Vegfb cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Vegfb
Entrez Gene ID	89811
Full Name	vascular endothelial growth factor B
General protein information	Preferred Names vascular endothelial growth factor B Names vascular endothelial growth factor B VEGF-B VEGF-related factor VRF
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q43
Summary	mouse homolog is a growth factor; involved in the promotion of angiogenesis [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_006230910.3	XP_006230972.1	vascular endothelial growth factor B isoform X1
XM_006230912.3	XP_006230974.1	vascular endothelial growth factor B isoform X2
NM_053549.1	NP_446001.1	vascular endothelial growth factor B precursor
XM_006230911.3	XP_006230973.1	vascular endothelial growth factor B isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	VEGFB	NP_001230662.1
Pan troglodytes (chimpanzee)	VEGFB	XP_001144738.2
Canis lupus familiaris (dog)	VEGFB	XP_533245.2
Rattus norvegicus (Norway rat)	Vegfb	NP_446001.1
	LOC722115	XP_001118308.1
Mus musculus (house mouse)	Vegfb	NP_001172093.1
Bos taurus (cattle)	VEGFB	XP_005227276.1

Gene Ontology
Bibliography

Related articles in PubMed

Loss of VEGFB and its signaling in the diabetic heart is associated with increased cell death signaling.
Lal N, Chiu AP, Wang F, Zhang D, Jia J, Wan A, Vlodavsky I, Hussein B, Rodrigues B
American journal of physiology. Heart and circulatory physiology312(6)H1163-H1175(2017 Jun)

Methylation patterns of Vegfb promoter are associated with gene and protein expression levels: the effects of dietary fatty acids.
Monastero R, Garc?a-Serrano S, Lago-Sampedro A, Rodr?guez-Pacheco F, Colomo N, Morcillo S, Mart?n-Nu?ez GM, Gomez-Zumaquero JM, Garc?a-Fuentes E, Soriguer F, Rojo-Mart?nez G, Garc?a-Escobar E
European journal of nutrition56(2)715-726(2017 Mar)

Oral Platelet-Derived Growth Factor and Vascular Endothelial Growth Factor Inhibitor Sunitinib Prevents Chronic Allograft Injury in Experimental Kidney Transplantation Model.
Rintala JM, Savikko J, Palin N, Rintala SE, Koskinen PK, von Willebrand E
Transplantation100(1)103-10(2016 Jan)

Vascular endothelial growth factor B prevents the shift in the ocular dominance distribution of visual cortical neurons in monocularly deprived rats.
Shan L, Yong H, Song Q, Wei Y, Qin R, Zhang G, Xu M, Zhang S
Experimental eye research10917-21(2013 Apr)

Cardiac VEGF-B expression decreases along with cardiac allograft unload.
Raissadati A, Tuuminen R
Journal of cardiac failure18(11)879-80(2012 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Loss of VEGFB and its downstream signaling is an early event following hyperglycemia, is sustained with disease progression, and could explain diabetic cardiomyopathy.
Title: Loss of VEGFB and its signaling in the diabetic heart is associated with increased cell death signaling.

Data suggest that dietary fatty acids create epigenetic/nutrigenomic changes in methylation levels of CpG island at Vegfb promoter and changes in Vegfb expression in white adipocytes in vivo and in vitro, with particular up-regulation of DNA methylation by linoleic acid; Vegfb promoter methylation levels are closely related to Vegfb gene expression in visceral and subcutaneous adipose tissue.
Title: Methylation patterns of Vegfb promoter are associated with gene and protein expression levels: the effects of dietary fatty acids.

Combined inhibition of PGDF and VEGF with sunitinib prevents chronic rejection changes in experimental kidney transplantation.
Title: Oral Platelet-Derived Growth Factor and Vascular Endothelial Growth Factor Inhibitor Sunitinib Prevents Chronic Allograft Injury in Experimental Kidney Transplantation Model.

VEGF-B has important effects on the functional architecture of the visual cortex.
Title: Vascular endothelial growth factor B prevents the shift in the ocular dominance distribution of visual cortical neurons in monocularly deprived rats.

Cardiac VEGF-B mRNA expression decreases following heart transplantation.
Title: Cardiac VEGF-B expression decreases along with cardiac allograft unload.

