Synj2bp cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Synj2bp
Entrez Gene ID	64531
Full Name	synaptojanin 2 binding protein
Synonyms	Omp25
General protein information	Preferred Names synaptojanin 2 binding protein Names synaptojanin-2-binding protein NPW16 mitochondrial outer membrane protein 25 outer membrane protein
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 6 Map Location: 6q24
Summary	binds and recruits synaptojanin 2A to mitochondria; facilitates synaptojanin 2A mediated inositol phosphate modification activity that may regulate intracellular distribution of mitochondria [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_022599.2	NP_072121.2	synaptojanin-2-binding protein

Pathways from BioSystems

Homologies

Gallus gallus (chicken)	SYNJ2BP	NP_001264717.1
Danio rerio (zebrafish)	synj2bp	NP_956211.1
Rattus norvegicus (Norway rat)	Synj2bp	NP_072121.2
Canis lupus familiaris (dog)	SYNJ2BP	NP_001239272.1
Homo sapiens (human)	SYNJ2BP	NP_060843.2
	SYNJ2BP	XP_001111113.1
Mus musculus (house mouse)	Synj2bp	NP_079568.1
Xenopus tropicalis (tropical clawed frog)	synj2bp	NP_001106384.1
Pan troglodytes (chimpanzee)	SYNJ2BP	NP_001230053.1
Bos taurus (cattle)	SYNJ2BP	NP_001030432.1

Gene Ontology
Bibliography

Related articles in PubMed

Synaptojanin-2 binding protein stabilizes the Notch ligands DLL1 and DLL4 and inhibits sprouting angiogenesis.
Adam MG, Berger C, Feldner A, Yang WJ, W?stehube-Lausch J, Herberich SE, Pinder M, Gesierich S, Hammes HP, Augustin HG, Fischer A
Circulation research113(11)1206-18(2013 Nov)

The mitochondrial outer membrane protein hFis1 regulates mitochondrial morphology and fission through self-interaction.
Serasinghe MN, Yoon Y
Experimental cell research314(19)3494-507(2008 Nov)

Characterization of isoforms of activin receptor-interacting protein 2 that augment activin signaling.
Liu ZH, Tsuchida K, Matsuzaki T, Bao YL, Kurisaki A, Sugino H
The Journal of endocrinology189(2)409-21(2006 May)

The Abl/Arg substrate ArgBP2/nArgBP2 coordinates the function of multiple regulatory mechanisms converging on the actin cytoskeleton.
Cestra G, Toomre D, Chang S, De Camilli P
Proceedings of the National Academy of Sciences of the United States of America102(5)1731-6(2005 Feb)

Regulation of endocytosis of activin type II receptors by a novel PDZ protein through Ral/Ral-binding protein 1-dependent pathway.
Matsuzaki T, Hanai S, Kishi H, Liu Z, Bao Y, Kikuchi A, Tsuchida K, Sugino H
The Journal of biological chemistry277(21)19008-18(2002 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Synj2bp gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Synj2bp cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa06095	NM_022599.2 Latest version!	Rattus norvegicus synaptojanin 2 binding protein (Synj2bp), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Synj2bp ( NM_022599.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_072121.2 Rattus norvegicus synaptojanin 2 binding protein (Synj2bp), mRNA.

Price & Availability↑

CloneID	ORa06095
Clone ID Related Accession (Same CDS sequence)	NM_022599.2
Accession Version	NM_022599.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 438bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-22
Organism	Rattus norvegicus(Norway rat)
Product	synaptojanin-2-binding protein
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AF260258.1 and AABR07065042.1. On Oct 14, 2005 this sequence version replaced NM_022599.1. Sequence Note: This RefSeq record was created using sequences from two different strains, Sprague-Dawley and BN/SsNHsdMCW, because no single transcript from the same strain was available for the full length of the gene. ##Evidence-Data-START## Transcript exon combination :: AF260258.1, BC126067.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01906350 [ECO:0000348] ##Evidence-Data-END##

