Entpd6 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Entpd6
Entrez Gene ID	85260
Full Name	ectonucleoside triphosphate diphosphohydrolase 6
General protein information	Preferred Names ectonucleoside triphosphate diphosphohydrolase 6 Names ectonucleoside triphosphate diphosphohydrolase 6 CD39 antigen-like 2 NTPDase 6
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 3 Map Location: 3q41
Summary	nucleoside diphosphatase; may mediate glycosylation reactions in the Golgi apparatus; may catalyze hydrolysis of extracellular nucleotides [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_006235218.3	XP_006235280.1	ectonucleoside triphosphate diphosphohydrolase 6 isoform X1
NM_053498.1	NP_445950.1	ectonucleoside triphosphate diphosphohydrolase 6

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Entpd6	NP_742115.2
Oryza sativa (rice)	Os12g0123500	NP_001066032.1
Oryza sativa (rice)	Os11g0440200	NP_001067814.2
Homo sapiens (human)	ENTPD6	NP_001238.2
Pan troglodytes (chimpanzee)	ENTPD6	XP_003316901.1
Canis lupus familiaris (dog)	ENTPD6	XP_542683.3
Rattus norvegicus (Norway rat)	Entpd6	NP_445950.1
	ENTPD6	XP_001099703.2
Oryza sativa (rice)	Os11g0439600	NP_001067813.1
Oryza sativa (rice)	Os11g0126800	NP_001065626.1
Xenopus tropicalis (tropical clawed frog)	entpd6	XP_004914735.1
Bos taurus (cattle)	ENTPD6	NP_001039456.1
Oryza sativa (rice)	Os11g0125900	NP_001065622.2
Oryza sativa (rice)	Os11g0126400	NP_001065624.1
Danio rerio (zebrafish)	entpd6	NP_001017862.1
Eremothecium gossypii	AGOS_AFR362C	NP_985909.1

Gene Ontology
Bibliography

Related articles in PubMed

Hair cell specific NTPDase6 immunolocalisation in vestibular end organs: potential role of purinergic signaling in vestibular sensory transduction.
O'Keeffe MG, Thorne PR, Housley GD, Robson SC, Vlajkovic SM
Journal of vestibular research : equilibrium & orientation22(5-6)213-9(2012)

Bacterial expression, characterization, and disulfide bond determination of soluble human NTPDase6 (CD39L2) nucleotidase: implications for structure and function.
Ivanenkov VV, Murphy-Piedmonte DM, Kirley TL
Biochemistry42(40)11726-35(2003 Oct)

Expression and characterization of soluble and membrane-bound human nucleoside triphosphate diphosphohydrolase 6 (CD39L2).
Hicks-Berger CA, Chadwick BP, Frischauf AM, Kirley TL
The Journal of biological chemistry275(44)34041-5(2000 Nov)

Sequencing, functional expression and characterization of rat NTPDase6, a nucleoside diphosphatase and novel member of the ecto-nucleoside triphosphate diphosphohydrolase family.
Braun N, Fengler S, Ebeling C, Servos J, Zimmermann H
The Biochemical journal351 Pt 3639-47(2000 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

NTPDase6 immunolocalisation in the vestibular end organ could be linked to the regulation of P2 receptor signalling and sensory transduction, including maintenance of vestibular hair bundles.
Title: Hair cell specific NTPDase6 immunolocalisation in vestibular end organs: potential role of purinergic signaling in vestibular sensory transduction.

The following Entpd6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Entpd6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa09729	NM_053498.1 Latest version!	Rattus norvegicus ectonucleoside triphosphate diphosphohydrolase 6 (Entpd6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
ORa09729	XM_006235218.3 Latest version!	Rattus norvegicus ectonucleoside triphosphate diphosphohydrolase 6 (Entpd6), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Entpd6 ( NM_053498.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_445950.1 Rattus norvegicus ectonucleoside triphosphate diphosphohydrolase 6 (Entpd6), mRNA.

