Snap23 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Snap23
Entrez Gene ID	64630
Full Name	synaptosome associated protein 23
General protein information	Preferred Names synaptosome associated protein 23 Names synaptosomal-associated protein 23 SNAP-23 synaptosomal-associated protein, 23 kD vesicle-membrane fusion protein SNAP-23
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 3 Map Location: 3q35
Summary	participates in the formation of 20S SNARE complexes along with syntaxin 4 and VAMP2/3 [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_022689.2	NP_073180.1	synaptosomal-associated protein 23

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	SNAP23	XP_001154600.1
Mus musculus (house mouse)	Snap23	NP_001171263.1
Gallus gallus (chicken)	SNAP23	NP_001186595.1
Xenopus tropicalis (tropical clawed frog)	snap23	NP_001107340.1
Homo sapiens (human)	SNAP23	NP_003816.2
	SNAP23	XP_002804784.1
Canis lupus familiaris (dog)	SNAP23	XP_535442.1
Bos taurus (cattle)	SNAP23	NP_001069299.1
Rattus norvegicus (Norway rat)	Snap23	NP_073180.1
Danio rerio (zebrafish)	zgc:56072	NP_956484.1

Gene Ontology
Bibliography

Related articles in PubMed

Syntaxin-4 and SNAP23 act as exocytic SNAREs to release NGF from cultured Schwann cells.
Lin M, Jiang M, Ding F, Cao Z
Neuroscience letters65397-104(2017 Jul)

Electrostatic anchoring precedes stable membrane attachment of SNAP25/SNAP23 to the plasma membrane.
Weber P, Batoulis H, Rink KM, Dahlhoff S, Pinkwart K, S?llner TH, Lang T
eLife6(2017 02)

Differential vesicular sorting of AMPA and GABAA receptors.
Gu Y, Chiu SL, Liu B, Wu PH, Delannoy M, Lin DT, Wirtz D, Huganir RL
Proceedings of the National Academy of Sciences of the United States of America113(7)E922-31(2016 Feb)

Diminished Lipid Raft SNAP23 Increases Blood Pressure by Inhibiting the Membrane Fluidity of Vascular Smooth-Muscle Cells.
Yoon MS, Won KJ, Kim DY, Hwang DI, Yoon SW, Jung SH, Lee KP, Jung D, Choi WS, Kim B, Lee HM
Journal of vascular research52(5)321-33(2015)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Electrostatic anchoring precedes stable membrane attachment of SNAP25 and SNAP23 to the plasma membrane.
Title: Electrostatic anchoring precedes stable membrane attachment of SNAP25/SNAP23 to the plasma membrane.

Low expression of SNAP23 in lipid rafts of vascular smooth muscle cells might be a potential cause for hypertension in spontaneously hypertensive rats.
Title: Diminished Lipid Raft SNAP23 Increases Blood Pressure by Inhibiting the Membrane Fluidity of Vascular Smooth-Muscle Cells.

SNAP23-VAMP2 interaction plays a key role in cAMP-mediated exocytosis from parotid glands.
Title: Isoproterenol stimulates transient SNAP23-VAMP2 interaction in rat parotid glands.

Annexin A7 may function in co-ordination with SNARE proteins and that protein kinase activation may be required for annexin A7 trafficking.
Title: Annexin A7 and SNAP23 interactions in alveolar type II cells and in vitro: a role for Ca(2+) and PKC.

SNAP23 and SNAP25 palmitoylation is regulated by DHHC palmitoyl transferases
Title: Palmitoylation of the SNAP25 protein family: specificity and regulation by DHHC palmitoyl transferases.

The following Snap23 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Snap23 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa06259	NM_022689.2 Latest version!	Rattus norvegicus synaptosome associated protein 23 (Snap23), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Snap23 ( NM_022689.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_073180.1 Rattus norvegicus synaptosome associated protein 23 (Snap23), mRNA.

