Mtr cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Mtr
Entrez Gene ID	81522
Full Name	5-methyltetrahydrofolate-homocysteine methyltransferase
Synonyms	methioninesynthase
General protein information	Preferred Names 5-methyltetrahydrofolate-homocysteine methyltransferase Names methionine synthase MS vitamin-B12 dependent methionine synthase
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 17 Map Location: 17q12.1
Summary	catalyzes the cobalamin-dependent conversion of 5-methyltetrahydrofolate and L-homocysteine to tetrahydrofolate and L-methionine [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_030864.1	NP_110491.1	methionine synthase

Pathways from BioSystems

Homologies

	MTR	XP_001109238.1
Rattus norvegicus (Norway rat)	Mtr	NP_110491.1
Danio rerio (zebrafish)	mtr	NP_932338.1
Xenopus tropicalis (tropical clawed frog)	LOC100488827	XP_002933914.1
Homo sapiens (human)	MTR	NP_000245.2
Canis lupus familiaris (dog)	MTR	XP_005618839.1
Caenorhabditis elegans (roundworm)	metr-1	NP_496353.1
Pan troglodytes (chimpanzee)	MTR	XP_514294.2
Mus musculus (house mouse)	Mtr	NP_001074597.1
Gallus gallus (chicken)	MTR	NP_001026275.1
Bos taurus (cattle)	MTR	NP_001025469.1

Gene Ontology
Bibliography

Related articles in PubMed

Effects of zinc deficiency and zinc supplementation on homocysteine levels and related enzyme expression in rats.
Jing M, Rech L, Wu Y, Goltz D, Taylor CG, House JD
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS)3077-82(2015 Apr)

Associations between genetic variants in folate and drug metabolizing pathways and relapse risk in pediatric acute lymphoid leukemia on CCG-1952.
Vujkovic M, Kershenbaum A, Wray L, McWilliams T, Cannon S, Devidas M, Stork L, Aplenc R
Leukemia research reports4(2)47-50(2015)

Interaction between methionine synthase isoforms and MMACHC: characterization in cblG-variant, cblG and cblC inherited causes of megaloblastic anaemia.
Fofou-Caillierez MB, Mrabet NT, Ch?ry C, Dreumont N, Flayac J, Pupavac M, Paoli J, Alberto JM, Coelho D, Camadro JM, Feillet F, Watkins D, Fowler B, Rosenblatt DS, Gu?ant JL
Human molecular genetics22(22)4591-601(2013 Nov)

S-adenosylmethionine in liver health, injury, and cancer.
Lu SC, Mato JM
Physiological reviews92(4)1515-42(2012 Oct)

Polymorphisms of MTHFR and MTR genes are not related to susceptibility to childhood ALL in North India.
Nikbakht M, MalekZadeh K, Kumar Jha A, Askari M, Marwaha RK, Kaul D, Kaur J
Experimental oncology34(1)43-8(2012)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The objective of this study was to investigate the effects of dietary Zn supply on homocysteine levels and expression of Methionine synthase and betaine-homocysteine methyltransferase in growing rats.
Title: Effects of zinc deficiency and zinc supplementation on homocysteine levels and related enzyme expression in rats.

The following Mtr gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Mtr cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa07237	NM_030864.1 Latest version!	Rattus norvegicus 5-methyltetrahydrofolate-homocysteine methyltransferase (Mtr), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$643.30 $919.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Mtr ( NM_030864.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_110491.1 Rattus norvegicus 5-methyltetrahydrofolate-homocysteine methyltransferase (Mtr), mRNA.