The following Vegfb gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Vegfb cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa09864	NM_053549.1 Latest version!	Rattus norvegicus vascular endothelial growth factor B (Vegfb), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
ORa23844	XM_006230911.3 Latest version!	Rattus norvegicus vascular endothelial growth factor B (Vegfb), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
ORa23844	XM_006230910.3 Latest version!	Rattus norvegicus vascular endothelial growth factor B (Vegfb), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
ORa23845	XM_006230912.3 Latest version!	Rattus norvegicus vascular endothelial growth factor B (Vegfb), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Vegfb ( NM_053549.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_446001.1 Rattus norvegicus vascular endothelial growth factor B (Vegfb), mRNA.

Price & Availability↑

CloneID	ORa09864
Clone ID Related Accession (Same CDS sequence)	NM_053549.1
Accession Version	NM_053549.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 561bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-19
Organism	Rattus norvegicus(Norway rat)
Product	vascular endothelial growth factor B precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC076395.1. On Mar 26, 2005 this sequence version replaced XM_342006.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC076395.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGAGCCCCC TGCTCCGTCG CTTGCTGCTT GTTGCGCTGC TGCAGCTGGC CTGTACCCAG 
GCCCCTGTGT CCCAGTTTGA TGGCCCCAGC CACCAGAAGA AAGTGGTGTC ATGGATAGAT 
GTTTATGCAC GTGCCACATG CCAGCCCAGG GAGGTGGTGG TACCTCTGAG CATGGAACTC 
ATGGGTAATG TGGTCAAACA ACTCGTGCCC AGCTGTGTGA CTGTGCAGCG CTGTGGTGGC 
TGCTGTCCTG ACGATGGCCT GGAGTGTGTG CCCATTGGGC AACACCAAGT CCGAATGCAG 
ATCCTCATGA TCCAGTACCC GAGCAGTCAG CTGGGGGAGA TGTCCCTGGA AGAACACAGC 
CAATGTGAAT GCAGACCAAA AAGAAAGGAG AGTGCTGTGA AGCCAGACAG CCCCAGGACC 
CTCTGCCCAC GCTGCACCCA GCGCCGTCAG CGCCCTGATC CCCGGACCTG CCGTTGCCGC 
TGCAGACGCC GCCGCTTCCT CCATTGCCAA GGGCGGGGCT TAGAGCTCAA CCCAGATACC 
TGCAGATCAT CAGAAACTTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_446001.1
CDS	256..816
Translation	MSPLLRRLLLVALLQLACTQAPVSQFDGPSHQKKVVSWIDVYARATCQPREVVVPLSMELMGNVVKQLVPSCVTVQRCGGCCPDDGLECVPIGQHQVRMQILMIQYPSSQLGEMSLEEHSQCECRPKRKESAVKPDSPRTLCPRCTQRRQRPDPRTCRCRCRRRRFLHCQGRGLELNPDTCRSSET

Target ORF information:

RefSeq Version	NM_053549.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus vascular endothelial growth factor B (Vegfb), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_053549.1

ORF Insert Sequence:

ATGAGCCCCC TGCTCCGTCG CTTGCTGCTT GTTGCGCTGC TGCAGCTGGC CTGTACCCAG 
GCCCCTGTGT CCCAGTTTGA TGGCCCCAGC CACCAGAAGA AAGTGGTGTC ATGGATAGAT 
GTTTATGCAC GTGCCACATG CCAGCCCAGG GAGGTGGTGG TACCTCTGAG CATGGAACTC 
ATGGGTAATG TGGTCAAACA ACTCGTGCCC AGCTGTGTGA CTGTGCAGCG CTGTGGTGGC 
TGCTGTCCTG ACGATGGCCT GGAGTGTGTG CCCATTGGGC AACACCAAGT CCGAATGCAG 
ATCCTCATGA TCCAGTACCC GAGCAGTCAG CTGGGGGAGA TGTCCCTGGA AGAACACAGC 
CAATGTGAAT GCAGACCAAA AAGAAAGGAG AGTGCTGTGA AGCCAGACAG CCCCAGGACC 
CTCTGCCCAC GCTGCACCCA GCGCCGTCAG CGCCCTGATC CCCGGACCTG CCGTTGCCGC 
TGCAGACGCC GCCGCTTCCT CCATTGCCAA GGGCGGGGCT TAGAGCTCAA CCCAGATACC 
TGCAGATCAT CAGAAACTTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Vegfb ( XM_006230910.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006230972.1 Rattus norvegicus vascular endothelial growth factor B (Vegfb), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa23844
Clone ID Related Accession (Same CDS sequence)	XM_006230910.3 , XM_006230911.3
Accession Version	XM_006230910.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 624bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	vascular endothelial growth factor B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006230910.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGCCCCC TGCTCCGTCG CTTGCTGCTT GTTGCGCTGC TGCAGCTGGC CTGTACCCAG 
GCCCCTGTGT CCCAGTTTGA TGGCCCCAGC CACCAGAAGA AAGTGGTGTC ATGGATAGAT 
GTTTATGCAC GTGCCACATG CCAGCCCAGG GAGGTGGTGG TACCTCTGAG CATGGAACTC 
ATGGGTAATG TGGTCAAACA ACTCGTGCCC AGCTGTGTGA CTGTGCAGCG CTGTGGTGGC 
TGCTGTCCTG ACGATGGCCT GGAGTGTGTG CCCATTGGGC AACACCAAGT CCGAATGCAG 
ATCCTCATGA TCCAGTACCC GAGCAGTCAG CTGGGGGAGA TGTCCCTGGA AGAACACAGC 
CAATGTGAAT GCAGACCAAA AAGAAAGGAG AGTGCTGTGA AGCCAGACAG GGTTGCCATA 
CCCCACCACC GTCCCCAGCC CCGCTCTGTT CTGAGCTGGG ACTCTGCCCC GGGAGCATCC 
TCCCCAGCTG ACATCATCCA TCCCACTCCA GCCCCAGGAC CCTCTGCCCA CGCTGCACCC 
AGCGCCGTCA GCGCCCTGAT CCCCGGACCT GCCGTTGCCG CTGCAGACGC CGCCGCTTCC 
TCCATTGCCA AGGGCGGGGC TTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006230972.1
CDS	398..1021
Translation	MSPLLRRLLLVALLQLACTQAPVSQFDGPSHQKKVVSWIDVYARATCQPREVVVPLSMELMGNVVKQLVPSCVTVQRCGGCCPDDGLECVPIGQHQVRMQILMIQYPSSQLGEMSLEEHSQCECRPKRKESAVKPDRVAIPHHRPQPRSVLSWDSAPGASSPADIIHPTPAPGPSAHAAPSAVSALIPGPAVAAADAAASSIAKGGA

Target ORF information:

RefSeq Version	XM_006230910.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus vascular endothelial growth factor B (Vegfb), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006230910.3

ORF Insert Sequence:

ATGAGCCCCC TGCTCCGTCG CTTGCTGCTT GTTGCGCTGC TGCAGCTGGC CTGTACCCAG 
GCCCCTGTGT CCCAGTTTGA TGGCCCCAGC CACCAGAAGA AAGTGGTGTC ATGGATAGAT 
GTTTATGCAC GTGCCACATG CCAGCCCAGG GAGGTGGTGG TACCTCTGAG CATGGAACTC 
ATGGGTAATG TGGTCAAACA ACTCGTGCCC AGCTGTGTGA CTGTGCAGCG CTGTGGTGGC 
TGCTGTCCTG ACGATGGCCT GGAGTGTGTG CCCATTGGGC AACACCAAGT CCGAATGCAG 
ATCCTCATGA TCCAGTACCC GAGCAGTCAG CTGGGGGAGA TGTCCCTGGA AGAACACAGC 
CAATGTGAAT GCAGACCAAA AAGAAAGGAG AGTGCTGTGA AGCCAGACAG GGTTGCCATA 
CCCCACCACC GTCCCCAGCC CCGCTCTGTT CTGAGCTGGG ACTCTGCCCC GGGAGCATCC 
TCCCCAGCTG ACATCATCCA TCCCACTCCA GCCCCAGGAC CCTCTGCCCA CGCTGCACCC 
AGCGCCGTCA GCGCCCTGAT CCCCGGACCT GCCGTTGCCG CTGCAGACGC CGCCGCTTCC 
TCCATTGCCA AGGGCGGGGC TTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Vegfb ( XM_006230911.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006230973.1 Rattus norvegicus vascular endothelial growth factor B (Vegfb), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa23844
Clone ID Related Accession (Same CDS sequence)	XM_006230910.3 , XM_006230911.3
Accession Version	XM_006230911.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 624bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	vascular endothelial growth factor B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006230911.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGCCCCC TGCTCCGTCG CTTGCTGCTT GTTGCGCTGC TGCAGCTGGC CTGTACCCAG 
GCCCCTGTGT CCCAGTTTGA TGGCCCCAGC CACCAGAAGA AAGTGGTGTC ATGGATAGAT 
GTTTATGCAC GTGCCACATG CCAGCCCAGG GAGGTGGTGG TACCTCTGAG CATGGAACTC 
ATGGGTAATG TGGTCAAACA ACTCGTGCCC AGCTGTGTGA CTGTGCAGCG CTGTGGTGGC 
TGCTGTCCTG ACGATGGCCT GGAGTGTGTG CCCATTGGGC AACACCAAGT CCGAATGCAG 
ATCCTCATGA TCCAGTACCC GAGCAGTCAG CTGGGGGAGA TGTCCCTGGA AGAACACAGC 
CAATGTGAAT GCAGACCAAA AAGAAAGGAG AGTGCTGTGA AGCCAGACAG GGTTGCCATA 
CCCCACCACC GTCCCCAGCC CCGCTCTGTT CTGAGCTGGG ACTCTGCCCC GGGAGCATCC 
TCCCCAGCTG ACATCATCCA TCCCACTCCA GCCCCAGGAC CCTCTGCCCA CGCTGCACCC 
AGCGCCGTCA GCGCCCTGAT CCCCGGACCT GCCGTTGCCG CTGCAGACGC CGCCGCTTCC 
TCCATTGCCA AGGGCGGGGC TTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006230973.1
CDS	398..1021
Translation	MSPLLRRLLLVALLQLACTQAPVSQFDGPSHQKKVVSWIDVYARATCQPREVVVPLSMELMGNVVKQLVPSCVTVQRCGGCCPDDGLECVPIGQHQVRMQILMIQYPSSQLGEMSLEEHSQCECRPKRKESAVKPDRVAIPHHRPQPRSVLSWDSAPGASSPADIIHPTPAPGPSAHAAPSAVSALIPGPAVAAADAAASSIAKGGA

