT CATGTTAAGG TTTTTCGACG TTTGTTTTCA TCACATCAAC 
CAAGGCTGTG TCTCCATAGC TAATCCCCTG GAAAACTACC TACAGAAAAT GAATCTTTTA 
CCTTCAACCC CATCTTCGAT ATCATCTGCA GGGAGCCCGA ATACAGCACA CACAAAATCG 
CATGTTGCGT TAGTGATAAA TCACTTACCG CAGCCCTTTG TGAGAAATAT AACCGGAATA 
AGTAATTCTG AGCTACTAAG CGAAATGAAT AATGATATCA GCATGTTTGG CATTTTATTG 
AAGATGTTGG ATATGCATAA AAATTCCTAC CAGAACTTCC TAATGGAAAT CACATCTAAC 
CCCTCCGTGG CTAAAAACAC GCAGTCAATT GATGTCTTGC AGGAATTCAT CCATTATTGT 
CAAGCTGGAG AGGCGCTAAT CGCCTTATGT TACAGCTATT ATAATTCTAC ATTATACAAC 
TACGTGGACT TCACATGCGA CATAACGCAT TTAGAGCAAC TTCTATACTT TTTGGATCTG 
CTATTTTGGC TATCGGAAAT ATACGGTTTT GAAAAAGTCT TGAACGTAGC AGTTCATTTT 
GTTTCAAGAG TTGGTTTATC AAGGTGGGAA TTTTACGTGG GTCTTGATGA AAACTTTGCT 
GAAAGAAGAA GAAATCTCTG GTGGAAAGCT TTCTATTTCG AGAAAACTTT AGCCTCTAAA 
CTTGGCTATC CTTCGAACAT TGATGACTCC AAAATCAATT GTTTATTACC TAAGAATTTT 
CGAGATGTTG GGTTCTTGGA TAATAGAGAT TTTATCGAGA ACGTCCACTT AGTTCGCAGG 
AGCGAAGCTT TTGACAACAT GTGCATATCC GACTTAAAAT ACTATGGCGA ATTAGCTGTC 
TTACAAATAG TCAGCCATTT CTCATCATCT GTTTTATTCA ATGAAAAATT CACGTCAATT 
AGGAATACAT CAAAACCATC TGTTGTTAGA GAGAAACTAC TCTTCGAGGT ACTCGAGATT 
TTTAACGAAA CAGAAATGAA ATATGATGCT ATCAAAGAGC AAACTGGAAA ATTGTTCGAT 
ATTGCATTCT CTAAAGATAG TACTGAACTC AAAGTTTCAA GAGAGGATAA GATTATGGCT 
TCAAAATTTG TTCTATTTTA CGAGCACCAT TTCTGCAGAA TGGTTAACGA ATCTGATAAT 
ATTGTCGCCA GATTATGCGT GCACAGAAGG CCCTCAATAC TAATTGAAAA CTTGAAAATA 
TACCTTCACA AGATTTACAA ATCATGGACC GATATGAACA AAATCTTATT AGACTTTGAC 
AACGATTATT CCGTATACCG TTCGTTCGCC CATTATTCTA TCAGTTGCAT TATTTTGGTA 
TCACAAGCAT TCTCAGTGGC CGAATTCATT AAAGTAAATG ACGTTGTGAA TATGATTAGA 
GTCTTCAAAA GATTTTTGGA TATAAAAATT TTTTCCGAAA ATGAGACCAA TGAGCATGTC 
TTCAACAGCC AAAGCTTTAA AGACTATACA AGAGCTTTTT CTTTCCTGAC AATCGTCACT 
CGTATCATGC TTTTGGCATA CGGAGAGTCC TCTAGCACCA ACCTCGATGT TATCTCCAAA 
TATATTGATG AGAATGCGCC AGATTTAAAA GGTATAATAG AACTTGTCTT GGATACAAAC 
TCTTGCGCTT ATCGATTTTT ATTAGAACCT GTTCAGAAGT CAGGATTCCA TTTAACGGTC 
TCACAAATGT TGAAAAATAG AAAGTTTCAG GAACCACTAA TGTCAAATGA AGATAATAAG 
CAGATGAAGC ATAATTCGGG AAAAAATTTG AATCCGGATC TCCCAAGTCT TAAGACGGGC 
ACTTCATGCT TACTAAATGG CATTGAATCG CCTCAATTGC CATTCAATGG TCGCTCAGCA 
CCTTCCCCAG TGAGAAACAA CTCACTACCG GAGTTTGCAC AATTGCCTTC ATTTAGGTCA 
TTATCCGTGT CTGATATGAT CAATCCCGAT TACGCGCAAC CAACAAATGG GCAAAATAAT 
ACGCAAGTCC AATCTAATAA ACCAATCAAT GCTCAGCAGC AAATACCCAC TTCAGTACAA 
GTACCATTTA TGAACACAAA TGAAATCAAT AACAACAACA ACAACAACAA CAACAATAAA 
AACAATATTA ACAATATTAA CAACAACAAC AGTAACAATT TTTCTGCAAC TAGTTTTAAT 
TTGGGGACAC TAGATGAATT TGTTAATAAC GGTGATCTTG AGGACCTCTA CAGTATCCTG 
TGGAGCGACG TTTATCCAGA TAGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The nucleotide sequence of Saccharomyces cerevisiae chromosome VII.
Nature387(6632 Suppl)81-4(1997 May)
Tettelin H,Agostoni Carbone ML,Albermann K,Albers M,Arroyo J,Backes U,Barreiros T,Bertani I,Bjourson AJ,Br?ckner M,Bruschi CV,Carignani G,Castagnoli L,Cerdan E,Clemente ML,Coblenz A,Coglievina M,Coissac E,Defoor E,Del Bino S,Delius H,Delneri D,de Wergifosse P,Dujon B,Kleine K

Life with 6000 genes.
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
Goffeau A,Barrell BG,Bussey H,Davis RW,Dujon B,Feldmann H,Galibert F,Hoheisel JD,Jacq C,Johnston M,Louis EJ,Mewes HW,Murakami Y,Philippsen P,Tettelin H,Oliver SG

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PDR1 cDNA ORF clone, Saccharomyces cerevisiae S288C

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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