Ciita cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ciita
Entrez Gene ID	85483
Full Name	class II, major histocompatibility complex, transactivator
Synonyms	C2ta,Mhc2ta
General protein information	Preferred Names class II, major histocompatibility complex, transactivator Names MHC class II transactivator MHC class II transactivator type IV class II transactivator
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 10 Map Location: 10q11
Summary	may play a role in transcriptional activation of MHC class II genes [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001270803.1	NP_001257732.1	MHC class II transactivator isoform 2
NM_053529.2	NP_445981.2	MHC class II transactivator isoform 1
XM_006245738.3	XP_006245800.1	MHC class II transactivator isoform X1
XM_008767501.2	XP_008765723.1	MHC class II transactivator isoform X2
NM_001270804.1	NP_001257733.1	MHC class II transactivator isoform 3

Pathways from BioSystems

Homologies

Bos taurus (cattle)	CIITA	XP_002698008.2
	CIITA	XP_001103518.2
Canis lupus familiaris (dog)	CIITA	XP_005621604.1
Gallus gallus (chicken)	LOC416633	XP_004945372.1
Xenopus tropicalis (tropical clawed frog)	ciita	XP_004918329.1
Pan troglodytes (chimpanzee)	CIITA	XP_510813.2
Rattus norvegicus (Norway rat)	Ciita	NP_445981.2
Homo sapiens (human)	CIITA	NP_001273331.1
Mus musculus (house mouse)	Ciita	NP_001230689.1
Danio rerio (zebrafish)	ciita	XP_005163972.1

Gene Ontology
Bibliography

Related articles in PubMed

Allelic difference in Mhc2ta confers altered microglial activation and susceptibility to ?-synuclein-induced dopaminergic neurodegeneration.
Jimenez-Ferrer I, Jewett M, Tontanahal A, Romero-Ramos M, Swanberg M
Neurobiology of disease106279-290(2017 Oct)

Downregulating immunogenicity of Schwann cells via inhibiting a potential target of class II transactivator (CIITA) gene.
Yang Y, Dai W, Chen Z, Yan Z, Yao Z, Zhang C
Bioscience trends7(1)50-5(2013 Feb)

PML promotes MHC class II gene expression by stabilizing the class II transactivator.
Ulbricht T, Alzrigat M, Horch A, Reuter N, von Mikecz A, Steimle V, Schmitt E, Kr?mer OH, Stamminger T, Hemmerich P
The Journal of cell biology199(1)49-63(2012 Oct)

Interrogating the complex role of chromosome 16p13.13 in multiple sclerosis susceptibility: independent genetic signals in the CIITA-CLEC16A-SOCS1 gene complex.
Zuvich RL, Bush WS, McCauley JL, Beecham AH, De Jager PL, , Ivinson AJ, Compston A, Hafler DA, Hauser SL, Sawcer SJ, Pericak-Vance MA, Barcellos LF, Mortlock DP, Haines JL
Human molecular genetics20(17)3517-24(2011 Sep)

NLR family member NLRC5 is a transcriptional regulator of MHC class I genes.
Meissner TB, Li A, Biswas A, Lee KH, Liu YJ, Bayir E, Iliopoulos D, van den Elsen PJ, Kobayashi KS
Proceedings of the National Academy of Sciences of the United States of America107(31)13794-9(2010 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Naturally occurring allelic variability in Mhc2ta profoundly affects the quantity of class II histocompatibility gene expression in the central nervous system and modulates susceptibility to autoimmune neuroinflammation.
Title: Vra4 congenic rats with allelic differences in the class II transactivator gene display altered susceptibility to experimental autoimmune encephalomyelitis.

mutations result in differential MHC molecule expression associated with susceptibility to inflammatory diseases
Title: MHC2TA is associated with differential MHC molecule expression and susceptibility to rheumatoid arthritis, multiple sclerosis and myocardial infarction.

Silencing of CIITA transcription is recessive in trophoblasts and involves an epigenetic mechanism other than promoter methylation. Trophoblasts may be missing a factor that regulates chromatin structure at the CIITA promoter.
Title: Class II transactivator (CIITA) promoter methylation does not correlate with silencing of CIITA transcription in trophoblasts.

possible role in IFN-gamma induction of MHC class II
Title: Failure of MHC class II expression in neonatal alveolar macrophages: potential role of class II transactivator.

The following Ciita gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ciita cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa09812	NM_053529.2 Latest version!	Rattus norvegicus class II, major histocompatibility complex, transactivator (Ciita), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$559.30 $799.00
ORa09833	NM_001270803.1 Latest version!	Rattus norvegicus class II, major histocompatibility complex, transactivator (Ciita), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$559.30 $799.00
ORa09836	NM_001270804.1 Latest version!	Rattus norvegicus class II, major histocompatibility complex, transactivator (Ciita), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$559.30 $799.00
ORa09812	XM_006245738.3 Latest version!	Rattus norvegicus class II, major histocompatibility complex, transactivator (Ciita), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$559.30 $799.00
ORa09836	XM_008767501.2 Latest version!	Rattus norvegicus class II, major histocompatibility complex, transactivator (Ciita), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$559.30 $799.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ciita ( NM_053529.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_445981.2 Rattus norvegicus class II, major histocompatibility complex, transactivator (Ciita), transcript variant 1, mRNA.

Price & Availability↑

CloneID	ORa09812
Clone ID Related Accession (Same CDS sequence)	NM_053529.2 , XM_006245738.3
Accession Version	NM_053529.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3462bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-20
Organism	Rattus norvegicus(Norway rat)
Product	MHC class II transactivator isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC103514.7. On Aug 2, 2012 this sequence version replaced NM_053529.1. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF251305.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAACCACT TCCAGGCCAT CCTGGCCCAG GTGCAGACAC TGCTGTCCAG TCAGCAGCCC 
AGGCAGGTGC GGGCCCTCCT GGATGGCTTG CTGGAAGAAG AGCTGCTCTC ACGGGAATAC 
CATTGTGCCC TGCTTCATGA GCCTGATGGT GAGGCTCTGG CCCGGAAGAT TTCCCTCACC 
TTGCTGGAGA AAGGGGACCT GGACTTGGCG TTTGTGAGCT GGGTTTGCAA CAGGCTGCAG 
GTCCCTGAGG TAGAGAGGGG CCCCAACTGC AGGGACCATG GAGGCCATAC TCTGTGTGCC 
ACCATGGAGC TGGGGTCTCC AGAGGGCAGC TACCTGGAGC TCCTTAACAG TGATGCTGAC 
CCCCTACACC TCTACCACCT CTATGACCAG ATGGACCTTG CTGGGGAGGA AGAGATCGAA 
CTCAACTCAG AGACAGACAT GGACACCATC AACTGTGACC AGTTCAGCAA GCTGTTGCAG 
GATATGGAAA TGGATGAAGA GACCCGGGAG GCCTATGCCA ATATCGCGGA ACTGGATCAG 
TACGTGTTCC AGGATACCCA GCTGGAGGGC CTGAGCAAGG ACCTCTTCAT ACAGCACATT 
GGACCAGAGG AAGGCTTTGG TGAGAACGTA GAGGGCCCTG CAGAATCAGG AGAGAAGCCT 
CAGAAGAGAC GCTTCCCAGA AGAGCATGCT ATGGACTCAA AGCACAGGAA ACTAGTGCCT 
CCCTCTAGGA CCTCACTGAA CTATTTGGAT CTCCCCGCTG GGCATATCCA GATCTTCACC 
ACTCTGCCCC AGGGACTCTG GCAAATCTCA GGGGTTGGCA CAGGGCTCTC CAGTGTCCTA 
GTCTACCACG GTGAGATGCC CCAGGTCAAC CAATTACTCT CTTCAAGCAG CCCCACTGTC 
CCCAGTCTCC CCGAGTCCCC AGACCGGCCT GGCTCCACCA GCCCCTTCGC GCCATCCACA 
GCTGACCTGC CCGGCATGCC TGAACCTGCT CTGACCTCCC GTGTAAATGA GACAGAGGAC 
ACAACACCCC CCTCCCCATG CCAAGAGGAT CCCGAGCCTT CCATCAAGCT TCCAAAATGG 
CCAGAGTCCG TGGAGCGGTT CCAGCACTCC CTACAGGACA AGTACCAAGC ACTGCCCGGG 
AGCCCAAGTG GTCCTCTGGT AGCCATGGAG CTGGTGCGGG CCAGGTTGGA AAGAGGTAGC 
AACAAGAGTC AGGAAAGGGA GCTGGCCACT CCTGACTGGA CAGAGCGCCA GCTAGCCCAT 
GGCGGTCTGG CCGAGGTACT TCGGGTTGTC GGCGACTCCA GGAGATCACG AGAGACACAG 
GTGGTCGCTG TGCTGGGCAA GGCTGGTCAG GGCAAGAGCC ACTGGGCCAG GACAGTGAGC 
CACATTTGGG CACAAGGCCA GTTACCACAA TATGACTTTG TCTTCTACGT CCCCTGTCAA 
TGCTTGGATC GCCCTGGGGA CACCTACCAC CTGCGGGATC TGCTCTGTCC CCCGAACCTG 
CAGCCACTGG CCATGGATGA CGAGGTCATT GATCATATTG TGAGGCAGCC GGACCGTGTT 
CTGCTCATCC TAGATGCTTT TGAGGAGCTA GAGGCCCAAG ACAGCCTCCT GCATGGACCC 
TGTGGACCTC TGTCCCCAGA GCCCTGCTCC CTCCGGGGAC TGCTGGCTGG GCTCTTCCAG 
CGTAAGCTGC TGCGAGGCTG CACCCTGCTC CTCACAGCCC GGCCCCGGGG CCGCCTGGCT 
CAGAGCCTGA GCAAGGCAGA TGCCATCTTC GAGGTGCCCA GCTTCTCTAC GAAACAGGCC 
CAGATCTATA TGAGGCACTA CTTTGAGAAC TCAGGGACAG CAGGGAGTCA CGACAAGGCC 
CTGGGCCTCC TGGAGGGCCA GCCTTTTCTC CTCACCCACA GTCACAGCCC TGTTCTGTGC 
AGTGCCGTGT GTCAGCTCTC CAAGGCCCTG CTGGATCAGG GCGCAGAGGC CCAGCTACCT 
TGCACACTCA CAGGACTCTA TGTTGGCCTG CTAGGCCCTG CAGCTCAGAA CAGTCCTCCT 
GGAGCCTTAG TTGAGTTGGC CAAGCTAGCC TGGGAGCTGG GACGGAGGCA CCAAAGCACC 
TTGCAGGAAA CCCAGTTTCC ATCCGTGGAA GTGAAGACCT GGGCTGTGGC CCAAGGCTTG 
ATGCAGCAGA CCACAGAGGC CCAACTGGCT TTCTCCAGTT TTCTGCTACA GTGCTTCCTG 
GGTGCTGTGT GGCTGGCACA GTGCAATGAG ATGAAAGACA AGGAGCTGCC ACAGTACCTG 
GCCTTGACCC CGAGGAAGAA GCGACCCTAT GACAACTGGC TGGAGGGCGT ACCACGCTTT 
CTGGCTGGCT TAGTTTTCCA GCCTCGAGCC CACTGCCTGG GAGCTCTGGT GGAGCCTGCA 
ATGGCTGCAG TGGCAGATAG GAAACGGAAG GTTCTTACCA GGTACCTGAA GCGCTTGAAG 
CTGGGGACAC TTCGGGCCGG GAGGTTGCTG GAGCTGCTAC ACTGTGCCCA CGAAACACAG 
GAACCTGGTA TTTGGAAGCA TGTTTCACAC CAGCTCCCAG GGCACCTCTC CTTCCTGGGC 
ACACGGCTCA CAGCCCCAGA TGTGTATGTT CTGGGCAGGG CCTTGGAGAC AGCCAGCCAG 
GACTTCTCCT TGGACCTTCG TCAGACTGGC ATCGAGCCCT CCAGACTGGG AGACCTCGTG 
GGACTCAGCT GTGTCACCAG TTTCAGGGCC TCCTTGAGTG ACACAATGGC ATTATGGGAG 
TCCCTACAGC ATCAGGGAGA AACCCAGCTA CTCCAGGCGG CAGAGGAGAA GTTCACCATT 
GAGCCATTTA AGGCCAAATC CCCAAAGGAT GTGGAAGACC TGGACAGCCT TGTGCAGACC 
CAGAGGCTGA GAAACCCCTC AGCGGATGCA GCCAAGGATC TTCCTGCCAT CCGGGACCTT 
AAGAAGCTAG AGTTTGCATT GGGCCCCGTC TTGGGCCCGC AGGCTTTCCC CACACTGGCC 
AAGATCCTTC CAGCATTCTC TTCCCTGCAG CACCTGGACC TGGACTCACT TAGCGAGAAC 
AAGATCGGGG ACAAGGGTGT GTCGAAGCTC TCAGCCACCT TCCCTCAGCT GAAGGCCCTG 
GAGACGCTCA ACCTGTCCCA GAATAGCATC ACCGATGTGG GAGCTTGCAA GCTTGCAGAA 
GCCCTGCCGG CCCTGGCCAA GTCCCTCCTA AGGCTGAGCT TGTACAACAA CTGCATCTGT 
GACGAAGGGG CCAAGAGCCT GGCACGAGTG CTTCCAGACA TGGTGTCCCT CCGGGTGATG 
GATGTCCAGT TCAACAAGTT CACGGCTGTC GGGGCCCAGC AGCTGACCTC CAGCCTTCAG 
AAGTGCCCTC AGGTGGAGAC ACTGGCAATG TGGACACCCA CTATCCCCTT TGGGGTCCAG 
GAACACCTGC AGCAGCTGGA TGCCCGGATT AGCCTGAGAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_445981.2
CDS	83..3544
Translation	MNHFQAILAQVQTLLSSQQPRQVRALLDGLLEEELLSREYHCALLHEPDGEALARKISLTLLEKGDLDLAFVSWVCNRLQVPEVERGPNCRDHGGHTLCATMELGSPEGSYLELLNSDADPLHLYHLYDQMDLAGEEEIELNSETDMDTINCDQFSKLLQDMEMDEETREAYANIAELDQYVFQDTQLEGLSKDLFIQHIGPEEGFGENVEGPAESGEKPQKRRFPEEHAMDSKHRKLVPPSRTSLNYLDLPAGHIQIFTTLPQGLWQISGVGTGLSSVLVYHGEMPQVNQLLSSSSPTVPSLPESPDRPGSTSPFAPSTADLPGMPEPALTSRVNETEDTTPPSPCQEDPEPSIKLPKWPESVERFQHSLQDKYQALPGSPSGPLVAMELVRARLERGSNKSQERELATPDWTERQLAHGGLAEVLRVVGDSRRSRETQVVAVLGKAGQGKSHWARTVSHIWAQGQLPQYDFVFYVPCQCLDRPGDTYHLRDLLCPPNLQPLAMDDEVIDHIVRQPDRVLLILDAFEELEAQDSLLHGPCGPLSPEPCSLRGLLAGLFQRKLLRGCTLLLTARPRGRLAQSLSKADAIFEVPSFSTKQAQIYMRHYFENSGTAGSHDKALGLLEGQPFLLTHSHSPVLCSAVCQLSKALLDQGAEAQLPCTLTGLYVGLLGPAAQNSPPGALVELAKLAWELGRRHQSTLQETQFPSVEVKTWAVAQGLMQQTTEAQLAFSSFLLQCFLGAVWLAQCNEMKDKELPQYLALTPRKKRPYDNWLEGVPRFLAGLVFQPRAHCLGALVEPAMAAVADRKRKVLTRYLKRLKLGTLRAGRLLELLHCAHETQEPGIWKHVSHQLPGHLSFLGTRLTAPDVYVLGRALETASQDFSLDLRQTGIEPSRLGDLVGLSCVTSFRASLSDTMALWESLQHQGETQLLQAAEEKFTIEPFKAKSPKDVEDLDSLVQTQRLRNPSADAAKDLPAIRDLKKLEFALGPVLGPQAFPTLAKILPAFSSLQHLDLDSLSENKIGDKGVSKLSATFPQLKALETLNLSQNSITDVGACKLAEALPALAKSLLRLSLYNNCICDEGAKSLARVLPDMVSLRVMDVQFNKFTAVGAQQLTSSLQKCPQVETLAMWTPTIPFGVQEHLQQLDARISLR

