Niban1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Niban1
Entrez Gene ID	63912
Full Name	family with sequence similarity 129, member A
Synonyms	Niban
General protein information	Preferred Names family with sequence similarity 129, member A Names protein Niban
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 13 Map Location: 13q21
Summary	expressed in renal carcinomas in Tsc2 gene mutant Eker rats but is not expressed in normal kidney; may be a marker for early stage renal carcinogenesis [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_022242.2	NP_071578.2	protein Niban 1

Pathways from BioSystems

Homologies

	LOC714427	XP_001113897.1
Mus musculus (house mouse)	Fam129a	NP_071301.2
Gallus gallus (chicken)	FAM129A	NP_001012614.1
Homo sapiens (human)	FAM129A	NP_443198.1
Pan troglodytes (chimpanzee)	FAM129A	XP_001164202.1
Bos taurus (cattle)	FAM129A	NP_001178211.1
Danio rerio (zebrafish)	LOC561414	XP_689912.4
Rattus norvegicus (Norway rat)	Fam129a	NP_071578.2
Canis lupus familiaris (dog)	FAM129A	XP_537163.2

Gene Ontology
Bibliography

Related articles in PubMed

Defining the membrane proteome of NK cells.
Ghosh D, Lippert D, Krokhin O, Cortens JP, Wilkins JA
Journal of mass spectrometry : JMS45(1)1-25(2010 Jan)

The endoplasmic reticulum stress-inducible protein Niban regulates eIF2alpha and S6K1/4E-BP1 phosphorylation.
Sun GD, Kobayashi T, Abe M, Tada N, Adachi H, Shiota A, Totsuka Y, Hino O
Biochemical and biophysical research communications360(1)181-7(2007 Aug)

A novel tumor marker, Niban, is expressed in subsets of thyroid tumors and Hashimoto's thyroiditis.
Matsumoto F, Fujii H, Abe M, Kajino K, Kobayashi T, Matsumoto T, Ikeda K, Hino O
Human pathology37(12)1592-600(2006 Dec)

A novel gene "Niban" upregulated in renal carcinogenesis: cloning by the cDNA-amplified fragment length polymorphism approach.
Majima S, Kajino K, Fukuda T, Otsuka F, Hino O
Japanese journal of cancer research : Gann91(9)869-74(2000 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Together these results suggest that Niban is involved in the ER stress response, and that Niban can modulate cell death signaling by regulating translation.
Title: The endoplasmic reticulum stress-inducible protein Niban regulates eIF2alpha and S6K1/4E-BP1 phosphorylation.

The following Niban1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Niban1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa05521	NM_022242.2 Latest version!	Rattus norvegicus niban apoptosis regulator 1 (Niban1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Niban1 ( NM_022242.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_071578.2 Rattus norvegicus niban apoptosis regulator 1 (Niban1), mRNA.