Price & Availability↑

CloneID	ORa09729
Clone ID Related Accession (Same CDS sequence)	XM_006235218.3 , NM_053498.1
Accession Version	NM_053498.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1368bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-15
Organism	Rattus norvegicus(Norway rat)
Product	ectonucleoside triphosphate diphosphohydrolase 6
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AJ277748.1. ##Evidence-Data-START## Transcript exon combination :: AJ277748.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGAGAAAAA TACCAAACCA TGGGACCTTG CGGATGACGA AGGTGGCGTA TCCCCTGGGA 
CTGTGCGTGG GCCTGTTCAT CTATGTTGCC TATATCAAGT GGCACCGGGC CTCCGCCGCC 
CAGGCCTTCT TCACCATTGC TGGGGCTGCC TCAGGAGTGC GGTGGACCCA ACAGGCCTTC 
AGCTCTCCAG ACTCAGCCAC ACGTGGTCAC GAGGTCTTCT ATGGGATCAT GTTTGATGCC 
GGGAGTACCG GCACCCGCAT CCACGTCTTC CAGTTTGCCC GGCCACCTGG AGAAACTCCC 
ACCTTGACCC ACGAAACCTT CAAAGCTCTG AAGCCTGGGC TTTCTGCGTA TGCCGATGAT 
GTTGAAAAGA GCGCCCAAGG GATCCAGGAG CTTCTGAATG TCGCCAAGCA ACACATTCCA 
TACGACTTCT GGAAGGCCAC CCCTCTGGTT CTCAAGGCCA CAGCTGGTCT GCGCCTGCTG 
CCGGGAGAAA AGGCTCAGAA GTTGCTGCAA AAGGTGAAGG AGGTGTTTAA GGCATCACCC 
TTCCTTGTAG GGGATGACTG TGTTTCCATC ATGAATGGCA CAGATGAAGG TGTTTCGGCT 
TGGATCACTG TCAACTTCCT GACAGGCAGT CTGAAGACCC CAGGAAGCAG CAGTGTGGGC 
ATGCTGGACT TGGGCGGAGG ATCCACTCAG ATCACCTTCC TCCCACGTGT CGAGGGTACC 
CTGCAGGCCT CCCCACCCGG CCACCTGACA GCGCTGCAGA TGTTTAACAG GACTTTCAAG 
CTGTATTCCT ACAGCTACCT GGGGCTGGGA CTGATGTCGG CACGACTGGC TATCTTGGGT 
GGTGTGGAGG GGAAACCTGC TGAGGATGAC AAGGAACTGG TCAGCCCCTG TCTGTCTCCC 
CGGTTCAGAG GAAAGTGGGA GCATGCGGAG GTCACCTATA GAATTTCAGG ACAGAAGGCA 
GTGGGCCTCT ACGAGCTGTG TGCCAGCAGG GTATCAGAAG TCCTCCGCAA TAAAGTACAC 
AGGACAGAAG AGGCGCAGCA CGTGGACTTC TATGCGTTTT CCTACTACTA CGACCTTGCT 
GCCAGCTTTG GCCTTATAGA TGCAGAGAAA GGAGGCAGCC TTGTAGTTGG AGACTTTGAG 
ATAGCAGCCA AGTATGTCTG CCGCACTCTG GAGACACAGC CTCCAAGCAG CCCCTTTGCT 
TGCATGGACC TCACCTACAT CAGCCTCCTG CTCCACGAGT TTGGTTTTCC CGGGGACAAG 
GTACTGAAGC TGGCTCGGAA AATTGACAAT GTTGAAACCA GCTGGGCTCT GGGGGCTATT 
TTTCATTACA TCGACTCCCT GAAGAGACAG AAGGTTCCTG CCTTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_445950.1
CDS	129..1496
Translation	MRKIPNHGTLRMTKVAYPLGLCVGLFIYVAYIKWHRASAAQAFFTIAGAASGVRWTQQAFSSPDSATRGHEVFYGIMFDAGSTGTRIHVFQFARPPGETPTLTHETFKALKPGLSAYADDVEKSAQGIQELLNVAKQHIPYDFWKATPLVLKATAGLRLLPGEKAQKLLQKVKEVFKASPFLVGDDCVSIMNGTDEGVSAWITVNFLTGSLKTPGSSSVGMLDLGGGSTQITFLPRVEGTLQASPPGHLTALQMFNRTFKLYSYSYLGLGLMSARLAILGGVEGKPAEDDKELVSPCLSPRFRGKWEHAEVTYRISGQKAVGLYELCASRVSEVLRNKVHRTEEAQHVDFYAFSYYYDLAASFGLIDAEKGGSLVVGDFEIAAKYVCRTLETQPPSSPFACMDLTYISLLLHEFGFPGDKVLKLARKIDNVETSWALGAIFHYIDSLKRQKVPAL

