Inppl1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Inppl1
Entrez Gene ID	65038
Full Name	inositol polyphosphate phosphatase-like 1
Synonyms	Ship2
General protein information	Preferred Names inositol polyphosphate phosphatase-like 1 Names phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 INPPL-1 SH2 domain-containing inositol 5'-phosphatase 2 SH2 domain-containing inositol phosphatase 2 SH2-containing inositol phosphatase 2 SHIP-2 inositol polyphosphate phosphatase-like protein 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q32
Summary	phosphatase that plays a negative regulatory role in insulin-induced mitogenesis [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001270843.1	NP_001257772.1	phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform 2
NM_022944.2	NP_075233.1	phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform 1

Pathways from BioSystems

Homologies

Homo sapiens (human)	INPPL1	NP_001558.3
Pan troglodytes (chimpanzee)	INPPL1	XP_508622.2
	INPPL1	XP_001114794.1
Mus musculus (house mouse)	Inppl1	NP_001116211.1
Canis lupus familiaris (dog)	INPPL1	XP_542327.2
Bos taurus (cattle)	INPPL1	NP_001178105.1
Rattus norvegicus (Norway rat)	Inppl1	NP_075233.1
Danio rerio (zebrafish)	inppl1a	NP_001034893.1

Gene Ontology
Bibliography

Related articles in PubMed

Exome sequencing identifies INPPL1 mutations as a cause of opsismodysplasia.
Huber C, Faqeih EA, Bartholdi D, Bole-Feysot C, Borochowitz Z, Cavalcanti DP, Frigo A, Nitschke P, Roume J, Santos HG, Shalev SA, Superti-Furga A, Delezoide AL, Le Merrer M, Munnich A, Cormier-Daire V
American journal of human genetics92(1)144-9(2013 Jan)

Regulation of insulin signaling and glucose transporter 4 (GLUT4) exocytosis by phosphatidylinositol 3,4,5-trisphosphate (PIP3) phosphatase, skeletal muscle, and kidney enriched inositol polyphosphate phosphatase (SKIP).
Ijuin T, Takenawa T
The Journal of biological chemistry287(10)6991-9(2012 Mar)

SH3YL1 regulates dorsal ruffle formation by a novel phosphoinositide-binding domain.
Hasegawa J, Tokuda E, Tenno T, Tsujita K, Sawai H, Hiroaki H, Takenawa T, Itoh T
The Journal of cell biology193(5)901-16(2011 May)

Serum withdrawal-induced accumulation of phosphoinositide 3-kinase lipids in differentiating 3T3-L6 myoblasts: distinct roles for Ship2 and PTEN.
Mandl A, Sarkes D, Carricaburu V, Jung V, Rameh L
Molecular and cellular biology27(23)8098-112(2007 Dec)

An essential role for the SHIP2-dependent negative feedback loop in neuritogenesis of nerve growth factor-stimulated PC12 cells.
Aoki K, Nakamura T, Inoue T, Meyer T, Matsuda M
The Journal of cell biology177(5)817-27(2007 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Regulation of insulin signaling and glucose transporter 4 (GLUT4) exocytosis by phosphatidylinositol 3,4,5-trisphosphate (PIP3) phosphatase, skeletal muscle, and kidney enriched inositol polyphosphate phosphatase (SKIP).
Title: Regulation of insulin signaling and glucose transporter 4 (GLUT4) exocytosis by phosphatidylinositol 3,4,5-trisphosphate (PIP3) phosphatase, skeletal muscle, and kidney enriched inositol polyphosphate phosphatase (SKIP).

These results reveal the existence of two distinct pools of PI3K lipids in myoblasts: a pool dephosphorylated by PTEN, capable of activating Akt and promoting myoblast differentiation and a stable pool dephosphorylated by Ship2 and unable to activate Akt.
Title: Serum withdrawal-induced accumulation of phosphoinositide 3-kinase lipids in differentiating 3T3-L6 myoblasts: distinct roles for Ship2 and PTEN.

SHIP2-mediated negative feedback on PIP(3) coordinately works with the PI3-kinase-mediated positive feedback to maintain proper neurite outgrowth.
Title: An essential role for the SHIP2-dependent negative feedback loop in neuritogenesis of nerve growth factor-stimulated PC12 cells.

Hepatic SHIP2 has an impact in vivo on the glucose metabolism in both physiological states possibly by regulating hepatic gene expression, when tranfected into mice.
Title: Impact of the liver-specific expression of SHIP2 (SH2-containing inositol 5'-phosphatase 2) on insulin signaling and glucose metabolism in mice.

SHIP2 regulates PDGF- and IGF-I-mediated signaling downstream of PI3-kinase, leading to the antiapoptotic effect via 5-phosphatase activity, and regulates the growth factor-induced Ras-MAPK pathway mainly via the SH2 domain.
Title: Dual role of SRC homology domain 2-containing inositol phosphatase 2 in the regulation of platelet-derived growth factor and insulin-like growth factor I signaling in rat vascular smooth muscle cells.

