Msn cDNA ORF clone, Rattus norvegicus(Norway rat)

X-linked primary immunodeficiency associated with hemizygous mutations in the moesin (MSN) gene.
Lagresle-Peyrou C, Luce S, Ouchani F, Soheili TS, Sadek H, Chouteau M, Durand A, Pic I, Majewski J, Brouzes C, Lambert N, Bohineust A, Verhoeyen E, Cosset FL, Magerus-Chatinet A, Rieux-Laucat F, Gandemer V, Monnier D, Heijmans C, van Gijn M, Dalm VA, Mahlaoui N, Stephan JL, Picard C, Durandy A, Kracker S, Hivroz C, Jabado N, de Saint Basile G, Fischer A, Cavazzana M, Andr?-Schmutz I
The Journal of allergy and clinical immunology138(6)1681-1689.e8(2016 Dec)

Moesin is activated in cardiomyocytes in experimental autoimmune myocarditis and mediates cytoskeletal reorganization with protrusion formation.
Miyawaki A, Mitsuhara Y, Orimoto A, Nakayasu Y, Tsunoda S, Obana M, Maeda M, Nakayama H, Yoshioka Y, Tsutsumi Y, Fujio Y
American journal of physiology. Heart and circulatory physiology311(2)H476-86(2016 Aug)

Podoplanin mediates ECM degradation by squamous carcinoma cells through control of invadopodia stability.
Mart?n-Villar E, Borda-d'Agua B, Carrasco-Ramirez P, Renart J, Parsons M, Quintanilla M, Jones GE
Oncogene34(34)4531-44(2015 Aug)

[The transfection of lentiviral siRNA vectors targeting ezrin, radixin and moesin facilitates influenza virus replication in primary pulmonary microvascular endothelial cells].
Wu Y, Zhang S, Zhang C, Xuan Z, Li S, Gao Y, Hu Y
Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology31(4)456-61(2015 Apr)

NHERF1/EBP50 controls morphogenesis of 3D colonic glands by stabilizing PTEN and ezrin-radixin-moesin proteins at the apical membrane.
Georgescu MM, Cote G, Agarwal NK, White CL 3rd
Neoplasia (New York, N.Y.)16(4)365-74.e1-2(2014 Apr)

The expression of moesin was upregulated in cardiomyocytes under inflammation, inducing protrusion formation in a phosphorylation-dependent fashion.
Title: Moesin is activated in cardiomyocytes in experimental autoimmune myocarditis and mediates cytoskeletal reorganization with protrusion formation.

Overexpression ezrin, radixin and moesin facilitates influenza virus H1N1 replication in primary pulmonary microvascular endothelial cells.
Title: [The transfection of lentiviral siRNA vectors targeting ezrin, radixin and moesin facilitates influenza virus replication in primary pulmonary microvascular endothelial cells].

These results indicate that ezrin, radixin, and moesin exert a redundant control on platelet derived growth factor-induced vascular smooth muscle cells migration by regulating focal adhesion turn-over and cell adhesion to substrate.
Title: Redundant control of migration and adhesion by ERM proteins in vascular smooth muscle cells.

Found that moesin knock-down does not affect renal Na(+) -K(+) -2Cl(-) co-transporter internalisation but strongly reduces exocytosis of the co-transporter.
Title: Identification of moesin as NKCC2-interacting protein and analysis of its functional role in the NKCC2 apical trafficking.

The ERM (ezrin, radixin, moesin) proteins are novel scaffolds at the level of SOS activity control, which is relevant for both normal Ras function and dysfunction known to occur in several human cancers.
Title: Activation of Ras requires the ERM-dependent link of actin to the plasma membrane.