Target ORF information:

RefSeq Version	NM_053498.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus ectonucleoside triphosphate diphosphohydrolase 6 (Entpd6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_053498.1

ORF Insert Sequence:

ATGAGAAAAA TACCAAACCA TGGGACCTTG CGGATGACGA AGGTGGCGTA TCCCCTGGGA 
CTGTGCGTGG GCCTGTTCAT CTATGTTGCC TATATCAAGT GGCACCGGGC CTCCGCCGCC 
CAGGCCTTCT TCACCATTGC TGGGGCTGCC TCAGGAGTGC GGTGGACCCA ACAGGCCTTC 
AGCTCTCCAG ACTCAGCCAC ACGTGGTCAC GAGGTCTTCT ATGGGATCAT GTTTGATGCC 
GGGAGTACCG GCACCCGCAT CCACGTCTTC CAGTTTGCCC GGCCACCTGG AGAAACTCCC 
ACCTTGACCC ACGAAACCTT CAAAGCTCTG AAGCCTGGGC TTTCTGCGTA TGCCGATGAT 
GTTGAAAAGA GCGCCCAAGG GATCCAGGAG CTTCTGAATG TCGCCAAGCA ACACATTCCA 
TACGACTTCT GGAAGGCCAC CCCTCTGGTT CTCAAGGCCA CAGCTGGTCT GCGCCTGCTG 
CCGGGAGAAA AGGCTCAGAA GTTGCTGCAA AAGGTGAAGG AGGTGTTTAA GGCATCACCC 
TTCCTTGTAG GGGATGACTG TGTTTCCATC ATGAATGGCA CAGATGAAGG TGTTTCGGCT 
TGGATCACTG TCAACTTCCT GACAGGCAGT CTGAAGACCC CAGGAAGCAG CAGTGTGGGC 
ATGCTGGACT TGGGCGGAGG ATCCACTCAG ATCACCTTCC TCCCACGTGT CGAGGGTACC 
CTGCAGGCCT CCCCACCCGG CCACCTGACA GCGCTGCAGA TGTTTAACAG GACTTTCAAG 
CTGTATTCCT ACAGCTACCT GGGGCTGGGA CTGATGTCGG CACGACTGGC TATCTTGGGT 
GGTGTGGAGG GGAAACCTGC TGAGGATGAC AAGGAACTGG TCAGCCCCTG TCTGTCTCCC 
CGGTTCAGAG GAAAGTGGGA GCATGCGGAG GTCACCTATA GAATTTCAGG ACAGAAGGCA 
GTGGGCCTCT ACGAGCTGTG TGCCAGCAGG GTATCAGAAG TCCTCCGCAA TAAAGTACAC 
AGGACAGAAG AGGCGCAGCA CGTGGACTTC TATGCGTTTT CCTACTACTA CGACCTTGCT 
GCCAGCTTTG GCCTTATAGA TGCAGAGAAA GGAGGCAGCC TTGTAGTTGG AGACTTTGAG 
ATAGCAGCCA AGTATGTCTG CCGCACTCTG GAGACACAGC CTCCAAGCAG CCCCTTTGCT 
TGCATGGACC TCACCTACAT CAGCCTCCTG CTCCACGAGT TTGGTTTTCC CGGGGACAAG 
GTACTGAAGC TGGCTCGGAA AATTGACAAT GTTGAAACCA GCTGGGCTCT GGGGGCTATT 
TTTCATTACA TCGACTCCCT GAAGAGACAG AAGGTTCCTG CCTTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Entpd6 ( XM_006235218.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006235280.1 Rattus norvegicus ectonucleoside triphosphate diphosphohydrolase 6 (Entpd6), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa09729
Clone ID Related Accession (Same CDS sequence)	XM_006235218.3 , NM_053498.1