The following Inppl1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Inppl1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa06487	NM_022944.2 Latest version!	Rattus norvegicus inositol polyphosphate phosphatase-like 1 (Inppl1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$923.30 $1319.00
ORa09872	NM_001270843.1 Latest version!	Rattus norvegicus inositol polyphosphate phosphatase-like 1 (Inppl1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$643.30 $919.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Inppl1 ( NM_022944.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_075233.1 Rattus norvegicus inositol polyphosphate phosphatase-like 1 (Inppl1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	ORa06487
Clone ID Related Accession (Same CDS sequence)	NM_022944.2
Accession Version	NM_022944.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3774bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-21
Organism	Rattus norvegicus(Norway rat)
Product	phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AB025794.1, FQ139232.1, CK653108.1, AB011439.1, BQ199460.1 and CA506674.1. On Aug 3, 2012 this sequence version replaced NM_022944.1. Transcript Variant: This variant (1) encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB025794.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGCCTCAG TGTGTGGGGC ACCGAGTCCC GGGGGCGCGC TAGGCAGCCA GGCCCCTGCC 
TGGTATCACC GTGACCTGAG CCGCGCGGCT GCGGAGGAGC TGCTAGCTCG GGCAGGCCGC 
GATGGCAGCT TCCTGGTGCG AGACAGCGAG AGCGTGGCGG GGGCCTTCGC ACTCTGCGTC 
CTGTATCAAA AGCACGTGCA CACCTACCGC ATTCTGCCAG ATGGAGAGGA TTTCCTGGCT 
GTGCAGACCT CACAGGGCGT TCCTGTGCGC CGCTTCCAGA CCCTGGGTGA GCTTATAGGC 
CTGTATGCCC AGCCCAACCA GGGTCTTGTC TGTGCTCTGC TGCTGCCTGT AGAGGGGGAG 
AGAGAGCCAG ATCCACCGGA TGACCGAGAT GCCTCAGATG TGGAGGACGA GAAACCCCCA 
CTACCCCCGC GCTCTGGCTC TACCAGCATT TCTGTCCCTG CGGGGCCTAG CAGCCCCCTG 
CCAGCCCCTG AGACTCCCAC AACTCCAGCA GCTGAGAGCA CTCCTAATGG ACTCAGCACT 
GTGTCACATG AGTATCTGAA GGGCAGCTAC GGGCTGGACC TGGAGGCTGT ACGAGGCGGA 
GCCAGCAACT TGCCCCATCT CACCCGAACC CTTGTCACCT CATGCCGTAG GCTACACAGC 
GAGGTGGACA AGGTCCTGTC AGGCCTAGAG ATCCTGTCGA AGGTGTTTGA CCAGCAGAGC 
TCACCCATGG TGACCCGCCT TTTGCAGCAG CAGAGCCTAC CACAGACTGG AGAGCAAGAG 
TTGGAGAGCC TTGTGCTGAA GCTATCTGTG CTAAAGGACT TCCTGTCAGG CATCCAGAAG 
AAGGCCCTAA AGGCACTGCA GGACATGAGC TCCACAGCAC CTCCGGCTCC ATTGCAGCCC 
TCCATACGAA AGGCCAAGAC CATCCCTGTG CAAGCCTTTG AGGTGAAGCT GGATGTGACA 
CTGGGTGACC TGACCAAGAT CGGGAAGTCC CAGAAGTTCA CACTGAGCGT GGATGTGGAG 
GGTGGGAGGC TGGTACTGCT GAGGAGACAG CGTGACTCCC AGGAGGACTG GACGACCTTC 
ACACACGACC GGATCCGGCA GCTCATTAAA TCCCAGCGTG TGCAGAACAA GCTGGGTGTT 
GTGTTTGAAA AGGAGAAAGA TCGGACGCAG CGCAAGGACT TCATCTTTGT CAGTGCCCGG 
AAGCGAGAAG CCTTCTGCCA GCTTCTGCAG CTCATGAAGA ACAAGCATTC CAAGCAGGAT 
GAACCTGACA TGATCTCCGT CTTCATAGGC ACCTGGAACA TGGGAAGTGT ACCACCACCA 
AAAAACGTGA CATCTTGGTT CACATCAAAG GGACTGGGGA AAGCCCTGGA TGAGGTCACA 
GTGACTATAC CCCACGATAT CTATGTCTTT GGGACTCAGG AGAACTCAGT GGGTGACAGA 
GAGTGGCTGG ATCTGCTGCG TGGGGGCCTC AAGGAGCTTA CAGATCTGGA TTACCGTCCG 
ATTGCTATGC AGTCACTGTG GAACATCAAG GTGGCCGTGC TGGTCAAGCC AGAACATGAG 
AACCGCATCA GCCACGTTAG TACGTCCAGT GTGAAGACTG GTATCGCCAA TACCCTGGGG 
AACAAGGGAG CTGTGGGTGT TTCCTTCATG TTCAATGGCA CTTCTTTTGG CTTCGTGAAT 
TGCCATCTCA CCTCAGGGAA TGAGAAGACT ACTCGGCGGA ACCAGAATTA TCTGGACATC 
CTGCGTCTTC TCTCATTGGG TGATCGGCAG CTCAGTGCCT TTGACATCTC TTTGAGGTTC 
ACTCATCTCT TCTGGTTTGG GGACCTTAAC TACCGCTTAG ACATGGATAT CCAGGAGATC 
CTGAACTACA TTAGTAGGAG AGAGTTTGAG CCCCTGCTCA GGGTGGACCA GCTCAACCTG 