Target ORF information:

RefSeq Version	XM_006230911.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus vascular endothelial growth factor B (Vegfb), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006230911.3

ORF Insert Sequence:

ATGAGCCCCC TGCTCCGTCG CTTGCTGCTT GTTGCGCTGC TGCAGCTGGC CTGTACCCAG 
GCCCCTGTGT CCCAGTTTGA TGGCCCCAGC CACCAGAAGA AAGTGGTGTC ATGGATAGAT 
GTTTATGCAC GTGCCACATG CCAGCCCAGG GAGGTGGTGG TACCTCTGAG CATGGAACTC 
ATGGGTAATG TGGTCAAACA ACTCGTGCCC AGCTGTGTGA CTGTGCAGCG CTGTGGTGGC 
TGCTGTCCTG ACGATGGCCT GGAGTGTGTG CCCATTGGGC AACACCAAGT CCGAATGCAG 
ATCCTCATGA TCCAGTACCC GAGCAGTCAG CTGGGGGAGA TGTCCCTGGA AGAACACAGC 
CAATGTGAAT GCAGACCAAA AAGAAAGGAG AGTGCTGTGA AGCCAGACAG GGTTGCCATA 
CCCCACCACC GTCCCCAGCC CCGCTCTGTT CTGAGCTGGG ACTCTGCCCC GGGAGCATCC 
TCCCCAGCTG ACATCATCCA TCCCACTCCA GCCCCAGGAC CCTCTGCCCA CGCTGCACCC 
AGCGCCGTCA GCGCCCTGAT CCCCGGACCT GCCGTTGCCG CTGCAGACGC CGCCGCTTCC 
TCCATTGCCA AGGGCGGGGC TTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Vegfb ( XM_006230912.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006230974.1 Rattus norvegicus vascular endothelial growth factor B (Vegfb), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa23845
Clone ID Related Accession (Same CDS sequence)	XM_006230912.3
Accession Version	XM_006230912.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 567bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	vascular endothelial growth factor B isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006230912.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGCCCCC TGCTCCGTCG CTTGCTGCTT GTTGCGCTGC TGCAGCTGGC CTGTACCCAG 
GCCCCTGTGT CCCAGTTTGA TGGCCCCAGC CACCAGAAGA AAGTGGTGTC ATGGATAGAT 
GTTTATGCAC GTGCCACATG CCAGCCCAGG GAGGTGGTGG TACCTCTGAG CATGGAACTC 
ATGGGTAATG TGGTCAAACA ACTCGTGCCC AGCTGTGTGA CTGTGCAGCG CTGTGGTGGC 
TGCTGTCCTG ACGATGGCCT GGAGTGTGTG CCCATTGGGC AACACCAAGT CCGAATGCAG 
ATCCTCATGA TCCAGTACCC GAGCAGTCAG CTGGGGGAGA TGTCCCTGGA AGAACACAGC 
CAATGTGAAT GCAGACCAAA AAGAAAGGAG AGTGCTGTGA AGCCAGACAG CCCCAGGACC 
CTCTGCCCAC GCTGCACCCA GCGCCGTCAG CGCCCTGATC CCCGGACCTG CCGTTGCCGC 
TGCAGACGCC GCCGCTTCCT CCATTGCCAA GGGCGGGGCT TAGAGCTCAA CCCAGATACC 
TGCAGGTGCC GGAAGCTGCG AAGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006230974.1
CDS	398..964
Translation	MSPLLRRLLLVALLQLACTQAPVSQFDGPSHQKKVVSWIDVYARATCQPREVVVPLSMELMGNVVKQLVPSCVTVQRCGGCCPDDGLECVPIGQHQVRMQILMIQYPSSQLGEMSLEEHSQCECRPKRKESAVKPDSPRTLCPRCTQRRQRPDPRTCRCRCRRRRFLHCQGRGLELNPDTCRCRKLRR