Price & Availability↑

CloneID	ORa06259
Clone ID Related Accession (Same CDS sequence)	NM_022689.2
Accession Version	NM_022689.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 633bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-23
Organism	Rattus norvegicus(Norway rat)
Product	synaptosomal-associated protein 23
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC127494.1. On Nov 13, 2006 this sequence version replaced NM_022689.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC127494.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGATGATC TATCACCAGA AGAAATTCAG CTTCGGGCTC ACCAAGTTAC TGATGAGTCT 
CTGGAAAGCA CAAGGAGAAT CCTGGGTTTA GCCATTGAGT CTCAGGATGC AGGAATCAAG 
ACTATCACTA TGCTGGATGA GCAAGGGGAA CAACTAAATC GCATAGAAGA AGGCATGGAC 
CAAATAAATA AAGACATGAG AGAGGCAGAG AAGACTTTAA CAGAACTCAA CAAGTGTTGT 
GGCCTCTGCG TCTGCCCTTG TAATAGGACC AAGAACTTTG AGTCTGGAAA GAACTATAAG 
GCAACATGGG GTGATGGTGG AGACAGCTCA CCTAGCAATG TGGTATCTAA GCAACCAAGC 
CGGATAACAA ATGGTCAGCC TCAGCAGACT ACAGGAGCGG CCAGCGGTGG ATACATTAAA 
CGCATAACTA ATGATGCCAG AGAAGATGAG ATGGAAGAGA ACCTGACTCA AGTGGGCAGC 
ATCCTAGGGA ACCTAAAGAA CATGGCTCTG GATATGGGCA ATGAAATTGA TGCTCAAAAC 
CAGCAAATAC AGAAGATCAC AGAAAAGGCT GACACCAACA AGAATCGCAT TGACATTGCC 
AATACAAGAG CAAAGAAACT CATTGACAGC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_073180.1
CDS	149..781
Translation	MDDLSPEEIQLRAHQVTDESLESTRRILGLAIESQDAGIKTITMLDEQGEQLNRIEEGMDQINKDMREAEKTLTELNKCCGLCVCPCNRTKNFESGKNYKATWGDGGDSSPSNVVSKQPSRITNGQPQQTTGAASGGYIKRITNDAREDEMEENLTQVGSILGNLKNMALDMGNEIDAQNQQIQKITEKADTNKNRIDIANTRAKKLIDS

Target ORF information:

RefSeq Version	NM_022689.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus synaptosome associated protein 23 (Snap23), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022689.2

ORF Insert Sequence:

ATGGATGATC TATCACCAGA AGAAATTCAG CTTCGGGCTC ACCAAGTTAC TGATGAGTCT 
CTGGAAAGCA CAAGGAGAAT CCTGGGTTTA GCCATTGAGT CTCAGGATGC AGGAATCAAG 
ACTATCACTA TGCTGGATGA GCAAGGGGAA CAACTAAATC GCATAGAAGA AGGCATGGAC 
CAAATAAATA AAGACATGAG AGAGGCAGAG AAGACTTTAA CAGAACTCAA CAAGTGTTGT 
GGCCTCTGCG TCTGCCCTTG TAATAGGACC AAGAACTTTG AGTCTGGAAA GAACTATAAG 
GCAACATGGG GTGATGGTGG AGACAGCTCA CCTAGCAATG TGGTATCTAA GCAACCAAGC 
CGGATAACAA ATGGTCAGCC TCAGCAGACT ACAGGAGCGG CCAGCGGTGG ATACATTAAA 
CGCATAACTA ATGATGCCAG AGAAGATGAG ATGGAAGAGA ACCTGACTCA AGTGGGCAGC 
ATCCTAGGGA ACCTAAAGAA CATGGCTCTG GATATGGGCA ATGAAATTGA TGCTCAAAAC 
CAGCAAATAC AGAAGATCAC AGAAAAGGCT GACACCAACA AGAATCGCAT TGACATTGCC 
AATACAAGAG CAAAGAAACT CATTGACAGC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Syntaxin-4 and SNAP23 act as exocytic SNAREs to release NGF from cultured Schwann cells.
Neuroscience letters65397-104(2017 Jul)
Lin M,Jiang M,Ding F,Cao Z

Electrostatic anchoring precedes stable membrane attachment of SNAP25/SNAP23 to the plasma membrane.
eLife6(2017 02)
Weber P,Batoulis H,Rink KM,Dahlhoff S,Pinkwart K,S?llner TH,Lang T

Differential vesicular sorting of AMPA and GABAA receptors.
Proceedings of the National Academy of Sciences of the United States of America113(7)E922-31(2016 Feb)
Gu Y,Chiu SL,Liu B,Wu PH,Delannoy M,Lin DT,Wirtz D,Huganir RL

Diminished Lipid Raft SNAP23 Increases Blood Pressure by Inhibiting the Membrane Fluidity of Vascular Smooth-Muscle Cells.
Journal of vascular research52(5)321-33(2015)
Yoon MS,Won KJ,Kim DY,Hwang DI,Yoon SW,Jung SH,Lee KP,Jung D,Choi WS,Kim B,Lee HM

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Snap23 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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