Target ORF information:

RefSeq Version	NM_053529.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus class II, major histocompatibility complex, transactivator (Ciita), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_053529.2

ORF Insert Sequence:

ATGAACCACT TCCAGGCCAT CCTGGCCCAG GTGCAGACAC TGCTGTCCAG TCAGCAGCCC 
AGGCAGGTGC GGGCCCTCCT GGATGGCTTG CTGGAAGAAG AGCTGCTCTC ACGGGAATAC 
CATTGTGCCC TGCTTCATGA GCCTGATGGT GAGGCTCTGG CCCGGAAGAT TTCCCTCACC 
TTGCTGGAGA AAGGGGACCT GGACTTGGCG TTTGTGAGCT GGGTTTGCAA CAGGCTGCAG 
GTCCCTGAGG TAGAGAGGGG CCCCAACTGC AGGGACCATG GAGGCCATAC TCTGTGTGCC 
ACCATGGAGC TGGGGTCTCC AGAGGGCAGC TACCTGGAGC TCCTTAACAG TGATGCTGAC 
CCCCTACACC TCTACCACCT CTATGACCAG ATGGACCTTG CTGGGGAGGA AGAGATCGAA 
CTCAACTCAG AGACAGACAT GGACACCATC AACTGTGACC AGTTCAGCAA GCTGTTGCAG 
GATATGGAAA TGGATGAAGA GACCCGGGAG GCCTATGCCA ATATCGCGGA ACTGGATCAG 
TACGTGTTCC AGGATACCCA GCTGGAGGGC CTGAGCAAGG ACCTCTTCAT ACAGCACATT 
GGACCAGAGG AAGGCTTTGG TGAGAACGTA GAGGGCCCTG CAGAATCAGG AGAGAAGCCT 
CAGAAGAGAC GCTTCCCAGA AGAGCATGCT ATGGACTCAA AGCACAGGAA ACTAGTGCCT 
CCCTCTAGGA CCTCACTGAA CTATTTGGAT CTCCCCGCTG GGCATATCCA GATCTTCACC 
ACTCTGCCCC AGGGACTCTG GCAAATCTCA GGGGTTGGCA CAGGGCTCTC CAGTGTCCTA 
GTCTACCACG GTGAGATGCC CCAGGTCAAC CAATTACTCT CTTCAAGCAG CCCCACTGTC 
CCCAGTCTCC CCGAGTCCCC AGACCGGCCT GGCTCCACCA GCCCCTTCGC GCCATCCACA 
GCTGACCTGC CCGGCATGCC TGAACCTGCT CTGACCTCCC GTGTAAATGA GACAGAGGAC 
ACAACACCCC CCTCCCCATG CCAAGAGGAT CCCGAGCCTT CCATCAAGCT TCCAAAATGG 
CCAGAGTCCG TGGAGCGGTT CCAGCACTCC CTACAGGACA AGTACCAAGC ACTGCCCGGG 
AGCCCAAGTG GTCCTCTGGT AGCCATGGAG CTGGTGCGGG CCAGGTTGGA AAGAGGTAGC 
AACAAGAGTC AGGAAAGGGA GCTGGCCACT CCTGACTGGA CAGAGCGCCA GCTAGCCCAT 
GGCGGTCTGG CCGAGGTACT TCGGGTTGTC GGCGACTCCA GGAGATCACG AGAGACACAG 
GTGGTCGCTG TGCTGGGCAA GGCTGGTCAG GGCAAGAGCC ACTGGGCCAG GACAGTGAGC 
CACATTTGGG CACAAGGCCA GTTACCACAA TATGACTTTG TCTTCTACGT CCCCTGTCAA 
TGCTTGGATC GCCCTGGGGA CACCTACCAC CTGCGGGATC TGCTCTGTCC CCCGAACCTG 
CAGCCACTGG CCATGGATGA CGAGGTCATT GATCATATTG TGAGGCAGCC GGACCGTGTT 
CTGCTCATCC TAGATGCTTT TGAGGAGCTA GAGGCCCAAG ACAGCCTCCT GCATGGACCC 
TGTGGACCTC TGTCCCCAGA GCCCTGCTCC CTCCGGGGAC TGCTGGCTGG GCTCTTCCAG 
CGTAAGCTGC TGCGAGGCTG CACCCTGCTC CTCACAGCCC GGCCCCGGGG CCGCCTGGCT 
CAGAGCCTGA GCAAGGCAGA TGCCATCTTC GAGGTGCCCA GCTTCTCTAC GAAACAGGCC 
CAGATCTATA TGAGGCACTA CTTTGAGAAC TCAGGGACAG CAGGGAGTCA CGACAAGGCC 
CTGGGCCTCC TGGAGGGCCA GCCTTTTCTC CTCACCCACA GTCACAGCCC TGTTCTGTGC 
AGTGCCGTGT GTCAGCTCTC CAAGGCCCTG CTGGATCAGG GCGCAGAGGC CCAGCTACCT 
TGCACACTCA CAGGACTCTA TGTTGGCCTG CTAGGCCCTG CAGCTCAGAA CAGTCCTCCT 
GGAGCCTTAG TTGAGTTGGC CAAGCTAGCC TGGGAGCTGG GACGGAGGCA CCAAAGCACC 
TTGCAGGAAA CCCAGTTTCC ATCCGTGGAA GTGAAGACCT GGGCTGTGGC CCAAGGCTTG 
ATGCAGCAGA CCACAGAGGC CCAACTGGCT TTCTCCAGTT TTCTGCTACA GTGCTTCCTG 
GGTGCTGTGT GGCTGGCACA GTGCAATGAG ATGAAAGACA AGGAGCTGCC ACAGTACCTG 
GCCTTGACCC CGAGGAAGAA GCGACCCTAT GACAACTGGC TGGAGGGCGT ACCACGCTTT 
CTGGCTGGCT TAGTTTTCCA GCCTCGAGCC CACTGCCTGG GAGCTCTGGT GGAGCCTGCA 
ATGGCTGCAG TGGCAGATAG GAAACGGAAG GTTCTTACCA GGTACCTGAA GCGCTTGAAG 
CTGGGGACAC TTCGGGCCGG GAGGTTGCTG GAGCTGCTAC ACTGTGCCCA CGAAACACAG 
GAACCTGGTA TTTGGAAGCA TGTTTCACAC CAGCTCCCAG GGCACCTCTC CTTCCTGGGC 
ACACGGCTCA CAGCCCCAGA TGTGTATGTT CTGGGCAGGG CCTTGGAGAC AGCCAGCCAG 
GACTTCTCCT TGGACCTTCG TCAGACTGGC ATCGAGCCCT CCAGACTGGG AGACCTCGTG 
GGACTCAGCT GTGTCACCAG TTTCAGGGCC TCCTTGAGTG ACACAATGGC ATTATGGGAG 
TCCCTACAGC ATCAGGGAGA AACCCAGCTA CTCCAGGCGG CAGAGGAGAA GTTCACCATT 
GAGCCATTTA AGGCCAAATC CCCAAAGGAT GTGGAAGACC TGGACAGCCT TGTGCAGACC 
CAGAGGCTGA GAAACCCCTC AGCGGATGCA GCCAAGGATC TTCCTGCCAT CCGGGACCTT 
AAGAAGCTAG AGTTTGCATT GGGCCCCGTC TTGGGCCCGC AGGCTTTCCC CACACTGGCC 
AAGATCCTTC CAGCATTCTC TTCCCTGCAG CACCTGGACC TGGACTCACT TAGCGAGAAC 
AAGATCGGGG ACAAGGGTGT GTCGAAGCTC TCAGCCACCT TCCCTCAGCT GAAGGCCCTG 
GAGACGCTCA ACCTGTCCCA GAATAGCATC ACCGATGTGG GAGCTTGCAA GCTTGCAGAA 
GCCCTGCCGG CCCTGGCCAA GTCCCTCCTA AGGCTGAGCT TGTACAACAA CTGCATCTGT 
GACGAAGGGG CCAAGAGCCT GGCACGAGTG CTTCCAGACA TGGTGTCCCT CCGGGTGATG 
GATGTCCAGT TCAACAAGTT CACGGCTGTC GGGGCCCAGC AGCTGACCTC CAGCCTTCAG 
AAGTGCCCTC AGGTGGAGAC ACTGGCAATG TGGACACCCA CTATCCCCTT TGGGGTCCAG 
GAACACCTGC AGCAGCTGGA TGCCCGGATT AGCCTGAGAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ciita ( NM_001270803.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001257732.1 Rattus norvegicus class II, major histocompatibility complex, transactivator (Ciita), transcript variant 2, mRNA.