Price & Availability↑

CloneID	ORa05521
Clone ID Related Accession (Same CDS sequence)	NM_022242.2
Accession Version	NM_022242.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2814bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Rattus norvegicus(Norway rat)
Product	protein Niban 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AB046718.2. On Jul 25, 2001 this sequence version replaced NM_022242.1. ##Evidence-Data-START## Transcript exon combination :: AB046718.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGGCGGCT CAGCCTCCAG CCAACTGGAT GAGGGCAAGT GCGCCTATAT CCGAGGGAAA 
ACTGAGGCTT CTATCAAAAA CTTCAGTCCC TACTACAGCC GCCAATATTC TGTGGCTTTC 
TGCAACCATG TGCGCAGCGA GGTGGAACAG CAGAGAGATT TAACGTCACA GTTTCTGAAG 
ACCAAGCCCC CACTGGAACC AGGAACTGTT TTGTATGAAG CTGAGCTCTC ACAGTTTGCT 
GAGGACATCA GGAAATGGAA GGACAGATAC GTTGTGGTTA AAAACGATTT TGCTGTGGAA 
AGCTATGAGA ACAAAGAGGC CTATCAGAGA GGAGCTGTTC CTAAAAGCAG AATTCTTCCA 
GCTGGTGGCA AGGTGTTAAC CTCAGAAGAG GAATATAGTC TCTTATCTGA TAAGCATTTC 
CCAGACCCCA CTGCTTCCAG TGAGAAGAAC TCTCAGCCCT TCCTGGTCCT ACCCAAGGCA 
TTCCCAGTGT ACCTGTGGCA GCCTTACCTC AGGCACGGCT ACTTCTGTTT CCACGAGGCT 
GCCGAGCAGC AGAAGTTCAG CGCTCTTCTC AACGACTGCA TCAGACACCT GAATCACGAT 
TACATGAAGC AGACCACATT CGAAGCCCAA GCCTTTTTGG AAGCTGTGCA GTTCTTCCGG 
CAGGAGAAGG GTCACTACGG CGCCTGGGAA GTGATTACTG GAGATGAAGT CCAGATCCTG 
AGTAAACTGG TGATGGAGGA GCTCCTGCCG ACCCTCCAGA CTGACCTGCT GCCTAAACTG 
AAGGGGAAGA AGAATGACAG AAAGAGAGCC TGGTTTGGAC TCCTGGAGGA AGCCTACAAT 
CTGGTTCAGC ACCAAGTTTC AGAAGGATTA AGTGCCTTGA AGGAGGAGTG CAGAGCTCTG 
ACAAAGGACC TGGAAGGGAC CATCCGCTCA GACATGGATC AGATTGTGAA CTCAAAGAAC 
TTTCTAACTG GGAAGATCAG AGCAATGGTG GCTCAGCCGG CCGAGAATCG CTGTGGGGAA 
AGTGTGCAGC CCTTCCTGGC ATCCATTCTG GAGGAGCTAA TGGGGCCGGT GAGCTCCGGT 
TTCAGTGAAG TCCGTGCACT TTTCGAAAAA GAAGTAGATG AACTCAGTCA GAGCTTCCAC 
ACCACCCAGG ACGGTGCCCA GCTGAAGGAG TGTCTAGACC AGCTAATGAA GCTTCCTCTG 
GATTCTGTGA AGATGGAGCC TTGTTACACT AAAGTCACCC TGCTTCCAGA GCGCCTGCTG 
GACCTCCAGA GTCGCTTCAG ATTCCCTCAC GTTGATCTGG TGGTCCAGAG GACTCAGAAC 
TACATGCAGG AGCTCATGGA GAATGCTGTG TTCACATTTG AGCAGTTGCT CTCCCCATAT 
CTTCAAGGAG AGGCTTCCAG AACAGCAGTG GCCATCGAGA AGGTTAAGCT CCGTGTCTTA 
AAGCAATACG ATTACGACAG CAGCACCATC CGCAAGAAGA TCTTCCAGGA GGCATTGATT 
CAGATCACAC TACCCACTGT GCAGAAGGCG CTGGCGTCCA CATGCAAACC AGAGCTTCAG 
AAATATGAGC AGTTCATCTT CGCAGACCAC ACCAATATGA TCCATGTTGA GAACATCTAT 