Price & Availability↑

CloneID	ORa07237
Clone ID Related Accession (Same CDS sequence)	NM_030864.1
Accession Version	NM_030864.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3762bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Rattus norvegicus(Norway rat)
Product	methionine synthase
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF034214.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF034214.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGAAGAAAA CCCTGCAGGA TGAGATTGAA GCCATTCTTC GGAAGAGGAT TATGGTGCTA 
GATGGCGGGA TGGGGACCAT GATCCAGCGG TACAAACTAA GCGAAGAAAA TTTCCAAGGT 
CAAGAGTTTA AAGACCACAG CAGGCCACTG AAAGGCAACA ATGACATCTT GAGTATAACT 
CAGCCTGATG TTATTTACCA GATTCATAAG GAATACTTGC TGGCTGGAGC AGACATCATT 
GAAACAAACA CTTTCAGCAG CACTAGTATC GCCCAGGCTG ACTATGGCCT CGAACACTTG 
GCCTACCGGA TGAACAAATG CTCCGCAGAC GTGGCCAGAA AAGCCGCCGA GGAGATAACT 
CTGCAGACAG GAGTCAAGAG GTTTGTGGCT GGATCTCTGG GTCCGACTAA CAAGACACTT 
TCAGTTTCCC CATCTGTGGA AAGGCCAGAT TACAGGAACA TCACATTTGA TGAGCTTGTT 
GAAGCATACC AGGAGCAGGC CAAGGGACTG CTGGATGGTG GGGTTGACAT CTTACTCATT 
GAGACGATTT TTGATACAGC CAATGCCAAA GCAGCCTTGT TTGCGCTCCA GAAACTCTTT 
GAAGAGAATT ATGCTTCTCC CAGGCCTATC TTTATTTCTG GGACCATTGT TGATAAAAGT 
GGACGGACTC TTTCTGGCCA GACAGGAGAG GCTTTTGTCA CCAGCGTGTC TCATTCAGAC 
CCCCTGTGCA TTGGATTAAA TTGTGCTCTG GGTGCAGCTG AAATGAGGCC TTTCATTGAA 
ACAATTGGAA AATGTACAAC AGCTTATGTC CTCTGTTACC CAAATGCAGG TCTTCCCAAT 
ACCTTTGGTG ATTATGATGA AACACCAGCC ATGATGGCCA TGCACCTGAA GGACTTTGCC 
GTGGACGGCT TGGTGAATGT AGTTGGTGGA TGCTGTGGTT CAACGCCTGA TCACATCAGG 
GAAATTGCAG AAGCTGTGAA AAATTGTAAG CCAAGAGTTC CCCCTGATAG TGTTTTTGAA 
GGACATATGT TACTGTCTGG TCTAGAGCCC TTCAGGATTG GACCATACAC TAACTTTGTT 
AACATTGGAG AGCGCTGTAA CGTGGCAGGA TCCAAGAAAT TTGCTAAGCT CATCATGGCA 
GGAAACTATG AAGAAGCCCT GAGCGTTGCC AAAGTGCAGG TGGAAATGGG AGCTCAGGTG 
CTGGATATCA ACATGGATGA CGGCATGCTG GATGGTCCCA GTGCGATGAC CAAATTTTGC 
AACTTCATTG CTTCGGAGCC TGACATTGCC AAGGTGCCCC TGTGCATTGA CTCTTCCAAT 
TTTGCTGTGA TCGAGGCGGG GTTGAAGTGC TGCCAAGGGA AGTGCATAGT CAACAGCATC 