Price & Availability↑

CloneID	ORa09833
Clone ID Related Accession (Same CDS sequence)	NM_001270803.1
Accession Version	NM_001270803.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3222bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-20
Organism	Rattus norvegicus(Norway rat)
Product	MHC class II transactivator isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC103514.7. Transcript Variant: This variant (2) has an alternate first exon compared to variant 1. The resulting isoform (2) has a shorter and distinct N-terminus compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF251306.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCGCTGCC AGGTTCCCGG CCCTTCTGGG TCTTACCTGC AAGGCCATAC TCTGTGTGCC 
ACCATGGAGC TGGGGTCTCC AGAGGGCAGC TACCTGGAGC TCCTTAACAG TGATGCTGAC 
CCCCTACACC TCTACCACCT CTATGACCAG ATGGACCTTG CTGGGGAGGA AGAGATCGAA 
CTCAACTCAG AGACAGACAT GGACACCATC AACTGTGACC AGTTCAGCAA GCTGTTGCAG 
GATATGGAAA TGGATGAAGA GACCCGGGAG GCCTATGCCA ATATCGCGGA ACTGGATCAG 
TACGTGTTCC AGGATACCCA GCTGGAGGGC CTGAGCAAGG ACCTCTTCAT ACAGCACATT 
GGACCAGAGG AAGGCTTTGG TGAGAACGTA GAGGGCCCTG CAGAATCAGG AGAGAAGCCT 
CAGAAGAGAC GCTTCCCAGA AGAGCATGCT ATGGACTCAA AGCACAGGAA ACTAGTGCCT 
CCCTCTAGGA CCTCACTGAA CTATTTGGAT CTCCCCGCTG GGCATATCCA GATCTTCACC 
ACTCTGCCCC AGGGACTCTG GCAAATCTCA GGGGTTGGCA CAGGGCTCTC CAGTGTCCTA 
GTCTACCACG GTGAGATGCC CCAGGTCAAC CAATTACTCT CTTCAAGCAG CCCCACTGTC 
CCCAGTCTCC CCGAGTCCCC AGACCGGCCT GGCTCCACCA GCCCCTTCGC GCCATCCACA 
GCTGACCTGC CCGGCATGCC TGAACCTGCT CTGACCTCCC GTGTAAATGA GACAGAGGAC 
ACAACACCCC CCTCCCCATG CCAAGAGGAT CCCGAGCCTT CCATCAAGCT TCCAAAATGG 
CCAGAGTCCG TGGAGCGGTT CCAGCACTCC CTACAGGACA AGTACCAAGC ACTGCCCGGG 
AGCCCAAGTG GTCCTCTGGT AGCCATGGAG CTGGTGCGGG CCAGGTTGGA AAGAGGTAGC 
AACAAGAGTC AGGAAAGGGA GCTGGCCACT CCTGACTGGA CAGAGCGCCA GCTAGCCCAT 
GGCGGTCTGG CCGAGGTACT TCGGGTTGTC GGCGACTCCA GGAGATCACG AGAGACACAG 
GTGGTCGCTG TGCTGGGCAA GGCTGGTCAG GGCAAGAGCC ACTGGGCCAG GACAGTGAGC 
CACATTTGGG CACAAGGCCA GTTACCACAA TATGACTTTG TCTTCTACGT CCCCTGTCAA 
TGCTTGGATC GCCCTGGGGA CACCTACCAC CTGCGGGATC TGCTCTGTCC CCCGAACCTG 
CAGCCACTGG CCATGGATGA CGAGGTCATT GATCATATTG TGAGGCAGCC GGACCGTGTT 
CTGCTCATCC TAGATGCTTT TGAGGAGCTA GAGGCCCAAG ACAGCCTCCT GCATGGACCC 
TGTGGACCTC TGTCCCCAGA GCCCTGCTCC CTCCGGGGAC TGCTGGCTGG GCTCTTCCAG 
CGTAAGCTGC TGCGAGGCTG CACCCTGCTC CTCACAGCCC GGCCCCGGGG CCGCCTGGCT 
CAGAGCCTGA GCAAGGCAGA TGCCATCTTC GAGGTGCCCA GCTTCTCTAC GAAACAGGCC 
CAGATCTATA TGAGGCACTA CTTTGAGAAC TCAGGGACAG CAGGGAGTCA CGACAAGGCC 
CTGGGCCTCC TGGAGGGCCA GCCTTTTCTC CTCACCCACA GTCACAGCCC TGTTCTGTGC 
AGTGCCGTGT GTCAGCTCTC CAAGGCCCTG CTGGATCAGG GCGCAGAGGC CCAGCTACCT 
TGCACACTCA CAGGACTCTA TGTTGGCCTG CTAGGCCCTG CAGCTCAGAA CAGTCCTCCT 
GGAGCCTTAG TTGAGTTGGC CAAGCTAGCC TGGGAGCTGG GACGGAGGCA CCAAAGCACC 
TTGCAGGAAA CCCAGTTTCC ATCCGTGGAA GTGAAGACCT GGGCTGTGGC CCAAGGCTTG 
ATGCAGCAGA CCACAGAGGC CCAACTGGCT TTCTCCAGTT TTCTGCTACA GTGCTTCCTG 
GGTGCTGTGT GGCTGGCACA GTGCAATGAG ATGAAAGACA AGGAGCTGCC ACAGTACCTG 
GCCTTGACCC CGAGGAAGAA GCGACCCTAT GACAACTGGC TGGAGGGCGT ACCACGCTTT 
CTGGCTGGCT TAGTTTTCCA GCCTCGAGCC CACTGCCTGG GAGCTCTGGT GGAGCCTGCA 
ATGGCTGCAG TGGCAGATAG GAAACGGAAG GTTCTTACCA GGTACCTGAA GCGCTTGAAG 
CTGGGGACAC TTCGGGCCGG GAGGTTGCTG GAGCTGCTAC ACTGTGCCCA CGAAACACAG 
GAACCTGGTA TTTGGAAGCA TGTTTCACAC CAGCTCCCAG GGCACCTCTC CTTCCTGGGC 
ACACGGCTCA CAGCCCCAGA TGTGTATGTT CTGGGCAGGG CCTTGGAGAC AGCCAGCCAG 
GACTTCTCCT TGGACCTTCG TCAGACTGGC ATCGAGCCCT CCAGACTGGG AGACCTCGTG 
GGACTCAGCT GTGTCACCAG TTTCAGGGCC TCCTTGAGTG ACACAATGGC ATTATGGGAG 
TCCCTACAGC ATCAGGGAGA AACCCAGCTA CTCCAGGCGG CAGAGGAGAA GTTCACCATT 
GAGCCATTTA AGGCCAAATC CCCAAAGGAT GTGGAAGACC TGGACAGCCT TGTGCAGACC 
CAGAGGCTGA GAAACCCCTC AGCGGATGCA GCCAAGGATC TTCCTGCCAT CCGGGACCTT 
AAGAAGCTAG AGTTTGCATT GGGCCCCGTC TTGGGCCCGC AGGCTTTCCC CACACTGGCC 
AAGATCCTTC CAGCATTCTC TTCCCTGCAG CACCTGGACC TGGACTCACT TAGCGAGAAC 
AAGATCGGGG ACAAGGGTGT GTCGAAGCTC TCAGCCACCT TCCCTCAGCT GAAGGCCCTG 
GAGACGCTCA ACCTGTCCCA GAATAGCATC ACCGATGTGG GAGCTTGCAA GCTTGCAGAA 
GCCCTGCCGG CCCTGGCCAA GTCCCTCCTA AGGCTGAGCT TGTACAACAA CTGCATCTGT 
GACGAAGGGG CCAAGAGCCT GGCACGAGTG CTTCCAGACA TGGTGTCCCT CCGGGTGATG 
GATGTCCAGT TCAACAAGTT CACGGCTGTC GGGGCCCAGC AGCTGACCTC CAGCCTTCAG 
AAGTGCCCTC AGGTGGAGAC ACTGGCAATG TGGACACCCA CTATCCCCTT TGGGGTCCAG 
GAACACCTGC AGCAGCTGGA TGCCCGGATT AGCCTGAGAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001257732.1
CDS	104..3325
Translation	MRCQVPGPSGSYLQGHTLCATMELGSPEGSYLELLNSDADPLHLYHLYDQMDLAGEEEIELNSETDMDTINCDQFSKLLQDMEMDEETREAYANIAELDQYVFQDTQLEGLSKDLFIQHIGPEEGFGENVEGPAESGEKPQKRRFPEEHAMDSKHRKLVPPSRTSLNYLDLPAGHIQIFTTLPQGLWQISGVGTGLSSVLVYHGEMPQVNQLLSSSSPTVPSLPESPDRPGSTSPFAPSTADLPGMPEPALTSRVNETEDTTPPSPCQEDPEPSIKLPKWPESVERFQHSLQDKYQALPGSPSGPLVAMELVRARLERGSNKSQERELATPDWTERQLAHGGLAEVLRVVGDSRRSRETQVVAVLGKAGQGKSHWARTVSHIWAQGQLPQYDFVFYVPCQCLDRPGDTYHLRDLLCPPNLQPLAMDDEVIDHIVRQPDRVLLILDAFEELEAQDSLLHGPCGPLSPEPCSLRGLLAGLFQRKLLRGCTLLLTARPRGRLAQSLSKADAIFEVPSFSTKQAQIYMRHYFENSGTAGSHDKALGLLEGQPFLLTHSHSPVLCSAVCQLSKALLDQGAEAQLPCTLTGLYVGLLGPAAQNSPPGALVELAKLAWELGRRHQSTLQETQFPSVEVKTWAVAQGLMQQTTEAQLAFSSFLLQCFLGAVWLAQCNEMKDKELPQYLALTPRKKRPYDNWLEGVPRFLAGLVFQPRAHCLGALVEPAMAAVADRKRKVLTRYLKRLKLGTLRAGRLLELLHCAHETQEPGIWKHVSHQLPGHLSFLGTRLTAPDVYVLGRALETASQDFSLDLRQTGIEPSRLGDLVGLSCVTSFRASLSDTMALWESLQHQGETQLLQAAEEKFTIEPFKAKSPKDVEDLDSLVQTQRLRNPSADAAKDLPAIRDLKKLEFALGPVLGPQAFPTLAKILPAFSSLQHLDLDSLSENKIGDKGVSKLSATFPQLKALETLNLSQNSITDVGACKLAEALPALAKSLLRLSLYNNCICDEGAKSLARVLPDMVSLRVMDVQFNKFTAVGAQQLTSSLQKCPQVETLAMWTPTIPFGVQEHLQQLDARISLR

Target ORF information:

RefSeq Version	NM_001270803.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus class II, major histocompatibility complex, transactivator (Ciita), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001270803.1

ORF Insert Sequence:

ATGCGCTGCC AGGTTCCCGG CCCTTCTGGG TCTTACCTGC AAGGCCATAC TCTGTGTGCC 
ACCATGGAGC TGGGGTCTCC AGAGGGCAGC TACCTGGAGC TCCTTAACAG TGATGCTGAC 
CCCCTACACC TCTACCACCT CTATGACCAG ATGGACCTTG CTGGGGAGGA AGAGATCGAA 
CTCAACTCAG AGACAGACAT GGACACCATC AACTGTGACC AGTTCAGCAA GCTGTTGCAG 
GATATGGAAA TGGATGAAGA GACCCGGGAG GCCTATGCCA ATATCGCGGA ACTGGATCAG 
TACGTGTTCC AGGATACCCA GCTGGAGGGC CTGAGCAAGG ACCTCTTCAT ACAGCACATT 
GGACCAGAGG AAGGCTTTGG TGAGAACGTA GAGGGCCCTG CAGAATCAGG AGAGAAGCCT 
CAGAAGAGAC GCTTCCCAGA AGAGCATGCT ATGGACTCAA AGCACAGGAA ACTAGTGCCT 
CCCTCTAGGA CCTCACTGAA CTATTTGGAT CTCCCCGCTG GGCATATCCA GATCTTCACC 
ACTCTGCCCC AGGGACTCTG GCAAATCTCA GGGGTTGGCA CAGGGCTCTC CAGTGTCCTA 
GTCTACCACG GTGAGATGCC CCAGGTCAAC CAATTACTCT CTTCAAGCAG CCCCACTGTC 
CCCAGTCTCC CCGAGTCCCC AGACCGGCCT GGCTCCACCA GCCCCTTCGC GCCATCCACA 
GCTGACCTGC CCGGCATGCC TGAACCTGCT CTGACCTCCC GTGTAAATGA GACAGAGGAC 
ACAACACCCC CCTCCCCATG CCAAGAGGAT CCCGAGCCTT CCATCAAGCT TCCAAAATGG 
CCAGAGTCCG TGGAGCGGTT CCAGCACTCC CTACAGGACA AGTACCAAGC ACTGCCCGGG 
AGCCCAAGTG GTCCTCTGGT AGCCATGGAG CTGGTGCGGG CCAGGTTGGA AAGAGGTAGC 
AACAAGAGTC AGGAAAGGGA GCTGGCCACT CCTGACTGGA CAGAGCGCCA GCTAGCCCAT 
GGCGGTCTGG CCGAGGTACT TCGGGTTGTC GGCGACTCCA GGAGATCACG AGAGACACAG 
GTGGTCGCTG TGCTGGGCAA GGCTGGTCAG GGCAAGAGCC ACTGGGCCAG GACAGTGAGC 
CACATTTGGG CACAAGGCCA GTTACCACAA TATGACTTTG TCTTCTACGT CCCCTGTCAA 
TGCTTGGATC GCCCTGGGGA CACCTACCAC CTGCGGGATC TGCTCTGTCC CCCGAACCTG 
CAGCCACTGG CCATGGATGA CGAGGTCATT GATCATATTG TGAGGCAGCC GGACCGTGTT 
CTGCTCATCC TAGATGCTTT TGAGGAGCTA GAGGCCCAAG ACAGCCTCCT GCATGGACCC 
TGTGGACCTC TGTCCCCAGA GCCCTGCTCC CTCCGGGGAC TGCTGGCTGG GCTCTTCCAG 
CGTAAGCTGC TGCGAGGCTG CACCCTGCTC CTCACAGCCC GGCCCCGGGG CCGCCTGGCT 
CAGAGCCTGA GCAAGGCAGA TGCCATCTTC GAGGTGCCCA GCTTCTCTAC GAAACAGGCC 
CAGATCTATA TGAGGCACTA CTTTGAGAAC TCAGGGACAG CAGGGAGTCA CGACAAGGCC 
CTGGGCCTCC TGGAGGGCCA GCCTTTTCTC CTCACCCACA GTCACAGCCC TGTTCTGTGC 
AGTGCCGTGT GTCAGCTCTC CAAGGCCCTG CTGGATCAGG GCGCAGAGGC CCAGCTACCT 
TGCACACTCA CAGGACTCTA TGTTGGCCTG CTAGGCCCTG CAGCTCAGAA CAGTCCTCCT 
GGAGCCTTAG TTGAGTTGGC CAAGCTAGCC TGGGAGCTGG GACGGAGGCA CCAAAGCACC 
TTGCAGGAAA CCCAGTTTCC ATCCGTGGAA GTGAAGACCT GGGCTGTGGC CCAAGGCTTG 
ATGCAGCAGA CCACAGAGGC CCAACTGGCT TTCTCCAGTT TTCTGCTACA GTGCTTCCTG 
GGTGCTGTGT GGCTGGCACA GTGCAATGAG ATGAAAGACA AGGAGCTGCC ACAGTACCTG 
GCCTTGACCC CGAGGAAGAA GCGACCCTAT GACAACTGGC TGGAGGGCGT ACCACGCTTT 
CTGGCTGGCT TAGTTTTCCA GCCTCGAGCC CACTGCCTGG GAGCTCTGGT GGAGCCTGCA 
ATGGCTGCAG TGGCAGATAG GAAACGGAAG GTTCTTACCA GGTACCTGAA GCGCTTGAAG 
CTGGGGACAC TTCGGGCCGG GAGGTTGCTG GAGCTGCTAC ACTGTGCCCA CGAAACACAG 
GAACCTGGTA TTTGGAAGCA TGTTTCACAC CAGCTCCCAG GGCACCTCTC CTTCCTGGGC 
ACACGGCTCA CAGCCCCAGA TGTGTATGTT CTGGGCAGGG CCTTGGAGAC AGCCAGCCAG 
GACTTCTCCT TGGACCTTCG TCAGACTGGC ATCGAGCCCT CCAGACTGGG AGACCTCGTG 
GGACTCAGCT GTGTCACCAG TTTCAGGGCC TCCTTGAGTG ACACAATGGC ATTATGGGAG 
TCCCTACAGC ATCAGGGAGA AACCCAGCTA CTCCAGGCGG CAGAGGAGAA GTTCACCATT 
GAGCCATTTA AGGCCAAATC CCCAAAGGAT GTGGAAGACC TGGACAGCCT TGTGCAGACC 
CAGAGGCTGA GAAACCCCTC AGCGGATGCA GCCAAGGATC TTCCTGCCAT CCGGGACCTT 
AAGAAGCTAG AGTTTGCATT GGGCCCCGTC TTGGGCCCGC AGGCTTTCCC CACACTGGCC 
AAGATCCTTC CAGCATTCTC TTCCCTGCAG CACCTGGACC TGGACTCACT TAGCGAGAAC 
AAGATCGGGG ACAAGGGTGT GTCGAAGCTC TCAGCCACCT TCCCTCAGCT GAAGGCCCTG 
GAGACGCTCA ACCTGTCCCA GAATAGCATC ACCGATGTGG GAGCTTGCAA GCTTGCAGAA 
GCCCTGCCGG CCCTGGCCAA GTCCCTCCTA AGGCTGAGCT TGTACAACAA CTGCATCTGT 
GACGAAGGGG CCAAGAGCCT GGCACGAGTG CTTCCAGACA TGGTGTCCCT CCGGGTGATG 
GATGTCCAGT TCAACAAGTT CACGGCTGTC GGGGCCCAGC AGCTGACCTC CAGCCTTCAG 
AAGTGCCCTC AGGTGGAGAC ACTGGCAATG TGGACACCCA CTATCCCCTT TGGGGTCCAG 
GAACACCTGC AGCAGCTGGA TGCCCGGATT AGCCTGAGAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ciita ( NM_001270804.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001257733.1 Rattus norvegicus class II, major histocompatibility complex, transactivator (Ciita), transcript variant 3, mRNA.

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CloneID	ORa09836
Clone ID Related Accession (Same CDS sequence)	XM_008767501.2 , NM_001270804.1
Accession Version	NM_001270804.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3159bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-20
Organism	Rattus norvegicus(Norway rat)
Product	MHC class II transactivator isoform 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC103514.7. Transcript Variant: This variant (3) has an alternate first exon compared to variant 1. The resulting isoform (3) is shorter at the N-terminus compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF251307.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGCTGG GGTCTCCAGA GGGCAGCTAC CTGGAGCTCC TTAACAGTGA TGCTGACCCC 
CTACACCTCT ACCACCTCTA TGACCAGATG GACCTTGCTG GGGAGGAAGA GATCGAACTC 
AACTCAGAGA CAGACATGGA CACCATCAAC TGTGACCAGT TCAGCAAGCT GTTGCAGGAT 
ATGGAAATGG ATGAAGAGAC CCGGGAGGCC TATGCCAATA TCGCGGAACT GGATCAGTAC 
GTGTTCCAGG ATACCCAGCT GGAGGGCCTG AGCAAGGACC TCTTCATACA GCACATTGGA 
CCAGAGGAAG GCTTTGGTGA GAACGTAGAG GGCCCTGCAG AATCAGGAGA GAAGCCTCAG 
AAGAGACGCT TCCCAGAAGA GCATGCTATG GACTCAAAGC ACAGGAAACT AGTGCCTCCC 
TCTAGGACCT CACTGAACTA TTTGGATCTC CCCGCTGGGC ATATCCAGAT CTTCACCACT 
CTGCCCCAGG GACTCTGGCA AATCTCAGGG GTTGGCACAG GGCTCTCCAG TGTCCTAGTC 
TACCACGGTG AGATGCCCCA GGTCAACCAA TTACTCTCTT CAAGCAGCCC CACTGTCCCC 
AGTCTCCCCG AGTCCCCAGA CCGGCCTGGC TCCACCAGCC CCTTCGCGCC ATCCACAGCT 
GACCTGCCCG GCATGCCTGA ACCTGCTCTG ACCTCCCGTG TAAATGAGAC AGAGGACACA 
ACACCCCCCT CCCCATGCCA AGAGGATCCC GAGCCTTCCA TCAAGCTTCC AAAATGGCCA 
GAGTCCGTGG AGCGGTTCCA GCACTCCCTA CAGGACAAGT ACCAAGCACT GCCCGGGAGC 
CCAAGTGGTC CTCTGGTAGC CATGGAGCTG GTGCGGGCCA GGTTGGAAAG AGGTAGCAAC 
AAGAGTCAGG AAAGGGAGCT GGCCACTCCT GACTGGACAG AGCGCCAGCT AGCCCATGGC 
GGTCTGGCCG AGGTACTTCG GGTTGTCGGC GACTCCAGGA GATCACGAGA GACACAGGTG 
GTCGCTGTGC TGGGCAAGGC TGGTCAGGGC AAGAGCCACT GGGCCAGGAC AGTGAGCCAC 
ATTTGGGCAC AAGGCCAGTT ACCACAATAT GACTTTGTCT TCTACGTCCC CTGTCAATGC 
TTGGATCGCC CTGGGGACAC CTACCACCTG CGGGATCTGC TCTGTCCCCC GAACCTGCAG 
CCACTGGCCA TGGATGACGA GGTCATTGAT CATATTGTGA GGCAGCCGGA CCGTGTTCTG 
CTCATCCTAG ATGCTTTTGA GGAGCTAGAG GCCCAAGACA GCCTCCTGCA TGGACCCTGT 
GGACCTCTGT CCCCAGAGCC CTGCTCCCTC CGGGGACTGC TGGCTGGGCT CTTCCAGCGT 
AAGCTGCTGC GAGGCTGCAC CCTGCTCCTC ACAGCCCGGC CCCGGGGCCG CCTGGCTCAG 
AGCCTGAGCA AGGCAGATGC CATCTTCGAG GTGCCCAGCT TCTCTACGAA ACAGGCCCAG 
ATCTATATGA GGCACTACTT TGAGAACTCA GGGACAGCAG GGAGTCACGA CAAGGCCCTG 
GGCCTCCTGG AGGGCCAGCC TTTTCTCCTC ACCCACAGTC ACAGCCCTGT TCTGTGCAGT 
GCCGTGTGTC AGCTCTCCAA GGCCCTGCTG GATCAGGGCG CAGAGGCCCA GCTACCTTGC 
ACACTCACAG GACTCTATGT TGGCCTGCTA GGCCCTGCAG CTCAGAACAG TCCTCCTGGA 
GCCTTAGTTG AGTTGGCCAA GCTAGCCTGG GAGCTGGGAC GGAGGCACCA AAGCACCTTG 
CAGGAAACCC AGTTTCCATC CGTGGAAGTG AAGACCTGGG CTGTGGCCCA AGGCTTGATG 
CAGCAGACCA CAGAGGCCCA ACTGGCTTTC TCCAGTTTTC TGCTACAGTG CTTCCTGGGT 
GCTGTGTGGC TGGCACAGTG CAATGAGATG AAAGACAAGG AGCTGCCACA GTACCTGGCC 
TTGACCCCGA GGAAGAAGCG ACCCTATGAC AACTGGCTGG AGGGCGTACC ACGCTTTCTG 
GCTGGCTTAG TTTTCCAGCC TCGAGCCCAC TGCCTGGGAG CTCTGGTGGA GCCTGCAATG 
GCTGCAGTGG CAGATAGGAA ACGGAAGGTT CTTACCAGGT ACCTGAAGCG CTTGAAGCTG 
GGGACACTTC GGGCCGGGAG GTTGCTGGAG CTGCTACACT GTGCCCACGA AACACAGGAA 
CCTGGTATTT GGAAGCATGT TTCACACCAG CTCCCAGGGC ACCTCTCCTT CCTGGGCACA 
CGGCTCACAG CCCCAGATGT GTATGTTCTG GGCAGGGCCT TGGAGACAGC CAGCCAGGAC 
TTCTCCTTGG ACCTTCGTCA GACTGGCATC GAGCCCTCCA GACTGGGAGA CCTCGTGGGA 
CTCAGCTGTG TCACCAGTTT CAGGGCCTCC TTGAGTGACA CAATGGCATT ATGGGAGTCC 
CTACAGCATC AGGGAGAAAC CCAGCTACTC CAGGCGGCAG AGGAGAAGTT CACCATTGAG 
CCATTTAAGG CCAAATCCCC AAAGGATGTG GAAGACCTGG ACAGCCTTGT GCAGACCCAG 
AGGCTGAGAA ACCCCTCAGC GGATGCAGCC AAGGATCTTC CTGCCATCCG GGACCTTAAG 
AAGCTAGAGT TTGCATTGGG CCCCGTCTTG GGCCCGCAGG CTTTCCCCAC ACTGGCCAAG 
ATCCTTCCAG CATTCTCTTC CCTGCAGCAC CTGGACCTGG ACTCACTTAG CGAGAACAAG 
ATCGGGGACA AGGGTGTGTC GAAGCTCTCA GCCACCTTCC CTCAGCTGAA GGCCCTGGAG 
ACGCTCAACC TGTCCCAGAA TAGCATCACC GATGTGGGAG CTTGCAAGCT TGCAGAAGCC 
CTGCCGGCCC TGGCCAAGTC CCTCCTAAGG CTGAGCTTGT ACAACAACTG CATCTGTGAC 
GAAGGGGCCA AGAGCCTGGC ACGAGTGCTT CCAGACATGG TGTCCCTCCG GGTGATGGAT 
GTCCAGTTCA ACAAGTTCAC GGCTGTCGGG GCCCAGCAGC TGACCTCCAG CCTTCAGAAG 
TGCCCTCAGG TGGAGACACT GGCAATGTGG ACACCCACTA TCCCCTTTGG GGTCCAGGAA 
CACCTGCAGC AGCTGGATGC CCGGATTAGC CTGAGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001257733.1
CDS	95..3253
Translation	MELGSPEGSYLELLNSDADPLHLYHLYDQMDLAGEEEIELNSETDMDTINCDQFSKLLQDMEMDEETREAYANIAELDQYVFQDTQLEGLSKDLFIQHIGPEEGFGENVEGPAESGEKPQKRRFPEEHAMDSKHRKLVPPSRTSLNYLDLPAGHIQIFTTLPQGLWQISGVGTGLSSVLVYHGEMPQVNQLLSSSSPTVPSLPESPDRPGSTSPFAPSTADLPGMPEPALTSRVNETEDTTPPSPCQEDPEPSIKLPKWPESVERFQHSLQDKYQALPGSPSGPLVAMELVRARLERGSNKSQERELATPDWTERQLAHGGLAEVLRVVGDSRRSRETQVVAVLGKAGQGKSHWARTVSHIWAQGQLPQYDFVFYVPCQCLDRPGDTYHLRDLLCPPNLQPLAMDDEVIDHIVRQPDRVLLILDAFEELEAQDSLLHGPCGPLSPEPCSLRGLLAGLFQRKLLRGCTLLLTARPRGRLAQSLSKADAIFEVPSFSTKQAQIYMRHYFENSGTAGSHDKALGLLEGQPFLLTHSHSPVLCSAVCQLSKALLDQGAEAQLPCTLTGLYVGLLGPAAQNSPPGALVELAKLAWELGRRHQSTLQETQFPSVEVKTWAVAQGLMQQTTEAQLAFSSFLLQCFLGAVWLAQCNEMKDKELPQYLALTPRKKRPYDNWLEGVPRFLAGLVFQPRAHCLGALVEPAMAAVADRKRKVLTRYLKRLKLGTLRAGRLLELLHCAHETQEPGIWKHVSHQLPGHLSFLGTRLTAPDVYVLGRALETASQDFSLDLRQTGIEPSRLGDLVGLSCVTSFRASLSDTMALWESLQHQGETQLLQAAEEKFTIEPFKAKSPKDVEDLDSLVQTQRLRNPSADAAKDLPAIRDLKKLEFALGPVLGPQAFPTLAKILPAFSSLQHLDLDSLSENKIGDKGVSKLSATFPQLKALETLNLSQNSITDVGACKLAEALPALAKSLLRLSLYNNCICDEGAKSLARVLPDMVSLRVMDVQFNKFTAVGAQQLTSSLQKCPQVETLAMWTPTIPFGVQEHLQQLDARISLR