GAGCGGGAGA AGCATAAGGT CTTCCTTCGA TTTAGTGAGG AGGAGATATC TTTCCCACCC 
ACCTACCGCT ACGAGCGGGG TTCCCGAGAC ACATATGCTT GGCACAAGCA GAAGCCAACT 
GGGGTCCGGA CCAATGTGCC TTCATGGTGT GACCGGATTC TATGGAAATC CTATCCTGAA 
ACCCACATCA TCTGCAATTC CTATGGTTGC ACTGATGACA TTGTTACCAG TGACCATTCT 
CCTGTGTTTG GGACATTTGA GGTTGGAGTG ACTTCCCAGT TCATCTCCAA GAAAGGTCTC 
TCTAAGACCT CAGACCAGGC CTACATTGAG TTTGAGAGCA TCGAGGCCAT CGTGAAGACG 
GCCAGCCGCA CCAAGTTCTT CATTGAGTTC TATTCTACCT GCTTGGAAGA GTACAAGAAG 
AGCTTCGAGA ATGACGCTCA GAGCAGTGAC AACATCAATT TCCTCAAGGT GCAGTGGTCC 
TCGCGCCAGC TGCCCACGCT CAAGCCAATT CTGGCTGACA TTGAGTACCT GCAGGATCAG 
CATCTCCTGC TCACAGTCAA GTCCATGGAT GGCTACGAAT CATATGGGGA GTGTGTGGTT 
GCACTCAAAT CCATGATTGG CAGCACGGCC CAGCAGTTCT TGACCTTCTT GTCCCACCGT 
GGAGAGGAGA CAGGCAACAT TCGTGGCTCC ATGAAGGTGC GGGTGCCCAC AGAACGCCTG 
GGCACCCGTG AGCGGCTCTA TGAATGGATT AGCATTGATA AGGATGACAC AGGAGCCAAA 
AGCAAGGCTC CTTCAGTGTT GCGGGGCAGC CAGGAGCACA GATCTGGGAG CCGCAAGCCA 
ACTTCCACAG AGGCCTCCTG TCCACTGTCC AAGTTGTTTG AAGAGCCTGA AAAGCCACCA 
CCGACTGGCA GGCCCCCAGC CCCACCACGG GCAGTTCCTA GGGAGGAGTC CTTGAACCCC 
AGGTTGAAGT CAGAGGGGAC ACCTGAACAG GAAGGAGTAG CAGCCCCTCC ACCCAAGAAC 
AGCTTCAATA ACCCTGCCTA CTACGTCCTT GAAGGGGTCC CACATCAGCT GCTGCCCCTG 
GAGCCAACCT CATTTGCCAG GGCCCCTATC CCACCTACCA CCAAGAACAA AGTGGCCATC 
ACAGTGCCTG CTCCTCAGCT TGGGCGCCAC CGGACCCCTC GTGTGGGGGA GGGAAGCTCT 
TCGGATGAGG ACTCTGGGGG CACACTGCCT CCTCCAGACT TCCCACCTCC ACCACTGCCA 
GACTCAGCCA TCTTCCTGCC CCCTAACCTG GATCCTTTAT CAATGCCAGT GGTCAGGGGC 
CGAAGTGTGG GTGAGGCCCG TGGCCCACCA CCTCCCAAGG CCCATCCAAG ACCACCACTA 
CCGCCGGGCA CCTCACCTGC CAGTACTTTT TTGGAAGAGG TTGCAAGTGC GGATGACCGG 
TCTTGCTCAG TACTGCAGAT GGCCAAGACA CTCAGTGAGG TAGATTATTC TCCTGGGCCT 
GGACGCTCAG CACTCCTCCC CAACCCCTTG GAATTGCAGC TTCCCCGAGG GCCCTCGGAC 
TACGGACGAC CCCTCAGCTT CCCTCCACCC CGCATCCGGG AGAGCATCCA AGAAGACTTG 
GCAGAGGAGG CTCCGTGCCC GCAGGGCGGG CGGGCCAGCG GGCTGGGAGA GGCGGGCATG 
GGTGCCTGGC TGCGGGCCAT CGGCTTGGAG CGCTATGAGG AGGGCCTGGT GCACAATGGC 
TGGGACGACC TGGAGTTTCT CAGTGACATC ACTGAGGAAG ACCTCGAGGA AGCTGGGGTG 
CAGGATCCTG CTCACAAGCG CCTTCTTCTG GACACGCTGC AGCTCAGCAA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_075233.1
CDS	288..4061
Translation	MASVCGAPSPGGALGSQAPAWYHRDLSRAAAEELLARAGRDGSFLVRDSESVAGAFALCVLYQKHVHTYRILPDGEDFLAVQTSQGVPVRRFQTLGELIGLYAQPNQGLVCALLLPVEGEREPDPPDDRDASDVEDEKPPLPPRSGSTSISVPAGPSSPLPAPETPTTPAAESTPNGLSTVSHEYLKGSYGLDLEAVRGGASNLPHLTRTLVTSCRRLHSEVDKVLSGLEILSKVFDQQSSPMVTRLLQQQSLPQTGEQELESLVLKLSVLKDFLSGIQKKALKALQDMSSTAPPAPLQPSIRKAKTIPVQAFEVKLDVTLGDLTKIGKSQKFTLSVDVEGGRLVLLRRQRDSQEDWTTFTHDRIRQLIKSQRVQNKLGVVFEKEKDRTQRKDFIFVSARKREAFCQLLQLMKNKHSKQDEPDMISVFIGTWNMGSVPPPKNVTSWFTSKGLGKALDEVTVTIPHDIYVFGTQENSVGDREWLDLLRGGLKELTDLDYRPIAMQSLWNIKVAVLVKPEHENRISHVSTSSVKTGIANTLGNKGAVGVSFMFNGTSFGFVNCHLTSGNEKTTRRNQNYLDILRLLSLGDRQLSAFDISLRFTHLFWFGDLNYRLDMDIQEILNYISRREFEPLLRVDQLNLEREKHKVFLRFSEEEISFPPTYRYERGSRDTYAWHKQKPTGVRTNVPSWCDRILWKSYPETHIICNSYGCTDDIVTSDHSPVFGTFEVGVTSQFISKKGLSKTSDQAYIEFESIEAIVKTASRTKFFIEFYSTCLEEYKKSFENDAQSSDNINFLKVQWSSRQLPTLKPILADIEYLQDQHLLLTVKSMDGYESYGECVVALKSMIGSTAQQFLTFLSHRGEETGNIRGSMKVRVPTERLGTRERLYEWISIDKDDTGAKSKAPSVLRGSQEHRSGSRKPTSTEASCPLSKLFEEPEKPPPTGRPPAPPRAVPREESLNPRLKSEGTPEQEGVAAPPPKNSFNNPAYYVLEGVPHQLLPLEPTSFARAPIPPTTKNKVAITVPAPQLGRHRTPRVGEGSSSDEDSGGTLPPPDFPPPPLPDSAIFLPPNLDPLSMPVVRGRSVGEARGPPPPKAHPRPPLPPGTSPASTFLEEVASADDRSCSVLQMAKTLSEVDYSPGPGRSALLPNPLELQLPRGPSDYGRPLSFPPPRIRESIQEDLAEEAPCPQGGRASGLGEAGMGAWLRAIGLERYEEGLVHNGWDDLEFLSDITEEDLEEAGVQDPAHKRLLLDTLQLSK

