Clock cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Clock
Entrez Gene ID	60447
Full Name	clock circadian regulator
General protein information	Preferred Names clock circadian regulator Names circadian locomoter output cycles protein kaput circadian locomoter output cycles kaput rCLOCK
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 14 Map Location: 14p11
Summary	The protein encoded by this gene plays a central role in the regulation of circadian rhythms. The protein encodes a transcription factor of the basic helix-loop-helix (bHLH) family and contains DNA binding histone acetyltransferase activity. The encoded protein forms a heterodimer with Arntl (Bmal1) that binds E-box enhancer elements upstream of Period (Per1, Per2, Per3) and Cryptochrome (Cry1, Cry2) genes and activates transcription of these genes. Per and Cry proteins heterodimerize and repress their own transcription by interacting in a feedback loop with Clock/Arntl complexes. Polymorphisms in this gene may be associated with behavioral changes, obesity, and metabolic syndrome. Two transcripts encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2014].

mRNA and Protein(s)

mRNA	Protein	Name
XM_006250870.3	XP_006250932.1	circadian locomoter output cycles protein kaput isoform X2
NM_001289832.1	NP_001276761.1	circadian locomoter output cycles protein kaput isoform S
NM_021856.2	NP_068628.1	circadian locomoter output cycles protein kaput isoform 1
XM_017599362.1	XP_017454851.1	circadian locomoter output cycles protein kaput isoform X1
XM_017599363.1	XP_017454852.1	circadian locomoter output cycles protein kaput isoform X1
XM_006250869.3	XP_006250931.1	circadian locomoter output cycles protein kaput isoform X1
XM_017599361.1	XP_017454850.1	circadian locomoter output cycles protein kaput isoform X1
XM_017599364.1	XP_017454853.1	circadian locomoter output cycles protein kaput isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	CLOCK	NP_004889.1
Mus musculus (house mouse)	Clock	NP_031741.1
Bos taurus (cattle)	CLOCK	XP_005208040.1
Rattus norvegicus (Norway rat)	Clock	NP_068628.1
Xenopus tropicalis (tropical clawed frog)	clock	NP_001122127.1
	LOC697532	XP_002804151.1
Gallus gallus (chicken)	CLOCK	NP_989505.2
Danio rerio (zebrafish)	clock	NP_571032.1
Pan troglodytes (chimpanzee)	CLOCK	XP_001143582.1
Canis lupus familiaris (dog)	CLOCK	XP_005628257.1

Gene Ontology
Bibliography

Related articles in PubMed

CLOCK Acetylates ASS1 to Drive Circadian Rhythm of Ureagenesis.
Lin R, Mo Y, Zha H, Qu Z, Xie P, Zhu ZJ, Xu Y, Xiong Y, Guan KL
Molecular cell68(1)198-209.e6(2017 Oct)

[Expression profiles of miRNA-182 and Clock mRNA in the pineal gland of neonatal rats with hypoxic-ischemic brain damage].
Han X, Ding X, Xu LX, Liu MH, Feng X
Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics18(3)270-6(2016 Mar)

A role for the circadian clock protein Per1 in the regulation of the NaCl co-transporter (NCC) and the with-no-lysine kinase (WNK) cascade in mouse distal convoluted tubule cells.
Richards J, Ko B, All S, Cheng KY, Hoover RS, Gumz ML
The Journal of biological chemistry289(17)11791-806(2014 Apr)

A novel protein, CHRONO, functions as a core component of the mammalian circadian clock.
Goriki A, Hatanaka F, Myung J, Kim JK, Yoritaka T, Tanoue S, Abe T, Kiyonari H, Fujimoto K, Kato Y, Todo T, Matsubara A, Forger D, Takumi T
PLoS biology12(4)e1001839(2014 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Clock mRNA expression in the hypoxic-ischemic brain damage (HIBD) group increased at 0 hour after HIBD, decreased at 48 hours after HIBD and increased at 72 hours after HIBD (P<0.05).
Title: [Expression profiles of miRNA-182 and Clock mRNA in the pineal gland of neonatal rats with hypoxic-ischemic brain damage].

A phase advance in rhythmic clock gene expression in the heart and kidney of diabetic rats.
Title: Effect of streptozotocin-induced diabetes on clock gene expression in tissues inside and outside the blood-brain barrier in rat.

CLOCK protein in the hippocampus but not the suprachiasmatic nucleus plays an important role in long-lasting depressive-like behavior induced by chronic unpredictable stress.
Title: Hippocampal CLOCK protein participates in the persistence of depressive-like behavior induced by chronic unpredictable stress.

both CLOCK and BMAL1 may be involved the regulatory mechanism of circadian disorders in rats with hypoxic-ischemic brain damage
Title: [Changes of biological clock protein in neonatal rats with hypoxic-ischemic brain damage].

Using in silico analysis, study identified 10 sequence motifs that are correlated with the circadian phases of gene expression in the cartilage. One of these motifs, an E-box-like clock-related element (EL-box; GGCACGAGGC), can mediate BMAL1/CLOCK-induced transcription, which is typically regulated through an E-box or E'-box.
Title: Identification of a new clock-related element EL-box involved in circadian regulation by BMAL1/CLOCK and HES1.

The following Clock gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Clock cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa12715	NM_001289832.1 Latest version!	Rattus norvegicus clock circadian regulator (Clock), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$391.30 $559.00
ORa12956	NM_021856.2 Latest version!	Rattus norvegicus clock circadian regulator (Clock), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$475.30 $679.00
ORa36000	XM_006250869.3 Latest version!	Rattus norvegicus clock circadian regulator (Clock), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$475.30 $679.00
ORa36000	XM_017599362.1 Latest version!	Rattus norvegicus clock circadian regulator (Clock), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$475.30 $679.00
ORa36000	XM_017599361.1 Latest version!	Rattus norvegicus clock circadian regulator (Clock), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$475.30 $679.00
ORa36000	XM_017599364.1 Latest version!	Rattus norvegicus clock circadian regulator (Clock), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$475.30 $679.00
ORa36000	XM_017599363.1 Latest version!	Rattus norvegicus clock circadian regulator (Clock), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$475.30 $679.00
ORa36001	XM_006250870.3 Latest version!	Rattus norvegicus clock circadian regulator (Clock), transcript variant X6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$475.30 $679.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Clock ( NM_001289832.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001276761.1 Rattus norvegicus clock circadian regulator (Clock), transcript variant 2, mRNA.

Price & Availability↑

CloneID	ORa12715
Clone ID Related Accession (Same CDS sequence)	NM_001289832.1
Accession Version	NM_001289832.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2499bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-24
Organism	Rattus norvegicus(Norway rat)
Product	circadian locomoter output cycles protein kaput isoform S
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AB019259.1 and AC116236.5. Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (S) has the same N- and C-termini but is shorter compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB019259.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTTGTTTA CCGTAAGCTG TAGTAAAATG AGCTCAATTG TTGACAGAGA TGACAGTAGT 
ATTTTTGATG GATTGGTGGA AGAAGATGAC AAGGACAAAG CAAAAAGAGT ATCTAGAAAC 
AAATCAGAAA AGAAACGTAG AGATCAGTTC AATGTACTCA TTAAGGAACT GGGGTCTATG 
CTTCCTGGTA ATGCTAGAAA GATGGACAAG TCTACTGTTC TACAGAAGAG CATTGATTTT 
TTACGCAAAC ATAAAGAGAT CACTGCACAG TCAGATGCTA GTGAAATTCG ACAGGACTGG 
AAACCTACAT TCCTTAGTAA TGAAGAGTTT ACACAATTAA TGTTAGAGGC TCTTGATGGT 
TTTTTTTTAG CGATCATGAC AGATGGAAGT ATAATATATG TATCTGAGAC GGTAACTTCG 
TTACTTGAAC ATTTACCATC TGATCTTGTG GATCAAAGTA TATTTAATTT TATCCCAGAG 
GGAGAACATT CAGAGGTTTA TAAGATACTA TCTACTCACC TGCTGGAAAG TGACTCCTTA 
ACCCCCGAGG ACTTAAAATC AAAAAATCAG TTAGAATTCT GTTGTCACAT GCTTCGAGGA 
ACAATAGACC CAAAGGAGCC ATCCACCTAT GAATATGTGA GATTTATAGG AAATTTTAAA 
TCTTTAAACA GTGTATCAAC TTCAACACAT AATGGTTTCG AAGGAACTAT ACAGCGCACA 
CACAGGCCTT CTTATGAAGA TAGAGTTTGT TTCGTAGCTA CTGTCAGATT AGCTACCCCT 
CAGTTCATCA AGGAAATGTG TACTGTTGAA GAACCGAATG AAGAGTTCAC ATCTAGACAC 
AGTTTAGAAT GGAAGTTTCT ATTTCTAGAT CACAGGGCGC CGCCAATCAT AGGCTATCTG 
CCGTTTGAAG TCCTGGGAAC ATCAGGCTAT GATTACTATC ATGTGGACGA CCTAGAAAGT 
CTGGCAAAAT GTCATGAGCA CTTAATGCAA TATGGAAAAG GCAAATCATG TTACTATAGG 
TTCTTGACCA AAGGACAGCA GTGGATTTGG CTTCAGACTC ATTACTATAT CACTTACCAT 
CAGTGGAACT CAAGGCCAGA GTTCATCGTT TGTACTCACA CTGTAGTAAG TTATGCAGAA 
GTTAGGGCTG AAAGACGGCG AGAACTTGGC GTTGAGGAGT CTCTTCCCGA GACAGCTGCT 
GACAAAAGCC AAGATTCTGG GTCTGACAAT CGTATAAACA CAGTGAGTCT CAAGGAAGCA 
CTGGAAAGGT TCGATCACAG CCCAACTCCT TCTGCCTCCT CCAGAAGCTC AAGAAAGTCC 
TCGCACACAG CAGTCTCAGA CCCTTCCTCA ACGCCGACAA AGATCCCCAC TGATACTAGC 
ACTCCTCCCA GACCGCACCT GCCAGCTCAT GAGAAGATGA CACAGCGGAG GTCATCCTTC 
AGTAGTCAGT TTCAGCTTTC AGCTCAGTTA GGAGCCATGC AGCATCTCAA AGACCAGCTA 
GAGCAGCGGA CACGCATGAT AGAAGCAAAT ATTCATCGGC AGCAAGAAGA ACTAAGGAAA 
ATTCAAGAAC AACTTCAAAT GGTCCATGGT CAAGGGCTAC AGATGTTTTT GCAGCAATCA 
AACCCTGGAC TGAATCTTGG TTCTGTTCAA CTTTCCTCTG GAAATTCCAA TATCCAGCAA 
CTCACACCTA TAAATATGCA AGGCCAAGTT GTCCCTGTTA ACCAGATTCA GAGTGGGGTG 
AATGCTGGCC ATGTCAGCAC AGGCCAGCAC ATGATCCAGC AGCAGACTTT ACAAAGTACA 
TCAACTCAGA GTCAACAGAG TGTAATGAGT GGACACAGTC AGCCAACGTC TCTTCCAAAC 
CAGACGCCGA GCACTCTGAC AGCCCCACTG TACAATACGA TGGTGATCTC TCAGCCTGCG 
GCTGGGAGCA TGGTCCCGAT TCCATCCAGT ATGCCGCAGA ATAGCACCCA GAGTGCTACA 
GTCACCACGT TCACTCAGGA CAGACAGATA AGGTTTTCTC AAGGTCAGCA ACTTGTGACC 
AAATTAGTGA CTGCTCCTGT AGCTTGTGGG GCCGTCATGG TGCCAAGTAC CATGCTTATG 
GGTCAGGTAG TGACTGCCTA TCCTACTTTT GCCACACAAC AGCAGCAGGC ACAGGCCTTG 
TCAGTAACAC AGCAACAGCA GCAGCAGCAG CAGCAGCAGC AACAGCAGCA GCAGCAGCAG 
CCGCAGCAGG CGCAGCAGCC CCAGTCACAG CAGAGTTCCC AGGACCAGCC GCATCCTTCA 
GTTCAGCAGC CAGCTCAGCT GACCCAGCCA CCACAACAGT TCTTACAGAC ATCTCGGTTG 
CTCCATGGGA ATCCTTCGAC ACAGCTCATC CTCTCCGCTG CCTTTCCACT ACAACAGAGC 
ACTTTCCCTC CTTCGCACCA CCAGCAACAC CAGCAACAGC AGCTCCATCG GCACAGGACT 
GACAGCCTGA CTGACCCTTC CAAGGTCCAG CCACAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001276761.1
CDS	1..2499
Translation	MLFTVSCSKMSSIVDRDDSSIFDGLVEEDDKDKAKRVSRNKSEKKRRDQFNVLIKELGSMLPGNARKMDKSTVLQKSIDFLRKHKEITAQSDASEIRQDWKPTFLSNEEFTQLMLEALDGFFLAIMTDGSIIYVSETVTSLLEHLPSDLVDQSIFNFIPEGEHSEVYKILSTHLLESDSLTPEDLKSKNQLEFCCHMLRGTIDPKEPSTYEYVRFIGNFKSLNSVSTSTHNGFEGTIQRTHRPSYEDRVCFVATVRLATPQFIKEMCTVEEPNEEFTSRHSLEWKFLFLDHRAPPIIGYLPFEVLGTSGYDYYHVDDLESLAKCHEHLMQYGKGKSCYYRFLTKGQQWIWLQTHYYITYHQWNSRPEFIVCTHTVVSYAEVRAERRRELGVEESLPETAADKSQDSGSDNRINTVSLKEALERFDHSPTPSASSRSSRKSSHTAVSDPSSTPTKIPTDTSTPPRPHLPAHEKMTQRRSSFSSQFQLSAQLGAMQHLKDQLEQRTRMIEANIHRQQEELRKIQEQLQMVHGQGLQMFLQQSNPGLNLGSVQLSSGNSNIQQLTPINMQGQVVPVNQIQSGVNAGHVSTGQHMIQQQTLQSTSTQSQQSVMSGHSQPTSLPNQTPSTLTAPLYNTMVISQPAAGSMVPIPSSMPQNSTQSATVTTFTQDRQIRFSQGQQLVTKLVTAPVACGAVMVPSTMLMGQVVTAYPTFATQQQQAQALSVTQQQQQQQQQQQQQQQQQPQQAQQPQSQQSSQDQPHPSVQQPAQLTQPPQQFLQTSRLLHGNPSTQLILSAAFPLQQSTFPPSHHQQHQQQQLHRHRTDSLTDPSKVQPQ

