Tagln3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Tagln3
Entrez Gene ID	63837
Full Name	transgelin 3
Synonyms	Np22,Np25
General protein information	Preferred Names transgelin 3 Names transgelin-3 neuronal protein 22 neuronal protein Np25
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 11 Map Location: 11q21
Summary	human homolog mRNA has increased expression in the superior frontal cortex of alcoholics; may interact with cytoskeletal elements in the brain [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_031676.2	NP_113864.2	transgelin-3
NM_001035236.1	NP_001030313.1	transgelin-3

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	TAGLN3	XP_001154266.1
Bos taurus (cattle)	TAGLN3	NP_001029671.1
Mus musculus (house mouse)	Tagln3	NP_062728.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP000748	XP_311283.5
Homo sapiens (human)	TAGLN3	NP_037391.2
Danio rerio (zebrafish)	tagln3b	NP_956014.1
Canis lupus familiaris (dog)	TAGLN3	XP_535738.1
	TAGLN3	XP_002802683.1
Rattus norvegicus (Norway rat)	Tagln3	NP_001030313.1
Gallus gallus (chicken)	TAGLN3	XP_416634.1
Caenorhabditis elegans (roundworm)	cpn-2	NP_493713.2

Gene Ontology
Bibliography

Related articles in PubMed

A proteomic comparison of immature and mature mouse gonadotrophs reveals novel differentially expressed nuclear proteins that regulate gonadotropin gene transcription and RNA splicing.
Feng J, Lawson MA, Melamed P
Biology of reproduction79(3)546-61(2008 Sep)

Proteolipid protein is required for transport of sirtuin 2 into CNS myelin.
Werner HB, Kuhlmann K, Shen S, Uecker M, Schardt A, Dimova K, Orfaniotou F, Dhaunchak A, Brinkmann BG, M?bius W, Guarente L, Casaccia-Bonnefil P, Jahn O, Nave KA
The Journal of neuroscience : the official journal of the Society for Neuroscience27(29)7717-30(2007 Jul)

The novel cytoskeleton-associated protein Neuronal protein 22: elevated expression in the developing rat brain.
Depaz IM, Wilce PA
Brain research1081(1)59-64(2006 Apr)

Molecular cloning and characterization of hNP22: a gene up-regulated in human alcoholic brain.
Fan L, Jaquet V, Dodd PR, Chen W, Wilce PA
Journal of neurochemistry76(5)1275-81(2001 Mar)

The identification of NP25: a novel protein that is differentially expressed by neuronal subpopulations.
Ren WZ, Ng GY, Wang RX, Wu PH, O'Dowd BF, Osmond DH, George SR, Liew CC
Brain research. Molecular brain research22(1-4)173-85(1994 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

NP22 may play a role in mediating the molecular events governing development of the neuronal architecture. Furthermore, its sustained expression in postnatal brain implies a function in the maintenance of neuronal morphology.
Title: The novel cytoskeleton-associated protein Neuronal protein 22: elevated expression in the developing rat brain.

The following Tagln3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Tagln3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa12787	NM_031676.2 Latest version!	Rattus norvegicus transgelin 3 (Tagln3), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
ORa12787	NM_001035236.1 Latest version!	Rattus norvegicus transgelin 3 (Tagln3), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Tagln3 ( NM_031676.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_113864.2 Rattus norvegicus transgelin 3 (Tagln3), transcript variant 2, mRNA.