Accession Version	XM_006235218.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1368bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	ectonucleoside triphosphate diphosphohydrolase 6 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006235218.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGAAAAA TACCAAACCA TGGGACCTTG CGGATGACGA AGGTGGCGTA TCCCCTGGGA 
CTGTGCGTGG GCCTGTTCAT CTATGTTGCC TATATCAAGT GGCACCGGGC CTCCGCCGCC 
CAGGCCTTCT TCACCATTGC TGGGGCTGCC TCAGGAGTGC GGTGGACCCA ACAGGCCTTC 
AGCTCTCCAG ACTCAGCCAC ACGTGGTCAC GAGGTCTTCT ATGGGATCAT GTTTGATGCC 
GGGAGTACCG GCACCCGCAT CCACGTCTTC CAGTTTGCCC GGCCACCTGG AGAAACTCCC 
ACCTTGACCC ACGAAACCTT CAAAGCTCTG AAGCCTGGGC TTTCTGCGTA TGCCGATGAT 
GTTGAAAAGA GCGCCCAAGG GATCCAGGAG CTTCTGAATG TCGCCAAGCA ACACATTCCA 
TACGACTTCT GGAAGGCCAC CCCTCTGGTT CTCAAGGCCA CAGCTGGTCT GCGCCTGCTG 
CCGGGAGAAA AGGCTCAGAA GTTGCTGCAA AAGGTGAAGG AGGTGTTTAA GGCATCACCC 
TTCCTTGTAG GGGATGACTG TGTTTCCATC ATGAATGGCA CAGATGAAGG TGTTTCGGCT 
TGGATCACTG TCAACTTCCT GACAGGCAGT CTGAAGACCC CAGGAAGCAG CAGTGTGGGC 
ATGCTGGACT TGGGCGGAGG ATCCACTCAG ATCACCTTCC TCCCACGTGT CGAGGGTACC 
CTGCAGGCCT CCCCACCCGG CCACCTGACA GCGCTGCAGA TGTTTAACAG GACTTTCAAG 
CTGTATTCCT ACAGCTACCT GGGGCTGGGA CTGATGTCGG CACGACTGGC TATCTTGGGT 
GGTGTGGAGG GGAAACCTGC TGAGGATGAC AAGGAACTGG TCAGCCCCTG TCTGTCTCCC 
CGGTTCAGAG GAAAGTGGGA GCATGCGGAG GTCACCTATA GAATTTCAGG ACAGAAGGCA 
GTGGGCCTCT ACGAGCTGTG TGCCAGCAGG GTATCAGAAG TCCTCCGCAA TAAAGTACAC 
AGGACAGAAG AGGCGCAGCA CGTGGACTTC TATGCGTTTT CCTACTACTA CGACCTTGCT 
GCCAGCTTTG GCCTTATAGA TGCAGAGAAA GGAGGCAGCC TTGTAGTTGG AGACTTTGAG 
ATAGCAGCCA AGTATGTCTG CCGCACTCTG GAGACACAGC CTCCAAGCAG CCCCTTTGCT 
TGCATGGACC TCACCTACAT CAGCCTCCTG CTCCACGAGT TTGGTTTTCC CGGGGACAAG 
GTACTGAAGC TGGCTCGGAA AATTGACAAT GTTGAAACCA GCTGGGCTCT GGGGGCTATT 
TTTCATTACA TCGACTCCCT GAAGAGACAG AAGGTTCCTG CCTTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006235280.1
CDS	194..1561
Translation	MRKIPNHGTLRMTKVAYPLGLCVGLFIYVAYIKWHRASAAQAFFTIAGAASGVRWTQQAFSSPDSATRGHEVFYGIMFDAGSTGTRIHVFQFARPPGETPTLTHETFKALKPGLSAYADDVEKSAQGIQELLNVAKQHIPYDFWKATPLVLKATAGLRLLPGEKAQKLLQKVKEVFKASPFLVGDDCVSIMNGTDEGVSAWITVNFLTGSLKTPGSSSVGMLDLGGGSTQITFLPRVEGTLQASPPGHLTALQMFNRTFKLYSYSYLGLGLMSARLAILGGVEGKPAEDDKELVSPCLSPRFRGKWEHAEVTYRISGQKAVGLYELCASRVSEVLRNKVHRTEEAQHVDFYAFSYYYDLAASFGLIDAEKGGSLVVGDFEIAAKYVCRTLETQPPSSPFACMDLTYISLLLHEFGFPGDKVLKLARKIDNVETSWALGAIFHYIDSLKRQKVPAL

