Tmprss11d cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Tmprss11d
Entrez Gene ID	64565
Full Name	transmembrane protease, serine 11d
Synonyms	Asp
General protein information	Preferred Names transmembrane protease, serine 11d Names transmembrane protease serine 11D AT adrenal secretory serine protease airway trypsin-like protease transmembrane serine protease 11D
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 14 Map Location: 14p21

mRNA and Protein(s)

mRNA	Protein	Name
NM_022630.1	NP_072152.1	transmembrane protease serine 11D isoform b precursor
NM_001033652.1	NP_001028824.1	transmembrane protease serine 11D isoform a

Pathways from BioSystems

Homologies

Homo sapiens (human)	TMPRSS11D	NP_004253.1
	TMPRSS11D	XP_001109114.1
Canis lupus familiaris (dog)	TMPRSS11D	XP_854470.1
Bos taurus (cattle)	TMPRSS11D	XP_002688359.1
Rattus norvegicus (Norway rat)	Tmprss11d	NP_001028824.1
Anopheles gambiae (African malaria mosquito)	TRY1_ANOGA	XP_317170.2
Anopheles gambiae (African malaria mosquito)	TRY4_ANOGA	XP_317173.2
Pan troglodytes (chimpanzee)	TMPRSS11D	XP_526607.2
Anopheles gambiae (African malaria mosquito)	TRY6_ANOGA	XP_317175.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP012842	XP_001230353.1
Anopheles gambiae (African malaria mosquito)	TRY7_ANOGA	XP_317172.2
Mus musculus (house mouse)	Tmprss11d	NP_663536.1
Anopheles gambiae (African malaria mosquito)	TRY5_ANOGA	XP_317174.2
Anopheles gambiae (African malaria mosquito)	TRY3_ANOGA	XP_317171.2
Anopheles gambiae (African malaria mosquito)	TRY2_ANOGA	XP_555167.1

Gene Ontology
Bibliography

Related articles in PubMed

TMPRSS2 and ADAM17 cleave ACE2 differentially and only proteolysis by TMPRSS2 augments entry driven by the severe acute respiratory syndrome coronavirus spike protein.
Heurich A, Hofmann-Winkler H, Gierer S, Liepold T, Jahn O, P?hlmann S
Journal of virology88(2)1293-307(2014 Jan)

Large-scale proteomics and phosphoproteomics of urinary exosomes.
Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal of the American Society of Nephrology : JASN20(2)363-79(2009 Feb)

The adrenal secretory serine protease AsP is a short secretory isoform of the transmembrane airway trypsin-like protease.
Hansen IA, Fassnacht M, Hahner S, Hammer F, Schammann M, Meyer SR, Bicknell AB, Allolio B
Endocrinology145(4)1898-905(2004 Apr)

Identification of a serine protease involved with the regulation of adrenal growth.
Bicknell AB
Annals of the New York Academy of Sciences994118-22(2003 Jun)

Characterization of a serine protease that cleaves pro-gamma-melanotropin at the adrenal to stimulate growth.
Bicknell AB, Lomthaisong K, Woods RJ, Hutchinson EG, Bennett HP, Gladwell RT, Lowry PJ
Cell105(7)903-12(2001 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Predominantly expressed in upper gastrointestinal and respiratory tract-but also in adrenal gland. Complex expression pattern. Multifunctional role beyond adrenal proliferation.
Title: The adrenal secretory serine protease AsP is a short secretory isoform of the transmembrane airway trypsin-like protease.

Results identify a secreted serine protease (adrenal secretory protease) expressed by the adrenal gland, which plays a role in adrenal growth.
Title: Identification of a serine protease involved with the regulation of adrenal growth.

The following Tmprss11d gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Tmprss11d cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa06177	NM_022630.1 Latest version!	Rattus norvegicus transmembrane serine protease 11D (Tmprss11d), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
ORa08504	NM_001033652.1 Latest version!	Rattus norvegicus transmembrane serine protease 11D (Tmprss11d), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Tmprss11d ( NM_022630.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_072152.1 Rattus norvegicus transmembrane serine protease 11D (Tmprss11d), transcript variant 2, mRNA.