Price & Availability↑

CloneID	ORa12787
Clone ID Related Accession (Same CDS sequence)	NM_031676.2 , NM_001035236.1
Accession Version	NM_031676.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 600bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-22
Organism	Rattus norvegicus(Norway rat)
Product	transgelin-3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CB795348.1, AF459788.1 and M84725.1. On Oct 28, 2005 this sequence version replaced NM_031676.1. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: FQ212759.1, FQ212858.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTAACA GGGGTCCGAG CTACGGCTTA AGCCGAGAGG TGCAGGAGAA GATTGAGCAG 
AAATATGACG CGGACCTGGA GAACAAGCTG GTGGACTGGA TCATCCTGCA GTGTGCTGAG 
GATATAGAGC ACCCGCCCCC GGGCAGGACC CATTTTCAGA AATGGTTGAT GGACGGGACG 
GTCCTGTGCA AGCTGATAAA CAGTTTATAT CCACCAGGAC AAGAACCCAT CCCCAAGATC 
TCAGAGTCAA AGATGGCTTT TAAGCAGATG GAGCAAATCT CTCAGTTCCT GAAGGCTGCC 
GAGGTCTATG GCGTCAGGAC CACTGACATT TTTCAAACAG TGGATCTATG GGAAGGGAAG 
GACATGGCAG CTGTGCAGAG GACTCTGATG GCTCTGGGAA GCGTTGCAGT TACCAAGGAT 
GATGGCTGCT ACCGGGGAGA GCCGTCCTGG TTTCACAGGA AAGCCCAGCA GAATCGGAGA 
GGATTTTCAG AGGAGCAACT TCGCCAGGGA CAGAATGTCA TAGGCCTGCA GATGGGCAGC 
AACAAGGGTG CCTCCCAGGC AGGCATGACG GGGTACGGGA TGCCCAGGCA GATCATGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_113864.2
CDS	95..694
Translation	MANRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRTHFQKWLMDGTVLCKLINSLYPPGQEPIPKISESKMAFKQMEQISQFLKAAEVYGVRTTDIFQTVDLWEGKDMAAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQMGSNKGASQAGMTGYGMPRQIM

Target ORF information:

RefSeq Version	NM_031676.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus transgelin 3 (Tagln3), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_031676.2

ORF Insert Sequence:

ATGGCTAACA GGGGTCCGAG CTACGGCTTA AGCCGAGAGG TGCAGGAGAA GATTGAGCAG 
AAATATGACG CGGACCTGGA GAACAAGCTG GTGGACTGGA TCATCCTGCA GTGTGCTGAG 
GATATAGAGC ACCCGCCCCC GGGCAGGACC CATTTTCAGA AATGGTTGAT GGACGGGACG 
GTCCTGTGCA AGCTGATAAA CAGTTTATAT CCACCAGGAC AAGAACCCAT CCCCAAGATC 
TCAGAGTCAA AGATGGCTTT TAAGCAGATG GAGCAAATCT CTCAGTTCCT GAAGGCTGCC 
GAGGTCTATG GCGTCAGGAC CACTGACATT TTTCAAACAG TGGATCTATG GGAAGGGAAG 
GACATGGCAG CTGTGCAGAG GACTCTGATG GCTCTGGGAA GCGTTGCAGT TACCAAGGAT 
GATGGCTGCT ACCGGGGAGA GCCGTCCTGG TTTCACAGGA AAGCCCAGCA GAATCGGAGA 
GGATTTTCAG AGGAGCAACT TCGCCAGGGA CAGAATGTCA TAGGCCTGCA GATGGGCAGC 
AACAAGGGTG CCTCCCAGGC AGGCATGACG GGGTACGGGA TGCCCAGGCA GATCATGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Tagln3 ( NM_001035236.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001030313.1 Rattus norvegicus transgelin 3 (Tagln3), transcript variant 1, mRNA.