GAAGAGATTT TGTATCAGAT CCTCCTCGAT GAGACCCTGA AAGTGATAAC GGAAGCAGCT 
ATCTTGAAGA AACACAACTT ATTTGAAGAC AACATGGCCT TACCCAGTGA AAGTGTGTCC 
AGTCTGACAG ACCTCAAAAC CTCCATGGGG TCAAACCAGG CCAGCCCAGC CAGAGGAGCA 
TCTGCCATTC TCCCAGGAGC TCCAGGCGAT GAGGCTCCAG GCAGCGAAGT GTTCCAGGGG 
CCTGAGGAAA AGCAGCAGCA GCCTGGGGTC CCTGGCTCGC TGGCCAGAGA AGAAAGTGCT 
TCCATCTCTG GGTCCAGCCC TCCTTCAGGT GAGGATGGGC AGGTGTCTGT GTCCGGTGTG 
GATAACTCTG CCGGGAACCC TCTCAGTGCA GATAATTCAG CAGGACCTCT CAGCTCACAC 
TTGTCAGAGG CAGAAGCTGG GGAGCCCCCT AAAGATGAGG AAACAGCCCA CAAAAGGCCA 
GAGTCTAGCG CCGTGCCAGG GTCCTTGAGG GAACTGAAGG AGTTGTTGAC TGTGACGGTG 
TTCGTCGAGT CTGCCCCAGA GATTGGAAAT GATACACTCA ACGGGACACC TGTTCCCCAA 
GAAGATAAAA AAGAAGAAGA AGAGGAGGAG GAAAGCAAGA TCCACCCAGA AGCCAGCGGC 
CCAGCTGCCA TCCAGCAGGA CAGCTGTGAA GAAAGTGAAG TCAGAGAGAG GGAGGCCCAT 
CCTATGCCTT TGGAAGCTGA GGCTCCTGGG GTGAACTTGG GGACACTGCC AGAGGGTAGA 
GGGCCTACCT CTCAGTCTAC CGGTGAGGGA CTCACTGAGA ACACCAGCTG TCTAGGCCCC 
ATAGAGGAGC CATCTGAGGC TCAAGGGCCC ACTGAGGAGG TGCTCCTAGC CACAGTTTCC 
ACACAGGACA GCACCGAGGC AGGAGGTGAG GCTGTGCATT CTGTGACAGT CACACCTCAA 
GAAGATGCCA CGTTAAGTTC TAACCCCATC TGTCCCGTGG AGAATAATGA GGGGCCCCAG 
GTTTCTGAGG ATCAGGAAGT GCTGGGAGGG AATGATAGCC CAGCCCTTGC TATGGATACA 
GAGCAAATCA ACGATGCCCA TGTGTATGAG TGCCACTGGG AGGTAGAAGA TGCCCCGAGC 
GCCGACATCC TAGATGTTCA CGATTGTGAT GTGGGCTCCC CAGGGGAGTG GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_071578.2
CDS	32..2845
Translation	MGGSASSQLDEGKCAYIRGKTEASIKNFSPYYSRQYSVAFCNHVRSEVEQQRDLTSQFLKTKPPLEPGTVLYEAELSQFAEDIRKWKDRYVVVKNDFAVESYENKEAYQRGAVPKSRILPAGGKVLTSEEEYSLLSDKHFPDPTASSEKNSQPFLVLPKAFPVYLWQPYLRHGYFCFHEAAEQQKFSALLNDCIRHLNHDYMKQTTFEAQAFLEAVQFFRQEKGHYGAWEVITGDEVQILSKLVMEELLPTLQTDLLPKLKGKKNDRKRAWFGLLEEAYNLVQHQVSEGLSALKEECRALTKDLEGTIRSDMDQIVNSKNFLTGKIRAMVAQPAENRCGESVQPFLASILEELMGPVSSGFSEVRALFEKEVDELSQSFHTTQDGAQLKECLDQLMKLPLDSVKMEPCYTKVTLLPERLLDLQSRFRFPHVDLVVQRTQNYMQELMENAVFTFEQLLSPYLQGEASRTAVAIEKVKLRVLKQYDYDSSTIRKKIFQEALIQITLPTVQKALASTCKPELQKYEQFIFADHTNMIHVENIYEEILYQILLDETLKVITEAAILKKHNLFEDNMALPSESVSSLTDLKTSMGSNQASPARGASAILPGAPGDEAPGSEVFQGPEEKQQQPGVPGSLAREESASISGSSPPSGEDGQVSVSGVDNSAGNPLSADNSAGPLSSHLSEAEAGEPPKDEETAHKRPESSAVPGSLRELKELLTVTVFVESAPEIGNDTLNGTPVPQEDKKEEEEEEESKIHPEASGPAAIQQDSCEESEVREREAHPMPLEAEAPGVNLGTLPEGRGPTSQSTGEGLTENTSCLGPIEEPSEAQGPTEEVLLATVSTQDSTEAGGEAVHSVTVTPQEDATLSSNPICPVENNEGPQVSEDQEVLGGNDSPALAMDTEQINDAHVYECHWEVEDAPSADILDVHDCDVGSPGEW