Price & Availability↑

CloneID	ORa06177
Clone ID Related Accession (Same CDS sequence)	NM_022630.1
Accession Version	NM_022630.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 840bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-23
Organism	Rattus norvegicus(Norway rat)
Product	transmembrane protease serine 11D isoform b precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF198087.1. ##Evidence-Data-START## Transcript exon combination :: AF198087.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN02642851, SAMN02642852 [ECO:0000348] ##Evidence-Data-END##

ATGAGTTTCA GCTTCTGTTT TGTTGATCTT CTTCTCGTGC TTTCTTTCTT AACGCTAGCA 
CTCACTGACC AGGATACAGA AAATGTTTTG ACTCAAGAAT GTGGAGCACG TCCAGACCTT 
ATAACACTGT CAGAAGAGAG AATCATTGGA GGCACTCAAG CTGAGACAGG TGACTGGCCC 
TGGCAAGTCA GTCTACAGCT CAACAATGTC CACCACTGTG GAGGTACCCT GATCAGTAAC 
TTGTGGGTCC TGACAGCCGC TCACTGCTTC AGAAGCTACT CGAATCCTCA ACAATGGACA 
GCCACCTTTG GTGTTTCTAC AATAAGTCCT AGGTTAAGAG TGAGAGTAAG GGCTATTTTA 
GCCCATGCTG AGTACAACTC CATAACTCGT GATAATGATA TTGCAGTTGT ACAACTTGAC 
AGACCTGTCA CCTTTACCAG AAATATCCAT AGGGTATGTC TCCCAGCAGC AACCCAAAAT 
ATCATACCTG ATTCCGTCGC ATATGCCACA GGATGGGGAT CTCTCACTTA TGGAGGCAAC 
ACGGTCACAA ATCTACAGCA AGGAGAGGTC AGAATAGTAA GTTCGGAGGT GTGCAACGAG 
CCAGCTGGCT ACGGTGGGAG TGTCTTGCCA GGAATGCTCT GTGCTGGAGT CCGTTCAGGG 
GCCGTGGATG CATGCCAGGG TGATTCTGGT GGCCCACTAG TACAAGAAGA CACAAGGCGG 
CTTTGGTTTG TCGTGGGGAT TGTGAGCTGG GGATATCAAT GTGGCCTGCC AAATAAGCCA 
GGAGTGTATA CGCGAGTGAC AGCCTACCGC AACTGGATTA GGCAGCAGAC TGGAATCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_072152.1
CDS	32..871
Translation	MSFSFCFVDLLLVLSFLTLALTDQDTENVLTQECGARPDLITLSEERIIGGTQAETGDWPWQVSLQLNNVHHCGGTLISNLWVLTAAHCFRSYSNPQQWTATFGVSTISPRLRVRVRAILAHAEYNSITRDNDIAVVQLDRPVTFTRNIHRVCLPAATQNIIPDSVAYATGWGSLTYGGNTVTNLQQGEVRIVSSEVCNEPAGYGGSVLPGMLCAGVRSGAVDACQGDSGGPLVQEDTRRLWFVVGIVSWGYQCGLPNKPGVYTRVTAYRNWIRQQTGI

Target ORF information:

RefSeq Version	NM_022630.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus transmembrane serine protease 11D (Tmprss11d), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022630.1

ORF Insert Sequence:

ATGAGTTTCA GCTTCTGTTT TGTTGATCTT CTTCTCGTGC TTTCTTTCTT AACGCTAGCA 
CTCACTGACC AGGATACAGA AAATGTTTTG ACTCAAGAAT GTGGAGCACG TCCAGACCTT 
ATAACACTGT CAGAAGAGAG AATCATTGGA GGCACTCAAG CTGAGACAGG TGACTGGCCC 
TGGCAAGTCA GTCTACAGCT CAACAATGTC CACCACTGTG GAGGTACCCT GATCAGTAAC 
TTGTGGGTCC TGACAGCCGC TCACTGCTTC AGAAGCTACT CGAATCCTCA ACAATGGACA 
GCCACCTTTG GTGTTTCTAC AATAAGTCCT AGGTTAAGAG TGAGAGTAAG GGCTATTTTA 
GCCCATGCTG AGTACAACTC CATAACTCGT GATAATGATA TTGCAGTTGT ACAACTTGAC 
AGACCTGTCA CCTTTACCAG AAATATCCAT AGGGTATGTC TCCCAGCAGC AACCCAAAAT 
ATCATACCTG ATTCCGTCGC ATATGCCACA GGATGGGGAT CTCTCACTTA TGGAGGCAAC 
ACGGTCACAA ATCTACAGCA AGGAGAGGTC AGAATAGTAA GTTCGGAGGT GTGCAACGAG 
CCAGCTGGCT ACGGTGGGAG TGTCTTGCCA GGAATGCTCT GTGCTGGAGT CCGTTCAGGG 
GCCGTGGATG CATGCCAGGG TGATTCTGGT GGCCCACTAG TACAAGAAGA CACAAGGCGG 
CTTTGGTTTG TCGTGGGGAT TGTGAGCTGG GGATATCAAT GTGGCCTGCC AAATAAGCCA 
GGAGTGTATA CGCGAGTGAC AGCCTACCGC AACTGGATTA GGCAGCAGAC TGGAATCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Tmprss11d ( NM_001033652.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001028824.1 Rattus norvegicus transmembrane serine protease 11D (Tmprss11d), transcript variant 1, mRNA.