Target ORF information:

RefSeq Version	NM_001289832.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus clock circadian regulator (Clock), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001289832.1

ORF Insert Sequence:

ATGTTGTTTA CCGTAAGCTG TAGTAAAATG AGCTCAATTG TTGACAGAGA TGACAGTAGT 
ATTTTTGATG GATTGGTGGA AGAAGATGAC AAGGACAAAG CAAAAAGAGT ATCTAGAAAC 
AAATCAGAAA AGAAACGTAG AGATCAGTTC AATGTACTCA TTAAGGAACT GGGGTCTATG 
CTTCCTGGTA ATGCTAGAAA GATGGACAAG TCTACTGTTC TACAGAAGAG CATTGATTTT 
TTACGCAAAC ATAAAGAGAT CACTGCACAG TCAGATGCTA GTGAAATTCG ACAGGACTGG 
AAACCTACAT TCCTTAGTAA TGAAGAGTTT ACACAATTAA TGTTAGAGGC TCTTGATGGT 
TTTTTTTTAG CGATCATGAC AGATGGAAGT ATAATATATG TATCTGAGAC GGTAACTTCG 
TTACTTGAAC ATTTACCATC TGATCTTGTG GATCAAAGTA TATTTAATTT TATCCCAGAG 
GGAGAACATT CAGAGGTTTA TAAGATACTA TCTACTCACC TGCTGGAAAG TGACTCCTTA 
ACCCCCGAGG ACTTAAAATC AAAAAATCAG TTAGAATTCT GTTGTCACAT GCTTCGAGGA 
ACAATAGACC CAAAGGAGCC ATCCACCTAT GAATATGTGA GATTTATAGG AAATTTTAAA 
TCTTTAAACA GTGTATCAAC TTCAACACAT AATGGTTTCG AAGGAACTAT ACAGCGCACA 
CACAGGCCTT CTTATGAAGA TAGAGTTTGT TTCGTAGCTA CTGTCAGATT AGCTACCCCT 
CAGTTCATCA AGGAAATGTG TACTGTTGAA GAACCGAATG AAGAGTTCAC ATCTAGACAC 
AGTTTAGAAT GGAAGTTTCT ATTTCTAGAT CACAGGGCGC CGCCAATCAT AGGCTATCTG 
CCGTTTGAAG TCCTGGGAAC ATCAGGCTAT GATTACTATC ATGTGGACGA CCTAGAAAGT 
CTGGCAAAAT GTCATGAGCA CTTAATGCAA TATGGAAAAG GCAAATCATG TTACTATAGG 
TTCTTGACCA AAGGACAGCA GTGGATTTGG CTTCAGACTC ATTACTATAT CACTTACCAT 
CAGTGGAACT CAAGGCCAGA GTTCATCGTT TGTACTCACA CTGTAGTAAG TTATGCAGAA 
GTTAGGGCTG AAAGACGGCG AGAACTTGGC GTTGAGGAGT CTCTTCCCGA GACAGCTGCT 
GACAAAAGCC AAGATTCTGG GTCTGACAAT CGTATAAACA CAGTGAGTCT CAAGGAAGCA 
CTGGAAAGGT TCGATCACAG CCCAACTCCT TCTGCCTCCT CCAGAAGCTC AAGAAAGTCC 
TCGCACACAG CAGTCTCAGA CCCTTCCTCA ACGCCGACAA AGATCCCCAC TGATACTAGC 
ACTCCTCCCA GACCGCACCT GCCAGCTCAT GAGAAGATGA CACAGCGGAG GTCATCCTTC 
AGTAGTCAGT TTCAGCTTTC AGCTCAGTTA GGAGCCATGC AGCATCTCAA AGACCAGCTA 
GAGCAGCGGA CACGCATGAT AGAAGCAAAT ATTCATCGGC AGCAAGAAGA ACTAAGGAAA 
ATTCAAGAAC AACTTCAAAT GGTCCATGGT CAAGGGCTAC AGATGTTTTT GCAGCAATCA 
AACCCTGGAC TGAATCTTGG TTCTGTTCAA CTTTCCTCTG GAAATTCCAA TATCCAGCAA 
CTCACACCTA TAAATATGCA AGGCCAAGTT GTCCCTGTTA ACCAGATTCA GAGTGGGGTG 
AATGCTGGCC ATGTCAGCAC AGGCCAGCAC ATGATCCAGC AGCAGACTTT ACAAAGTACA 
TCAACTCAGA GTCAACAGAG TGTAATGAGT GGACACAGTC AGCCAACGTC TCTTCCAAAC 
CAGACGCCGA GCACTCTGAC AGCCCCACTG TACAATACGA TGGTGATCTC TCAGCCTGCG 
GCTGGGAGCA TGGTCCCGAT TCCATCCAGT ATGCCGCAGA ATAGCACCCA GAGTGCTACA 
GTCACCACGT TCACTCAGGA CAGACAGATA AGGTTTTCTC AAGGTCAGCA ACTTGTGACC 
AAATTAGTGA CTGCTCCTGT AGCTTGTGGG GCCGTCATGG TGCCAAGTAC CATGCTTATG 
GGTCAGGTAG TGACTGCCTA TCCTACTTTT GCCACACAAC AGCAGCAGGC ACAGGCCTTG 
TCAGTAACAC AGCAACAGCA GCAGCAGCAG CAGCAGCAGC AACAGCAGCA GCAGCAGCAG 
CCGCAGCAGG CGCAGCAGCC CCAGTCACAG CAGAGTTCCC AGGACCAGCC GCATCCTTCA 
GTTCAGCAGC CAGCTCAGCT GACCCAGCCA CCACAACAGT TCTTACAGAC ATCTCGGTTG 
CTCCATGGGA ATCCTTCGAC ACAGCTCATC CTCTCCGCTG CCTTTCCACT ACAACAGAGC 
ACTTTCCCTC CTTCGCACCA CCAGCAACAC CAGCAACAGC AGCTCCATCG GCACAGGACT 
GACAGCCTGA CTGACCCTTC CAAGGTCCAG CCACAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Clock ( NM_021856.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_068628.1 Rattus norvegicus clock circadian regulator (Clock), transcript variant 1, mRNA.

Price & Availability↑

CloneID	ORa12956
Clone ID Related Accession (Same CDS sequence)	NM_021856.2
Accession Version	NM_021856.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2589bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-23
Organism	Rattus norvegicus(Norway rat)
Product	circadian locomoter output cycles protein kaput isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AB019258.1 and AC116236.5. On Jan 31, 2014 this sequence version replaced NM_021856.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB019258.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTTGTTTA CCGTAAGCTG TAGTAAAATG AGCTCAATTG TTGACAGAGA TGACAGTAGT 
ATTTTTGATG GATTGGTGGA AGAAGATGAC AAGGACAAAG CAAAAAGAGT ATCTAGAAAC 
AAATCAGAAA AGAAACGTAG AGATCAGTTC AATGTACTCA TTAAGGAACT GGGGTCTATG 
CTTCCTGGTA ATGCTAGAAA GATGGACAAG TCTACTGTTC TACAGAAGAG CATTGATTTT 
TTACGCAAAC ATAAAGAGAT CACTGCACAG TCAGATGCTA GTGAAATTCG ACAGGACTGG 
AAACCTACAT TCCTTAGTAA TGAAGAGTTT ACACAATTAA TGTTAGAGGC TCTTGATGGT 
TTTTTTTTAG CGATCATGAC AGATGGAAGT ATAATATATG TATCTGAGAC GGTAACTTCG 
TTACTTGAAC ATTTACCATC TGATCTTGTG GATCAAAGTA TATTTAATTT TATCCCAGAG 
GGAGAACATT CAGAGGTTTA TAAGATACTA TCTACTCACC TGCTGGAAAG TGACTCCTTA 
ACCCCCGAGG ACTTAAAATC AAAAAATCAG TTAGAATTCT GTTGTCACAT GCTTCGAGGA 
ACAATAGACC CAAAGGAGCC ATCCACCTAT GAATATGTGA GATTTATAGG AAATTTTAAA 
TCTTTAAACA GTGTATCAAC TTCAACACAT AATGGTTTCG AAGGAACTAT ACAGCGCACA 
CACAGGCCTT CTTATGAAGA TAGAGTTTGT TTCGTAGCTA CTGTCAGATT AGCTACCCCT 
CAGTTCATCA AGGAAATGTG TACTGTTGAA GAACCGAATG AAGAGTTCAC ATCTAGACAC 
AGTTTAGAAT GGAAGTTTCT ATTTCTAGAT CACAGGGCGC CGCCAATCAT AGGCTATCTG 
CCGTTTGAAG TCCTGGGAAC ATCAGGCTAT GATTACTATC ATGTGGACGA CCTAGAAAGT 
CTGGCAAAAT GTCATGAGCA CTTAATGCAA TATGGAAAAG GCAAATCATG TTACTATAGG 
TTCTTGACCA AAGGACAGCA GTGGATTTGG CTTCAGACTC ATTACTATAT CACTTACCAT 
CAGTGGAACT CAAGGCCAGA GTTCATCGTT TGTACTCACA CTGTAGTAAG TTATGCAGAA 
GTTAGGGCTG AAAGACGGCG AGAACTTGGC GTTGAGGAGT CTCTTCCCGA GACAGCTGCT 
GACAAAAGCC AAGATTCTGG GTCTGACAAT CGTATAAACA CAGTGAGTCT CAAGGAAGCA 
CTGGAAAGGT TCGATCACAG CCCAACTCCT TCTGCCTCCT CCAGAAGCTC AAGAAAGTCC 
TCGCACACAG CAGTCTCAGA CCCTTCCTCA ACGCCGACAA AGATCCCCAC TGATACTAGC 
ACTCCTCCCA GACCGCACCT GCCAGCTCAT GAGAAGATGA CACAGCGGAG GTCATCCTTC 
AGTAGTCAGT CCATAAACTC CCAGTCAGTT GGTTCATCAT TAACACAGCC AGCGATGTCT 
CAAGCTGCAA ATTTACCAAT CCCACAAGGC ATGTCACAGT TTCAGCTTTC AGCTCAGTTA 
GGAGCCATGC AGCATCTCAA AGACCAGCTA GAGCAGCGGA CACGCATGAT AGAAGCAAAT 
ATTCATCGGC AGCAAGAAGA ACTAAGGAAA ATTCAAGAAC AACTTCAAAT GGTCCATGGT 
CAAGGGCTAC AGATGTTTTT GCAGCAATCA AACCCTGGAC TGAATCTTGG TTCTGTTCAA 
CTTTCCTCTG GAAATTCCAA TATCCAGCAA CTCACACCTA TAAATATGCA AGGCCAAGTT 
GTCCCTGTTA ACCAGATTCA GAGTGGGGTG AATGCTGGCC ATGTCAGCAC AGGCCAGCAC 
ATGATCCAGC AGCAGACTTT ACAAAGTACA TCAACTCAGA GTCAACAGAG TGTAATGAGT 
GGACACAGTC AGCCAACGTC TCTTCCAAAC CAGACGCCGA GCACTCTGAC AGCCCCACTG 
TACAATACGA TGGTGATCTC TCAGCCTGCG GCTGGGAGCA TGGTCCCGAT TCCATCCAGT 
ATGCCGCAGA ATAGCACCCA GAGTGCTACA GTCACCACGT TCACTCAGGA CAGACAGATA 
AGGTTTTCTC AAGGTCAGCA ACTTGTGACC AAATTAGTGA CTGCTCCTGT AGCTTGTGGG 
GCCGTCATGG TGCCAAGTAC CATGCTTATG GGTCAGGTAG TGACTGCCTA TCCTACTTTT 
GCCACACAAC AGCAGCAGGC ACAGGCCTTG TCAGTAACAC AGCAACAGCA GCAGCAGCAG 
CAGCAGCAGC AACAGCAGCA GCAGCAGCAG CCGCAGCAGG CGCAGCAGCC CCAGTCACAG 
CAGAGTTCCC AGGACCAGCC GCATCCTTCA GTTCAGCAGC CAGCTCAGCT GACCCAGCCA 
CCACAACAGT TCTTACAGAC ATCTCGGTTG CTCCATGGGA ATCCTTCGAC ACAGCTCATC 
CTCTCCGCTG CCTTTCCACT ACAACAGAGC ACTTTCCCTC CTTCGCACCA CCAGCAACAC 
CAGCAACAGC AGCTCCATCG GCACAGGACT GACAGCCTGA CTGACCCTTC CAAGGTCCAG 
CCACAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_068628.1
CDS	1..2589
Translation	MLFTVSCSKMSSIVDRDDSSIFDGLVEEDDKDKAKRVSRNKSEKKRRDQFNVLIKELGSMLPGNARKMDKSTVLQKSIDFLRKHKEITAQSDASEIRQDWKPTFLSNEEFTQLMLEALDGFFLAIMTDGSIIYVSETVTSLLEHLPSDLVDQSIFNFIPEGEHSEVYKILSTHLLESDSLTPEDLKSKNQLEFCCHMLRGTIDPKEPSTYEYVRFIGNFKSLNSVSTSTHNGFEGTIQRTHRPSYEDRVCFVATVRLATPQFIKEMCTVEEPNEEFTSRHSLEWKFLFLDHRAPPIIGYLPFEVLGTSGYDYYHVDDLESLAKCHEHLMQYGKGKSCYYRFLTKGQQWIWLQTHYYITYHQWNSRPEFIVCTHTVVSYAEVRAERRRELGVEESLPETAADKSQDSGSDNRINTVSLKEALERFDHSPTPSASSRSSRKSSHTAVSDPSSTPTKIPTDTSTPPRPHLPAHEKMTQRRSSFSSQSINSQSVGSSLTQPAMSQAANLPIPQGMSQFQLSAQLGAMQHLKDQLEQRTRMIEANIHRQQEELRKIQEQLQMVHGQGLQMFLQQSNPGLNLGSVQLSSGNSNIQQLTPINMQGQVVPVNQIQSGVNAGHVSTGQHMIQQQTLQSTSTQSQQSVMSGHSQPTSLPNQTPSTLTAPLYNTMVISQPAAGSMVPIPSSMPQNSTQSATVTTFTQDRQIRFSQGQQLVTKLVTAPVACGAVMVPSTMLMGQVVTAYPTFATQQQQAQALSVTQQQQQQQQQQQQQQQQQPQQAQQPQSQQSSQDQPHPSVQQPAQLTQPPQQFLQTSRLLHGNPSTQLILSAAFPLQQSTFPPSHHQQHQQQQLHRHRTDSLTDPSKVQPQ