Target ORF information:

RefSeq Version	XM_006230912.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus vascular endothelial growth factor B (Vegfb), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006230912.3

ORF Insert Sequence:

ATGAGCCCCC TGCTCCGTCG CTTGCTGCTT GTTGCGCTGC TGCAGCTGGC CTGTACCCAG 
GCCCCTGTGT CCCAGTTTGA TGGCCCCAGC CACCAGAAGA AAGTGGTGTC ATGGATAGAT 
GTTTATGCAC GTGCCACATG CCAGCCCAGG GAGGTGGTGG TACCTCTGAG CATGGAACTC 
ATGGGTAATG TGGTCAAACA ACTCGTGCCC AGCTGTGTGA CTGTGCAGCG CTGTGGTGGC 
TGCTGTCCTG ACGATGGCCT GGAGTGTGTG CCCATTGGGC AACACCAAGT CCGAATGCAG 
ATCCTCATGA TCCAGTACCC GAGCAGTCAG CTGGGGGAGA TGTCCCTGGA AGAACACAGC 
CAATGTGAAT GCAGACCAAA AAGAAAGGAG AGTGCTGTGA AGCCAGACAG CCCCAGGACC 
CTCTGCCCAC GCTGCACCCA GCGCCGTCAG CGCCCTGATC CCCGGACCTG CCGTTGCCGC 
TGCAGACGCC GCCGCTTCCT CCATTGCCAA GGGCGGGGCT TAGAGCTCAA CCCAGATACC 
TGCAGGTGCC GGAAGCTGCG AAGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Loss of VEGFB and its signaling in the diabetic heart is associated with increased cell death signaling.
American journal of physiology. Heart and circulatory physiology312(6)H1163-H1175(2017 Jun)
Lal N,Chiu AP,Wang F,Zhang D,Jia J,Wan A,Vlodavsky I,Hussein B,Rodrigues B

Methylation patterns of Vegfb promoter are associated with gene and protein expression levels: the effects of dietary fatty acids.
European journal of nutrition56(2)715-726(2017 Mar)
Monastero R,Garc?a-Serrano S,Lago-Sampedro A,Rodr?guez-Pacheco F,Colomo N,Morcillo S,Mart?n-Nu?ez GM,Gomez-Zumaquero JM,Garc?a-Fuentes E,Soriguer F,Rojo-Mart?nez G,Garc?a-Escobar E

Oral Platelet-Derived Growth Factor and Vascular Endothelial Growth Factor Inhibitor Sunitinib Prevents Chronic Allograft Injury in Experimental Kidney Transplantation Model.
Transplantation100(1)103-10(2016 Jan)
Rintala JM,Savikko J,Palin N,Rintala SE,Koskinen PK,von Willebrand E

Vascular endothelial growth factor B prevents the shift in the ocular dominance distribution of visual cortical neurons in monocularly deprived rats.
Experimental eye research10917-21(2013 Apr)
Shan L,Yong H,Song Q,Wei Y,Qin R,Zhang G,Xu M,Zhang S

Cardiac VEGF-B expression decreases along with cardiac allograft unload.
Journal of cardiac failure18(11)879-80(2012 Nov)
Raissadati A,Tuuminen R

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Vegfb cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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