Price & Availability↑

CloneID	ORa12787
Clone ID Related Accession (Same CDS sequence)	NM_031676.2 , NM_001035236.1
Accession Version	NM_001035236.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 600bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-23
Organism	Rattus norvegicus(Norway rat)
Product	transgelin-3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AF459788.1 and M84725.1. Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: AF459788.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTAACA GGGGTCCGAG CTACGGCTTA AGCCGAGAGG TGCAGGAGAA GATTGAGCAG 
AAATATGACG CGGACCTGGA GAACAAGCTG GTGGACTGGA TCATCCTGCA GTGTGCTGAG 
GATATAGAGC ACCCGCCCCC GGGCAGGACC CATTTTCAGA AATGGTTGAT GGACGGGACG 
GTCCTGTGCA AGCTGATAAA CAGTTTATAT CCACCAGGAC AAGAACCCAT CCCCAAGATC 
TCAGAGTCAA AGATGGCTTT TAAGCAGATG GAGCAAATCT CTCAGTTCCT GAAGGCTGCC 
GAGGTCTATG GCGTCAGGAC CACTGACATT TTTCAAACAG TGGATCTATG GGAAGGGAAG 
GACATGGCAG CTGTGCAGAG GACTCTGATG GCTCTGGGAA GCGTTGCAGT TACCAAGGAT 
GATGGCTGCT ACCGGGGAGA GCCGTCCTGG TTTCACAGGA AAGCCCAGCA GAATCGGAGA 
GGATTTTCAG AGGAGCAACT TCGCCAGGGA CAGAATGTCA TAGGCCTGCA GATGGGCAGC 
AACAAGGGTG CCTCCCAGGC AGGCATGACG GGGTACGGGA TGCCCAGGCA GATCATGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001030313.1
CDS	147..746
Translation	MANRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRTHFQKWLMDGTVLCKLINSLYPPGQEPIPKISESKMAFKQMEQISQFLKAAEVYGVRTTDIFQTVDLWEGKDMAAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQMGSNKGASQAGMTGYGMPRQIM

Target ORF information:

RefSeq Version	NM_001035236.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus transgelin 3 (Tagln3), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001035236.1

ORF Insert Sequence:

ATGGCTAACA GGGGTCCGAG CTACGGCTTA AGCCGAGAGG TGCAGGAGAA GATTGAGCAG 
AAATATGACG CGGACCTGGA GAACAAGCTG GTGGACTGGA TCATCCTGCA GTGTGCTGAG 
GATATAGAGC ACCCGCCCCC GGGCAGGACC CATTTTCAGA AATGGTTGAT GGACGGGACG 
GTCCTGTGCA AGCTGATAAA CAGTTTATAT CCACCAGGAC AAGAACCCAT CCCCAAGATC 
TCAGAGTCAA AGATGGCTTT TAAGCAGATG GAGCAAATCT CTCAGTTCCT GAAGGCTGCC 
GAGGTCTATG GCGTCAGGAC CACTGACATT TTTCAAACAG TGGATCTATG GGAAGGGAAG 
GACATGGCAG CTGTGCAGAG GACTCTGATG GCTCTGGGAA GCGTTGCAGT TACCAAGGAT 
GATGGCTGCT ACCGGGGAGA GCCGTCCTGG TTTCACAGGA AAGCCCAGCA GAATCGGAGA 
GGATTTTCAG AGGAGCAACT TCGCCAGGGA CAGAATGTCA TAGGCCTGCA GATGGGCAGC 
AACAAGGGTG CCTCCCAGGC AGGCATGACG GGGTACGGGA TGCCCAGGCA GATCATGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A proteomic comparison of immature and mature mouse gonadotrophs reveals novel differentially expressed nuclear proteins that regulate gonadotropin gene transcription and RNA splicing.
Biology of reproduction79(3)546-61(2008 Sep)
Feng J,Lawson MA,Melamed P

Proteolipid protein is required for transport of sirtuin 2 into CNS myelin.
The Journal of neuroscience : the official journal of the Society for Neuroscience27(29)7717-30(2007 Jul)
Werner HB,Kuhlmann K,Shen S,Uecker M,Schardt A,Dimova K,Orfaniotou F,Dhaunchak A,Brinkmann BG,M?bius W,Guarente L,Casaccia-Bonnefil P,Jahn O,Nave KA

The novel cytoskeleton-associated protein Neuronal protein 22: elevated expression in the developing rat brain.
Brain research1081(1)59-64(2006 Apr)
Depaz IM,Wilce PA

Molecular cloning and characterization of hNP22: a gene up-regulated in human alcoholic brain.
Journal of neurochemistry76(5)1275-81(2001 Mar)
Fan L,Jaquet V,Dodd PR,Chen W,Wilce PA

The identification of NP25: a novel protein that is differentially expressed by neuronal subpopulations.
Brain research. Molecular brain research22(1-4)173-85(1994 Mar)
Ren WZ,Ng GY,Wang RX,Wu PH,O'Dowd BF,Osmond DH,George SR,Liew CC