Gene Symbol | CDC24 |
Entrez Gene ID | 851190 |
Full Name | Rho family guanine nucleotide exchange factor CDC24 |
Synonyms | CLS4 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » CDC24 cDNA ORF clone
Gene Symbol | CDC24 |
Entrez Gene ID | 851190 |
Full Name | Rho family guanine nucleotide exchange factor CDC24 |
Synonyms | CLS4 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001178186.1 | NP_009359.1 | Rho family guanine nucleotide exchange factor CDC24 |
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
The nucleotide sequence of chromosome I from Saccharomyces cerevisiae.
Bussey H, Kaback DB, Zhong W, Vo DT, Clark MW, Fortin N, Hall J, Ouellette BF, Keng T, Barton AB
Proceedings of the National Academy of Sciences of the United States of America92(9)3809-13(1995 Apr)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Biochemical analysis confirmed that this mutation disturbs the interaction with Bem1 but not the fold of the protein. The larger dataset obtained by NGS achieved a more complete representation of the bipartite interaction interface of Cdc24.
Title: A Split-Ubiquitin Based Strategy Selecting for Protein Complex-Interfering Mutations.
We propose that the NH2-terminal region unmasks the DH and PB1 domains, leading to the activation of Cdc42 and interaction with Bem1, respectively, to initiate cell polarization
Title: Essential role of the NH2-terminal region of Cdc24 guanine nucleotide exchange factor in its initial polarized localization in Saccharomyces cerevisiae.
These data support roles for Boi2p, Ent2p, Hua1p, Tos2p, and for Cdc24p phosphorylation in targeting Cdc24p to growth sites.
Title: Multiple proteins and phosphorylations regulate Saccharomyces cerevisiae Cdc24p localization.
study presents the tertiary structure of the heterodimer of Bem1 and Cdc24 PB1 domains determined by NMR spectroscopy
Title: NMR structure of the heterodimer of Bem1 and Cdc24 PB1 domains from Saccharomyces cerevisiae.
Cdc24p oligomerization regulates Cdc42p activation via its localization
Title: Oligomerization regulates the localization of Cdc24, the Cdc42 activator in Saccharomyces cerevisiae.
The following CDC24 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CDC24 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi00777 | |
Clone ID Related Accession (Same CDS sequence) | NM_001178186.1 | |
Accession Version | NM_001178186.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2565bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | Rho family guanine nucleotide exchange factor CDC24 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001133). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGGCGATCC AAACCCGTTT TGCCTCGGGC ACATCTTTAT CCGATTTGAA ACCAAAACCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_009359.1 |
CDS | 1..2565 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001178186.1 |
1 | ATGGCGATCC AAACCCGTTT TGCCTCGGGC ACATCTTTAT CCGATTTGAA ACCAAAACCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Life with 6000 genes. |
The nucleotide sequence of chromosome I from Saccharomyces cerevisiae. |