Target ORF information:

RefSeq Version	NM_021856.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus clock circadian regulator (Clock), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_021856.2

ORF Insert Sequence:

ATGTTGTTTA CCGTAAGCTG TAGTAAAATG AGCTCAATTG TTGACAGAGA TGACAGTAGT 
ATTTTTGATG GATTGGTGGA AGAAGATGAC AAGGACAAAG CAAAAAGAGT ATCTAGAAAC 
AAATCAGAAA AGAAACGTAG AGATCAGTTC AATGTACTCA TTAAGGAACT GGGGTCTATG 
CTTCCTGGTA ATGCTAGAAA GATGGACAAG TCTACTGTTC TACAGAAGAG CATTGATTTT 
TTACGCAAAC ATAAAGAGAT CACTGCACAG TCAGATGCTA GTGAAATTCG ACAGGACTGG 
AAACCTACAT TCCTTAGTAA TGAAGAGTTT ACACAATTAA TGTTAGAGGC TCTTGATGGT 
TTTTTTTTAG CGATCATGAC AGATGGAAGT ATAATATATG TATCTGAGAC GGTAACTTCG 
TTACTTGAAC ATTTACCATC TGATCTTGTG GATCAAAGTA TATTTAATTT TATCCCAGAG 
GGAGAACATT CAGAGGTTTA TAAGATACTA TCTACTCACC TGCTGGAAAG TGACTCCTTA 
ACCCCCGAGG ACTTAAAATC AAAAAATCAG TTAGAATTCT GTTGTCACAT GCTTCGAGGA 
ACAATAGACC CAAAGGAGCC ATCCACCTAT GAATATGTGA GATTTATAGG AAATTTTAAA 
TCTTTAAACA GTGTATCAAC TTCAACACAT AATGGTTTCG AAGGAACTAT ACAGCGCACA 
CACAGGCCTT CTTATGAAGA TAGAGTTTGT TTCGTAGCTA CTGTCAGATT AGCTACCCCT 
CAGTTCATCA AGGAAATGTG TACTGTTGAA GAACCGAATG AAGAGTTCAC ATCTAGACAC 
AGTTTAGAAT GGAAGTTTCT ATTTCTAGAT CACAGGGCGC CGCCAATCAT AGGCTATCTG 
CCGTTTGAAG TCCTGGGAAC ATCAGGCTAT GATTACTATC ATGTGGACGA CCTAGAAAGT 
CTGGCAAAAT GTCATGAGCA CTTAATGCAA TATGGAAAAG GCAAATCATG TTACTATAGG 
TTCTTGACCA AAGGACAGCA GTGGATTTGG CTTCAGACTC ATTACTATAT CACTTACCAT 
CAGTGGAACT CAAGGCCAGA GTTCATCGTT TGTACTCACA CTGTAGTAAG TTATGCAGAA 
GTTAGGGCTG AAAGACGGCG AGAACTTGGC GTTGAGGAGT CTCTTCCCGA GACAGCTGCT 
GACAAAAGCC AAGATTCTGG GTCTGACAAT CGTATAAACA CAGTGAGTCT CAAGGAAGCA 
CTGGAAAGGT TCGATCACAG CCCAACTCCT TCTGCCTCCT CCAGAAGCTC AAGAAAGTCC 
TCGCACACAG CAGTCTCAGA CCCTTCCTCA ACGCCGACAA AGATCCCCAC TGATACTAGC 
ACTCCTCCCA GACCGCACCT GCCAGCTCAT GAGAAGATGA CACAGCGGAG GTCATCCTTC 
AGTAGTCAGT CCATAAACTC CCAGTCAGTT GGTTCATCAT TAACACAGCC AGCGATGTCT 
CAAGCTGCAA ATTTACCAAT CCCACAAGGC ATGTCACAGT TTCAGCTTTC AGCTCAGTTA 
GGAGCCATGC AGCATCTCAA AGACCAGCTA GAGCAGCGGA CACGCATGAT AGAAGCAAAT 
ATTCATCGGC AGCAAGAAGA ACTAAGGAAA ATTCAAGAAC AACTTCAAAT GGTCCATGGT 
CAAGGGCTAC AGATGTTTTT GCAGCAATCA AACCCTGGAC TGAATCTTGG TTCTGTTCAA 
CTTTCCTCTG GAAATTCCAA TATCCAGCAA CTCACACCTA TAAATATGCA AGGCCAAGTT 
GTCCCTGTTA ACCAGATTCA GAGTGGGGTG AATGCTGGCC ATGTCAGCAC AGGCCAGCAC 
ATGATCCAGC AGCAGACTTT ACAAAGTACA TCAACTCAGA GTCAACAGAG TGTAATGAGT 
GGACACAGTC AGCCAACGTC TCTTCCAAAC CAGACGCCGA GCACTCTGAC AGCCCCACTG 
TACAATACGA TGGTGATCTC TCAGCCTGCG GCTGGGAGCA TGGTCCCGAT TCCATCCAGT 
ATGCCGCAGA ATAGCACCCA GAGTGCTACA GTCACCACGT TCACTCAGGA CAGACAGATA 
AGGTTTTCTC AAGGTCAGCA ACTTGTGACC AAATTAGTGA CTGCTCCTGT AGCTTGTGGG 
GCCGTCATGG TGCCAAGTAC CATGCTTATG GGTCAGGTAG TGACTGCCTA TCCTACTTTT 
GCCACACAAC AGCAGCAGGC ACAGGCCTTG TCAGTAACAC AGCAACAGCA GCAGCAGCAG 
CAGCAGCAGC AACAGCAGCA GCAGCAGCAG CCGCAGCAGG CGCAGCAGCC CCAGTCACAG 
CAGAGTTCCC AGGACCAGCC GCATCCTTCA GTTCAGCAGC CAGCTCAGCT GACCCAGCCA 
CCACAACAGT TCTTACAGAC ATCTCGGTTG CTCCATGGGA ATCCTTCGAC ACAGCTCATC 
CTCTCCGCTG CCTTTCCACT ACAACAGAGC ACTTTCCCTC CTTCGCACCA CCAGCAACAC 
CAGCAACAGC AGCTCCATCG GCACAGGACT GACAGCCTGA CTGACCCTTC CAAGGTCCAG 
CCACAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Clock ( XM_017599362.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017454851.1 Rattus norvegicus clock circadian regulator (Clock), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa36000
Clone ID Related Accession (Same CDS sequence)	XM_017599362.1 , XM_017599363.1 , XM_006250869.3 , XM_017599361.1 , XM_017599364.1
Accession Version	XM_017599362.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2595bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	circadian locomoter output cycles protein kaput isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005113.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTGTTTA CCGTAAGCTG TAGTAAAATG AGCTCAATTG TTGACAGAGA TGACAGTAGT 
ATTTTTGATG GATTGGTGGA AGAAGATGAC AAGGACAAAG CAAAAAGAGT ATCTAGAAAC 
AAATCAGAAA AGAAACGTAG AGATCAGTTC AATGTACTCA TTAAGGAACT GGGGTCTATG 
CTTCCTGGTA ATGCTAGAAA GATGGACAAG TCTACTGTTC TACAGAAGAG CATTGATTTT 
TTACGCAAAC ATAAAGAGAT CACTGCACAG TCAGATGCTA GTGAAATTCG ACAGGACTGG 
AAACCTACAT TCCTTAGTAA TGAAGAGTTT ACACAATTAA TGTTAGAGGC TCTTGATGGT 
TTTTTTTTAG CGATCATGAC AGATGGAAGT GTAGTATATG TATCTGAGAC GGTAACTTCG 
TTACTTGAAC ACTTACCATC TGATCTTGTG GATCAAAGTA TATTTAATTT TATCCCAGAG 
GGAGAACATT CAGAGGTTTA TAAGATACTA TCTACTCACC TGCTGGAAAG TGACTCCTTA 
ACCCCCGAGG ACTTAAAATC AAAAAATCAG TTAGAATTCT GTTGTCACAT GCTTCGAGGA 
ACAATAGACC CAAAGGAGCC ATCCACCTAT GAATATGTGA GATTTATAGG AAATTTTAAA 
TCTTTAAACA GTGTATCAAC TTCAACACAT AATGGTTTCG AAGGAACTAT ACAGCGCACA 
CACAGGCCTT CTTATGAAGA TAGAGTTTGT TTCGTAGCTA CTGTCAGATT AGCTACCCCT 
CAGTTCATCA AGGAAATGTG TACTGTTGAA GAACCGAATG AAGAGTTCAC ATCTAGACAC 
AGTTTAGAAT GGAAGTTTCT ATTTCTAGAT CACAGGGCGC CGCCAATCAT AGGCTATCTG 
CCGTTTGAAG TCCTGGGAAC ATCAGGCTAT GATTACTATC ATGTGGACGA CCTAGAAAGT 
CTGGCAAAAT GTCATGAGCA CTTAATGCAA TATGGAAAAG GCAAATCATG TTACTATAGG 
TTCTTGACCA AAGGACAGCA GTGGATTTGG CTTCAGACTC ATTACTATAT CACTTACCAT 
CAGTGGAACT CAAGGCCAGA GTTCATCGTT TGTACTCACA CTGTAGTAAG TTATGCAGAA 
GTTAGGGCTG AAAGACGGCG AGAACTTGGC ATTGAGGAGT CTCTTCCCGA GACAGCTGCT 
GACAAAAGCC AAGATTCTGG GTCTGACAAT CGTATAAACA CAGTGAGTCT CAAGGAAGCA 
CTGGAAAGGT TCGATCACAG CCCAACTCCT TCTGCCTCCT CCAGAAGCTC AAGAAAGTCC 
TCGCACACAG CAGTCTCAGA CCCTTCCTCA ACGCCGACAA AGATCCCCAC TGATACTAGC 
ACTCCTCCCA GACCGCACCT GCCAGCTCAT GAGAAGATGA CACAGCGGAG GTCATCCTTC 
AGTAGTCAGT CCATAAACTC CCAGTCAGTT GGTTCATCAT TAACACAGCC AGCGATGTCT 
CAAGCTGCAA ATTTACCAAT CCCACAAGGC ATGTCACAGT TTCAGCTTTC AGCTCAGTTA 
GGAGCCATGC AGCATCTCAA AGACCAGCTA GAGCAGCGGA CACGCATGAT AGAAGCAAAT 
ATTCATCGGC AGCAAGAAGA ACTAAGGAAA ATTCAAGAAC AACTTCAAAT GGTCCATGGT 
CAAGGGCTAC AGATGTTTTT GCAGCAATCA AACCCTGGAC TGAATTTTGG TTCTGTTCAA 
CTTTCCTCTG GAAATTCCAA TATCCAGCAA CTCACACCTA TAAATATGCA AGGCCAAGTT 
GTCCCTGTTA ACCAGATTCA GAGTGGGGTG AATGCTGGCC ATGTCAGCAC AGGCCAGCAC 
ATGATCCAGC AGCAGACTTT ACAAAGTACA TCAACTCAGC AGAGTCAACA GAGTGTAATG 
AGTGGACACA GTCAGCCAAC GTCTCTTCCA AACCAGACGC CGAGCACTCT GACAGCCCCA 
CTGTACAATA CGATGGTGAT CTCTCAGCCT GCAGCTGGGA GCATGGTCCC GATTCCATCC 
AGTATGCCGC AGAACAGCAC CCAGAGTGCT ACAGTCACCA CGTTCACTCA GGACAGACAG 
ATAAGGTTTT CTCAAGGTCA GCAACTTGTG ACCAAATTAG TGACTGCTCC TGTAGCTTGT 
GGGGCCGTCA TGGTGCCAAG TACCATGCTT ATGGGTCAGG TAGTGACTGC CTATCCTACC 
TTTGCCACAC AACAGCAGCA GGCACAGGCC TTGTCAGTAA CACAGCAACA GCAGCAGCAG 
CAGCAGCAGC AGCAACAGCA GCAGCAGCAG CAGCCGCAGC AGGCGCAGCC GCAGCCCCAG 
TCACAGCAGA GTTCCCAGGA CCAGCCGCAT CCTTCAGTTC AGCAGCCAGC TCAGCTGACC 
CAGCCACCAC AACAGTTCTT ACAGACATCT CGGTTGCTCC ATGGGAATCC TTCGACACAG 
CTCATCCTCT CCGCTGCCTT TCCACTACAA CAGAGCACTT TCCCTCCTTC GCACCACCAG 
CAACACCAGC AACAGCAGCT CCATCGGCAC AGGACTGACA GCCTGACTGA CCCTTCCAAG 
GTCCAGCCAC AGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017454851.1
CDS	310..2904
Translation	MLFTVSCSKMSSIVDRDDSSIFDGLVEEDDKDKAKRVSRNKSEKKRRDQFNVLIKELGSMLPGNARKMDKSTVLQKSIDFLRKHKEITAQSDASEIRQDWKPTFLSNEEFTQLMLEALDGFFLAIMTDGSVVYVSETVTSLLEHLPSDLVDQSIFNFIPEGEHSEVYKILSTHLLESDSLTPEDLKSKNQLEFCCHMLRGTIDPKEPSTYEYVRFIGNFKSLNSVSTSTHNGFEGTIQRTHRPSYEDRVCFVATVRLATPQFIKEMCTVEEPNEEFTSRHSLEWKFLFLDHRAPPIIGYLPFEVLGTSGYDYYHVDDLESLAKCHEHLMQYGKGKSCYYRFLTKGQQWIWLQTHYYITYHQWNSRPEFIVCTHTVVSYAEVRAERRRELGIEESLPETAADKSQDSGSDNRINTVSLKEALERFDHSPTPSASSRSSRKSSHTAVSDPSSTPTKIPTDTSTPPRPHLPAHEKMTQRRSSFSSQSINSQSVGSSLTQPAMSQAANLPIPQGMSQFQLSAQLGAMQHLKDQLEQRTRMIEANIHRQQEELRKIQEQLQMVHGQGLQMFLQQSNPGLNFGSVQLSSGNSNIQQLTPINMQGQVVPVNQIQSGVNAGHVSTGQHMIQQQTLQSTSTQQSQQSVMSGHSQPTSLPNQTPSTLTAPLYNTMVISQPAAGSMVPIPSSMPQNSTQSATVTTFTQDRQIRFSQGQQLVTKLVTAPVACGAVMVPSTMLMGQVVTAYPTFATQQQQAQALSVTQQQQQQQQQQQQQQQQQPQQAQPQPQSQQSSQDQPHPSVQQPAQLTQPPQQFLQTSRLLHGNPSTQLILSAAFPLQQSTFPPSHHQQHQQQQLHRHRTDSLTDPSKVQPQ