Target ORF information:

RefSeq Version	NM_022242.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus niban apoptosis regulator 1 (Niban1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022242.2

ORF Insert Sequence:

ATGGGCGGCT CAGCCTCCAG CCAACTGGAT GAGGGCAAGT GCGCCTATAT CCGAGGGAAA 
ACTGAGGCTT CTATCAAAAA CTTCAGTCCC TACTACAGCC GCCAATATTC TGTGGCTTTC 
TGCAACCATG TGCGCAGCGA GGTGGAACAG CAGAGAGATT TAACGTCACA GTTTCTGAAG 
ACCAAGCCCC CACTGGAACC AGGAACTGTT TTGTATGAAG CTGAGCTCTC ACAGTTTGCT 
GAGGACATCA GGAAATGGAA GGACAGATAC GTTGTGGTTA AAAACGATTT TGCTGTGGAA 
AGCTATGAGA ACAAAGAGGC CTATCAGAGA GGAGCTGTTC CTAAAAGCAG AATTCTTCCA 
GCTGGTGGCA AGGTGTTAAC CTCAGAAGAG GAATATAGTC TCTTATCTGA TAAGCATTTC 
CCAGACCCCA CTGCTTCCAG TGAGAAGAAC TCTCAGCCCT TCCTGGTCCT ACCCAAGGCA 
TTCCCAGTGT ACCTGTGGCA GCCTTACCTC AGGCACGGCT ACTTCTGTTT CCACGAGGCT 
GCCGAGCAGC AGAAGTTCAG CGCTCTTCTC AACGACTGCA TCAGACACCT GAATCACGAT 
TACATGAAGC AGACCACATT CGAAGCCCAA GCCTTTTTGG AAGCTGTGCA GTTCTTCCGG 
CAGGAGAAGG GTCACTACGG CGCCTGGGAA GTGATTACTG GAGATGAAGT CCAGATCCTG 
AGTAAACTGG TGATGGAGGA GCTCCTGCCG ACCCTCCAGA CTGACCTGCT GCCTAAACTG 
AAGGGGAAGA AGAATGACAG AAAGAGAGCC TGGTTTGGAC TCCTGGAGGA AGCCTACAAT 
CTGGTTCAGC ACCAAGTTTC AGAAGGATTA AGTGCCTTGA AGGAGGAGTG CAGAGCTCTG 
ACAAAGGACC TGGAAGGGAC CATCCGCTCA GACATGGATC AGATTGTGAA CTCAAAGAAC 
TTTCTAACTG GGAAGATCAG AGCAATGGTG GCTCAGCCGG CCGAGAATCG CTGTGGGGAA 
AGTGTGCAGC CCTTCCTGGC ATCCATTCTG GAGGAGCTAA TGGGGCCGGT GAGCTCCGGT 
TTCAGTGAAG TCCGTGCACT TTTCGAAAAA GAAGTAGATG AACTCAGTCA GAGCTTCCAC 
ACCACCCAGG ACGGTGCCCA GCTGAAGGAG TGTCTAGACC AGCTAATGAA GCTTCCTCTG 
GATTCTGTGA AGATGGAGCC TTGTTACACT AAAGTCACCC TGCTTCCAGA GCGCCTGCTG 
GACCTCCAGA GTCGCTTCAG ATTCCCTCAC GTTGATCTGG TGGTCCAGAG GACTCAGAAC 
TACATGCAGG AGCTCATGGA GAATGCTGTG TTCACATTTG AGCAGTTGCT CTCCCCATAT 
CTTCAAGGAG AGGCTTCCAG AACAGCAGTG GCCATCGAGA AGGTTAAGCT CCGTGTCTTA 
AAGCAATACG ATTACGACAG CAGCACCATC CGCAAGAAGA TCTTCCAGGA GGCATTGATT 
CAGATCACAC TACCCACTGT GCAGAAGGCG CTGGCGTCCA CATGCAAACC AGAGCTTCAG 
AAATATGAGC AGTTCATCTT CGCAGACCAC ACCAATATGA TCCATGTTGA GAACATCTAT 
GAAGAGATTT TGTATCAGAT CCTCCTCGAT GAGACCCTGA AAGTGATAAC GGAAGCAGCT 
ATCTTGAAGA AACACAACTT ATTTGAAGAC AACATGGCCT TACCCAGTGA AAGTGTGTCC 
AGTCTGACAG ACCTCAAAAC CTCCATGGGG TCAAACCAGG CCAGCCCAGC CAGAGGAGCA 