Target ORF information:

RefSeq Version	NM_022944.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus inositol polyphosphate phosphatase-like 1 (Inppl1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022944.2

ORF Insert Sequence:

ATGGCCTCAG TGTGTGGGGC ACCGAGTCCC GGGGGCGCGC TAGGCAGCCA GGCCCCTGCC 
TGGTATCACC GTGACCTGAG CCGCGCGGCT GCGGAGGAGC TGCTAGCTCG GGCAGGCCGC 
GATGGCAGCT TCCTGGTGCG AGACAGCGAG AGCGTGGCGG GGGCCTTCGC ACTCTGCGTC 
CTGTATCAAA AGCACGTGCA CACCTACCGC ATTCTGCCAG ATGGAGAGGA TTTCCTGGCT 
GTGCAGACCT CACAGGGCGT TCCTGTGCGC CGCTTCCAGA CCCTGGGTGA GCTTATAGGC 
CTGTATGCCC AGCCCAACCA GGGTCTTGTC TGTGCTCTGC TGCTGCCTGT AGAGGGGGAG 
AGAGAGCCAG ATCCACCGGA TGACCGAGAT GCCTCAGATG TGGAGGACGA GAAACCCCCA 
CTACCCCCGC GCTCTGGCTC TACCAGCATT TCTGTCCCTG CGGGGCCTAG CAGCCCCCTG 
CCAGCCCCTG AGACTCCCAC AACTCCAGCA GCTGAGAGCA CTCCTAATGG ACTCAGCACT 
GTGTCACATG AGTATCTGAA GGGCAGCTAC GGGCTGGACC TGGAGGCTGT ACGAGGCGGA 
GCCAGCAACT TGCCCCATCT CACCCGAACC CTTGTCACCT CATGCCGTAG GCTACACAGC 
GAGGTGGACA AGGTCCTGTC AGGCCTAGAG ATCCTGTCGA AGGTGTTTGA CCAGCAGAGC 
TCACCCATGG TGACCCGCCT TTTGCAGCAG CAGAGCCTAC CACAGACTGG AGAGCAAGAG 
TTGGAGAGCC TTGTGCTGAA GCTATCTGTG CTAAAGGACT TCCTGTCAGG CATCCAGAAG 
AAGGCCCTAA AGGCACTGCA GGACATGAGC TCCACAGCAC CTCCGGCTCC ATTGCAGCCC 
TCCATACGAA AGGCCAAGAC CATCCCTGTG CAAGCCTTTG AGGTGAAGCT GGATGTGACA 
CTGGGTGACC TGACCAAGAT CGGGAAGTCC CAGAAGTTCA CACTGAGCGT GGATGTGGAG 
GGTGGGAGGC TGGTACTGCT GAGGAGACAG CGTGACTCCC AGGAGGACTG GACGACCTTC 
ACACACGACC GGATCCGGCA GCTCATTAAA TCCCAGCGTG TGCAGAACAA GCTGGGTGTT 
GTGTTTGAAA AGGAGAAAGA TCGGACGCAG CGCAAGGACT TCATCTTTGT CAGTGCCCGG 
AAGCGAGAAG CCTTCTGCCA GCTTCTGCAG CTCATGAAGA ACAAGCATTC CAAGCAGGAT 
GAACCTGACA TGATCTCCGT CTTCATAGGC ACCTGGAACA TGGGAAGTGT ACCACCACCA 
AAAAACGTGA CATCTTGGTT CACATCAAAG GGACTGGGGA AAGCCCTGGA TGAGGTCACA 
GTGACTATAC CCCACGATAT CTATGTCTTT GGGACTCAGG AGAACTCAGT GGGTGACAGA 
GAGTGGCTGG ATCTGCTGCG TGGGGGCCTC AAGGAGCTTA CAGATCTGGA TTACCGTCCG 
ATTGCTATGC AGTCACTGTG GAACATCAAG GTGGCCGTGC TGGTCAAGCC AGAACATGAG 
AACCGCATCA GCCACGTTAG TACGTCCAGT GTGAAGACTG GTATCGCCAA TACCCTGGGG 
AACAAGGGAG CTGTGGGTGT TTCCTTCATG TTCAATGGCA CTTCTTTTGG CTTCGTGAAT 
TGCCATCTCA CCTCAGGGAA TGAGAAGACT ACTCGGCGGA ACCAGAATTA TCTGGACATC 
CTGCGTCTTC TCTCATTGGG TGATCGGCAG CTCAGTGCCT TTGACATCTC TTTGAGGTTC 
ACTCATCTCT TCTGGTTTGG GGACCTTAAC TACCGCTTAG ACATGGATAT CCAGGAGATC 
CTGAACTACA TTAGTAGGAG AGAGTTTGAG CCCCTGCTCA GGGTGGACCA GCTCAACCTG 
GAGCGGGAGA AGCATAAGGT CTTCCTTCGA TTTAGTGAGG AGGAGATATC TTTCCCACCC 
ACCTACCGCT ACGAGCGGGG TTCCCGAGAC ACATATGCTT GGCACAAGCA GAAGCCAACT 
GGGGTCCGGA CCAATGTGCC TTCATGGTGT GACCGGATTC TATGGAAATC CTATCCTGAA 
ACCCACATCA TCTGCAATTC CTATGGTTGC ACTGATGACA TTGTTACCAG TGACCATTCT 
CCTGTGTTTG GGACATTTGA GGTTGGAGTG ACTTCCCAGT TCATCTCCAA GAAAGGTCTC 
TCTAAGACCT CAGACCAGGC CTACATTGAG TTTGAGAGCA TCGAGGCCAT CGTGAAGACG 
GCCAGCCGCA CCAAGTTCTT CATTGAGTTC TATTCTACCT GCTTGGAAGA GTACAAGAAG 
AGCTTCGAGA ATGACGCTCA GAGCAGTGAC AACATCAATT TCCTCAAGGT GCAGTGGTCC 
TCGCGCCAGC TGCCCACGCT CAAGCCAATT CTGGCTGACA TTGAGTACCT GCAGGATCAG 
CATCTCCTGC TCACAGTCAA GTCCATGGAT GGCTACGAAT CATATGGGGA GTGTGTGGTT 
GCACTCAAAT CCATGATTGG CAGCACGGCC CAGCAGTTCT TGACCTTCTT GTCCCACCGT 
GGAGAGGAGA CAGGCAACAT TCGTGGCTCC ATGAAGGTGC GGGTGCCCAC AGAACGCCTG 
GGCACCCGTG AGCGGCTCTA TGAATGGATT AGCATTGATA AGGATGACAC AGGAGCCAAA 
AGCAAGGCTC CTTCAGTGTT GCGGGGCAGC CAGGAGCACA GATCTGGGAG CCGCAAGCCA 
ACTTCCACAG AGGCCTCCTG TCCACTGTCC AAGTTGTTTG AAGAGCCTGA AAAGCCACCA 
CCGACTGGCA GGCCCCCAGC CCCACCACGG GCAGTTCCTA GGGAGGAGTC CTTGAACCCC 
AGGTTGAAGT CAGAGGGGAC ACCTGAACAG GAAGGAGTAG CAGCCCCTCC ACCCAAGAAC 
AGCTTCAATA ACCCTGCCTA CTACGTCCTT GAAGGGGTCC CACATCAGCT GCTGCCCCTG 
GAGCCAACCT CATTTGCCAG GGCCCCTATC CCACCTACCA CCAAGAACAA AGTGGCCATC 
ACAGTGCCTG CTCCTCAGCT TGGGCGCCAC CGGACCCCTC GTGTGGGGGA GGGAAGCTCT 
TCGGATGAGG ACTCTGGGGG CACACTGCCT CCTCCAGACT TCCCACCTCC ACCACTGCCA 
GACTCAGCCA TCTTCCTGCC CCCTAACCTG GATCCTTTAT CAATGCCAGT GGTCAGGGGC 
CGAAGTGTGG GTGAGGCCCG TGGCCCACCA CCTCCCAAGG CCCATCCAAG ACCACCACTA 
CCGCCGGGCA CCTCACCTGC CAGTACTTTT TTGGAAGAGG TTGCAAGTGC GGATGACCGG 
TCTTGCTCAG TACTGCAGAT GGCCAAGACA CTCAGTGAGG TAGATTATTC TCCTGGGCCT 
GGACGCTCAG CACTCCTCCC CAACCCCTTG GAATTGCAGC TTCCCCGAGG GCCCTCGGAC 
TACGGACGAC CCCTCAGCTT CCCTCCACCC CGCATCCGGG AGAGCATCCA AGAAGACTTG 
GCAGAGGAGG CTCCGTGCCC GCAGGGCGGG CGGGCCAGCG GGCTGGGAGA GGCGGGCATG 
GGTGCCTGGC TGCGGGCCAT CGGCTTGGAG CGCTATGAGG AGGGCCTGGT GCACAATGGC 
TGGGACGACC TGGAGTTTCT CAGTGACATC ACTGAGGAAG ACCTCGAGGA AGCTGGGGTG 
CAGGATCCTG CTCACAAGCG CCTTCTTCTG GACACGCTGC AGCTCAGCAA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Inppl1 ( NM_001270843.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001257772.1 Rattus norvegicus inositol polyphosphate phosphatase-like 1 (Inppl1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	ORa09872
Clone ID Related Accession (Same CDS sequence)	NM_001270843.1
Accession Version	NM_001270843.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3552bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-21
Organism	Rattus norvegicus(Norway rat)
Product	phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AB011439.1, FQ139232.1, CK653108.1, AB025794.1, BQ199460.1 and CA506674.1. Transcript Variant: This variant (2) differs in the 5' UTR and lacks an internal exon in the 3' coding region, compared to variant 1. The resulting isoform (2) is C-terminal truncated, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB011439.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2689594, SAMEA2689596 [ECO:0000350] ##Evidence-Data-END##