Target ORF information:

RefSeq Version	XM_017599362.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus clock circadian regulator (Clock), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017599362.1

ORF Insert Sequence:

ATGTTGTTTA CCGTAAGCTG TAGTAAAATG AGCTCAATTG TTGACAGAGA TGACAGTAGT 
ATTTTTGATG GATTGGTGGA AGAAGATGAC AAGGACAAAG CAAAAAGAGT ATCTAGAAAC 
AAATCAGAAA AGAAACGTAG AGATCAGTTC AATGTACTCA TTAAGGAACT GGGGTCTATG 
CTTCCTGGTA ATGCTAGAAA GATGGACAAG TCTACTGTTC TACAGAAGAG CATTGATTTT 
TTACGCAAAC ATAAAGAGAT CACTGCACAG TCAGATGCTA GTGAAATTCG ACAGGACTGG 
AAACCTACAT TCCTTAGTAA TGAAGAGTTT ACACAATTAA TGTTAGAGGC TCTTGATGGT 
TTTTTTTTAG CGATCATGAC AGATGGAAGT GTAGTATATG TATCTGAGAC GGTAACTTCG 
TTACTTGAAC ACTTACCATC TGATCTTGTG GATCAAAGTA TATTTAATTT TATCCCAGAG 
GGAGAACATT CAGAGGTTTA TAAGATACTA TCTACTCACC TGCTGGAAAG TGACTCCTTA 
ACCCCCGAGG ACTTAAAATC AAAAAATCAG TTAGAATTCT GTTGTCACAT GCTTCGAGGA 
ACAATAGACC CAAAGGAGCC ATCCACCTAT GAATATGTGA GATTTATAGG AAATTTTAAA 
TCTTTAAACA GTGTATCAAC TTCAACACAT AATGGTTTCG AAGGAACTAT ACAGCGCACA 
CACAGGCCTT CTTATGAAGA TAGAGTTTGT TTCGTAGCTA CTGTCAGATT AGCTACCCCT 
CAGTTCATCA AGGAAATGTG TACTGTTGAA GAACCGAATG AAGAGTTCAC ATCTAGACAC 
AGTTTAGAAT GGAAGTTTCT ATTTCTAGAT CACAGGGCGC CGCCAATCAT AGGCTATCTG 
CCGTTTGAAG TCCTGGGAAC ATCAGGCTAT GATTACTATC ATGTGGACGA CCTAGAAAGT 
CTGGCAAAAT GTCATGAGCA CTTAATGCAA TATGGAAAAG GCAAATCATG TTACTATAGG 
TTCTTGACCA AAGGACAGCA GTGGATTTGG CTTCAGACTC ATTACTATAT CACTTACCAT 
CAGTGGAACT CAAGGCCAGA GTTCATCGTT TGTACTCACA CTGTAGTAAG TTATGCAGAA 
GTTAGGGCTG AAAGACGGCG AGAACTTGGC ATTGAGGAGT CTCTTCCCGA GACAGCTGCT 
GACAAAAGCC AAGATTCTGG GTCTGACAAT CGTATAAACA CAGTGAGTCT CAAGGAAGCA 
CTGGAAAGGT TCGATCACAG CCCAACTCCT TCTGCCTCCT CCAGAAGCTC AAGAAAGTCC 
TCGCACACAG CAGTCTCAGA CCCTTCCTCA ACGCCGACAA AGATCCCCAC TGATACTAGC 
ACTCCTCCCA GACCGCACCT GCCAGCTCAT GAGAAGATGA CACAGCGGAG GTCATCCTTC 
AGTAGTCAGT CCATAAACTC CCAGTCAGTT GGTTCATCAT TAACACAGCC AGCGATGTCT 
CAAGCTGCAA ATTTACCAAT CCCACAAGGC ATGTCACAGT TTCAGCTTTC AGCTCAGTTA 
GGAGCCATGC AGCATCTCAA AGACCAGCTA GAGCAGCGGA CACGCATGAT AGAAGCAAAT 
ATTCATCGGC AGCAAGAAGA ACTAAGGAAA ATTCAAGAAC AACTTCAAAT GGTCCATGGT 
CAAGGGCTAC AGATGTTTTT GCAGCAATCA AACCCTGGAC TGAATTTTGG TTCTGTTCAA 
CTTTCCTCTG GAAATTCCAA TATCCAGCAA CTCACACCTA TAAATATGCA AGGCCAAGTT 
GTCCCTGTTA ACCAGATTCA GAGTGGGGTG AATGCTGGCC ATGTCAGCAC AGGCCAGCAC 
ATGATCCAGC AGCAGACTTT ACAAAGTACA TCAACTCAGC AGAGTCAACA GAGTGTAATG 
AGTGGACACA GTCAGCCAAC GTCTCTTCCA AACCAGACGC CGAGCACTCT GACAGCCCCA 
CTGTACAATA CGATGGTGAT CTCTCAGCCT GCAGCTGGGA GCATGGTCCC GATTCCATCC 
AGTATGCCGC AGAACAGCAC CCAGAGTGCT ACAGTCACCA CGTTCACTCA GGACAGACAG 
ATAAGGTTTT CTCAAGGTCA GCAACTTGTG ACCAAATTAG TGACTGCTCC TGTAGCTTGT 
GGGGCCGTCA TGGTGCCAAG TACCATGCTT ATGGGTCAGG TAGTGACTGC CTATCCTACC 
TTTGCCACAC AACAGCAGCA GGCACAGGCC TTGTCAGTAA CACAGCAACA GCAGCAGCAG 
CAGCAGCAGC AGCAACAGCA GCAGCAGCAG CAGCCGCAGC AGGCGCAGCC GCAGCCCCAG 
TCACAGCAGA GTTCCCAGGA CCAGCCGCAT CCTTCAGTTC AGCAGCCAGC TCAGCTGACC 
CAGCCACCAC AACAGTTCTT ACAGACATCT CGGTTGCTCC ATGGGAATCC TTCGACACAG 
CTCATCCTCT CCGCTGCCTT TCCACTACAA CAGAGCACTT TCCCTCCTTC GCACCACCAG 
CAACACCAGC AACAGCAGCT CCATCGGCAC AGGACTGACA GCCTGACTGA CCCTTCCAAG 
GTCCAGCCAC AGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Clock ( XM_017599363.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017454852.1 Rattus norvegicus clock circadian regulator (Clock), transcript variant X4, mRNA.

Price & Availability↑

CloneID	ORa36000
Clone ID Related Accession (Same CDS sequence)	XM_017599362.1 , XM_017599363.1 , XM_006250869.3 , XM_017599361.1 , XM_017599364.1
Accession Version	XM_017599363.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2595bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	circadian locomoter output cycles protein kaput isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005113.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTGTTTA CCGTAAGCTG TAGTAAAATG AGCTCAATTG TTGACAGAGA TGACAGTAGT 
ATTTTTGATG GATTGGTGGA AGAAGATGAC AAGGACAAAG CAAAAAGAGT ATCTAGAAAC 
AAATCAGAAA AGAAACGTAG AGATCAGTTC AATGTACTCA TTAAGGAACT GGGGTCTATG 
CTTCCTGGTA ATGCTAGAAA GATGGACAAG TCTACTGTTC TACAGAAGAG CATTGATTTT 
TTACGCAAAC ATAAAGAGAT CACTGCACAG TCAGATGCTA GTGAAATTCG ACAGGACTGG 
AAACCTACAT TCCTTAGTAA TGAAGAGTTT ACACAATTAA TGTTAGAGGC TCTTGATGGT 
TTTTTTTTAG CGATCATGAC AGATGGAAGT GTAGTATATG TATCTGAGAC GGTAACTTCG 
TTACTTGAAC ACTTACCATC TGATCTTGTG GATCAAAGTA TATTTAATTT TATCCCAGAG 
GGAGAACATT CAGAGGTTTA TAAGATACTA TCTACTCACC TGCTGGAAAG TGACTCCTTA 
ACCCCCGAGG ACTTAAAATC AAAAAATCAG TTAGAATTCT GTTGTCACAT GCTTCGAGGA 
ACAATAGACC CAAAGGAGCC ATCCACCTAT GAATATGTGA GATTTATAGG AAATTTTAAA 
TCTTTAAACA GTGTATCAAC TTCAACACAT AATGGTTTCG AAGGAACTAT ACAGCGCACA 
CACAGGCCTT CTTATGAAGA TAGAGTTTGT TTCGTAGCTA CTGTCAGATT AGCTACCCCT 
CAGTTCATCA AGGAAATGTG TACTGTTGAA GAACCGAATG AAGAGTTCAC ATCTAGACAC 
AGTTTAGAAT GGAAGTTTCT ATTTCTAGAT CACAGGGCGC CGCCAATCAT AGGCTATCTG 
CCGTTTGAAG TCCTGGGAAC ATCAGGCTAT GATTACTATC ATGTGGACGA CCTAGAAAGT 
CTGGCAAAAT GTCATGAGCA CTTAATGCAA TATGGAAAAG GCAAATCATG TTACTATAGG 
TTCTTGACCA AAGGACAGCA GTGGATTTGG CTTCAGACTC ATTACTATAT CACTTACCAT 
CAGTGGAACT CAAGGCCAGA GTTCATCGTT TGTACTCACA CTGTAGTAAG TTATGCAGAA 
GTTAGGGCTG AAAGACGGCG AGAACTTGGC ATTGAGGAGT CTCTTCCCGA GACAGCTGCT 
GACAAAAGCC AAGATTCTGG GTCTGACAAT CGTATAAACA CAGTGAGTCT CAAGGAAGCA 
CTGGAAAGGT TCGATCACAG CCCAACTCCT TCTGCCTCCT CCAGAAGCTC AAGAAAGTCC 
TCGCACACAG CAGTCTCAGA CCCTTCCTCA ACGCCGACAA AGATCCCCAC TGATACTAGC 
ACTCCTCCCA GACCGCACCT GCCAGCTCAT GAGAAGATGA CACAGCGGAG GTCATCCTTC 
AGTAGTCAGT CCATAAACTC CCAGTCAGTT GGTTCATCAT TAACACAGCC AGCGATGTCT 
CAAGCTGCAA ATTTACCAAT CCCACAAGGC ATGTCACAGT TTCAGCTTTC AGCTCAGTTA 
GGAGCCATGC AGCATCTCAA AGACCAGCTA GAGCAGCGGA CACGCATGAT AGAAGCAAAT 
ATTCATCGGC AGCAAGAAGA ACTAAGGAAA ATTCAAGAAC AACTTCAAAT GGTCCATGGT 
CAAGGGCTAC AGATGTTTTT GCAGCAATCA AACCCTGGAC TGAATTTTGG TTCTGTTCAA 
CTTTCCTCTG GAAATTCCAA TATCCAGCAA CTCACACCTA TAAATATGCA AGGCCAAGTT 
GTCCCTGTTA ACCAGATTCA GAGTGGGGTG AATGCTGGCC ATGTCAGCAC AGGCCAGCAC 
ATGATCCAGC AGCAGACTTT ACAAAGTACA TCAACTCAGC AGAGTCAACA GAGTGTAATG 
AGTGGACACA GTCAGCCAAC GTCTCTTCCA AACCAGACGC CGAGCACTCT GACAGCCCCA 
CTGTACAATA CGATGGTGAT CTCTCAGCCT GCAGCTGGGA GCATGGTCCC GATTCCATCC 
AGTATGCCGC AGAACAGCAC CCAGAGTGCT ACAGTCACCA CGTTCACTCA GGACAGACAG 
ATAAGGTTTT CTCAAGGTCA GCAACTTGTG ACCAAATTAG TGACTGCTCC TGTAGCTTGT 
GGGGCCGTCA TGGTGCCAAG TACCATGCTT ATGGGTCAGG TAGTGACTGC CTATCCTACC 
TTTGCCACAC AACAGCAGCA GGCACAGGCC TTGTCAGTAA CACAGCAACA GCAGCAGCAG 
CAGCAGCAGC AGCAACAGCA GCAGCAGCAG CAGCCGCAGC AGGCGCAGCC GCAGCCCCAG 
TCACAGCAGA GTTCCCAGGA CCAGCCGCAT CCTTCAGTTC AGCAGCCAGC TCAGCTGACC 
CAGCCACCAC AACAGTTCTT ACAGACATCT CGGTTGCTCC ATGGGAATCC TTCGACACAG 
CTCATCCTCT CCGCTGCCTT TCCACTACAA CAGAGCACTT TCCCTCCTTC GCACCACCAG 
CAACACCAGC AACAGCAGCT CCATCGGCAC AGGACTGACA GCCTGACTGA CCCTTCCAAG 
GTCCAGCCAC AGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017454852.1
CDS	559..3153
Translation	MLFTVSCSKMSSIVDRDDSSIFDGLVEEDDKDKAKRVSRNKSEKKRRDQFNVLIKELGSMLPGNARKMDKSTVLQKSIDFLRKHKEITAQSDASEIRQDWKPTFLSNEEFTQLMLEALDGFFLAIMTDGSVVYVSETVTSLLEHLPSDLVDQSIFNFIPEGEHSEVYKILSTHLLESDSLTPEDLKSKNQLEFCCHMLRGTIDPKEPSTYEYVRFIGNFKSLNSVSTSTHNGFEGTIQRTHRPSYEDRVCFVATVRLATPQFIKEMCTVEEPNEEFTSRHSLEWKFLFLDHRAPPIIGYLPFEVLGTSGYDYYHVDDLESLAKCHEHLMQYGKGKSCYYRFLTKGQQWIWLQTHYYITYHQWNSRPEFIVCTHTVVSYAEVRAERRRELGIEESLPETAADKSQDSGSDNRINTVSLKEALERFDHSPTPSASSRSSRKSSHTAVSDPSSTPTKIPTDTSTPPRPHLPAHEKMTQRRSSFSSQSINSQSVGSSLTQPAMSQAANLPIPQGMSQFQLSAQLGAMQHLKDQLEQRTRMIEANIHRQQEELRKIQEQLQMVHGQGLQMFLQQSNPGLNFGSVQLSSGNSNIQQLTPINMQGQVVPVNQIQSGVNAGHVSTGQHMIQQQTLQSTSTQQSQQSVMSGHSQPTSLPNQTPSTLTAPLYNTMVISQPAAGSMVPIPSSMPQNSTQSATVTTFTQDRQIRFSQGQQLVTKLVTAPVACGAVMVPSTMLMGQVVTAYPTFATQQQQAQALSVTQQQQQQQQQQQQQQQQQPQQAQPQPQSQQSSQDQPHPSVQQPAQLTQPPQQFLQTSRLLHGNPSTQLILSAAFPLQQSTFPPSHHQQHQQQQLHRHRTDSLTDPSKVQPQ