Target ORF information:

RefSeq Version	XM_006235218.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus ectonucleoside triphosphate diphosphohydrolase 6 (Entpd6), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006235218.3

ORF Insert Sequence:

ATGAGAAAAA TACCAAACCA TGGGACCTTG CGGATGACGA AGGTGGCGTA TCCCCTGGGA 
CTGTGCGTGG GCCTGTTCAT CTATGTTGCC TATATCAAGT GGCACCGGGC CTCCGCCGCC 
CAGGCCTTCT TCACCATTGC TGGGGCTGCC TCAGGAGTGC GGTGGACCCA ACAGGCCTTC 
AGCTCTCCAG ACTCAGCCAC ACGTGGTCAC GAGGTCTTCT ATGGGATCAT GTTTGATGCC 
GGGAGTACCG GCACCCGCAT CCACGTCTTC CAGTTTGCCC GGCCACCTGG AGAAACTCCC 
ACCTTGACCC ACGAAACCTT CAAAGCTCTG AAGCCTGGGC TTTCTGCGTA TGCCGATGAT 
GTTGAAAAGA GCGCCCAAGG GATCCAGGAG CTTCTGAATG TCGCCAAGCA ACACATTCCA 
TACGACTTCT GGAAGGCCAC CCCTCTGGTT CTCAAGGCCA CAGCTGGTCT GCGCCTGCTG 
CCGGGAGAAA AGGCTCAGAA GTTGCTGCAA AAGGTGAAGG AGGTGTTTAA GGCATCACCC 
TTCCTTGTAG GGGATGACTG TGTTTCCATC ATGAATGGCA CAGATGAAGG TGTTTCGGCT 
TGGATCACTG TCAACTTCCT GACAGGCAGT CTGAAGACCC CAGGAAGCAG CAGTGTGGGC 
ATGCTGGACT TGGGCGGAGG ATCCACTCAG ATCACCTTCC TCCCACGTGT CGAGGGTACC 
CTGCAGGCCT CCCCACCCGG CCACCTGACA GCGCTGCAGA TGTTTAACAG GACTTTCAAG 
CTGTATTCCT ACAGCTACCT GGGGCTGGGA CTGATGTCGG CACGACTGGC TATCTTGGGT 
GGTGTGGAGG GGAAACCTGC TGAGGATGAC AAGGAACTGG TCAGCCCCTG TCTGTCTCCC 
CGGTTCAGAG GAAAGTGGGA GCATGCGGAG GTCACCTATA GAATTTCAGG ACAGAAGGCA 
GTGGGCCTCT ACGAGCTGTG TGCCAGCAGG GTATCAGAAG TCCTCCGCAA TAAAGTACAC 
AGGACAGAAG AGGCGCAGCA CGTGGACTTC TATGCGTTTT CCTACTACTA CGACCTTGCT 
GCCAGCTTTG GCCTTATAGA TGCAGAGAAA GGAGGCAGCC TTGTAGTTGG AGACTTTGAG 
ATAGCAGCCA AGTATGTCTG CCGCACTCTG GAGACACAGC CTCCAAGCAG CCCCTTTGCT 
TGCATGGACC TCACCTACAT CAGCCTCCTG CTCCACGAGT TTGGTTTTCC CGGGGACAAG 
GTACTGAAGC TGGCTCGGAA AATTGACAAT GTTGAAACCA GCTGGGCTCT GGGGGCTATT 
TTTCATTACA TCGACTCCCT GAAGAGACAG AAGGTTCCTG CCTTGTAG