Target ORF information:

RefSeq Version	NM_001270804.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus class II, major histocompatibility complex, transactivator (Ciita), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001270804.1

ORF Insert Sequence:

ATGGAGCTGG GGTCTCCAGA GGGCAGCTAC CTGGAGCTCC TTAACAGTGA TGCTGACCCC 
CTACACCTCT ACCACCTCTA TGACCAGATG GACCTTGCTG GGGAGGAAGA GATCGAACTC 
AACTCAGAGA CAGACATGGA CACCATCAAC TGTGACCAGT TCAGCAAGCT GTTGCAGGAT 
ATGGAAATGG ATGAAGAGAC CCGGGAGGCC TATGCCAATA TCGCGGAACT GGATCAGTAC 
GTGTTCCAGG ATACCCAGCT GGAGGGCCTG AGCAAGGACC TCTTCATACA GCACATTGGA 
CCAGAGGAAG GCTTTGGTGA GAACGTAGAG GGCCCTGCAG AATCAGGAGA GAAGCCTCAG 
AAGAGACGCT TCCCAGAAGA GCATGCTATG GACTCAAAGC ACAGGAAACT AGTGCCTCCC 
TCTAGGACCT CACTGAACTA TTTGGATCTC CCCGCTGGGC ATATCCAGAT CTTCACCACT 
CTGCCCCAGG GACTCTGGCA AATCTCAGGG GTTGGCACAG GGCTCTCCAG TGTCCTAGTC 
TACCACGGTG AGATGCCCCA GGTCAACCAA TTACTCTCTT CAAGCAGCCC CACTGTCCCC 
AGTCTCCCCG AGTCCCCAGA CCGGCCTGGC TCCACCAGCC CCTTCGCGCC ATCCACAGCT 
GACCTGCCCG GCATGCCTGA ACCTGCTCTG ACCTCCCGTG TAAATGAGAC AGAGGACACA 
ACACCCCCCT CCCCATGCCA AGAGGATCCC GAGCCTTCCA TCAAGCTTCC AAAATGGCCA 
GAGTCCGTGG AGCGGTTCCA GCACTCCCTA CAGGACAAGT ACCAAGCACT GCCCGGGAGC 
CCAAGTGGTC CTCTGGTAGC CATGGAGCTG GTGCGGGCCA GGTTGGAAAG AGGTAGCAAC 
AAGAGTCAGG AAAGGGAGCT GGCCACTCCT GACTGGACAG AGCGCCAGCT AGCCCATGGC 
GGTCTGGCCG AGGTACTTCG GGTTGTCGGC GACTCCAGGA GATCACGAGA GACACAGGTG 
GTCGCTGTGC TGGGCAAGGC TGGTCAGGGC AAGAGCCACT GGGCCAGGAC AGTGAGCCAC 
ATTTGGGCAC AAGGCCAGTT ACCACAATAT GACTTTGTCT TCTACGTCCC CTGTCAATGC 
TTGGATCGCC CTGGGGACAC CTACCACCTG CGGGATCTGC TCTGTCCCCC GAACCTGCAG 
CCACTGGCCA TGGATGACGA GGTCATTGAT CATATTGTGA GGCAGCCGGA CCGTGTTCTG 
CTCATCCTAG ATGCTTTTGA GGAGCTAGAG GCCCAAGACA GCCTCCTGCA TGGACCCTGT 
GGACCTCTGT CCCCAGAGCC CTGCTCCCTC CGGGGACTGC TGGCTGGGCT CTTCCAGCGT 
AAGCTGCTGC GAGGCTGCAC CCTGCTCCTC ACAGCCCGGC CCCGGGGCCG CCTGGCTCAG 
AGCCTGAGCA AGGCAGATGC CATCTTCGAG GTGCCCAGCT TCTCTACGAA ACAGGCCCAG 
ATCTATATGA GGCACTACTT TGAGAACTCA GGGACAGCAG GGAGTCACGA CAAGGCCCTG 
GGCCTCCTGG AGGGCCAGCC TTTTCTCCTC ACCCACAGTC ACAGCCCTGT TCTGTGCAGT 
GCCGTGTGTC AGCTCTCCAA GGCCCTGCTG GATCAGGGCG CAGAGGCCCA GCTACCTTGC 
ACACTCACAG GACTCTATGT TGGCCTGCTA GGCCCTGCAG CTCAGAACAG TCCTCCTGGA 
GCCTTAGTTG AGTTGGCCAA GCTAGCCTGG GAGCTGGGAC GGAGGCACCA AAGCACCTTG 
CAGGAAACCC AGTTTCCATC CGTGGAAGTG AAGACCTGGG CTGTGGCCCA AGGCTTGATG 
CAGCAGACCA CAGAGGCCCA ACTGGCTTTC TCCAGTTTTC TGCTACAGTG CTTCCTGGGT 
GCTGTGTGGC TGGCACAGTG CAATGAGATG AAAGACAAGG AGCTGCCACA GTACCTGGCC 
TTGACCCCGA GGAAGAAGCG ACCCTATGAC AACTGGCTGG AGGGCGTACC ACGCTTTCTG 
GCTGGCTTAG TTTTCCAGCC TCGAGCCCAC TGCCTGGGAG CTCTGGTGGA GCCTGCAATG 
GCTGCAGTGG CAGATAGGAA ACGGAAGGTT CTTACCAGGT ACCTGAAGCG CTTGAAGCTG 
GGGACACTTC GGGCCGGGAG GTTGCTGGAG CTGCTACACT GTGCCCACGA AACACAGGAA 
CCTGGTATTT GGAAGCATGT TTCACACCAG CTCCCAGGGC ACCTCTCCTT CCTGGGCACA 
CGGCTCACAG CCCCAGATGT GTATGTTCTG GGCAGGGCCT TGGAGACAGC CAGCCAGGAC 
TTCTCCTTGG ACCTTCGTCA GACTGGCATC GAGCCCTCCA GACTGGGAGA CCTCGTGGGA 
CTCAGCTGTG TCACCAGTTT CAGGGCCTCC TTGAGTGACA CAATGGCATT ATGGGAGTCC 
CTACAGCATC AGGGAGAAAC CCAGCTACTC CAGGCGGCAG AGGAGAAGTT CACCATTGAG 
CCATTTAAGG CCAAATCCCC AAAGGATGTG GAAGACCTGG ACAGCCTTGT GCAGACCCAG 
AGGCTGAGAA ACCCCTCAGC GGATGCAGCC AAGGATCTTC CTGCCATCCG GGACCTTAAG 
AAGCTAGAGT TTGCATTGGG CCCCGTCTTG GGCCCGCAGG CTTTCCCCAC ACTGGCCAAG 
ATCCTTCCAG CATTCTCTTC CCTGCAGCAC CTGGACCTGG ACTCACTTAG CGAGAACAAG 
ATCGGGGACA AGGGTGTGTC GAAGCTCTCA GCCACCTTCC CTCAGCTGAA GGCCCTGGAG 
ACGCTCAACC TGTCCCAGAA TAGCATCACC GATGTGGGAG CTTGCAAGCT TGCAGAAGCC 
CTGCCGGCCC TGGCCAAGTC CCTCCTAAGG CTGAGCTTGT ACAACAACTG CATCTGTGAC 
GAAGGGGCCA AGAGCCTGGC ACGAGTGCTT CCAGACATGG TGTCCCTCCG GGTGATGGAT 
GTCCAGTTCA ACAAGTTCAC GGCTGTCGGG GCCCAGCAGC TGACCTCCAG CCTTCAGAAG 
TGCCCTCAGG TGGAGACACT GGCAATGTGG ACACCCACTA TCCCCTTTGG GGTCCAGGAA 
CACCTGCAGC AGCTGGATGC CCGGATTAGC CTGAGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ciita ( XM_006245738.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006245800.1 Rattus norvegicus class II, major histocompatibility complex, transactivator (Ciita), transcript variant X1, mRNA.