AGCCTGAAGG AGGGGGAGGA GGACTTCCTG GAGAAGGCCA GGAAGATTAA GAAGTTTGGA 
GCTGCTGTGG TGGTTATGGC TTTTGATGAG GAAGGACAGG CAACAGAAAC AGATGTTAAA 
GTCAGTGTGT GCACTAGAGC CTACCATCTA CTTGTGGAAA AAGTGGGCTT CAATCCAAAT 
GATATCATCT TTGACCCCAA CATCCTTACC ATTGGAACTG GAATGGAAGA ACATAACTTG 
TATGCTATCA ATTTTATTCA TGCAACGAGA GTCATTAAGG AAACATTACC AGGAGTCAGA 
ATAAGTGGAG GTCTCTCCAA CCTATCCTTC GCCTTCCGAG GGATGGACGC CATTCGAGAA 
GCAATGCACG GTGTTTTCCT TTATCATGCA ATCAAGTTCG GTATGGACAT GGGGATAGTC 
AATGCCGGCA GTCTCCCCGT GTACGATGAT ATCCATAAGG ACCTTCTTCA GCTCTGTGAA 
GACCTCATCT GGAACAGAGA CGCTGAGGCT ACTGAGAAAC TCTTACGATA TGCCCAGACT 
CATGGCAAAG GAGGGAAGAA AGTCATCCAG ACAGATGAGT GGAGGAATGG CTCGATTGAA 
GAGCGCCTGG AGTATGCTCT TGTGAAGGGC ATTGAAAAGC ACATTGTTGA AGACACTGAA 
GAAGCCAGGT TAAACCGGGA AAAATACCCC CGGCCTCTGA ATATAATTGA AGGGCCCCTG 
ATGAATGGCA TGAAAGTGGT TGGTGATCTT TTTGGAGCTG GAAAAATGTT TCTACCTCAG 
GTTATAAAGT CAGCCCGTGT CATGAAGAAG GCTGTTGGCC ACCTTATCCC TTTCATGGAA 
AAAGAAAGAG AAGAAGCCAG GGTGCTTAAT GGTTCGGTTG AAGAAGAGGA CCCTTACCAA 
GGCACCATTG TGCTGGCCAC TGTTAAAGGT GATGTGCATG ACATTGGCAA GAACATTGTT 
GGTGTGGTGC TGGGCTGTAA TAATTTCAGA GTTATTGATT TAGGAGTCAT GACTCCCTGT 
GATAAGATAC TTCAAGCTGC TCTGGACCAC AAAGCAGATA TAATTGGCTT GTCAGGACTT 
ATCACGCCAT CCTTGGATGA AATGATTTTT GTTGCCAAGG AAATGGAGAG GTTGGCTATA 
AAGATTCCAT TGTTGATAGG AGGAGCAACC ACTTCAAGAA CCCACACAGC AGTTAAAATA 
GCACCACGGT ACAGTGCGCC TGTAATCCAT GTTCTAGATG CATCCAAGAG TGTGGTGGTG 
TGTTCTCAGC TGTTAGATGA AAATCTGAAA GATGACTACT TTGAAGAAAT ACTGGAAGAG 
TATGAAGATA TTAGACAGGA CCACTACGAG TCTCTCAAAG AGAGAAAATA CTTACCCCTA 
AGTCAAGCCA GAAAACACAG TTTCCACATT GATTGGCTGT CTGAACCTCA CCCAGTGAAG 
CCCACGTTTA TTGGGACCCA GGTCTTTGAA GACTACAACC TGCAAAAGCT GGTGGACTAC 
ATTGACTGGA AGCCTTTCTT TGATGTCTGG CAGCTCCGCG GCAAGTACCC GAACCGAGGA 
TTTCCCAAGA TATTCAATGA CAAAGCAGTA GGTGAAGAAG CCAGAAAGGT ATATGAGGAT 
GCTCAGAACA TGCTGAGCAT ACTGATCAGT CGAAAGAAAC TCCGGGCCAG GGGTGTGGTT 
GGATTCTGGC CAGCACAGAG CGTCCAAGAT GACATCCACC TGTATGCAGA GGGGGCGGTG 
CCCCAGGCCG CCGAGCCCAT AGCCACCTTC TATGGACTGA GGCAGCAGGC TGAGAAGGAC 