Target ORF information:

RefSeq Version	XM_017599363.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus clock circadian regulator (Clock), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017599363.1

ORF Insert Sequence:

ATGTTGTTTA CCGTAAGCTG TAGTAAAATG AGCTCAATTG TTGACAGAGA TGACAGTAGT 
ATTTTTGATG GATTGGTGGA AGAAGATGAC AAGGACAAAG CAAAAAGAGT ATCTAGAAAC 
AAATCAGAAA AGAAACGTAG AGATCAGTTC AATGTACTCA TTAAGGAACT GGGGTCTATG 
CTTCCTGGTA ATGCTAGAAA GATGGACAAG TCTACTGTTC TACAGAAGAG CATTGATTTT 
TTACGCAAAC ATAAAGAGAT CACTGCACAG TCAGATGCTA GTGAAATTCG ACAGGACTGG 
AAACCTACAT TCCTTAGTAA TGAAGAGTTT ACACAATTAA TGTTAGAGGC TCTTGATGGT 
TTTTTTTTAG CGATCATGAC AGATGGAAGT GTAGTATATG TATCTGAGAC GGTAACTTCG 
TTACTTGAAC ACTTACCATC TGATCTTGTG GATCAAAGTA TATTTAATTT TATCCCAGAG 
GGAGAACATT CAGAGGTTTA TAAGATACTA TCTACTCACC TGCTGGAAAG TGACTCCTTA 
ACCCCCGAGG ACTTAAAATC AAAAAATCAG TTAGAATTCT GTTGTCACAT GCTTCGAGGA 
ACAATAGACC CAAAGGAGCC ATCCACCTAT GAATATGTGA GATTTATAGG AAATTTTAAA 
TCTTTAAACA GTGTATCAAC TTCAACACAT AATGGTTTCG AAGGAACTAT ACAGCGCACA 
CACAGGCCTT CTTATGAAGA TAGAGTTTGT TTCGTAGCTA CTGTCAGATT AGCTACCCCT 
CAGTTCATCA AGGAAATGTG TACTGTTGAA GAACCGAATG AAGAGTTCAC ATCTAGACAC 
AGTTTAGAAT GGAAGTTTCT ATTTCTAGAT CACAGGGCGC CGCCAATCAT AGGCTATCTG 
CCGTTTGAAG TCCTGGGAAC ATCAGGCTAT GATTACTATC ATGTGGACGA CCTAGAAAGT 
CTGGCAAAAT GTCATGAGCA CTTAATGCAA TATGGAAAAG GCAAATCATG TTACTATAGG 
TTCTTGACCA AAGGACAGCA GTGGATTTGG CTTCAGACTC ATTACTATAT CACTTACCAT 
CAGTGGAACT CAAGGCCAGA GTTCATCGTT TGTACTCACA CTGTAGTAAG TTATGCAGAA 
GTTAGGGCTG AAAGACGGCG AGAACTTGGC ATTGAGGAGT CTCTTCCCGA GACAGCTGCT 
GACAAAAGCC AAGATTCTGG GTCTGACAAT CGTATAAACA CAGTGAGTCT CAAGGAAGCA 
CTGGAAAGGT TCGATCACAG CCCAACTCCT TCTGCCTCCT CCAGAAGCTC AAGAAAGTCC 
TCGCACACAG CAGTCTCAGA CCCTTCCTCA ACGCCGACAA AGATCCCCAC TGATACTAGC 
ACTCCTCCCA GACCGCACCT GCCAGCTCAT GAGAAGATGA CACAGCGGAG GTCATCCTTC 
AGTAGTCAGT CCATAAACTC CCAGTCAGTT GGTTCATCAT TAACACAGCC AGCGATGTCT 
CAAGCTGCAA ATTTACCAAT CCCACAAGGC ATGTCACAGT TTCAGCTTTC AGCTCAGTTA 
GGAGCCATGC AGCATCTCAA AGACCAGCTA GAGCAGCGGA CACGCATGAT AGAAGCAAAT 
ATTCATCGGC AGCAAGAAGA ACTAAGGAAA ATTCAAGAAC AACTTCAAAT GGTCCATGGT 
CAAGGGCTAC AGATGTTTTT GCAGCAATCA AACCCTGGAC TGAATTTTGG TTCTGTTCAA 
CTTTCCTCTG GAAATTCCAA TATCCAGCAA CTCACACCTA TAAATATGCA AGGCCAAGTT 
GTCCCTGTTA ACCAGATTCA GAGTGGGGTG AATGCTGGCC ATGTCAGCAC AGGCCAGCAC 
ATGATCCAGC AGCAGACTTT ACAAAGTACA TCAACTCAGC AGAGTCAACA GAGTGTAATG 
AGTGGACACA GTCAGCCAAC GTCTCTTCCA AACCAGACGC CGAGCACTCT GACAGCCCCA 
CTGTACAATA CGATGGTGAT CTCTCAGCCT GCAGCTGGGA GCATGGTCCC GATTCCATCC 
AGTATGCCGC AGAACAGCAC CCAGAGTGCT ACAGTCACCA CGTTCACTCA GGACAGACAG 
ATAAGGTTTT CTCAAGGTCA GCAACTTGTG ACCAAATTAG TGACTGCTCC TGTAGCTTGT 
GGGGCCGTCA TGGTGCCAAG TACCATGCTT ATGGGTCAGG TAGTGACTGC CTATCCTACC 
TTTGCCACAC AACAGCAGCA GGCACAGGCC TTGTCAGTAA CACAGCAACA GCAGCAGCAG 
CAGCAGCAGC AGCAACAGCA GCAGCAGCAG CAGCCGCAGC AGGCGCAGCC GCAGCCCCAG 
TCACAGCAGA GTTCCCAGGA CCAGCCGCAT CCTTCAGTTC AGCAGCCAGC TCAGCTGACC 
CAGCCACCAC AACAGTTCTT ACAGACATCT CGGTTGCTCC ATGGGAATCC TTCGACACAG 
CTCATCCTCT CCGCTGCCTT TCCACTACAA CAGAGCACTT TCCCTCCTTC GCACCACCAG 
CAACACCAGC AACAGCAGCT CCATCGGCAC AGGACTGACA GCCTGACTGA CCCTTCCAAG 
GTCCAGCCAC AGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Clock ( XM_006250869.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006250931.1 Rattus norvegicus clock circadian regulator (Clock), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa36000
Clone ID Related Accession (Same CDS sequence)	XM_017599362.1 , XM_017599363.1 , XM_006250869.3 , XM_017599361.1 , XM_017599364.1
Accession Version	XM_006250869.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2595bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	circadian locomoter output cycles protein kaput isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005113.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006250869.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTGTTTA CCGTAAGCTG TAGTAAAATG AGCTCAATTG TTGACAGAGA TGACAGTAGT 
ATTTTTGATG GATTGGTGGA AGAAGATGAC AAGGACAAAG CAAAAAGAGT ATCTAGAAAC 
AAATCAGAAA AGAAACGTAG AGATCAGTTC AATGTACTCA TTAAGGAACT GGGGTCTATG 
CTTCCTGGTA ATGCTAGAAA GATGGACAAG TCTACTGTTC TACAGAAGAG CATTGATTTT 
TTACGCAAAC ATAAAGAGAT CACTGCACAG TCAGATGCTA GTGAAATTCG ACAGGACTGG 
AAACCTACAT TCCTTAGTAA TGAAGAGTTT ACACAATTAA TGTTAGAGGC TCTTGATGGT 
TTTTTTTTAG CGATCATGAC AGATGGAAGT GTAGTATATG TATCTGAGAC GGTAACTTCG 
TTACTTGAAC ACTTACCATC TGATCTTGTG GATCAAAGTA TATTTAATTT TATCCCAGAG 
GGAGAACATT CAGAGGTTTA TAAGATACTA TCTACTCACC TGCTGGAAAG TGACTCCTTA 
ACCCCCGAGG ACTTAAAATC AAAAAATCAG TTAGAATTCT GTTGTCACAT GCTTCGAGGA 
ACAATAGACC CAAAGGAGCC ATCCACCTAT GAATATGTGA GATTTATAGG AAATTTTAAA 
TCTTTAAACA GTGTATCAAC TTCAACACAT AATGGTTTCG AAGGAACTAT ACAGCGCACA 
CACAGGCCTT CTTATGAAGA TAGAGTTTGT TTCGTAGCTA CTGTCAGATT AGCTACCCCT 
CAGTTCATCA AGGAAATGTG TACTGTTGAA GAACCGAATG AAGAGTTCAC ATCTAGACAC 
AGTTTAGAAT GGAAGTTTCT ATTTCTAGAT CACAGGGCGC CGCCAATCAT AGGCTATCTG 
CCGTTTGAAG TCCTGGGAAC ATCAGGCTAT GATTACTATC ATGTGGACGA CCTAGAAAGT 
CTGGCAAAAT GTCATGAGCA CTTAATGCAA TATGGAAAAG GCAAATCATG TTACTATAGG 
TTCTTGACCA AAGGACAGCA GTGGATTTGG CTTCAGACTC ATTACTATAT CACTTACCAT 
CAGTGGAACT CAAGGCCAGA GTTCATCGTT TGTACTCACA CTGTAGTAAG TTATGCAGAA 
GTTAGGGCTG AAAGACGGCG AGAACTTGGC ATTGAGGAGT CTCTTCCCGA GACAGCTGCT 
GACAAAAGCC AAGATTCTGG GTCTGACAAT CGTATAAACA CAGTGAGTCT CAAGGAAGCA 
CTGGAAAGGT TCGATCACAG CCCAACTCCT TCTGCCTCCT CCAGAAGCTC AAGAAAGTCC 
TCGCACACAG CAGTCTCAGA CCCTTCCTCA ACGCCGACAA AGATCCCCAC TGATACTAGC 
ACTCCTCCCA GACCGCACCT GCCAGCTCAT GAGAAGATGA CACAGCGGAG GTCATCCTTC 
AGTAGTCAGT CCATAAACTC CCAGTCAGTT GGTTCATCAT TAACACAGCC AGCGATGTCT 
CAAGCTGCAA ATTTACCAAT CCCACAAGGC ATGTCACAGT TTCAGCTTTC AGCTCAGTTA 
GGAGCCATGC AGCATCTCAA AGACCAGCTA GAGCAGCGGA CACGCATGAT AGAAGCAAAT 
ATTCATCGGC AGCAAGAAGA ACTAAGGAAA ATTCAAGAAC AACTTCAAAT GGTCCATGGT 
CAAGGGCTAC AGATGTTTTT GCAGCAATCA AACCCTGGAC TGAATTTTGG TTCTGTTCAA 
CTTTCCTCTG GAAATTCCAA TATCCAGCAA CTCACACCTA TAAATATGCA AGGCCAAGTT 
GTCCCTGTTA ACCAGATTCA GAGTGGGGTG AATGCTGGCC ATGTCAGCAC AGGCCAGCAC 
ATGATCCAGC AGCAGACTTT ACAAAGTACA TCAACTCAGC AGAGTCAACA GAGTGTAATG 
AGTGGACACA GTCAGCCAAC GTCTCTTCCA AACCAGACGC CGAGCACTCT GACAGCCCCA 
CTGTACAATA CGATGGTGAT CTCTCAGCCT GCAGCTGGGA GCATGGTCCC GATTCCATCC 
AGTATGCCGC AGAACAGCAC CCAGAGTGCT ACAGTCACCA CGTTCACTCA GGACAGACAG 
ATAAGGTTTT CTCAAGGTCA GCAACTTGTG ACCAAATTAG TGACTGCTCC TGTAGCTTGT 
GGGGCCGTCA TGGTGCCAAG TACCATGCTT ATGGGTCAGG TAGTGACTGC CTATCCTACC 
TTTGCCACAC AACAGCAGCA GGCACAGGCC TTGTCAGTAA CACAGCAACA GCAGCAGCAG 
CAGCAGCAGC AGCAACAGCA GCAGCAGCAG CAGCCGCAGC AGGCGCAGCC GCAGCCCCAG 
TCACAGCAGA GTTCCCAGGA CCAGCCGCAT CCTTCAGTTC AGCAGCCAGC TCAGCTGACC 
CAGCCACCAC AACAGTTCTT ACAGACATCT CGGTTGCTCC ATGGGAATCC TTCGACACAG 
CTCATCCTCT CCGCTGCCTT TCCACTACAA CAGAGCACTT TCCCTCCTTC GCACCACCAG 
CAACACCAGC AACAGCAGCT CCATCGGCAC AGGACTGACA GCCTGACTGA CCCTTCCAAG 
GTCCAGCCAC AGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006250931.1
CDS	277..2871
Translation	MLFTVSCSKMSSIVDRDDSSIFDGLVEEDDKDKAKRVSRNKSEKKRRDQFNVLIKELGSMLPGNARKMDKSTVLQKSIDFLRKHKEITAQSDASEIRQDWKPTFLSNEEFTQLMLEALDGFFLAIMTDGSVVYVSETVTSLLEHLPSDLVDQSIFNFIPEGEHSEVYKILSTHLLESDSLTPEDLKSKNQLEFCCHMLRGTIDPKEPSTYEYVRFIGNFKSLNSVSTSTHNGFEGTIQRTHRPSYEDRVCFVATVRLATPQFIKEMCTVEEPNEEFTSRHSLEWKFLFLDHRAPPIIGYLPFEVLGTSGYDYYHVDDLESLAKCHEHLMQYGKGKSCYYRFLTKGQQWIWLQTHYYITYHQWNSRPEFIVCTHTVVSYAEVRAERRRELGIEESLPETAADKSQDSGSDNRINTVSLKEALERFDHSPTPSASSRSSRKSSHTAVSDPSSTPTKIPTDTSTPPRPHLPAHEKMTQRRSSFSSQSINSQSVGSSLTQPAMSQAANLPIPQGMSQFQLSAQLGAMQHLKDQLEQRTRMIEANIHRQQEELRKIQEQLQMVHGQGLQMFLQQSNPGLNFGSVQLSSGNSNIQQLTPINMQGQVVPVNQIQSGVNAGHVSTGQHMIQQQTLQSTSTQQSQQSVMSGHSQPTSLPNQTPSTLTAPLYNTMVISQPAAGSMVPIPSSMPQNSTQSATVTTFTQDRQIRFSQGQQLVTKLVTAPVACGAVMVPSTMLMGQVVTAYPTFATQQQQAQALSVTQQQQQQQQQQQQQQQQQPQQAQPQPQSQQSSQDQPHPSVQQPAQLTQPPQQFLQTSRLLHGNPSTQLILSAAFPLQQSTFPPSHHQQHQQQQLHRHRTDSLTDPSKVQPQ