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CloneID	ORa09812
Clone ID Related Accession (Same CDS sequence)	NM_053529.2 , XM_006245738.3
Accession Version	XM_006245738.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3462bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	MHC class II transactivator isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005109.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006245738.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAACCACT TCCAGGCCAT CCTGGCCCAG GTGCAGACAC TGCTGTCCAG TCAGCAGCCC 
AGGCAGGTGC GGGCCCTCCT GGATGGCTTG CTGGAAGAAG AGCTGCTCTC ACGGGAATAC 
CATTGTGCCC TGCTTCATGA GCCTGATGGT GAGGCTCTGG CCCGGAAGAT TTCCCTCACC 
TTGCTGGAGA AAGGGGACCT GGACTTGGCG TTTGTGAGCT GGGTTTGCAA CAGGCTGCAG 
GTCCCTGAGG TAGAGAGGGG CCCCAACTGC AGGGACCATG GAGGCCATAC TCTGTGTGCC 
ACCATGGAGC TGGGGTCTCC AGAGGGCAGC TACCTGGAGC TCCTTAACAG TGATGCTGAC 
CCCCTACACC TCTACCACCT CTATGACCAG ATGGACCTTG CTGGGGAGGA AGAGATCGAA 
CTCAACTCAG AGACAGACAT GGACACCATC AACTGTGACC AGTTCAGCAA GCTGTTGCAG 
GATATGGAAA TGGATGAAGA GACCCGGGAG GCCTATGCCA ATATCGCGGA ACTGGATCAG 
TACGTGTTCC AGGATACCCA GCTGGAGGGC CTGAGCAAGG ACCTCTTCAT ACAGCACATT 
GGACCAGAGG AAGGCTTTGG TGAGAACGTA GAGGGCCCTG CAGAATCAGG AGAGAAGCCT 
CAGAAGAGAC GCTTCCCAGA AGAGCATGCT ATGGACTCAA AGCACAGGAA ACTAGTGCCT 
CCCTCTAGGA CCTCACTGAA CTATTTGGAT CTCCCCGCTG GGCATATCCA GATCTTCACC 
ACTCTGCCCC AGGGACTCTG GCAAATCTCA GGGGTTGGCA CAGGGCTCTC CAGTGTCCTA 
GTCTACCACG GTGAGATGCC CCAGGTCAAC CAATTACTCT CTTCAAGCAG CCCCACTGTC 
CCCAGTCTCC CCGAGTCCCC AGACCGGCCT GGCTCCACCA GCCCCTTCGC GCCATCCACA 
GCTGACCTGC CCGGCATGCC TGAACCTGCT CTGACCTCCC GTGTAAATGA GACAGAGGAC 
ACAACACCCC CCTCCCCATG CCAAGAGGAT CCCGAGCCTT CCATCAAGCT TCCAAAATGG 
CCAGAGTCCG TGGAGCGGTT CCAGCACTCC CTACAGGACA AGTACCAAGC ACTGCCCGGG 
AGCCCAAGTG GTCCTCTGGT AGCCATGGAG CTGGTGCGGG CCAGGTTGGA AAGAGGTAGC 
AACAAGAGTC AGGAAAGGGA GCTGGCCACT CCTGACTGGA CAGAGCGCCA GCTAGCCCAT 
GGCGGTCTGG CCGAGGTACT TCGGGTTGTC GGCGACTCCA GGAGATCACG AGAGACACAG 
GTGGTCGCTG TGCTGGGCAA GGCTGGTCAG GGCAAGAGCC ACTGGGCCAG GACAGTGAGC 
CACATTTGGG CACAAGGCCA GTTACCACAA TATGACTTTG TCTTCTACGT CCCCTGTCAA 
TGCTTGGATC GCCCTGGGGA CACCTACCAC CTGCGGGATC TGCTCTGTCC CCCGAACCTG 
CAGCCACTGG CCATGGATGA CGAGGTCATT GATCATATTG TGAGGCAGCC GGACCGTGTT 
CTGCTCATCC TAGATGCTTT TGAGGAGCTA GAGGCCCAAG ACAGCCTCCT GCATGGACCC 
TGTGGACCTC TGTCCCCAGA GCCCTGCTCC CTCCGGGGAC TGCTGGCTGG GCTCTTCCAG 
CGTAAGCTGC TGCGAGGCTG CACCCTGCTC CTCACAGCCC GGCCCCGGGG CCGCCTGGCT 
CAGAGCCTGA GCAAGGCAGA TGCCATCTTC GAGGTGCCCA GCTTCTCTAC GAAACAGGCC 
CAGATCTATA TGAGGCACTA CTTTGAGAAC TCAGGGACAG CAGGGAGTCA CGACAAGGCC 
CTGGGCCTCC TGGAGGGCCA GCCTTTTCTC CTCACCCACA GTCACAGCCC TGTTCTGTGC 
AGTGCCGTGT GTCAGCTCTC CAAGGCCCTG CTGGATCAGG GCGCAGAGGC CCAGCTACCT 
TGCACACTCA CAGGACTCTA TGTTGGCCTG CTAGGCCCTG CAGCTCAGAA CAGTCCTCCT 
GGAGCCTTAG TTGAGTTGGC CAAGCTAGCC TGGGAGCTGG GACGGAGGCA CCAAAGCACC 
TTGCAGGAAA CCCAGTTTCC ATCCGTGGAA GTGAAGACCT GGGCTGTGGC CCAAGGCTTG 
ATGCAGCAGA CCACAGAGGC CCAACTGGCT TTCTCCAGTT TTCTGCTACA GTGCTTCCTG 
GGTGCTGTGT GGCTGGCACA GTGCAATGAG ATGAAAGACA AGGAGCTGCC ACAGTACCTG 
GCCTTGACCC CGAGGAAGAA GCGACCCTAT GACAACTGGC TGGAGGGCGT ACCACGCTTT 
CTGGCTGGCT TAGTTTTCCA GCCTCGAGCC CACTGCCTGG GAGCTCTGGT GGAGCCTGCA 
ATGGCTGCAG TGGCAGATAG GAAACGGAAG GTTCTTACCA GGTACCTGAA GCGCTTGAAG 
CTGGGGACAC TTCGGGCCGG GAGGTTGCTG GAGCTGCTAC ACTGTGCCCA CGAAACACAG 
GAACCTGGTA TTTGGAAGCA TGTTTCACAC CAGCTCCCAG GGCACCTCTC CTTCCTGGGC 
ACACGGCTCA CAGCCCCAGA TGTGTATGTT CTGGGCAGGG CCTTGGAGAC AGCCAGCCAG 
GACTTCTCCT TGGACCTTCG TCAGACTGGC ATCGAGCCCT CCAGACTGGG AGACCTCGTG 
GGACTCAGCT GTGTCACCAG TTTCAGGGCC TCCTTGAGTG ACACAATGGC ATTATGGGAG 
TCCCTACAGC ATCAGGGAGA AACCCAGCTA CTCCAGGCGG CAGAGGAGAA GTTCACCATT 
GAGCCATTTA AGGCCAAATC CCCAAAGGAT GTGGAAGACC TGGACAGCCT TGTGCAGACC 
CAGAGGCTGA GAAACCCCTC AGCGGATGCA GCCAAGGATC TTCCTGCCAT CCGGGACCTT 
AAGAAGCTAG AGTTTGCATT GGGCCCCGTC TTGGGCCCGC AGGCTTTCCC CACACTGGCC 
AAGATCCTTC CAGCATTCTC TTCCCTGCAG CACCTGGACC TGGACTCACT TAGCGAGAAC 
AAGATCGGGG ACAAGGGTGT GTCGAAGCTC TCAGCCACCT TCCCTCAGCT GAAGGCCCTG 
GAGACGCTCA ACCTGTCCCA GAATAGCATC ACCGATGTGG GAGCTTGCAA GCTTGCAGAA 
GCCCTGCCGG CCCTGGCCAA GTCCCTCCTA AGGCTGAGCT TGTACAACAA CTGCATCTGT 
GACGAAGGGG CCAAGAGCCT GGCACGAGTG CTTCCAGACA TGGTGTCCCT CCGGGTGATG 
GATGTCCAGT TCAACAAGTT CACGGCTGTC GGGGCCCAGC AGCTGACCTC CAGCCTTCAG 
AAGTGCCCTC AGGTGGAGAC ACTGGCAATG TGGACACCCA CTATCCCCTT TGGGGTCCAG 
GAACACCTGC AGCAGCTGGA TGCCCGGATT AGCCTGAGAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006245800.1
CDS	116..3577
Translation	MNHFQAILAQVQTLLSSQQPRQVRALLDGLLEEELLSREYHCALLHEPDGEALARKISLTLLEKGDLDLAFVSWVCNRLQVPEVERGPNCRDHGGHTLCATMELGSPEGSYLELLNSDADPLHLYHLYDQMDLAGEEEIELNSETDMDTINCDQFSKLLQDMEMDEETREAYANIAELDQYVFQDTQLEGLSKDLFIQHIGPEEGFGENVEGPAESGEKPQKRRFPEEHAMDSKHRKLVPPSRTSLNYLDLPAGHIQIFTTLPQGLWQISGVGTGLSSVLVYHGEMPQVNQLLSSSSPTVPSLPESPDRPGSTSPFAPSTADLPGMPEPALTSRVNETEDTTPPSPCQEDPEPSIKLPKWPESVERFQHSLQDKYQALPGSPSGPLVAMELVRARLERGSNKSQERELATPDWTERQLAHGGLAEVLRVVGDSRRSRETQVVAVLGKAGQGKSHWARTVSHIWAQGQLPQYDFVFYVPCQCLDRPGDTYHLRDLLCPPNLQPLAMDDEVIDHIVRQPDRVLLILDAFEELEAQDSLLHGPCGPLSPEPCSLRGLLAGLFQRKLLRGCTLLLTARPRGRLAQSLSKADAIFEVPSFSTKQAQIYMRHYFENSGTAGSHDKALGLLEGQPFLLTHSHSPVLCSAVCQLSKALLDQGAEAQLPCTLTGLYVGLLGPAAQNSPPGALVELAKLAWELGRRHQSTLQETQFPSVEVKTWAVAQGLMQQTTEAQLAFSSFLLQCFLGAVWLAQCNEMKDKELPQYLALTPRKKRPYDNWLEGVPRFLAGLVFQPRAHCLGALVEPAMAAVADRKRKVLTRYLKRLKLGTLRAGRLLELLHCAHETQEPGIWKHVSHQLPGHLSFLGTRLTAPDVYVLGRALETASQDFSLDLRQTGIEPSRLGDLVGLSCVTSFRASLSDTMALWESLQHQGETQLLQAAEEKFTIEPFKAKSPKDVEDLDSLVQTQRLRNPSADAAKDLPAIRDLKKLEFALGPVLGPQAFPTLAKILPAFSSLQHLDLDSLSENKIGDKGVSKLSATFPQLKALETLNLSQNSITDVGACKLAEALPALAKSLLRLSLYNNCICDEGAKSLARVLPDMVSLRVMDVQFNKFTAVGAQQLTSSLQKCPQVETLAMWTPTIPFGVQEHLQQLDARISLR

Target ORF information:

RefSeq Version	XM_006245738.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus class II, major histocompatibility complex, transactivator (Ciita), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006245738.3

ORF Insert Sequence:

ATGAACCACT TCCAGGCCAT CCTGGCCCAG GTGCAGACAC TGCTGTCCAG TCAGCAGCCC 
AGGCAGGTGC GGGCCCTCCT GGATGGCTTG CTGGAAGAAG AGCTGCTCTC ACGGGAATAC 
CATTGTGCCC TGCTTCATGA GCCTGATGGT GAGGCTCTGG CCCGGAAGAT TTCCCTCACC 
TTGCTGGAGA AAGGGGACCT GGACTTGGCG TTTGTGAGCT GGGTTTGCAA CAGGCTGCAG 
GTCCCTGAGG TAGAGAGGGG CCCCAACTGC AGGGACCATG GAGGCCATAC TCTGTGTGCC 
ACCATGGAGC TGGGGTCTCC AGAGGGCAGC TACCTGGAGC TCCTTAACAG TGATGCTGAC 
CCCCTACACC TCTACCACCT CTATGACCAG ATGGACCTTG CTGGGGAGGA AGAGATCGAA 
CTCAACTCAG AGACAGACAT GGACACCATC AACTGTGACC AGTTCAGCAA GCTGTTGCAG 
GATATGGAAA TGGATGAAGA GACCCGGGAG GCCTATGCCA ATATCGCGGA ACTGGATCAG 
TACGTGTTCC AGGATACCCA GCTGGAGGGC CTGAGCAAGG ACCTCTTCAT ACAGCACATT 
GGACCAGAGG AAGGCTTTGG TGAGAACGTA GAGGGCCCTG CAGAATCAGG AGAGAAGCCT 
CAGAAGAGAC GCTTCCCAGA AGAGCATGCT ATGGACTCAA AGCACAGGAA ACTAGTGCCT 
CCCTCTAGGA CCTCACTGAA CTATTTGGAT CTCCCCGCTG GGCATATCCA GATCTTCACC 
ACTCTGCCCC AGGGACTCTG GCAAATCTCA GGGGTTGGCA CAGGGCTCTC CAGTGTCCTA 
GTCTACCACG GTGAGATGCC CCAGGTCAAC CAATTACTCT CTTCAAGCAG CCCCACTGTC 
CCCAGTCTCC CCGAGTCCCC AGACCGGCCT GGCTCCACCA GCCCCTTCGC GCCATCCACA 
GCTGACCTGC CCGGCATGCC TGAACCTGCT CTGACCTCCC GTGTAAATGA GACAGAGGAC 
ACAACACCCC CCTCCCCATG CCAAGAGGAT CCCGAGCCTT CCATCAAGCT TCCAAAATGG 
CCAGAGTCCG TGGAGCGGTT CCAGCACTCC CTACAGGACA AGTACCAAGC ACTGCCCGGG 
AGCCCAAGTG GTCCTCTGGT AGCCATGGAG CTGGTGCGGG CCAGGTTGGA AAGAGGTAGC 
AACAAGAGTC AGGAAAGGGA GCTGGCCACT CCTGACTGGA CAGAGCGCCA GCTAGCCCAT 
GGCGGTCTGG CCGAGGTACT TCGGGTTGTC GGCGACTCCA GGAGATCACG AGAGACACAG 
GTGGTCGCTG TGCTGGGCAA GGCTGGTCAG GGCAAGAGCC ACTGGGCCAG GACAGTGAGC 
CACATTTGGG CACAAGGCCA GTTACCACAA TATGACTTTG TCTTCTACGT CCCCTGTCAA 
TGCTTGGATC GCCCTGGGGA CACCTACCAC CTGCGGGATC TGCTCTGTCC CCCGAACCTG 
CAGCCACTGG CCATGGATGA CGAGGTCATT GATCATATTG TGAGGCAGCC GGACCGTGTT 
CTGCTCATCC TAGATGCTTT TGAGGAGCTA GAGGCCCAAG ACAGCCTCCT GCATGGACCC 
TGTGGACCTC TGTCCCCAGA GCCCTGCTCC CTCCGGGGAC TGCTGGCTGG GCTCTTCCAG 
CGTAAGCTGC TGCGAGGCTG CACCCTGCTC CTCACAGCCC GGCCCCGGGG CCGCCTGGCT 
CAGAGCCTGA GCAAGGCAGA TGCCATCTTC GAGGTGCCCA GCTTCTCTAC GAAACAGGCC 
CAGATCTATA TGAGGCACTA CTTTGAGAAC TCAGGGACAG CAGGGAGTCA CGACAAGGCC 
CTGGGCCTCC TGGAGGGCCA GCCTTTTCTC CTCACCCACA GTCACAGCCC TGTTCTGTGC 
AGTGCCGTGT GTCAGCTCTC CAAGGCCCTG CTGGATCAGG GCGCAGAGGC CCAGCTACCT 
TGCACACTCA CAGGACTCTA TGTTGGCCTG CTAGGCCCTG CAGCTCAGAA CAGTCCTCCT 
GGAGCCTTAG TTGAGTTGGC CAAGCTAGCC TGGGAGCTGG GACGGAGGCA CCAAAGCACC 
TTGCAGGAAA CCCAGTTTCC ATCCGTGGAA GTGAAGACCT GGGCTGTGGC CCAAGGCTTG 
ATGCAGCAGA CCACAGAGGC CCAACTGGCT TTCTCCAGTT TTCTGCTACA GTGCTTCCTG 
GGTGCTGTGT GGCTGGCACA GTGCAATGAG ATGAAAGACA AGGAGCTGCC ACAGTACCTG 
GCCTTGACCC CGAGGAAGAA GCGACCCTAT GACAACTGGC TGGAGGGCGT ACCACGCTTT 
CTGGCTGGCT TAGTTTTCCA GCCTCGAGCC CACTGCCTGG GAGCTCTGGT GGAGCCTGCA 
ATGGCTGCAG TGGCAGATAG GAAACGGAAG GTTCTTACCA GGTACCTGAA GCGCTTGAAG 
CTGGGGACAC TTCGGGCCGG GAGGTTGCTG GAGCTGCTAC ACTGTGCCCA CGAAACACAG 
GAACCTGGTA TTTGGAAGCA TGTTTCACAC CAGCTCCCAG GGCACCTCTC CTTCCTGGGC 
ACACGGCTCA CAGCCCCAGA TGTGTATGTT CTGGGCAGGG CCTTGGAGAC AGCCAGCCAG 
GACTTCTCCT TGGACCTTCG TCAGACTGGC ATCGAGCCCT CCAGACTGGG AGACCTCGTG 
GGACTCAGCT GTGTCACCAG TTTCAGGGCC TCCTTGAGTG ACACAATGGC ATTATGGGAG 
TCCCTACAGC ATCAGGGAGA AACCCAGCTA CTCCAGGCGG CAGAGGAGAA GTTCACCATT 
GAGCCATTTA AGGCCAAATC CCCAAAGGAT GTGGAAGACC TGGACAGCCT TGTGCAGACC 
CAGAGGCTGA GAAACCCCTC AGCGGATGCA GCCAAGGATC TTCCTGCCAT CCGGGACCTT 
AAGAAGCTAG AGTTTGCATT GGGCCCCGTC TTGGGCCCGC AGGCTTTCCC CACACTGGCC 
AAGATCCTTC CAGCATTCTC TTCCCTGCAG CACCTGGACC TGGACTCACT TAGCGAGAAC 
AAGATCGGGG ACAAGGGTGT GTCGAAGCTC TCAGCCACCT TCCCTCAGCT GAAGGCCCTG 
GAGACGCTCA ACCTGTCCCA GAATAGCATC ACCGATGTGG GAGCTTGCAA GCTTGCAGAA 
GCCCTGCCGG CCCTGGCCAA GTCCCTCCTA AGGCTGAGCT TGTACAACAA CTGCATCTGT 
GACGAAGGGG CCAAGAGCCT GGCACGAGTG CTTCCAGACA TGGTGTCCCT CCGGGTGATG 
GATGTCCAGT TCAACAAGTT CACGGCTGTC GGGGCCCAGC AGCTGACCTC CAGCCTTCAG 
AAGTGCCCTC AGGTGGAGAC ACTGGCAATG TGGACACCCA CTATCCCCTT TGGGGTCCAG 
GAACACCTGC AGCAGCTGGA TGCCCGGATT AGCCTGAGAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ciita ( XM_008767501.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008765723.1 Rattus norvegicus class II, major histocompatibility complex, transactivator (Ciita), transcript variant X2, mRNA.

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CloneID	ORa09836
Clone ID Related Accession (Same CDS sequence)	XM_008767501.2 , NM_001270804.1
Accession Version	XM_008767501.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3159bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	MHC class II transactivator isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005109.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008767501.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGCTGG GGTCTCCAGA GGGCAGCTAC CTGGAGCTCC TTAACAGTGA TGCTGACCCC 
CTACACCTCT ACCACCTCTA TGACCAGATG GACCTTGCTG GGGAGGAAGA GATCGAACTC 
AACTCAGAGA CAGACATGGA CACCATCAAC TGTGACCAGT TCAGCAAGCT GTTGCAGGAT 
ATGGAAATGG ATGAAGAGAC CCGGGAGGCC TATGCCAATA TCGCGGAACT GGATCAGTAC 
GTGTTCCAGG ATACCCAGCT GGAGGGCCTG AGCAAGGACC TCTTCATACA GCACATTGGA 
CCAGAGGAAG GCTTTGGTGA GAACGTAGAG GGCCCTGCAG AATCAGGAGA GAAGCCTCAG 
AAGAGACGCT TCCCAGAAGA GCATGCTATG GACTCAAAGC ACAGGAAACT AGTGCCTCCC 
TCTAGGACCT CACTGAACTA TTTGGATCTC CCCGCTGGGC ATATCCAGAT CTTCACCACT 
CTGCCCCAGG GACTCTGGCA AATCTCAGGG GTTGGCACAG GGCTCTCCAG TGTCCTAGTC 
TACCACGGTG AGATGCCCCA GGTCAACCAA TTACTCTCTT CAAGCAGCCC CACTGTCCCC 
AGTCTCCCCG AGTCCCCAGA CCGGCCTGGC TCCACCAGCC CCTTCGCGCC ATCCACAGCT 
GACCTGCCCG GCATGCCTGA ACCTGCTCTG ACCTCCCGTG TAAATGAGAC AGAGGACACA 
ACACCCCCCT CCCCATGCCA AGAGGATCCC GAGCCTTCCA TCAAGCTTCC AAAATGGCCA 
GAGTCCGTGG AGCGGTTCCA GCACTCCCTA CAGGACAAGT ACCAAGCACT GCCCGGGAGC 
CCAAGTGGTC CTCTGGTAGC CATGGAGCTG GTGCGGGCCA GGTTGGAAAG AGGTAGCAAC 
AAGAGTCAGG AAAGGGAGCT GGCCACTCCT GACTGGACAG AGCGCCAGCT AGCCCATGGC 
GGTCTGGCCG AGGTACTTCG GGTTGTCGGC GACTCCAGGA GATCACGAGA GACACAGGTG 
GTCGCTGTGC TGGGCAAGGC TGGTCAGGGC AAGAGCCACT GGGCCAGGAC AGTGAGCCAC 
ATTTGGGCAC AAGGCCAGTT ACCACAATAT GACTTTGTCT TCTACGTCCC CTGTCAATGC 
TTGGATCGCC CTGGGGACAC CTACCACCTG CGGGATCTGC TCTGTCCCCC GAACCTGCAG 
CCACTGGCCA TGGATGACGA GGTCATTGAT CATATTGTGA GGCAGCCGGA CCGTGTTCTG 
CTCATCCTAG ATGCTTTTGA GGAGCTAGAG GCCCAAGACA GCCTCCTGCA TGGACCCTGT 
GGACCTCTGT CCCCAGAGCC CTGCTCCCTC CGGGGACTGC TGGCTGGGCT CTTCCAGCGT 
AAGCTGCTGC GAGGCTGCAC CCTGCTCCTC ACAGCCCGGC CCCGGGGCCG CCTGGCTCAG 
AGCCTGAGCA AGGCAGATGC CATCTTCGAG GTGCCCAGCT TCTCTACGAA ACAGGCCCAG 
ATCTATATGA GGCACTACTT TGAGAACTCA GGGACAGCAG GGAGTCACGA CAAGGCCCTG 
GGCCTCCTGG AGGGCCAGCC TTTTCTCCTC ACCCACAGTC ACAGCCCTGT TCTGTGCAGT 
GCCGTGTGTC AGCTCTCCAA GGCCCTGCTG GATCAGGGCG CAGAGGCCCA GCTACCTTGC 
ACACTCACAG GACTCTATGT TGGCCTGCTA GGCCCTGCAG CTCAGAACAG TCCTCCTGGA 
GCCTTAGTTG AGTTGGCCAA GCTAGCCTGG GAGCTGGGAC GGAGGCACCA AAGCACCTTG 
CAGGAAACCC AGTTTCCATC CGTGGAAGTG AAGACCTGGG CTGTGGCCCA AGGCTTGATG 
CAGCAGACCA CAGAGGCCCA ACTGGCTTTC TCCAGTTTTC TGCTACAGTG CTTCCTGGGT 
GCTGTGTGGC TGGCACAGTG CAATGAGATG AAAGACAAGG AGCTGCCACA GTACCTGGCC 
TTGACCCCGA GGAAGAAGCG ACCCTATGAC AACTGGCTGG AGGGCGTACC ACGCTTTCTG 
GCTGGCTTAG TTTTCCAGCC TCGAGCCCAC TGCCTGGGAG CTCTGGTGGA GCCTGCAATG 
GCTGCAGTGG CAGATAGGAA ACGGAAGGTT CTTACCAGGT ACCTGAAGCG CTTGAAGCTG 
GGGACACTTC GGGCCGGGAG GTTGCTGGAG CTGCTACACT GTGCCCACGA AACACAGGAA 
CCTGGTATTT GGAAGCATGT TTCACACCAG CTCCCAGGGC ACCTCTCCTT CCTGGGCACA 
CGGCTCACAG CCCCAGATGT GTATGTTCTG GGCAGGGCCT TGGAGACAGC CAGCCAGGAC 
TTCTCCTTGG ACCTTCGTCA GACTGGCATC GAGCCCTCCA GACTGGGAGA CCTCGTGGGA 
CTCAGCTGTG TCACCAGTTT CAGGGCCTCC TTGAGTGACA CAATGGCATT ATGGGAGTCC 
CTACAGCATC AGGGAGAAAC CCAGCTACTC CAGGCGGCAG AGGAGAAGTT CACCATTGAG 
CCATTTAAGG CCAAATCCCC AAAGGATGTG GAAGACCTGG ACAGCCTTGT GCAGACCCAG 
AGGCTGAGAA ACCCCTCAGC GGATGCAGCC AAGGATCTTC CTGCCATCCG GGACCTTAAG 
AAGCTAGAGT TTGCATTGGG CCCCGTCTTG GGCCCGCAGG CTTTCCCCAC ACTGGCCAAG 
ATCCTTCCAG CATTCTCTTC CCTGCAGCAC CTGGACCTGG ACTCACTTAG CGAGAACAAG 
ATCGGGGACA AGGGTGTGTC GAAGCTCTCA GCCACCTTCC CTCAGCTGAA GGCCCTGGAG 
ACGCTCAACC TGTCCCAGAA TAGCATCACC GATGTGGGAG CTTGCAAGCT TGCAGAAGCC 
CTGCCGGCCC TGGCCAAGTC CCTCCTAAGG CTGAGCTTGT ACAACAACTG CATCTGTGAC 
GAAGGGGCCA AGAGCCTGGC ACGAGTGCTT CCAGACATGG TGTCCCTCCG GGTGATGGAT 
GTCCAGTTCA ACAAGTTCAC GGCTGTCGGG GCCCAGCAGC TGACCTCCAG CCTTCAGAAG 
TGCCCTCAGG TGGAGACACT GGCAATGTGG ACACCCACTA TCCCCTTTGG GGTCCAGGAA 
CACCTGCAGC AGCTGGATGC CCGGATTAGC CTGAGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008765723.1
CDS	1420..4578
Translation	MELGSPEGSYLELLNSDADPLHLYHLYDQMDLAGEEEIELNSETDMDTINCDQFSKLLQDMEMDEETREAYANIAELDQYVFQDTQLEGLSKDLFIQHIGPEEGFGENVEGPAESGEKPQKRRFPEEHAMDSKHRKLVPPSRTSLNYLDLPAGHIQIFTTLPQGLWQISGVGTGLSSVLVYHGEMPQVNQLLSSSSPTVPSLPESPDRPGSTSPFAPSTADLPGMPEPALTSRVNETEDTTPPSPCQEDPEPSIKLPKWPESVERFQHSLQDKYQALPGSPSGPLVAMELVRARLERGSNKSQERELATPDWTERQLAHGGLAEVLRVVGDSRRSRETQVVAVLGKAGQGKSHWARTVSHIWAQGQLPQYDFVFYVPCQCLDRPGDTYHLRDLLCPPNLQPLAMDDEVIDHIVRQPDRVLLILDAFEELEAQDSLLHGPCGPLSPEPCSLRGLLAGLFQRKLLRGCTLLLTARPRGRLAQSLSKADAIFEVPSFSTKQAQIYMRHYFENSGTAGSHDKALGLLEGQPFLLTHSHSPVLCSAVCQLSKALLDQGAEAQLPCTLTGLYVGLLGPAAQNSPPGALVELAKLAWELGRRHQSTLQETQFPSVEVKTWAVAQGLMQQTTEAQLAFSSFLLQCFLGAVWLAQCNEMKDKELPQYLALTPRKKRPYDNWLEGVPRFLAGLVFQPRAHCLGALVEPAMAAVADRKRKVLTRYLKRLKLGTLRAGRLLELLHCAHETQEPGIWKHVSHQLPGHLSFLGTRLTAPDVYVLGRALETASQDFSLDLRQTGIEPSRLGDLVGLSCVTSFRASLSDTMALWESLQHQGETQLLQAAEEKFTIEPFKAKSPKDVEDLDSLVQTQRLRNPSADAAKDLPAIRDLKKLEFALGPVLGPQAFPTLAKILPAFSSLQHLDLDSLSENKIGDKGVSKLSATFPQLKALETLNLSQNSITDVGACKLAEALPALAKSLLRLSLYNNCICDEGAKSLARVLPDMVSLRVMDVQFNKFTAVGAQQLTSSLQKCPQVETLAMWTPTIPFGVQEHLQQLDARISLR