TCCTCCAGTA CAGACCCCTA CCACTGCCTC TCAGACTTCG TTGCTCCTCT GCATTCTGGT 
GTCCGTGACT ACTTGGGTCT GTTTGCTGTG GCCTGCTTTG GGGTTGAAGA GCTGAGTAAG 
GCCTATGAGG ATGATGGCGA TGACTACAGC AGCATCATGG TGAAGGCCCT GGGGGACAGG 
CTGGCGGAGG CCTTTGCAGA GGAGCTCCAC GAGAGAGTGC GCAGAGAACT CTGGGCTTAC 
TGTGGGAGTG AGCAGTTGGG TGTCACAGAC TTGCGCAAAC TCCGCTATGA GGGCATCCGG 
CCAGCTCCTG GTTACCCCAG CCAGCCTGAC CATACCGAGA AGCTCACCAT GTGGAGGCTG 
GCCAACATCG AGCAGGCCAC AGGCATCAGG TTGACAGAAT CCTTGGCAAT GGCACCTGCT 
TCAGCAGTGT CGGGTCTCTA CTTCTCCAAT GTAAAGTCCA AATATTTTGC TGTGGGGAAA 
ATTTCCAAAG ATCAGATTGA GGATTATGCC TTGAGGAAGA ACATGTCAGT GGCCGAGGTG 
GAAAAATGGC TTGGCCCCAT TCTGGGATAT GATACAGACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_110491.1
CDS	284..4045
Translation	MKKTLQDEIEAILRKRIMVLDGGMGTMIQRYKLSEENFQGQEFKDHSRPLKGNNDILSITQPDVIYQIHKEYLLAGADIIETNTFSSTSIAQADYGLEHLAYRMNKCSADVARKAAEEITLQTGVKRFVAGSLGPTNKTLSVSPSVERPDYRNITFDELVEAYQEQAKGLLDGGVDILLIETIFDTANAKAALFALQKLFEENYASPRPIFISGTIVDKSGRTLSGQTGEAFVTSVSHSDPLCIGLNCALGAAEMRPFIETIGKCTTAYVLCYPNAGLPNTFGDYDETPAMMAMHLKDFAVDGLVNVVGGCCGSTPDHIREIAEAVKNCKPRVPPDSVFEGHMLLSGLEPFRIGPYTNFVNIGERCNVAGSKKFAKLIMAGNYEEALSVAKVQVEMGAQVLDINMDDGMLDGPSAMTKFCNFIASEPDIAKVPLCIDSSNFAVIEAGLKCCQGKCIVNSISLKEGEEDFLEKARKIKKFGAAVVVMAFDEEGQATETDVKVSVCTRAYHLLVEKVGFNPNDIIFDPNILTIGTGMEEHNLYAINFIHATRVIKETLPGVRISGGLSNLSFAFRGMDAIREAMHGVFLYHAIKFGMDMGIVNAGSLPVYDDIHKDLLQLCEDLIWNRDAEATEKLLRYAQTHGKGGKKVIQTDEWRNGSIEERLEYALVKGIEKHIVEDTEEARLNREKYPRPLNIIEGPLMNGMKVVGDLFGAGKMFLPQVIKSARVMKKAVGHLIPFMEKEREEARVLNGSVEEEDPYQGTIVLATVKGDVHDIGKNIVGVVLGCNNFRVIDLGVMTPCDKILQAALDHKADIIGLSGLITPSLDEMIFVAKEMERLAIKIPLLIGGATTSRTHTAVKIAPRYSAPVIHVLDASKSVVVCSQLLDENLKDDYFEEILEEYEDIRQDHYESLKERKYLPLSQARKHSFHIDWLSEPHPVKPTFIGTQVFEDYNLQKLVDYIDWKPFFDVWQLRGKYPNRGFPKIFNDKAVGEEARKVYEDAQNMLSILISRKKLRARGVVGFWPAQSVQDDIHLYAEGAVPQAAEPIATFYGLRQQAEKDSSSTDPYHCLSDFVAPLHSGVRDYLGLFAVACFGVEELSKAYEDDGDDYSSIMVKALGDRLAEAFAEELHERVRRELWAYCGSEQLGVTDLRKLRYEGIRPAPGYPSQPDHTEKLTMWRLANIEQATGIRLTESLAMAPASAVSGLYFSNVKSKYFAVGKISKDQIEDYALRKNMSVAEVEKWLGPILGYDTD