ATGGCCTCAG TGTGTGGGGC ACCGAGTCCC GGGGGCGCGC TAGGCAGCCA GGCCCCTGCC 
TGGTATCACC GTGACCTGAG CCGCGCGGCT GCGGAGGAGC TGCTAGCTCG GGCAGGCCGC 
GATGGCAGCT TCCTGGTGCG AGACAGCGAG AGCGTGGCGG GGGCCTTCGC ACTCTGCGTC 
CTGTATCAAA AGCACGTGCA CACCTACCGC ATTCTGCCAG ATGGAGAGGA TTTCCTGGCT 
GTGCAGACCT CACAGGGCGT TCCTGTGCGC CGCTTCCAGA CCCTGGGTGA GCTTATAGGC 
CTGTATGCCC AGCCCAACCA GGGTCTTGTC TGTGCTCTGC TGCTGCCTGT AGAGGGGGAG 
AGAGAGCCAG ATCCACCGGA TGACCGAGAT GCCTCAGATG TGGAGGACGA GAAACCCCCA 
CTACCCCCGC GCTCTGGCTC TACCAGCATT TCTGTCCCTG CGGGGCCTAG CAGCCCCCTG 
CCAGCCCCTG AGACTCCCAC AACTCCAGCA GCTGAGAGCA CTCCTAATGG ACTCAGCACT 
GTGTCACATG AGTATCTGAA GGGCAGCTAC GGGCTGGACC TGGAGGCTGT ACGAGGCGGA 
GCCAGCAACT TGCCCCATCT CACCCGAACC CTTGTCACCT CATGCCGTAG GCTACACAGC 
GAGGTGGACA AGGTCCTGTC AGGCCTAGAG ATCCTGTCGA AGGTGTTTGA CCAGCAGAGC 
TCACCCATGG TGACCCGCCT TTTGCAGCAG CAGAGCCTAC CACAGACTGG AGAGCAAGAG 
TTGGAGAGCC TTGTGCTGAA GCTATCTGTG CTAAAGGACT TCCTGTCAGG CATCCAGAAG 
AAGGCCCTAA AGGCACTGCA GGACATGAGC TCCACAGCAC CTCCGGCTCC ATTGCAGCCC 
TCCATACGAA AGGCCAAGAC CATCCCTGTG CAAGCCTTTG AGGTGAAGCT GGATGTGACA 
CTGGGTGACC TGACCAAGAT CGGGAAGTCC CAGAAGTTCA CACTGAGCGT GGATGTGGAG 
GGTGGGAGGC TGGTACTGCT GAGGAGACAG CGTGACTCCC AGGAGGACTG GACGACCTTC 
ACACACGACC GGATCCGGCA GCTCATTAAA TCCCAGCGTG TGCAGAACAA GCTGGGTGTT 
GTGTTTGAAA AGGAGAAAGA TCGGACGCAG CGCAAGGACT TCATCTTTGT CAGTGCCCGG 
AAGCGAGAAG CCTTCTGCCA GCTTCTGCAG CTCATGAAGA ACAAGCATTC CAAGCAGGAT 
GAACCTGACA TGATCTCCGT CTTCATAGGC ACCTGGAACA TGGGAAGTGT ACCACCACCA 
AAAAACGTGA CATCTTGGTT CACATCAAAG GGACTGGGGA AAGCCCTGGA TGAGGTCACA 
GTGACTATAC CCCACGATAT CTATGTCTTT GGGACTCAGG AGAACTCAGT GGGTGACAGA 
GAGTGGCTGG ATCTGCTGCG TGGGGGCCTC AAGGAGCTTA CAGATCTGGA TTACCGTCCG 
ATTGCTATGC AGTCACTGTG GAACATCAAG GTGGCCGTGC TGGTCAAGCC AGAACATGAG 
AACCGCATCA GCCACGTTAG TACGTCCAGT GTGAAGACTG GTATCGCCAA TACCCTGGGG 
AACAAGGGAG CTGTGGGTGT TTCCTTCATG TTCAATGGCA CTTCTTTTGG CTTCGTGAAT 
TGCCATCTCA CCTCAGGGAA TGAGAAGACT ACTCGGCGGA ACCAGAATTA TCTGGACATC 
CTGCGTCTTC TCTCATTGGG TGATCGGCAG CTCAGTGCCT TTGACATCTC TTTGAGGTTC 
ACTCATCTCT TCTGGTTTGG GGACCTTAAC TACCGCTTAG ACATGGATAT CCAGGAGATC 
CTGAACTACA TTAGTAGGAG AGAGTTTGAG CCCCTGCTCA GGGTGGACCA GCTCAACCTG 
GAGCGGGAGA AGCATAAGGT CTTCCTTCGA TTTAGTGAGG AGGAGATATC TTTCCCACCC 
ACCTACCGCT ACGAGCGGGG TTCCCGAGAC ACATATGCTT GGCACAAGCA GAAGCCAACT 
GGGGTCCGGA CCAATGTGCC TTCATGGTGT GACCGGATTC TATGGAAATC CTATCCTGAA 
ACCCACATCA TCTGCAATTC CTATGGTTGC ACTGATGACA TTGTTACCAG TGACCATTCT 
CCTGTGTTTG GGACATTTGA GGTTGGAGTG ACTTCCCAGT TCATCTCCAA GAAAGGTCTC 
TCTAAGACCT CAGACCAGGC CTACATTGAG TTTGAGAGCA TCGAGGCCAT CGTGAAGACG 
GCCAGCCGCA CCAAGTTCTT CATTGAGTTC TATTCTACCT GCTTGGAAGA GTACAAGAAG 