Target ORF information:

RefSeq Version	XM_006250869.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus clock circadian regulator (Clock), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006250869.3

ORF Insert Sequence:

ATGTTGTTTA CCGTAAGCTG TAGTAAAATG AGCTCAATTG TTGACAGAGA TGACAGTAGT 
ATTTTTGATG GATTGGTGGA AGAAGATGAC AAGGACAAAG CAAAAAGAGT ATCTAGAAAC 
AAATCAGAAA AGAAACGTAG AGATCAGTTC AATGTACTCA TTAAGGAACT GGGGTCTATG 
CTTCCTGGTA ATGCTAGAAA GATGGACAAG TCTACTGTTC TACAGAAGAG CATTGATTTT 
TTACGCAAAC ATAAAGAGAT CACTGCACAG TCAGATGCTA GTGAAATTCG ACAGGACTGG 
AAACCTACAT TCCTTAGTAA TGAAGAGTTT ACACAATTAA TGTTAGAGGC TCTTGATGGT 
TTTTTTTTAG CGATCATGAC AGATGGAAGT GTAGTATATG TATCTGAGAC GGTAACTTCG 
TTACTTGAAC ACTTACCATC TGATCTTGTG GATCAAAGTA TATTTAATTT TATCCCAGAG 
GGAGAACATT CAGAGGTTTA TAAGATACTA TCTACTCACC TGCTGGAAAG TGACTCCTTA 
ACCCCCGAGG ACTTAAAATC AAAAAATCAG TTAGAATTCT GTTGTCACAT GCTTCGAGGA 
ACAATAGACC CAAAGGAGCC ATCCACCTAT GAATATGTGA GATTTATAGG AAATTTTAAA 
TCTTTAAACA GTGTATCAAC TTCAACACAT AATGGTTTCG AAGGAACTAT ACAGCGCACA 
CACAGGCCTT CTTATGAAGA TAGAGTTTGT TTCGTAGCTA CTGTCAGATT AGCTACCCCT 
CAGTTCATCA AGGAAATGTG TACTGTTGAA GAACCGAATG AAGAGTTCAC ATCTAGACAC 
AGTTTAGAAT GGAAGTTTCT ATTTCTAGAT CACAGGGCGC CGCCAATCAT AGGCTATCTG 
CCGTTTGAAG TCCTGGGAAC ATCAGGCTAT GATTACTATC ATGTGGACGA CCTAGAAAGT 
CTGGCAAAAT GTCATGAGCA CTTAATGCAA TATGGAAAAG GCAAATCATG TTACTATAGG 
TTCTTGACCA AAGGACAGCA GTGGATTTGG CTTCAGACTC ATTACTATAT CACTTACCAT 
CAGTGGAACT CAAGGCCAGA GTTCATCGTT TGTACTCACA CTGTAGTAAG TTATGCAGAA 
GTTAGGGCTG AAAGACGGCG AGAACTTGGC ATTGAGGAGT CTCTTCCCGA GACAGCTGCT 
GACAAAAGCC AAGATTCTGG GTCTGACAAT CGTATAAACA CAGTGAGTCT CAAGGAAGCA 
CTGGAAAGGT TCGATCACAG CCCAACTCCT TCTGCCTCCT CCAGAAGCTC AAGAAAGTCC 
TCGCACACAG CAGTCTCAGA CCCTTCCTCA ACGCCGACAA AGATCCCCAC TGATACTAGC 
ACTCCTCCCA GACCGCACCT GCCAGCTCAT GAGAAGATGA CACAGCGGAG GTCATCCTTC 
AGTAGTCAGT CCATAAACTC CCAGTCAGTT GGTTCATCAT TAACACAGCC AGCGATGTCT 
CAAGCTGCAA ATTTACCAAT CCCACAAGGC ATGTCACAGT TTCAGCTTTC AGCTCAGTTA 
GGAGCCATGC AGCATCTCAA AGACCAGCTA GAGCAGCGGA CACGCATGAT AGAAGCAAAT 
ATTCATCGGC AGCAAGAAGA ACTAAGGAAA ATTCAAGAAC AACTTCAAAT GGTCCATGGT 
CAAGGGCTAC AGATGTTTTT GCAGCAATCA AACCCTGGAC TGAATTTTGG TTCTGTTCAA 
CTTTCCTCTG GAAATTCCAA TATCCAGCAA CTCACACCTA TAAATATGCA AGGCCAAGTT 
GTCCCTGTTA ACCAGATTCA GAGTGGGGTG AATGCTGGCC ATGTCAGCAC AGGCCAGCAC 
ATGATCCAGC AGCAGACTTT ACAAAGTACA TCAACTCAGC AGAGTCAACA GAGTGTAATG 
AGTGGACACA GTCAGCCAAC GTCTCTTCCA AACCAGACGC CGAGCACTCT GACAGCCCCA 
CTGTACAATA CGATGGTGAT CTCTCAGCCT GCAGCTGGGA GCATGGTCCC GATTCCATCC 
AGTATGCCGC AGAACAGCAC CCAGAGTGCT ACAGTCACCA CGTTCACTCA GGACAGACAG 
ATAAGGTTTT CTCAAGGTCA GCAACTTGTG ACCAAATTAG TGACTGCTCC TGTAGCTTGT 
GGGGCCGTCA TGGTGCCAAG TACCATGCTT ATGGGTCAGG TAGTGACTGC CTATCCTACC 
TTTGCCACAC AACAGCAGCA GGCACAGGCC TTGTCAGTAA CACAGCAACA GCAGCAGCAG 
CAGCAGCAGC AGCAACAGCA GCAGCAGCAG CAGCCGCAGC AGGCGCAGCC GCAGCCCCAG 
TCACAGCAGA GTTCCCAGGA CCAGCCGCAT CCTTCAGTTC AGCAGCCAGC TCAGCTGACC 
CAGCCACCAC AACAGTTCTT ACAGACATCT CGGTTGCTCC ATGGGAATCC TTCGACACAG 
CTCATCCTCT CCGCTGCCTT TCCACTACAA CAGAGCACTT TCCCTCCTTC GCACCACCAG 
CAACACCAGC AACAGCAGCT CCATCGGCAC AGGACTGACA GCCTGACTGA CCCTTCCAAG 
GTCCAGCCAC AGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Clock ( XM_017599361.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017454850.1 Rattus norvegicus clock circadian regulator (Clock), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa36000
Clone ID Related Accession (Same CDS sequence)	XM_017599362.1 , XM_017599363.1 , XM_006250869.3 , XM_017599361.1 , XM_017599364.1
Accession Version	XM_017599361.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2595bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	circadian locomoter output cycles protein kaput isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005113.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTGTTTA CCGTAAGCTG TAGTAAAATG AGCTCAATTG TTGACAGAGA TGACAGTAGT 
ATTTTTGATG GATTGGTGGA AGAAGATGAC AAGGACAAAG CAAAAAGAGT ATCTAGAAAC 
AAATCAGAAA AGAAACGTAG AGATCAGTTC AATGTACTCA TTAAGGAACT GGGGTCTATG 
CTTCCTGGTA ATGCTAGAAA GATGGACAAG TCTACTGTTC TACAGAAGAG CATTGATTTT 
TTACGCAAAC ATAAAGAGAT CACTGCACAG TCAGATGCTA GTGAAATTCG ACAGGACTGG 
AAACCTACAT TCCTTAGTAA TGAAGAGTTT ACACAATTAA TGTTAGAGGC TCTTGATGGT 
TTTTTTTTAG CGATCATGAC AGATGGAAGT GTAGTATATG TATCTGAGAC GGTAACTTCG 
TTACTTGAAC ACTTACCATC TGATCTTGTG GATCAAAGTA TATTTAATTT TATCCCAGAG 
GGAGAACATT CAGAGGTTTA TAAGATACTA TCTACTCACC TGCTGGAAAG TGACTCCTTA 
ACCCCCGAGG ACTTAAAATC AAAAAATCAG TTAGAATTCT GTTGTCACAT GCTTCGAGGA 
ACAATAGACC CAAAGGAGCC ATCCACCTAT GAATATGTGA GATTTATAGG AAATTTTAAA 
TCTTTAAACA GTGTATCAAC TTCAACACAT AATGGTTTCG AAGGAACTAT ACAGCGCACA 
CACAGGCCTT CTTATGAAGA TAGAGTTTGT TTCGTAGCTA CTGTCAGATT AGCTACCCCT 
CAGTTCATCA AGGAAATGTG TACTGTTGAA GAACCGAATG AAGAGTTCAC ATCTAGACAC 
AGTTTAGAAT GGAAGTTTCT ATTTCTAGAT CACAGGGCGC CGCCAATCAT AGGCTATCTG 
CCGTTTGAAG TCCTGGGAAC ATCAGGCTAT GATTACTATC ATGTGGACGA CCTAGAAAGT 
CTGGCAAAAT GTCATGAGCA CTTAATGCAA TATGGAAAAG GCAAATCATG TTACTATAGG 
TTCTTGACCA AAGGACAGCA GTGGATTTGG CTTCAGACTC ATTACTATAT CACTTACCAT 
CAGTGGAACT CAAGGCCAGA GTTCATCGTT TGTACTCACA CTGTAGTAAG TTATGCAGAA 
GTTAGGGCTG AAAGACGGCG AGAACTTGGC ATTGAGGAGT CTCTTCCCGA GACAGCTGCT 
GACAAAAGCC AAGATTCTGG GTCTGACAAT CGTATAAACA CAGTGAGTCT CAAGGAAGCA 
CTGGAAAGGT TCGATCACAG CCCAACTCCT TCTGCCTCCT CCAGAAGCTC AAGAAAGTCC 
TCGCACACAG CAGTCTCAGA CCCTTCCTCA ACGCCGACAA AGATCCCCAC TGATACTAGC 
ACTCCTCCCA GACCGCACCT GCCAGCTCAT GAGAAGATGA CACAGCGGAG GTCATCCTTC 
AGTAGTCAGT CCATAAACTC CCAGTCAGTT GGTTCATCAT TAACACAGCC AGCGATGTCT 
CAAGCTGCAA ATTTACCAAT CCCACAAGGC ATGTCACAGT TTCAGCTTTC AGCTCAGTTA 
GGAGCCATGC AGCATCTCAA AGACCAGCTA GAGCAGCGGA CACGCATGAT AGAAGCAAAT 
ATTCATCGGC AGCAAGAAGA ACTAAGGAAA ATTCAAGAAC AACTTCAAAT GGTCCATGGT 
CAAGGGCTAC AGATGTTTTT GCAGCAATCA AACCCTGGAC TGAATTTTGG TTCTGTTCAA 
CTTTCCTCTG GAAATTCCAA TATCCAGCAA CTCACACCTA TAAATATGCA AGGCCAAGTT 
GTCCCTGTTA ACCAGATTCA GAGTGGGGTG AATGCTGGCC ATGTCAGCAC AGGCCAGCAC 
ATGATCCAGC AGCAGACTTT ACAAAGTACA TCAACTCAGC AGAGTCAACA GAGTGTAATG 
AGTGGACACA GTCAGCCAAC GTCTCTTCCA AACCAGACGC CGAGCACTCT GACAGCCCCA 
CTGTACAATA CGATGGTGAT CTCTCAGCCT GCAGCTGGGA GCATGGTCCC GATTCCATCC 
AGTATGCCGC AGAACAGCAC CCAGAGTGCT ACAGTCACCA CGTTCACTCA GGACAGACAG 
ATAAGGTTTT CTCAAGGTCA GCAACTTGTG ACCAAATTAG TGACTGCTCC TGTAGCTTGT 
GGGGCCGTCA TGGTGCCAAG TACCATGCTT ATGGGTCAGG TAGTGACTGC CTATCCTACC 
TTTGCCACAC AACAGCAGCA GGCACAGGCC TTGTCAGTAA CACAGCAACA GCAGCAGCAG 
CAGCAGCAGC AGCAACAGCA GCAGCAGCAG CAGCCGCAGC AGGCGCAGCC GCAGCCCCAG 
TCACAGCAGA GTTCCCAGGA CCAGCCGCAT CCTTCAGTTC AGCAGCCAGC TCAGCTGACC 
CAGCCACCAC AACAGTTCTT ACAGACATCT CGGTTGCTCC ATGGGAATCC TTCGACACAG 
CTCATCCTCT CCGCTGCCTT TCCACTACAA CAGAGCACTT TCCCTCCTTC GCACCACCAG 
CAACACCAGC AACAGCAGCT CCATCGGCAC AGGACTGACA GCCTGACTGA CCCTTCCAAG 
GTCCAGCCAC AGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017454850.1
CDS	313..2907
Translation	MLFTVSCSKMSSIVDRDDSSIFDGLVEEDDKDKAKRVSRNKSEKKRRDQFNVLIKELGSMLPGNARKMDKSTVLQKSIDFLRKHKEITAQSDASEIRQDWKPTFLSNEEFTQLMLEALDGFFLAIMTDGSVVYVSETVTSLLEHLPSDLVDQSIFNFIPEGEHSEVYKILSTHLLESDSLTPEDLKSKNQLEFCCHMLRGTIDPKEPSTYEYVRFIGNFKSLNSVSTSTHNGFEGTIQRTHRPSYEDRVCFVATVRLATPQFIKEMCTVEEPNEEFTSRHSLEWKFLFLDHRAPPIIGYLPFEVLGTSGYDYYHVDDLESLAKCHEHLMQYGKGKSCYYRFLTKGQQWIWLQTHYYITYHQWNSRPEFIVCTHTVVSYAEVRAERRRELGIEESLPETAADKSQDSGSDNRINTVSLKEALERFDHSPTPSASSRSSRKSSHTAVSDPSSTPTKIPTDTSTPPRPHLPAHEKMTQRRSSFSSQSINSQSVGSSLTQPAMSQAANLPIPQGMSQFQLSAQLGAMQHLKDQLEQRTRMIEANIHRQQEELRKIQEQLQMVHGQGLQMFLQQSNPGLNFGSVQLSSGNSNIQQLTPINMQGQVVPVNQIQSGVNAGHVSTGQHMIQQQTLQSTSTQQSQQSVMSGHSQPTSLPNQTPSTLTAPLYNTMVISQPAAGSMVPIPSSMPQNSTQSATVTTFTQDRQIRFSQGQQLVTKLVTAPVACGAVMVPSTMLMGQVVTAYPTFATQQQQAQALSVTQQQQQQQQQQQQQQQQQPQQAQPQPQSQQSSQDQPHPSVQQPAQLTQPPQQFLQTSRLLHGNPSTQLILSAAFPLQQSTFPPSHHQQHQQQQLHRHRTDSLTDPSKVQPQ