Price & Availability↑

CloneID	ORa08504
Clone ID Related Accession (Same CDS sequence)	NM_001033652.1
Accession Version	NM_001033652.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1254bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-22
Organism	Rattus norvegicus(Norway rat)
Product	transmembrane protease serine 11D isoform a
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF453776.1. ##Evidence-Data-START## Transcript exon combination :: AF453776.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMEA2689596 [ECO:0000350] ##Evidence-Data-END##

ATGTATAGGC CAAGATCAAT GGTATCACCT TCAAGATTCT TCAATCCCTT TATGGTAGCT 
CTCATTGTCA TAATAACAGT AGGGCTCCTG GCCATGACCG CAGGTCTACT TATTCACTTT 
TTAGCTTTTG ACAAGAGAGC TTACTTTTAT CATAGCAACT TTCATATCCT AAATGTTGAC 
TATACTGAAG CTTTAAACTC ACCAGCTACG CATGAATACA GAACCTTGAG TGAAAGAATC 
GAGTCTATGA TTACTGATGC ATTTCGAGAA TCAAATCTAC GAAGTGAGTT TATCAGGACA 
CATGTTGTCA AACTGAGAAA AGAAGGGAGT GGTGTGGTTG CGGATGTTGT CATGAAATTT 
CGATCTAGTA AGCGTAACAA CAAAAAGGCA ATCAAAACCA GAATCCAATC TGTGCTACAA 
AGACTCAGCA GCTCTGGGAA CTTGGAAATA GCCCCTTCGA ATGGGATAAC ATCACTCACT 
GACCAGGATA CAGAAAATGT TTTGACTCAA GAATGTGGAG CACGTCCAGA CCTTATAACA 
CTGTCAGAAG AGAGAATCAT TGGAGGCACT CAAGCTGAGA CAGGTGACTG GCCCTGGCAA 
GTCAGTCTAC AGCTCAACAA TGTCCACCAC TGTGGAGGTA CCCTGATCAG TAACTTGTGG 
GTCCTGACAG CCGCTCACTG CTTCAGAAGC TACTCGAATC CTCAACAATG GACAGCCACC 
TTTGGTGTTT CTACAATAAG TCCTAGGTTA AGAGTGAGAG TAAGGGCTAT TTTAGCCCAT 
GCTGAGTACA ACTCCATAAC TCGTGATAAT GATATTGCAG TTGTACAACT TGACAGACCT 
GTCACCTTTA CCAGAAATAT CCATAGGGTA TGTCTCCCAG CAGCAACCCA AAATATCATG 
CCTGATTCCG TCGCATATGT CACAGGATGG GGATCTCTCA CTTATGGAGG CAACACGGTC 
ACAAATCTAC AGCAAGGAGA GGTCAGAATA GTAAGTTCGG AGGTGTGCAA CGAGCCAGCT 
GGCTACGGTG GGAGTGTCTT GCCAGGAATG CTCTGTGCTG GAGTCCGTTC AGGGGCCGTG 
GATGCATGCC AGGGTGATTC TGGTGGCCCA CTAGTACAAG AAGACACAAG GCGGCTTTGG 
TTTGTCGTGG GGATTGTGAG CTGGGGATAT CAATGTGGCC TGCCAAATAA GCCAGGAGTG 
TATACGCGAG TGACAGCCTA CCGCAACTGG ATTAGGCAGC AGACTGGAAT CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001028824.1
CDS	247..1500
Translation	MYRPRSMVSPSRFFNPFMVALIVIITVGLLAMTAGLLIHFLAFDKRAYFYHSNFHILNVDYTEALNSPATHEYRTLSERIESMITDAFRESNLRSEFIRTHVVKLRKEGSGVVADVVMKFRSSKRNNKKAIKTRIQSVLQRLSSSGNLEIAPSNGITSLTDQDTENVLTQECGARPDLITLSEERIIGGTQAETGDWPWQVSLQLNNVHHCGGTLISNLWVLTAAHCFRSYSNPQQWTATFGVSTISPRLRVRVRAILAHAEYNSITRDNDIAVVQLDRPVTFTRNIHRVCLPAATQNIMPDSVAYVTGWGSLTYGGNTVTNLQQGEVRIVSSEVCNEPAGYGGSVLPGMLCAGVRSGAVDACQGDSGGPLVQEDTRRLWFVVGIVSWGYQCGLPNKPGVYTRVTAYRNWIRQQTGI