Target ORF information:

RefSeq Version	XM_008767501.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus class II, major histocompatibility complex, transactivator (Ciita), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008767501.2

ORF Insert Sequence:

ATGGAGCTGG GGTCTCCAGA GGGCAGCTAC CTGGAGCTCC TTAACAGTGA TGCTGACCCC 
CTACACCTCT ACCACCTCTA TGACCAGATG GACCTTGCTG GGGAGGAAGA GATCGAACTC 
AACTCAGAGA CAGACATGGA CACCATCAAC TGTGACCAGT TCAGCAAGCT GTTGCAGGAT 
ATGGAAATGG ATGAAGAGAC CCGGGAGGCC TATGCCAATA TCGCGGAACT GGATCAGTAC 
GTGTTCCAGG ATACCCAGCT GGAGGGCCTG AGCAAGGACC TCTTCATACA GCACATTGGA 
CCAGAGGAAG GCTTTGGTGA GAACGTAGAG GGCCCTGCAG AATCAGGAGA GAAGCCTCAG 
AAGAGACGCT TCCCAGAAGA GCATGCTATG GACTCAAAGC ACAGGAAACT AGTGCCTCCC 
TCTAGGACCT CACTGAACTA TTTGGATCTC CCCGCTGGGC ATATCCAGAT CTTCACCACT 
CTGCCCCAGG GACTCTGGCA AATCTCAGGG GTTGGCACAG GGCTCTCCAG TGTCCTAGTC 
TACCACGGTG AGATGCCCCA GGTCAACCAA TTACTCTCTT CAAGCAGCCC CACTGTCCCC 
AGTCTCCCCG AGTCCCCAGA CCGGCCTGGC TCCACCAGCC CCTTCGCGCC ATCCACAGCT 
GACCTGCCCG GCATGCCTGA ACCTGCTCTG ACCTCCCGTG TAAATGAGAC AGAGGACACA 
ACACCCCCCT CCCCATGCCA AGAGGATCCC GAGCCTTCCA TCAAGCTTCC AAAATGGCCA 
GAGTCCGTGG AGCGGTTCCA GCACTCCCTA CAGGACAAGT ACCAAGCACT GCCCGGGAGC 
CCAAGTGGTC CTCTGGTAGC CATGGAGCTG GTGCGGGCCA GGTTGGAAAG AGGTAGCAAC 
AAGAGTCAGG AAAGGGAGCT GGCCACTCCT GACTGGACAG AGCGCCAGCT AGCCCATGGC 
GGTCTGGCCG AGGTACTTCG GGTTGTCGGC GACTCCAGGA GATCACGAGA GACACAGGTG 
GTCGCTGTGC TGGGCAAGGC TGGTCAGGGC AAGAGCCACT GGGCCAGGAC AGTGAGCCAC 
ATTTGGGCAC AAGGCCAGTT ACCACAATAT GACTTTGTCT TCTACGTCCC CTGTCAATGC 
TTGGATCGCC CTGGGGACAC CTACCACCTG CGGGATCTGC TCTGTCCCCC GAACCTGCAG 
CCACTGGCCA TGGATGACGA GGTCATTGAT CATATTGTGA GGCAGCCGGA CCGTGTTCTG 
CTCATCCTAG ATGCTTTTGA GGAGCTAGAG GCCCAAGACA GCCTCCTGCA TGGACCCTGT 
GGACCTCTGT CCCCAGAGCC CTGCTCCCTC CGGGGACTGC TGGCTGGGCT CTTCCAGCGT 
AAGCTGCTGC GAGGCTGCAC CCTGCTCCTC ACAGCCCGGC CCCGGGGCCG CCTGGCTCAG 
AGCCTGAGCA AGGCAGATGC CATCTTCGAG GTGCCCAGCT TCTCTACGAA ACAGGCCCAG 
ATCTATATGA GGCACTACTT TGAGAACTCA GGGACAGCAG GGAGTCACGA CAAGGCCCTG 
GGCCTCCTGG AGGGCCAGCC TTTTCTCCTC ACCCACAGTC ACAGCCCTGT TCTGTGCAGT 
GCCGTGTGTC AGCTCTCCAA GGCCCTGCTG GATCAGGGCG CAGAGGCCCA GCTACCTTGC 
ACACTCACAG GACTCTATGT TGGCCTGCTA GGCCCTGCAG CTCAGAACAG TCCTCCTGGA 
GCCTTAGTTG AGTTGGCCAA GCTAGCCTGG GAGCTGGGAC GGAGGCACCA AAGCACCTTG 
CAGGAAACCC AGTTTCCATC CGTGGAAGTG AAGACCTGGG CTGTGGCCCA AGGCTTGATG 
CAGCAGACCA CAGAGGCCCA ACTGGCTTTC TCCAGTTTTC TGCTACAGTG CTTCCTGGGT 
GCTGTGTGGC TGGCACAGTG CAATGAGATG AAAGACAAGG AGCTGCCACA GTACCTGGCC 
TTGACCCCGA GGAAGAAGCG ACCCTATGAC AACTGGCTGG AGGGCGTACC ACGCTTTCTG 
GCTGGCTTAG TTTTCCAGCC TCGAGCCCAC TGCCTGGGAG CTCTGGTGGA GCCTGCAATG 
GCTGCAGTGG CAGATAGGAA ACGGAAGGTT CTTACCAGGT ACCTGAAGCG CTTGAAGCTG 
GGGACACTTC GGGCCGGGAG GTTGCTGGAG CTGCTACACT GTGCCCACGA AACACAGGAA 
CCTGGTATTT GGAAGCATGT TTCACACCAG CTCCCAGGGC ACCTCTCCTT CCTGGGCACA 
CGGCTCACAG CCCCAGATGT GTATGTTCTG GGCAGGGCCT TGGAGACAGC CAGCCAGGAC 
TTCTCCTTGG ACCTTCGTCA GACTGGCATC GAGCCCTCCA GACTGGGAGA CCTCGTGGGA 
CTCAGCTGTG TCACCAGTTT CAGGGCCTCC TTGAGTGACA CAATGGCATT ATGGGAGTCC 
CTACAGCATC AGGGAGAAAC CCAGCTACTC CAGGCGGCAG AGGAGAAGTT CACCATTGAG 
CCATTTAAGG CCAAATCCCC AAAGGATGTG GAAGACCTGG ACAGCCTTGT GCAGACCCAG 
AGGCTGAGAA ACCCCTCAGC GGATGCAGCC AAGGATCTTC CTGCCATCCG GGACCTTAAG 
AAGCTAGAGT TTGCATTGGG CCCCGTCTTG GGCCCGCAGG CTTTCCCCAC ACTGGCCAAG 
ATCCTTCCAG CATTCTCTTC CCTGCAGCAC CTGGACCTGG ACTCACTTAG CGAGAACAAG 
ATCGGGGACA AGGGTGTGTC GAAGCTCTCA GCCACCTTCC CTCAGCTGAA GGCCCTGGAG 
ACGCTCAACC TGTCCCAGAA TAGCATCACC GATGTGGGAG CTTGCAAGCT TGCAGAAGCC 
CTGCCGGCCC TGGCCAAGTC CCTCCTAAGG CTGAGCTTGT ACAACAACTG CATCTGTGAC 
GAAGGGGCCA AGAGCCTGGC ACGAGTGCTT CCAGACATGG TGTCCCTCCG GGTGATGGAT 
GTCCAGTTCA ACAAGTTCAC GGCTGTCGGG GCCCAGCAGC TGACCTCCAG CCTTCAGAAG 
TGCCCTCAGG TGGAGACACT GGCAATGTGG ACACCCACTA TCCCCTTTGG GGTCCAGGAA 
CACCTGCAGC AGCTGGATGC CCGGATTAGC CTGAGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Allelic difference in Mhc2ta confers altered microglial activation and susceptibility to ?-synuclein-induced dopaminergic neurodegeneration.
Neurobiology of disease106279-290(2017 Oct)
Jimenez-Ferrer I,Jewett M,Tontanahal A,Romero-Ramos M,Swanberg M

Downregulating immunogenicity of Schwann cells via inhibiting a potential target of class II transactivator (CIITA) gene.
Bioscience trends7(1)50-5(2013 Feb)
Yang Y,Dai W,Chen Z,Yan Z,Yao Z,Zhang C

PML promotes MHC class II gene expression by stabilizing the class II transactivator.
The Journal of cell biology199(1)49-63(2012 Oct)
Ulbricht T,Alzrigat M,Horch A,Reuter N,von Mikecz A,Steimle V,Schmitt E,Kr?mer OH,Stamminger T,Hemmerich P

Interrogating the complex role of chromosome 16p13.13 in multiple sclerosis susceptibility: independent genetic signals in the CIITA-CLEC16A-SOCS1 gene complex.
Human molecular genetics20(17)3517-24(2011 Sep)
Zuvich RL,Bush WS,McCauley JL,Beecham AH,De Jager PL,,Ivinson AJ,Compston A,Hafler DA,Hauser SL,Sawcer SJ,Pericak-Vance MA,Barcellos LF,Mortlock DP,Haines JL

NLR family member NLRC5 is a transcriptional regulator of MHC class I genes.
Proceedings of the National Academy of Sciences of the United States of America107(31)13794-9(2010 Aug)
Meissner TB,Li A,Biswas A,Lee KH,Liu YJ,Bayir E,Iliopoulos D,van den Elsen PJ,Kobayashi KS

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Ciita cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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