Target ORF information:

RefSeq Version	XM_017599361.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus clock circadian regulator (Clock), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017599361.1

ORF Insert Sequence:

ATGTTGTTTA CCGTAAGCTG TAGTAAAATG AGCTCAATTG TTGACAGAGA TGACAGTAGT 
ATTTTTGATG GATTGGTGGA AGAAGATGAC AAGGACAAAG CAAAAAGAGT ATCTAGAAAC 
AAATCAGAAA AGAAACGTAG AGATCAGTTC AATGTACTCA TTAAGGAACT GGGGTCTATG 
CTTCCTGGTA ATGCTAGAAA GATGGACAAG TCTACTGTTC TACAGAAGAG CATTGATTTT 
TTACGCAAAC ATAAAGAGAT CACTGCACAG TCAGATGCTA GTGAAATTCG ACAGGACTGG 
AAACCTACAT TCCTTAGTAA TGAAGAGTTT ACACAATTAA TGTTAGAGGC TCTTGATGGT 
TTTTTTTTAG CGATCATGAC AGATGGAAGT GTAGTATATG TATCTGAGAC GGTAACTTCG 
TTACTTGAAC ACTTACCATC TGATCTTGTG GATCAAAGTA TATTTAATTT TATCCCAGAG 
GGAGAACATT CAGAGGTTTA TAAGATACTA TCTACTCACC TGCTGGAAAG TGACTCCTTA 
ACCCCCGAGG ACTTAAAATC AAAAAATCAG TTAGAATTCT GTTGTCACAT GCTTCGAGGA 
ACAATAGACC CAAAGGAGCC ATCCACCTAT GAATATGTGA GATTTATAGG AAATTTTAAA 
TCTTTAAACA GTGTATCAAC TTCAACACAT AATGGTTTCG AAGGAACTAT ACAGCGCACA 
CACAGGCCTT CTTATGAAGA TAGAGTTTGT TTCGTAGCTA CTGTCAGATT AGCTACCCCT 
CAGTTCATCA AGGAAATGTG TACTGTTGAA GAACCGAATG AAGAGTTCAC ATCTAGACAC 
AGTTTAGAAT GGAAGTTTCT ATTTCTAGAT CACAGGGCGC CGCCAATCAT AGGCTATCTG 
CCGTTTGAAG TCCTGGGAAC ATCAGGCTAT GATTACTATC ATGTGGACGA CCTAGAAAGT 
CTGGCAAAAT GTCATGAGCA CTTAATGCAA TATGGAAAAG GCAAATCATG TTACTATAGG 
TTCTTGACCA AAGGACAGCA GTGGATTTGG CTTCAGACTC ATTACTATAT CACTTACCAT 
CAGTGGAACT CAAGGCCAGA GTTCATCGTT TGTACTCACA CTGTAGTAAG TTATGCAGAA 
GTTAGGGCTG AAAGACGGCG AGAACTTGGC ATTGAGGAGT CTCTTCCCGA GACAGCTGCT 
GACAAAAGCC AAGATTCTGG GTCTGACAAT CGTATAAACA CAGTGAGTCT CAAGGAAGCA 
CTGGAAAGGT TCGATCACAG CCCAACTCCT TCTGCCTCCT CCAGAAGCTC AAGAAAGTCC 
TCGCACACAG CAGTCTCAGA CCCTTCCTCA ACGCCGACAA AGATCCCCAC TGATACTAGC 
ACTCCTCCCA GACCGCACCT GCCAGCTCAT GAGAAGATGA CACAGCGGAG GTCATCCTTC 
AGTAGTCAGT CCATAAACTC CCAGTCAGTT GGTTCATCAT TAACACAGCC AGCGATGTCT 
CAAGCTGCAA ATTTACCAAT CCCACAAGGC ATGTCACAGT TTCAGCTTTC AGCTCAGTTA 
GGAGCCATGC AGCATCTCAA AGACCAGCTA GAGCAGCGGA CACGCATGAT AGAAGCAAAT 
ATTCATCGGC AGCAAGAAGA ACTAAGGAAA ATTCAAGAAC AACTTCAAAT GGTCCATGGT 
CAAGGGCTAC AGATGTTTTT GCAGCAATCA AACCCTGGAC TGAATTTTGG TTCTGTTCAA 
CTTTCCTCTG GAAATTCCAA TATCCAGCAA CTCACACCTA TAAATATGCA AGGCCAAGTT 
GTCCCTGTTA ACCAGATTCA GAGTGGGGTG AATGCTGGCC ATGTCAGCAC AGGCCAGCAC 
ATGATCCAGC AGCAGACTTT ACAAAGTACA TCAACTCAGC AGAGTCAACA GAGTGTAATG 
AGTGGACACA GTCAGCCAAC GTCTCTTCCA AACCAGACGC CGAGCACTCT GACAGCCCCA 
CTGTACAATA CGATGGTGAT CTCTCAGCCT GCAGCTGGGA GCATGGTCCC GATTCCATCC 
AGTATGCCGC AGAACAGCAC CCAGAGTGCT ACAGTCACCA CGTTCACTCA GGACAGACAG 
ATAAGGTTTT CTCAAGGTCA GCAACTTGTG ACCAAATTAG TGACTGCTCC TGTAGCTTGT 
GGGGCCGTCA TGGTGCCAAG TACCATGCTT ATGGGTCAGG TAGTGACTGC CTATCCTACC 
TTTGCCACAC AACAGCAGCA GGCACAGGCC TTGTCAGTAA CACAGCAACA GCAGCAGCAG 
CAGCAGCAGC AGCAACAGCA GCAGCAGCAG CAGCCGCAGC AGGCGCAGCC GCAGCCCCAG 
TCACAGCAGA GTTCCCAGGA CCAGCCGCAT CCTTCAGTTC AGCAGCCAGC TCAGCTGACC 
CAGCCACCAC AACAGTTCTT ACAGACATCT CGGTTGCTCC ATGGGAATCC TTCGACACAG 
CTCATCCTCT CCGCTGCCTT TCCACTACAA CAGAGCACTT TCCCTCCTTC GCACCACCAG 
CAACACCAGC AACAGCAGCT CCATCGGCAC AGGACTGACA GCCTGACTGA CCCTTCCAAG 
GTCCAGCCAC AGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Clock ( XM_017599364.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017454853.1 Rattus norvegicus clock circadian regulator (Clock), transcript variant X5, mRNA.