Target ORF information:

RefSeq Version	NM_030864.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus 5-methyltetrahydrofolate-homocysteine methyltransferase (Mtr), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_030864.1

ORF Insert Sequence:

ATGAAGAAAA CCCTGCAGGA TGAGATTGAA GCCATTCTTC GGAAGAGGAT TATGGTGCTA 
GATGGCGGGA TGGGGACCAT GATCCAGCGG TACAAACTAA GCGAAGAAAA TTTCCAAGGT 
CAAGAGTTTA AAGACCACAG CAGGCCACTG AAAGGCAACA ATGACATCTT GAGTATAACT 
CAGCCTGATG TTATTTACCA GATTCATAAG GAATACTTGC TGGCTGGAGC AGACATCATT 
GAAACAAACA CTTTCAGCAG CACTAGTATC GCCCAGGCTG ACTATGGCCT CGAACACTTG 
GCCTACCGGA TGAACAAATG CTCCGCAGAC GTGGCCAGAA AAGCCGCCGA GGAGATAACT 
CTGCAGACAG GAGTCAAGAG GTTTGTGGCT GGATCTCTGG GTCCGACTAA CAAGACACTT 
TCAGTTTCCC CATCTGTGGA AAGGCCAGAT TACAGGAACA TCACATTTGA TGAGCTTGTT 
GAAGCATACC AGGAGCAGGC CAAGGGACTG CTGGATGGTG GGGTTGACAT CTTACTCATT 
GAGACGATTT TTGATACAGC CAATGCCAAA GCAGCCTTGT TTGCGCTCCA GAAACTCTTT 
GAAGAGAATT ATGCTTCTCC CAGGCCTATC TTTATTTCTG GGACCATTGT TGATAAAAGT 
GGACGGACTC TTTCTGGCCA GACAGGAGAG GCTTTTGTCA CCAGCGTGTC TCATTCAGAC 
CCCCTGTGCA TTGGATTAAA TTGTGCTCTG GGTGCAGCTG AAATGAGGCC TTTCATTGAA 
ACAATTGGAA AATGTACAAC AGCTTATGTC CTCTGTTACC CAAATGCAGG TCTTCCCAAT 
ACCTTTGGTG ATTATGATGA AACACCAGCC ATGATGGCCA TGCACCTGAA GGACTTTGCC 
GTGGACGGCT TGGTGAATGT AGTTGGTGGA TGCTGTGGTT CAACGCCTGA TCACATCAGG 
GAAATTGCAG AAGCTGTGAA AAATTGTAAG CCAAGAGTTC CCCCTGATAG TGTTTTTGAA 
GGACATATGT TACTGTCTGG TCTAGAGCCC TTCAGGATTG GACCATACAC TAACTTTGTT 
AACATTGGAG AGCGCTGTAA CGTGGCAGGA TCCAAGAAAT TTGCTAAGCT CATCATGGCA 
GGAAACTATG AAGAAGCCCT GAGCGTTGCC AAAGTGCAGG TGGAAATGGG AGCTCAGGTG 
CTGGATATCA ACATGGATGA CGGCATGCTG GATGGTCCCA GTGCGATGAC CAAATTTTGC 
AACTTCATTG CTTCGGAGCC TGACATTGCC AAGGTGCCCC TGTGCATTGA CTCTTCCAAT 
TTTGCTGTGA TCGAGGCGGG GTTGAAGTGC TGCCAAGGGA AGTGCATAGT CAACAGCATC 
AGCCTGAAGG AGGGGGAGGA GGACTTCCTG GAGAAGGCCA GGAAGATTAA GAAGTTTGGA 
GCTGCTGTGG TGGTTATGGC TTTTGATGAG GAAGGACAGG CAACAGAAAC AGATGTTAAA 
GTCAGTGTGT GCACTAGAGC CTACCATCTA CTTGTGGAAA AAGTGGGCTT CAATCCAAAT 
GATATCATCT TTGACCCCAA CATCCTTACC ATTGGAACTG GAATGGAAGA ACATAACTTG 
TATGCTATCA ATTTTATTCA TGCAACGAGA GTCATTAAGG AAACATTACC AGGAGTCAGA 
ATAAGTGGAG GTCTCTCCAA CCTATCCTTC GCCTTCCGAG GGATGGACGC CATTCGAGAA 
GCAATGCACG GTGTTTTCCT TTATCATGCA ATCAAGTTCG GTATGGACAT GGGGATAGTC 
AATGCCGGCA GTCTCCCCGT GTACGATGAT ATCCATAAGG ACCTTCTTCA GCTCTGTGAA 
GACCTCATCT GGAACAGAGA CGCTGAGGCT ACTGAGAAAC TCTTACGATA TGCCCAGACT 
CATGGCAAAG GAGGGAAGAA AGTCATCCAG ACAGATGAGT GGAGGAATGG CTCGATTGAA 
GAGCGCCTGG AGTATGCTCT TGTGAAGGGC ATTGAAAAGC ACATTGTTGA AGACACTGAA 
GAAGCCAGGT TAAACCGGGA AAAATACCCC CGGCCTCTGA ATATAATTGA AGGGCCCCTG 
ATGAATGGCA TGAAAGTGGT TGGTGATCTT TTTGGAGCTG GAAAAATGTT TCTACCTCAG 
GTTATAAAGT CAGCCCGTGT CATGAAGAAG GCTGTTGGCC ACCTTATCCC TTTCATGGAA 
AAAGAAAGAG AAGAAGCCAG GGTGCTTAAT GGTTCGGTTG AAGAAGAGGA CCCTTACCAA 
GGCACCATTG TGCTGGCCAC TGTTAAAGGT GATGTGCATG ACATTGGCAA GAACATTGTT 