Target ORF information:

RefSeq Version	NM_001033652.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus transmembrane serine protease 11D (Tmprss11d), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001033652.1

ORF Insert Sequence:

ATGTATAGGC CAAGATCAAT GGTATCACCT TCAAGATTCT TCAATCCCTT TATGGTAGCT 
CTCATTGTCA TAATAACAGT AGGGCTCCTG GCCATGACCG CAGGTCTACT TATTCACTTT 
TTAGCTTTTG ACAAGAGAGC TTACTTTTAT CATAGCAACT TTCATATCCT AAATGTTGAC 
TATACTGAAG CTTTAAACTC ACCAGCTACG CATGAATACA GAACCTTGAG TGAAAGAATC 
GAGTCTATGA TTACTGATGC ATTTCGAGAA TCAAATCTAC GAAGTGAGTT TATCAGGACA 
CATGTTGTCA AACTGAGAAA AGAAGGGAGT GGTGTGGTTG CGGATGTTGT CATGAAATTT 
CGATCTAGTA AGCGTAACAA CAAAAAGGCA ATCAAAACCA GAATCCAATC TGTGCTACAA 
AGACTCAGCA GCTCTGGGAA CTTGGAAATA GCCCCTTCGA ATGGGATAAC ATCACTCACT 
GACCAGGATA CAGAAAATGT TTTGACTCAA GAATGTGGAG CACGTCCAGA CCTTATAACA 
CTGTCAGAAG AGAGAATCAT TGGAGGCACT CAAGCTGAGA CAGGTGACTG GCCCTGGCAA 
GTCAGTCTAC AGCTCAACAA TGTCCACCAC TGTGGAGGTA CCCTGATCAG TAACTTGTGG 
GTCCTGACAG CCGCTCACTG CTTCAGAAGC TACTCGAATC CTCAACAATG GACAGCCACC 
TTTGGTGTTT CTACAATAAG TCCTAGGTTA AGAGTGAGAG TAAGGGCTAT TTTAGCCCAT 
GCTGAGTACA ACTCCATAAC TCGTGATAAT GATATTGCAG TTGTACAACT TGACAGACCT 
GTCACCTTTA CCAGAAATAT CCATAGGGTA TGTCTCCCAG CAGCAACCCA AAATATCATG 
CCTGATTCCG TCGCATATGT CACAGGATGG GGATCTCTCA CTTATGGAGG CAACACGGTC 
ACAAATCTAC AGCAAGGAGA GGTCAGAATA GTAAGTTCGG AGGTGTGCAA CGAGCCAGCT 
GGCTACGGTG GGAGTGTCTT GCCAGGAATG CTCTGTGCTG GAGTCCGTTC AGGGGCCGTG 
GATGCATGCC AGGGTGATTC TGGTGGCCCA CTAGTACAAG AAGACACAAG GCGGCTTTGG 
TTTGTCGTGG GGATTGTGAG CTGGGGATAT CAATGTGGCC TGCCAAATAA GCCAGGAGTG 
TATACGCGAG TGACAGCCTA CCGCAACTGG ATTAGGCAGC AGACTGGAAT CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

TMPRSS2 and ADAM17 cleave ACE2 differentially and only proteolysis by TMPRSS2 augments entry driven by the severe acute respiratory syndrome coronavirus spike protein.
Journal of virology88(2)1293-307(2014 Jan)
Heurich A,Hofmann-Winkler H,Gierer S,Liepold T,Jahn O,P?hlmann S

Large-scale proteomics and phosphoproteomics of urinary exosomes.
Journal of the American Society of Nephrology : JASN20(2)363-79(2009 Feb)
Gonzales PA,Pisitkun T,Hoffert JD,Tchapyjnikov D,Star RA,Kleta R,Wang NS,Knepper MA

The adrenal secretory serine protease AsP is a short secretory isoform of the transmembrane airway trypsin-like protease.
Endocrinology145(4)1898-905(2004 Apr)
Hansen IA,Fassnacht M,Hahner S,Hammer F,Schammann M,Meyer SR,Bicknell AB,Allolio B

Identification of a serine protease involved with the regulation of adrenal growth.
Annals of the New York Academy of Sciences994118-22(2003 Jun)
Bicknell AB

Characterization of a serine protease that cleaves pro-gamma-melanotropin at the adrenal to stimulate growth.
Cell105(7)903-12(2001 Jun)
Bicknell AB,Lomthaisong K,Woods RJ,Hutchinson EG,Bennett HP,Gladwell RT,Lowry PJ

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Tmprss11d cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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