Gene Symbol | HPR1 |
Entrez Gene ID | 851716 |
Full Name | Hpr1p |
Synonyms | TRF1 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » HPR1 cDNA ORF clone
Gene Symbol | HPR1 |
Entrez Gene ID | 851716 |
Full Name | Hpr1p |
Synonyms | TRF1 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001180445.1 | NP_010422.1 | Hpr1p |
Kluyveromyces lactis | KLLA0F11528g | XP_455605.1 |
Eremothecium gossypii | AGOS_AGL181C | NP_986486.1 |
Saccharomyces cerevisiae (baker's yeast) | HPR1 | NP_010422.1 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome IV.
Jacq C, Alt-M?rbe J, Andre B, Arnold W, Bahr A, Ballesta JP, Bargues M, Baron L, Becker A, Biteau N, Bl?cker H, Blugeon C, Boskovic J, Brandt P, Br?ckner M, Buitrago MJ, Coster F, Delaveau T, del Rey F, Dujon B, Eide LG, Garcia-Cantalejo JM, Goffeau A, Gomez-Peris A, Zaccaria P
Nature387(6632 Suppl)75-8(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
This work establishes a genome-wide function for THO-Sub2 in transcription elongation and mRNP biogenesis that function to prevent the accumulation of transcription-mediated replication obstacles, including R-loops.
Title: Genome-wide function of THO/TREX in active genes prevents R-loop-dependent replication obstacles.
Interaction with Hpr1 is required for Mex67 UBA domain to bind polyubiquitin, possibly by inducing an helix H4-dependent conformational change.
Title: Coordination of Hpr1 and ubiquitin binding by the UBA domain of the mRNA export factor Mex67.
isolated a mutant, hpr1-101, with a strong defect in transcription, as observed for lacZ, and a general defect in mRNA export that did not display a relevant hyperrecombination phenotype
Title: An hpr1 point mutation that impairs transcription and mRNP biogenesis without increasing recombination.
Data show that Rsp5p is responsible for the ubiquitylation of Hpr1p that also involves the ubiquitin-conjugating enzyme Ubc4p.
Title: The mRNA nuclear export factor Hpr1 is regulated by Rsp5-mediated ubiquitylation.
The following HPR1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the HPR1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi01223 | |
Clone ID Related Accession (Same CDS sequence) | NM_001180445.1 | |
Accession Version | NM_001180445.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2259bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | Hpr1p | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001136). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGTCTAATA CCGAGGAATT GATCCAAAAC TCAATAGGTT TTCTCCAGAA AACTTTTAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_010422.1 |
CDS | 1..2259 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001180445.1 |
1 | ATGTCTAATA CCGAGGAATT GATCCAAAAC TCAATAGGTT TTCTCCAGAA AACTTTTAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome IV. |
Life with 6000 genes. |