AGCTTCGAGA ATGACGCTCA GAGCAGTGAC AACATCAATT TCCTCAAGGT GCAGTGGTCC 
TCGCGCCAGC TGCCCACGCT CAAGCCAATT CTGGCTGACA TTGAGTACCT GCAGGATCAG 
CATCTCCTGC TCACAGTCAA GTCCATGGAT GGCTACGAAT CATATGGGGA GTGTGTGGTT 
GCACTCAAAT CCATGATTGG CAGCACGGCC CAGCAGTTCT TGACCTTCTT GTCCCACCGT 
GGAGAGGAGA CAGGCAACAT TCGTGGCTCC ATGAAGGTGC GGGTGCCCAC AGAACGCCTG 
GGCACCCGTG AGCGGCTCTA TGAATGGATT AGCATTGATA AGGATGACAC AGGAGCCAAA 
AGCAAGGCTC CTTCAGTGTT GCGGGGCAGC CAGGAGCACA GATCTGGGAG CCGCAAGCCA 
ACTTCCACAG AGGCCTCCTG TCCACTGTCC AAGTTGTTTG AAGAGCCTGA AAAGCCACCA 
CCGACTGGCA GGCCCCCAGC CCCACCACGG GCAGTTCCTA GGGAGGAGTC CTTGAACCCC 
AGGTTGAAGT CAGAGGGGAC ACCTGAACAG GAAGGAGTAG CAGCCCCTCC ACCCAAGAAC 
AGCTTCAATA ACCCTGCCTA CTACGTCCTT GAAGGGGTCC CACATCAGCT GCTGCCCCTG 
GAGCCAACCT CATTTGCCAG GGCCCCTATC CCACCTACCA CCAAGAACAA AGTGGCCATC 
ACAGTGCCTG CTCCTCAGCT TGGGCGCCAC CGGACCCCTC GTGTGGGGGA GGGAAGCTCT 
TCGGATGAGG ACTCTGGGGG CACACTGCCT CCTCCAGACT TCCCACCTCC ACCACTGCCA 
GACTCAGCCA TCTTCCTGCC CCCTAACCTG GATCCTTTAT CAATGCCAGT GGTCAGGGGC 
CGAAGTGTGG GTGAGGCCCG TGGCCCACCA CCTCCCAAGG CCCATCCAAG ACCACCACTA 
CCGCCGGGCA CCTCACCTGC CAGTACTTTT TTGGAAGAGG TTGCAAGTGC GGATGACCGG 
TCTTGCTCAG TACTGCAGAT GGCCAAGACA CTCAGTGAGG TAGATTATTC TCCTGGGCCT 
GGACGCTCAG CACTCCTCCC CAACCCCTTG GAATTGCAGC TTCCCCGAGG GCCCTCGGAC 
TACGGACGAC CCCTCAGCTT CCCTCCACCC CGCATCCGGG AGAGCATCCA AGAAGACTTG 
GCAGAGGAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001257772.1
CDS	232..3783
Translation	MASVCGAPSPGGALGSQAPAWYHRDLSRAAAEELLARAGRDGSFLVRDSESVAGAFALCVLYQKHVHTYRILPDGEDFLAVQTSQGVPVRRFQTLGELIGLYAQPNQGLVCALLLPVEGEREPDPPDDRDASDVEDEKPPLPPRSGSTSISVPAGPSSPLPAPETPTTPAAESTPNGLSTVSHEYLKGSYGLDLEAVRGGASNLPHLTRTLVTSCRRLHSEVDKVLSGLEILSKVFDQQSSPMVTRLLQQQSLPQTGEQELESLVLKLSVLKDFLSGIQKKALKALQDMSSTAPPAPLQPSIRKAKTIPVQAFEVKLDVTLGDLTKIGKSQKFTLSVDVEGGRLVLLRRQRDSQEDWTTFTHDRIRQLIKSQRVQNKLGVVFEKEKDRTQRKDFIFVSARKREAFCQLLQLMKNKHSKQDEPDMISVFIGTWNMGSVPPPKNVTSWFTSKGLGKALDEVTVTIPHDIYVFGTQENSVGDREWLDLLRGGLKELTDLDYRPIAMQSLWNIKVAVLVKPEHENRISHVSTSSVKTGIANTLGNKGAVGVSFMFNGTSFGFVNCHLTSGNEKTTRRNQNYLDILRLLSLGDRQLSAFDISLRFTHLFWFGDLNYRLDMDIQEILNYISRREFEPLLRVDQLNLEREKHKVFLRFSEEEISFPPTYRYERGSRDTYAWHKQKPTGVRTNVPSWCDRILWKSYPETHIICNSYGCTDDIVTSDHSPVFGTFEVGVTSQFISKKGLSKTSDQAYIEFESIEAIVKTASRTKFFIEFYSTCLEEYKKSFENDAQSSDNINFLKVQWSSRQLPTLKPILADIEYLQDQHLLLTVKSMDGYESYGECVVALKSMIGSTAQQFLTFLSHRGEETGNIRGSMKVRVPTERLGTRERLYEWISIDKDDTGAKSKAPSVLRGSQEHRSGSRKPTSTEASCPLSKLFEEPEKPPPTGRPPAPPRAVPREESLNPRLKSEGTPEQEGVAAPPPKNSFNNPAYYVLEGVPHQLLPLEPTSFARAPIPPTTKNKVAITVPAPQLGRHRTPRVGEGSSSDEDSGGTLPPPDFPPPPLPDSAIFLPPNLDPLSMPVVRGRSVGEARGPPPPKAHPRPPLPPGTSPASTFLEEVASADDRSCSVLQMAKTLSEVDYSPGPGRSALLPNPLELQLPRGPSDYGRPLSFPPPRIRESIQEDLAEE

