Gene Symbol | RAD18 |
Entrez Gene ID | 850430 |
Full Name | E3 ubiquitin-protein ligase RAD18 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » RAD18 cDNA ORF clone
Gene Symbol | RAD18 |
Entrez Gene ID | 850430 |
Full Name | E3 ubiquitin-protein ligase RAD18 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001178777.1 | NP_009992.1 | E3 ubiquitin-protein ligase RAD18 |
Saccharomyces cerevisiae (baker's yeast) | RAD18 | NP_009992.1 |
Kluyveromyces lactis | KLLA0C08756g | XP_452591.1 |
Eremothecium gossypii | AGOS_AAR049C | NP_982590.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_04175 | XP_003719650.1 |
Schizosaccharomyces pombe (fission yeast) | rhp18 | NP_595423.1 |
Neurospora crassa | NCU05210 | XP_962209.2 |
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
The complete DNA sequence of yeast chromosome III.
Oliver SG, van der Aart QJ, Agostoni-Carbone ML, Aigle M, Alberghina L, Alexandraki D, Antoine G, Anwar R, Ballesta JP, Benit P
Nature357(6373)38-46(1992 May)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The Pol30-K196 residue plays a critical role in budding yeast DNA post-replication repair through interaction with Rad18.
Title: The Pol30-K196 residue plays a critical role in budding yeast DNA postreplication repair through interaction with Rad18.
following UV-induced damage, reactivation of Rad18, even after prolonged G2 arrest, restores viability and genome integrity.
Title: The preference for error-free or error-prone postreplication repair in Saccharomyces cerevisiae exposed to low-dose methyl methanesulfonate is cell cycle dependent.
The results imply that sumoylated PCNA is the physiological ubiquitylation target of budding yeast Rad18.
Title: A SUMO-interacting motif activates budding yeast ubiquitin ligase Rad18 towards SUMO-modified PCNA.
In this study we showed that DNA damage induced by hydrogen peroxide at the same mutagen doses causes significantly more mutations and lethal events in the rad18 mutant cells compared to control wild-type cells
Title: [RAD18 gene product of yeast Saccharomyces cerevisiae controls mutagenesis induced by hydrogen peroxide].
Rad17, a subunit of the PCNA-like 9-1-1 checkpoint clamp is ubiquitylated; however, in contrast to previous results, modification of Rad17 is found to be independent of DNA damage, the Rad6-Rad18 complex.
Title: Ubiquitylation of the 9-1-1 checkpoint clamp is independent of rad6-rad18 and DNA damage.
The following RAD18 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RAD18 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi00133 | |
Clone ID Related Accession (Same CDS sequence) | NM_001178777.1 | |
Accession Version | NM_001178777.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1464bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | E3 ubiquitin-protein ligase RAD18 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001135). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGGACCACC AAATAACCAC TGCAAGCGAC TTCACGACTA CTTCAATACC GAGCCTGTAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_009992.1 |
CDS | 1..1464 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001178777.1 |
1 | ATGGACCACC AAATAACCAC TGCAAGCGAC TTCACGACTA CTTCAATACC GAGCCTGTAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Life with 6000 genes. |
The complete DNA sequence of yeast chromosome III. |