ATGAACGGAC GGGTGGATTA TTTAGTCTCC GAGGAAGAGA TCAACCTGAC CAGAGGACCC 
TCGGGGCTGG GCTTCAACAT CGTCGGTGGG ACAGATCAAC AGTATGTCTC CAATGACAGT 
GGCATCTACG TCAGCCGCAT CAAAGAGGAT GGGGCTGCGG CCCGGGATGG GCGGCTCCAG 
GAGGGTGATA AGATCCTCTC GGTAAATGGC CAAGACCTGA AGAACCTGTT GCACCAAGAT 
GCCGTAGACC TCTTCCGTAA TGCAGGATAT GCCGTGTCCC TGAGAGTGCA GCACAGGTTA 
CCAGTGCAGA ATGGACCTAT AGTTCATCGA GGCGACGGAG AGCCGAGTGG AGTTCCTGTA 
GCTGTGGTGC TGCTGCCAGT GTTTGCCCTT ACCCTGGTAG CAGTTTGGGC CTTCGTGAGA 
TACCGAAAGC AGCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_072121.2
CDS	85..522
Translation	MNGRVDYLVSEEEINLTRGPSGLGFNIVGGTDQQYVSNDSGIYVSRIKEDGAAARDGRLQEGDKILSVNGQDLKNLLHQDAVDLFRNAGYAVSLRVQHRLPVQNGPIVHRGDGEPSGVPVAVVLLPVFALTLVAVWAFVRYRKQL

Target ORF information:

RefSeq Version	NM_022599.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus synaptojanin 2 binding protein (Synj2bp), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022599.2

ORF Insert Sequence:

ATGAACGGAC GGGTGGATTA TTTAGTCTCC GAGGAAGAGA TCAACCTGAC CAGAGGACCC 
TCGGGGCTGG GCTTCAACAT CGTCGGTGGG ACAGATCAAC AGTATGTCTC CAATGACAGT 
GGCATCTACG TCAGCCGCAT CAAAGAGGAT GGGGCTGCGG CCCGGGATGG GCGGCTCCAG 
GAGGGTGATA AGATCCTCTC GGTAAATGGC CAAGACCTGA AGAACCTGTT GCACCAAGAT 
GCCGTAGACC TCTTCCGTAA TGCAGGATAT GCCGTGTCCC TGAGAGTGCA GCACAGGTTA 
CCAGTGCAGA ATGGACCTAT AGTTCATCGA GGCGACGGAG AGCCGAGTGG AGTTCCTGTA 
GCTGTGGTGC TGCTGCCAGT GTTTGCCCTT ACCCTGGTAG CAGTTTGGGC CTTCGTGAGA 
TACCGAAAGC AGCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Synaptojanin-2 binding protein stabilizes the Notch ligands DLL1 and DLL4 and inhibits sprouting angiogenesis.
Circulation research113(11)1206-18(2013 Nov)
Adam MG,Berger C,Feldner A,Yang WJ,W?stehube-Lausch J,Herberich SE,Pinder M,Gesierich S,Hammes HP,Augustin HG,Fischer A

The mitochondrial outer membrane protein hFis1 regulates mitochondrial morphology and fission through self-interaction.
Experimental cell research314(19)3494-507(2008 Nov)
Serasinghe MN,Yoon Y

Characterization of isoforms of activin receptor-interacting protein 2 that augment activin signaling.
The Journal of endocrinology189(2)409-21(2006 May)
Liu ZH,Tsuchida K,Matsuzaki T,Bao YL,Kurisaki A,Sugino H

The Abl/Arg substrate ArgBP2/nArgBP2 coordinates the function of multiple regulatory mechanisms converging on the actin cytoskeleton.
Proceedings of the National Academy of Sciences of the United States of America102(5)1731-6(2005 Feb)
Cestra G,Toomre D,Chang S,De Camilli P

Regulation of endocytosis of activin type II receptors by a novel PDZ protein through Ral/Ral-binding protein 1-dependent pathway.
The Journal of biological chemistry277(21)19008-18(2002 May)
Matsuzaki T,Hanai S,Kishi H,Liu Z,Bao Y,Kikuchi A,Tsuchida K,Sugino H

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Synj2bp cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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