Target ORF information:

RefSeq Version	NM_001270843.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus inositol polyphosphate phosphatase-like 1 (Inppl1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001270843.1

ORF Insert Sequence:

ATGGCCTCAG TGTGTGGGGC ACCGAGTCCC GGGGGCGCGC TAGGCAGCCA GGCCCCTGCC 
TGGTATCACC GTGACCTGAG CCGCGCGGCT GCGGAGGAGC TGCTAGCTCG GGCAGGCCGC 
GATGGCAGCT TCCTGGTGCG AGACAGCGAG AGCGTGGCGG GGGCCTTCGC ACTCTGCGTC 
CTGTATCAAA AGCACGTGCA CACCTACCGC ATTCTGCCAG ATGGAGAGGA TTTCCTGGCT 
GTGCAGACCT CACAGGGCGT TCCTGTGCGC CGCTTCCAGA CCCTGGGTGA GCTTATAGGC 
CTGTATGCCC AGCCCAACCA GGGTCTTGTC TGTGCTCTGC TGCTGCCTGT AGAGGGGGAG 
AGAGAGCCAG ATCCACCGGA TGACCGAGAT GCCTCAGATG TGGAGGACGA GAAACCCCCA 
CTACCCCCGC GCTCTGGCTC TACCAGCATT TCTGTCCCTG CGGGGCCTAG CAGCCCCCTG 
CCAGCCCCTG AGACTCCCAC AACTCCAGCA GCTGAGAGCA CTCCTAATGG ACTCAGCACT 
GTGTCACATG AGTATCTGAA GGGCAGCTAC GGGCTGGACC TGGAGGCTGT ACGAGGCGGA 
GCCAGCAACT TGCCCCATCT CACCCGAACC CTTGTCACCT CATGCCGTAG GCTACACAGC 
GAGGTGGACA AGGTCCTGTC AGGCCTAGAG ATCCTGTCGA AGGTGTTTGA CCAGCAGAGC 
TCACCCATGG TGACCCGCCT TTTGCAGCAG CAGAGCCTAC CACAGACTGG AGAGCAAGAG 
TTGGAGAGCC TTGTGCTGAA GCTATCTGTG CTAAAGGACT TCCTGTCAGG CATCCAGAAG 
AAGGCCCTAA AGGCACTGCA GGACATGAGC TCCACAGCAC CTCCGGCTCC ATTGCAGCCC 
TCCATACGAA AGGCCAAGAC CATCCCTGTG CAAGCCTTTG AGGTGAAGCT GGATGTGACA 
CTGGGTGACC TGACCAAGAT CGGGAAGTCC CAGAAGTTCA CACTGAGCGT GGATGTGGAG 
GGTGGGAGGC TGGTACTGCT GAGGAGACAG CGTGACTCCC AGGAGGACTG GACGACCTTC 
ACACACGACC GGATCCGGCA GCTCATTAAA TCCCAGCGTG TGCAGAACAA GCTGGGTGTT 
GTGTTTGAAA AGGAGAAAGA TCGGACGCAG CGCAAGGACT TCATCTTTGT CAGTGCCCGG 
AAGCGAGAAG CCTTCTGCCA GCTTCTGCAG CTCATGAAGA ACAAGCATTC CAAGCAGGAT 
GAACCTGACA TGATCTCCGT CTTCATAGGC ACCTGGAACA TGGGAAGTGT ACCACCACCA 
AAAAACGTGA CATCTTGGTT CACATCAAAG GGACTGGGGA AAGCCCTGGA TGAGGTCACA 
GTGACTATAC CCCACGATAT CTATGTCTTT GGGACTCAGG AGAACTCAGT GGGTGACAGA 
GAGTGGCTGG ATCTGCTGCG TGGGGGCCTC AAGGAGCTTA CAGATCTGGA TTACCGTCCG 
ATTGCTATGC AGTCACTGTG GAACATCAAG GTGGCCGTGC TGGTCAAGCC AGAACATGAG 
AACCGCATCA GCCACGTTAG TACGTCCAGT GTGAAGACTG GTATCGCCAA TACCCTGGGG 
AACAAGGGAG CTGTGGGTGT TTCCTTCATG TTCAATGGCA CTTCTTTTGG CTTCGTGAAT 
TGCCATCTCA CCTCAGGGAA TGAGAAGACT ACTCGGCGGA ACCAGAATTA TCTGGACATC 
CTGCGTCTTC TCTCATTGGG TGATCGGCAG CTCAGTGCCT TTGACATCTC TTTGAGGTTC 
ACTCATCTCT TCTGGTTTGG GGACCTTAAC TACCGCTTAG ACATGGATAT CCAGGAGATC 
CTGAACTACA TTAGTAGGAG AGAGTTTGAG CCCCTGCTCA GGGTGGACCA GCTCAACCTG 
GAGCGGGAGA AGCATAAGGT CTTCCTTCGA TTTAGTGAGG AGGAGATATC TTTCCCACCC 
ACCTACCGCT ACGAGCGGGG TTCCCGAGAC ACATATGCTT GGCACAAGCA GAAGCCAACT 
GGGGTCCGGA CCAATGTGCC TTCATGGTGT GACCGGATTC TATGGAAATC CTATCCTGAA 
ACCCACATCA TCTGCAATTC CTATGGTTGC ACTGATGACA TTGTTACCAG TGACCATTCT 
CCTGTGTTTG GGACATTTGA GGTTGGAGTG ACTTCCCAGT TCATCTCCAA GAAAGGTCTC 
TCTAAGACCT CAGACCAGGC CTACATTGAG TTTGAGAGCA TCGAGGCCAT CGTGAAGACG 
GCCAGCCGCA CCAAGTTCTT CATTGAGTTC TATTCTACCT GCTTGGAAGA GTACAAGAAG 
