The following Cilk1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cilk1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | ORa01871 | |
| Clone ID Related Accession (Same CDS sequence) | NM_138886.1 | |
| Accession Version | NM_138886.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1890bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-12-24 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | serine/threonine-protein kinase ICK | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from D26178.1. ##Evidence-Data-START## Transcript exon combination :: D26178.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGAATAGAT ACACAACGAT CAAACAGCTT GGGGATGGGA CCTATGGTTC TGTCCTGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_620241.1 |
| CDS | 297..2186 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_138886.1 |
1 | ATGAATAGAT ACACAACGAT CAAACAGCTT GGGGATGGGA CCTATGGTTC TGTCCTGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | ORa43831 | |
| Clone ID Related Accession (Same CDS sequence) | XM_008766345.2 | |
| Accession Version | XM_008766345.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1890bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-07-25 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | serine/threonine-protein kinase ICK isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005107.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008766345.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGAATAGAT ACACAACGAT CAAACAGCTT GGGGATGGGA CCTATGGTTC TGTCCTGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_008764567.1 |
| CDS | 497..2386 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_008766345.2 |
1 | ATGAATAGAT ACACAACGAT CAAACAGCTT GGGGATGGGA CCTATGGTTC TGTCCTGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Intestinal cell kinase, a protein associated with endocrine-cerebro-osteodysplasia syndrome, is a key regulator of cilia length and Hedgehog signaling. |
ICK is essential for cell type-specific ciliogenesis and the regulation of ciliary transport. |
Regulation of cilium length and intraflagellar transport by the RCK-kinases ICK and MOK in renal epithelial cells. |
A multiplex human syndrome implicates a key role for intestinal cell kinase in development of central nervous, skeletal, and endocrine systems. |
Intestinal cell kinase (ICK) localizes to the crypt region and requires a dual phosphorylation site found in map kinases. |