TCTGCCATTC TCCCAGGAGC TCCAGGCGAT GAGGCTCCAG GCAGCGAAGT GTTCCAGGGG 
CCTGAGGAAA AGCAGCAGCA GCCTGGGGTC CCTGGCTCGC TGGCCAGAGA AGAAAGTGCT 
TCCATCTCTG GGTCCAGCCC TCCTTCAGGT GAGGATGGGC AGGTGTCTGT GTCCGGTGTG 
GATAACTCTG CCGGGAACCC TCTCAGTGCA GATAATTCAG CAGGACCTCT CAGCTCACAC 
TTGTCAGAGG CAGAAGCTGG GGAGCCCCCT AAAGATGAGG AAACAGCCCA CAAAAGGCCA 
GAGTCTAGCG CCGTGCCAGG GTCCTTGAGG GAACTGAAGG AGTTGTTGAC TGTGACGGTG 
TTCGTCGAGT CTGCCCCAGA GATTGGAAAT GATACACTCA ACGGGACACC TGTTCCCCAA 
GAAGATAAAA AAGAAGAAGA AGAGGAGGAG GAAAGCAAGA TCCACCCAGA AGCCAGCGGC 
CCAGCTGCCA TCCAGCAGGA CAGCTGTGAA GAAAGTGAAG TCAGAGAGAG GGAGGCCCAT 
CCTATGCCTT TGGAAGCTGA GGCTCCTGGG GTGAACTTGG GGACACTGCC AGAGGGTAGA 
GGGCCTACCT CTCAGTCTAC CGGTGAGGGA CTCACTGAGA ACACCAGCTG TCTAGGCCCC 
ATAGAGGAGC CATCTGAGGC TCAAGGGCCC ACTGAGGAGG TGCTCCTAGC CACAGTTTCC 
ACACAGGACA GCACCGAGGC AGGAGGTGAG GCTGTGCATT CTGTGACAGT CACACCTCAA 
GAAGATGCCA CGTTAAGTTC TAACCCCATC TGTCCCGTGG AGAATAATGA GGGGCCCCAG 
GTTTCTGAGG ATCAGGAAGT GCTGGGAGGG AATGATAGCC CAGCCCTTGC TATGGATACA 
GAGCAAATCA ACGATGCCCA TGTGTATGAG TGCCACTGGG AGGTAGAAGA TGCCCCGAGC 
GCCGACATCC TAGATGTTCA CGATTGTGAT GTGGGCTCCC CAGGGGAGTG GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Defining the membrane proteome of NK cells.
Journal of mass spectrometry : JMS45(1)1-25(2010 Jan)
Ghosh D,Lippert D,Krokhin O,Cortens JP,Wilkins JA

The endoplasmic reticulum stress-inducible protein Niban regulates eIF2alpha and S6K1/4E-BP1 phosphorylation.
Biochemical and biophysical research communications360(1)181-7(2007 Aug)
Sun GD,Kobayashi T,Abe M,Tada N,Adachi H,Shiota A,Totsuka Y,Hino O

A novel tumor marker, Niban, is expressed in subsets of thyroid tumors and Hashimoto's thyroiditis.
Human pathology37(12)1592-600(2006 Dec)
Matsumoto F,Fujii H,Abe M,Kajino K,Kobayashi T,Matsumoto T,Ikeda K,Hino O

A novel gene "Niban" upregulated in renal carcinogenesis: cloning by the cDNA-amplified fragment length polymorphism approach.
Japanese journal of cancer research : Gann91(9)869-74(2000 Sep)
Majima S,Kajino K,Fukuda T,Otsuka F,Hino O

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Niban1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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