GGTGTGGTGC TGGGCTGTAA TAATTTCAGA GTTATTGATT TAGGAGTCAT GACTCCCTGT 
GATAAGATAC TTCAAGCTGC TCTGGACCAC AAAGCAGATA TAATTGGCTT GTCAGGACTT 
ATCACGCCAT CCTTGGATGA AATGATTTTT GTTGCCAAGG AAATGGAGAG GTTGGCTATA 
AAGATTCCAT TGTTGATAGG AGGAGCAACC ACTTCAAGAA CCCACACAGC AGTTAAAATA 
GCACCACGGT ACAGTGCGCC TGTAATCCAT GTTCTAGATG CATCCAAGAG TGTGGTGGTG 
TGTTCTCAGC TGTTAGATGA AAATCTGAAA GATGACTACT TTGAAGAAAT ACTGGAAGAG 
TATGAAGATA TTAGACAGGA CCACTACGAG TCTCTCAAAG AGAGAAAATA CTTACCCCTA 
AGTCAAGCCA GAAAACACAG TTTCCACATT GATTGGCTGT CTGAACCTCA CCCAGTGAAG 
CCCACGTTTA TTGGGACCCA GGTCTTTGAA GACTACAACC TGCAAAAGCT GGTGGACTAC 
ATTGACTGGA AGCCTTTCTT TGATGTCTGG CAGCTCCGCG GCAAGTACCC GAACCGAGGA 
TTTCCCAAGA TATTCAATGA CAAAGCAGTA GGTGAAGAAG CCAGAAAGGT ATATGAGGAT 
GCTCAGAACA TGCTGAGCAT ACTGATCAGT CGAAAGAAAC TCCGGGCCAG GGGTGTGGTT 
GGATTCTGGC CAGCACAGAG CGTCCAAGAT GACATCCACC TGTATGCAGA GGGGGCGGTG 
CCCCAGGCCG CCGAGCCCAT AGCCACCTTC TATGGACTGA GGCAGCAGGC TGAGAAGGAC 
TCCTCCAGTA CAGACCCCTA CCACTGCCTC TCAGACTTCG TTGCTCCTCT GCATTCTGGT 
GTCCGTGACT ACTTGGGTCT GTTTGCTGTG GCCTGCTTTG GGGTTGAAGA GCTGAGTAAG 
GCCTATGAGG ATGATGGCGA TGACTACAGC AGCATCATGG TGAAGGCCCT GGGGGACAGG 
CTGGCGGAGG CCTTTGCAGA GGAGCTCCAC GAGAGAGTGC GCAGAGAACT CTGGGCTTAC 
TGTGGGAGTG AGCAGTTGGG TGTCACAGAC TTGCGCAAAC TCCGCTATGA GGGCATCCGG 
CCAGCTCCTG GTTACCCCAG CCAGCCTGAC CATACCGAGA AGCTCACCAT GTGGAGGCTG 
GCCAACATCG AGCAGGCCAC AGGCATCAGG TTGACAGAAT CCTTGGCAAT GGCACCTGCT 
TCAGCAGTGT CGGGTCTCTA CTTCTCCAAT GTAAAGTCCA AATATTTTGC TGTGGGGAAA 
ATTTCCAAAG ATCAGATTGA GGATTATGCC TTGAGGAAGA ACATGTCAGT GGCCGAGGTG 
GAAAAATGGC TTGGCCCCAT TCTGGGATAT GATACAGACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Effects of zinc deficiency and zinc supplementation on homocysteine levels and related enzyme expression in rats.
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS)3077-82(2015 Apr)
Jing M,Rech L,Wu Y,Goltz D,Taylor CG,House JD

Associations between genetic variants in folate and drug metabolizing pathways and relapse risk in pediatric acute lymphoid leukemia on CCG-1952.
Leukemia research reports4(2)47-50(2015)
Vujkovic M,Kershenbaum A,Wray L,McWilliams T,Cannon S,Devidas M,Stork L,Aplenc R

Interaction between methionine synthase isoforms and MMACHC: characterization in cblG-variant, cblG and cblC inherited causes of megaloblastic anaemia.
Human molecular genetics22(22)4591-601(2013 Nov)
Fofou-Caillierez MB,Mrabet NT,Ch?ry C,Dreumont N,Flayac J,Pupavac M,Paoli J,Alberto JM,Coelho D,Camadro JM,Feillet F,Watkins D,Fowler B,Rosenblatt DS,Gu?ant JL

S-adenosylmethionine in liver health, injury, and cancer.
Physiological reviews92(4)1515-42(2012 Oct)
Lu SC,Mato JM

Polymorphisms of MTHFR and MTR genes are not related to susceptibility to childhood ALL in North India.
Experimental oncology34(1)43-8(2012)
Nikbakht M,MalekZadeh K,Kumar Jha A,Askari M,Marwaha RK,Kaul D,Kaur J