AGCTTCGAGA ATGACGCTCA GAGCAGTGAC AACATCAATT TCCTCAAGGT GCAGTGGTCC 
TCGCGCCAGC TGCCCACGCT CAAGCCAATT CTGGCTGACA TTGAGTACCT GCAGGATCAG 
CATCTCCTGC TCACAGTCAA GTCCATGGAT GGCTACGAAT CATATGGGGA GTGTGTGGTT 
GCACTCAAAT CCATGATTGG CAGCACGGCC CAGCAGTTCT TGACCTTCTT GTCCCACCGT 
GGAGAGGAGA CAGGCAACAT TCGTGGCTCC ATGAAGGTGC GGGTGCCCAC AGAACGCCTG 
GGCACCCGTG AGCGGCTCTA TGAATGGATT AGCATTGATA AGGATGACAC AGGAGCCAAA 
AGCAAGGCTC CTTCAGTGTT GCGGGGCAGC CAGGAGCACA GATCTGGGAG CCGCAAGCCA 
ACTTCCACAG AGGCCTCCTG TCCACTGTCC AAGTTGTTTG AAGAGCCTGA AAAGCCACCA 
CCGACTGGCA GGCCCCCAGC CCCACCACGG GCAGTTCCTA GGGAGGAGTC CTTGAACCCC 
AGGTTGAAGT CAGAGGGGAC ACCTGAACAG GAAGGAGTAG CAGCCCCTCC ACCCAAGAAC 
AGCTTCAATA ACCCTGCCTA CTACGTCCTT GAAGGGGTCC CACATCAGCT GCTGCCCCTG 
GAGCCAACCT CATTTGCCAG GGCCCCTATC CCACCTACCA CCAAGAACAA AGTGGCCATC 
ACAGTGCCTG CTCCTCAGCT TGGGCGCCAC CGGACCCCTC GTGTGGGGGA GGGAAGCTCT 
TCGGATGAGG ACTCTGGGGG CACACTGCCT CCTCCAGACT TCCCACCTCC ACCACTGCCA 
GACTCAGCCA TCTTCCTGCC CCCTAACCTG GATCCTTTAT CAATGCCAGT GGTCAGGGGC 
CGAAGTGTGG GTGAGGCCCG TGGCCCACCA CCTCCCAAGG CCCATCCAAG ACCACCACTA 
CCGCCGGGCA CCTCACCTGC CAGTACTTTT TTGGAAGAGG TTGCAAGTGC GGATGACCGG 
TCTTGCTCAG TACTGCAGAT GGCCAAGACA CTCAGTGAGG TAGATTATTC TCCTGGGCCT 
GGACGCTCAG CACTCCTCCC CAACCCCTTG GAATTGCAGC TTCCCCGAGG GCCCTCGGAC 
TACGGACGAC CCCTCAGCTT CCCTCCACCC CGCATCCGGG AGAGCATCCA AGAAGACTTG 
GCAGAGGAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Exome sequencing identifies INPPL1 mutations as a cause of opsismodysplasia.
American journal of human genetics92(1)144-9(2013 Jan)
Huber C,Faqeih EA,Bartholdi D,Bole-Feysot C,Borochowitz Z,Cavalcanti DP,Frigo A,Nitschke P,Roume J,Santos HG,Shalev SA,Superti-Furga A,Delezoide AL,Le Merrer M,Munnich A,Cormier-Daire V

Regulation of insulin signaling and glucose transporter 4 (GLUT4) exocytosis by phosphatidylinositol 3,4,5-trisphosphate (PIP3) phosphatase, skeletal muscle, and kidney enriched inositol polyphosphate phosphatase (SKIP).
The Journal of biological chemistry287(10)6991-9(2012 Mar)
Ijuin T,Takenawa T

SH3YL1 regulates dorsal ruffle formation by a novel phosphoinositide-binding domain.
The Journal of cell biology193(5)901-16(2011 May)
Hasegawa J,Tokuda E,Tenno T,Tsujita K,Sawai H,Hiroaki H,Takenawa T,Itoh T

Serum withdrawal-induced accumulation of phosphoinositide 3-kinase lipids in differentiating 3T3-L6 myoblasts: distinct roles for Ship2 and PTEN.
Molecular and cellular biology27(23)8098-112(2007 Dec)
Mandl A,Sarkes D,Carricaburu V,Jung V,Rameh L

An essential role for the SHIP2-dependent negative feedback loop in neuritogenesis of nerve growth factor-stimulated PC12 cells.
The Journal of cell biology177(5)817-27(2007 Jun)
Aoki K,Nakamura T,Inoue T,Meyer T,Matsuda M

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Inppl1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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