Price & Availability↑

CloneID	ORa36000
Clone ID Related Accession (Same CDS sequence)	XM_017599362.1 , XM_017599363.1 , XM_006250869.3 , XM_017599361.1 , XM_017599364.1
Accession Version	XM_017599364.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2595bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	circadian locomoter output cycles protein kaput isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005113.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTGTTTA CCGTAAGCTG TAGTAAAATG AGCTCAATTG TTGACAGAGA TGACAGTAGT 
ATTTTTGATG GATTGGTGGA AGAAGATGAC AAGGACAAAG CAAAAAGAGT ATCTAGAAAC 
AAATCAGAAA AGAAACGTAG AGATCAGTTC AATGTACTCA TTAAGGAACT GGGGTCTATG 
CTTCCTGGTA ATGCTAGAAA GATGGACAAG TCTACTGTTC TACAGAAGAG CATTGATTTT 
TTACGCAAAC ATAAAGAGAT CACTGCACAG TCAGATGCTA GTGAAATTCG ACAGGACTGG 
AAACCTACAT TCCTTAGTAA TGAAGAGTTT ACACAATTAA TGTTAGAGGC TCTTGATGGT 
TTTTTTTTAG CGATCATGAC AGATGGAAGT GTAGTATATG TATCTGAGAC GGTAACTTCG 
TTACTTGAAC ACTTACCATC TGATCTTGTG GATCAAAGTA TATTTAATTT TATCCCAGAG 
GGAGAACATT CAGAGGTTTA TAAGATACTA TCTACTCACC TGCTGGAAAG TGACTCCTTA 
ACCCCCGAGG ACTTAAAATC AAAAAATCAG TTAGAATTCT GTTGTCACAT GCTTCGAGGA 
ACAATAGACC CAAAGGAGCC ATCCACCTAT GAATATGTGA GATTTATAGG AAATTTTAAA 
TCTTTAAACA GTGTATCAAC TTCAACACAT AATGGTTTCG AAGGAACTAT ACAGCGCACA 
CACAGGCCTT CTTATGAAGA TAGAGTTTGT TTCGTAGCTA CTGTCAGATT AGCTACCCCT 
CAGTTCATCA AGGAAATGTG TACTGTTGAA GAACCGAATG AAGAGTTCAC ATCTAGACAC 
AGTTTAGAAT GGAAGTTTCT ATTTCTAGAT CACAGGGCGC CGCCAATCAT AGGCTATCTG 
CCGTTTGAAG TCCTGGGAAC ATCAGGCTAT GATTACTATC ATGTGGACGA CCTAGAAAGT 
CTGGCAAAAT GTCATGAGCA CTTAATGCAA TATGGAAAAG GCAAATCATG TTACTATAGG 
TTCTTGACCA AAGGACAGCA GTGGATTTGG CTTCAGACTC ATTACTATAT CACTTACCAT 
CAGTGGAACT CAAGGCCAGA GTTCATCGTT TGTACTCACA CTGTAGTAAG TTATGCAGAA 
GTTAGGGCTG AAAGACGGCG AGAACTTGGC ATTGAGGAGT CTCTTCCCGA GACAGCTGCT 
GACAAAAGCC AAGATTCTGG GTCTGACAAT CGTATAAACA CAGTGAGTCT CAAGGAAGCA 
CTGGAAAGGT TCGATCACAG CCCAACTCCT TCTGCCTCCT CCAGAAGCTC AAGAAAGTCC 
TCGCACACAG CAGTCTCAGA CCCTTCCTCA ACGCCGACAA AGATCCCCAC TGATACTAGC 
ACTCCTCCCA GACCGCACCT GCCAGCTCAT GAGAAGATGA CACAGCGGAG GTCATCCTTC 
AGTAGTCAGT CCATAAACTC CCAGTCAGTT GGTTCATCAT TAACACAGCC AGCGATGTCT 
CAAGCTGCAA ATTTACCAAT CCCACAAGGC ATGTCACAGT TTCAGCTTTC AGCTCAGTTA 
GGAGCCATGC AGCATCTCAA AGACCAGCTA GAGCAGCGGA CACGCATGAT AGAAGCAAAT 
ATTCATCGGC AGCAAGAAGA ACTAAGGAAA ATTCAAGAAC AACTTCAAAT GGTCCATGGT 
CAAGGGCTAC AGATGTTTTT GCAGCAATCA AACCCTGGAC TGAATTTTGG TTCTGTTCAA 
CTTTCCTCTG GAAATTCCAA TATCCAGCAA CTCACACCTA TAAATATGCA AGGCCAAGTT 
GTCCCTGTTA ACCAGATTCA GAGTGGGGTG AATGCTGGCC ATGTCAGCAC AGGCCAGCAC 
ATGATCCAGC AGCAGACTTT ACAAAGTACA TCAACTCAGC AGAGTCAACA GAGTGTAATG 
AGTGGACACA GTCAGCCAAC GTCTCTTCCA AACCAGACGC CGAGCACTCT GACAGCCCCA 
CTGTACAATA CGATGGTGAT CTCTCAGCCT GCAGCTGGGA GCATGGTCCC GATTCCATCC 
AGTATGCCGC AGAACAGCAC CCAGAGTGCT ACAGTCACCA CGTTCACTCA GGACAGACAG 
ATAAGGTTTT CTCAAGGTCA GCAACTTGTG ACCAAATTAG TGACTGCTCC TGTAGCTTGT 
GGGGCCGTCA TGGTGCCAAG TACCATGCTT ATGGGTCAGG TAGTGACTGC CTATCCTACC 
TTTGCCACAC AACAGCAGCA GGCACAGGCC TTGTCAGTAA CACAGCAACA GCAGCAGCAG 
CAGCAGCAGC AGCAACAGCA GCAGCAGCAG CAGCCGCAGC AGGCGCAGCC GCAGCCCCAG 
TCACAGCAGA GTTCCCAGGA CCAGCCGCAT CCTTCAGTTC AGCAGCCAGC TCAGCTGACC 
CAGCCACCAC AACAGTTCTT ACAGACATCT CGGTTGCTCC ATGGGAATCC TTCGACACAG 
CTCATCCTCT CCGCTGCCTT TCCACTACAA CAGAGCACTT TCCCTCCTTC GCACCACCAG 
CAACACCAGC AACAGCAGCT CCATCGGCAC AGGACTGACA GCCTGACTGA CCCTTCCAAG 
GTCCAGCCAC AGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017454853.1
CDS	458..3052
Translation	MLFTVSCSKMSSIVDRDDSSIFDGLVEEDDKDKAKRVSRNKSEKKRRDQFNVLIKELGSMLPGNARKMDKSTVLQKSIDFLRKHKEITAQSDASEIRQDWKPTFLSNEEFTQLMLEALDGFFLAIMTDGSVVYVSETVTSLLEHLPSDLVDQSIFNFIPEGEHSEVYKILSTHLLESDSLTPEDLKSKNQLEFCCHMLRGTIDPKEPSTYEYVRFIGNFKSLNSVSTSTHNGFEGTIQRTHRPSYEDRVCFVATVRLATPQFIKEMCTVEEPNEEFTSRHSLEWKFLFLDHRAPPIIGYLPFEVLGTSGYDYYHVDDLESLAKCHEHLMQYGKGKSCYYRFLTKGQQWIWLQTHYYITYHQWNSRPEFIVCTHTVVSYAEVRAERRRELGIEESLPETAADKSQDSGSDNRINTVSLKEALERFDHSPTPSASSRSSRKSSHTAVSDPSSTPTKIPTDTSTPPRPHLPAHEKMTQRRSSFSSQSINSQSVGSSLTQPAMSQAANLPIPQGMSQFQLSAQLGAMQHLKDQLEQRTRMIEANIHRQQEELRKIQEQLQMVHGQGLQMFLQQSNPGLNFGSVQLSSGNSNIQQLTPINMQGQVVPVNQIQSGVNAGHVSTGQHMIQQQTLQSTSTQQSQQSVMSGHSQPTSLPNQTPSTLTAPLYNTMVISQPAAGSMVPIPSSMPQNSTQSATVTTFTQDRQIRFSQGQQLVTKLVTAPVACGAVMVPSTMLMGQVVTAYPTFATQQQQAQALSVTQQQQQQQQQQQQQQQQQPQQAQPQPQSQQSSQDQPHPSVQQPAQLTQPPQQFLQTSRLLHGNPSTQLILSAAFPLQQSTFPPSHHQQHQQQQLHRHRTDSLTDPSKVQPQ

Target ORF information:

RefSeq Version	XM_017599364.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus clock circadian regulator (Clock), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017599364.1

ORF Insert Sequence:

ATGTTGTTTA CCGTAAGCTG TAGTAAAATG AGCTCAATTG TTGACAGAGA TGACAGTAGT 
ATTTTTGATG GATTGGTGGA AGAAGATGAC AAGGACAAAG CAAAAAGAGT ATCTAGAAAC 
AAATCAGAAA AGAAACGTAG AGATCAGTTC AATGTACTCA TTAAGGAACT GGGGTCTATG 
CTTCCTGGTA ATGCTAGAAA GATGGACAAG TCTACTGTTC TACAGAAGAG CATTGATTTT 
TTACGCAAAC ATAAAGAGAT CACTGCACAG TCAGATGCTA GTGAAATTCG ACAGGACTGG 
AAACCTACAT TCCTTAGTAA TGAAGAGTTT ACACAATTAA TGTTAGAGGC TCTTGATGGT 
TTTTTTTTAG CGATCATGAC AGATGGAAGT GTAGTATATG TATCTGAGAC GGTAACTTCG 
TTACTTGAAC ACTTACCATC TGATCTTGTG GATCAAAGTA TATTTAATTT TATCCCAGAG 
GGAGAACATT CAGAGGTTTA TAAGATACTA TCTACTCACC TGCTGGAAAG TGACTCCTTA 
ACCCCCGAGG ACTTAAAATC AAAAAATCAG TTAGAATTCT GTTGTCACAT GCTTCGAGGA 
ACAATAGACC CAAAGGAGCC ATCCACCTAT GAATATGTGA GATTTATAGG AAATTTTAAA 
TCTTTAAACA GTGTATCAAC TTCAACACAT AATGGTTTCG AAGGAACTAT ACAGCGCACA 
CACAGGCCTT CTTATGAAGA TAGAGTTTGT TTCGTAGCTA CTGTCAGATT AGCTACCCCT 
CAGTTCATCA AGGAAATGTG TACTGTTGAA GAACCGAATG AAGAGTTCAC ATCTAGACAC 
AGTTTAGAAT GGAAGTTTCT ATTTCTAGAT CACAGGGCGC CGCCAATCAT AGGCTATCTG 
CCGTTTGAAG TCCTGGGAAC ATCAGGCTAT GATTACTATC ATGTGGACGA CCTAGAAAGT 
CTGGCAAAAT GTCATGAGCA CTTAATGCAA TATGGAAAAG GCAAATCATG TTACTATAGG 
TTCTTGACCA AAGGACAGCA GTGGATTTGG CTTCAGACTC ATTACTATAT CACTTACCAT 
CAGTGGAACT CAAGGCCAGA GTTCATCGTT TGTACTCACA CTGTAGTAAG TTATGCAGAA 
GTTAGGGCTG AAAGACGGCG AGAACTTGGC ATTGAGGAGT CTCTTCCCGA GACAGCTGCT 
GACAAAAGCC AAGATTCTGG GTCTGACAAT CGTATAAACA CAGTGAGTCT CAAGGAAGCA 
CTGGAAAGGT TCGATCACAG CCCAACTCCT TCTGCCTCCT CCAGAAGCTC AAGAAAGTCC 
TCGCACACAG CAGTCTCAGA CCCTTCCTCA ACGCCGACAA AGATCCCCAC TGATACTAGC 
ACTCCTCCCA GACCGCACCT GCCAGCTCAT GAGAAGATGA CACAGCGGAG GTCATCCTTC 
AGTAGTCAGT CCATAAACTC CCAGTCAGTT GGTTCATCAT TAACACAGCC AGCGATGTCT 
CAAGCTGCAA ATTTACCAAT CCCACAAGGC ATGTCACAGT TTCAGCTTTC AGCTCAGTTA 
GGAGCCATGC AGCATCTCAA AGACCAGCTA GAGCAGCGGA CACGCATGAT AGAAGCAAAT 
ATTCATCGGC AGCAAGAAGA ACTAAGGAAA ATTCAAGAAC AACTTCAAAT GGTCCATGGT 
CAAGGGCTAC AGATGTTTTT GCAGCAATCA AACCCTGGAC TGAATTTTGG TTCTGTTCAA 
CTTTCCTCTG GAAATTCCAA TATCCAGCAA CTCACACCTA TAAATATGCA AGGCCAAGTT 
GTCCCTGTTA ACCAGATTCA GAGTGGGGTG AATGCTGGCC ATGTCAGCAC AGGCCAGCAC 
ATGATCCAGC AGCAGACTTT ACAAAGTACA TCAACTCAGC AGAGTCAACA GAGTGTAATG 
AGTGGACACA GTCAGCCAAC GTCTCTTCCA AACCAGACGC CGAGCACTCT GACAGCCCCA 
CTGTACAATA CGATGGTGAT CTCTCAGCCT GCAGCTGGGA GCATGGTCCC GATTCCATCC 
AGTATGCCGC AGAACAGCAC CCAGAGTGCT ACAGTCACCA CGTTCACTCA GGACAGACAG 
ATAAGGTTTT CTCAAGGTCA GCAACTTGTG ACCAAATTAG TGACTGCTCC TGTAGCTTGT 
GGGGCCGTCA TGGTGCCAAG TACCATGCTT ATGGGTCAGG TAGTGACTGC CTATCCTACC 
TTTGCCACAC AACAGCAGCA GGCACAGGCC TTGTCAGTAA CACAGCAACA GCAGCAGCAG 
CAGCAGCAGC AGCAACAGCA GCAGCAGCAG CAGCCGCAGC AGGCGCAGCC GCAGCCCCAG 
TCACAGCAGA GTTCCCAGGA CCAGCCGCAT CCTTCAGTTC AGCAGCCAGC TCAGCTGACC 
CAGCCACCAC AACAGTTCTT ACAGACATCT CGGTTGCTCC ATGGGAATCC TTCGACACAG 
CTCATCCTCT CCGCTGCCTT TCCACTACAA CAGAGCACTT TCCCTCCTTC GCACCACCAG 
CAACACCAGC AACAGCAGCT CCATCGGCAC AGGACTGACA GCCTGACTGA CCCTTCCAAG 
GTCCAGCCAC AGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Clock ( XM_006250870.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006250932.1 Rattus norvegicus clock circadian regulator (Clock), transcript variant X6, mRNA.

Price & Availability↑

CloneID	ORa36001
Clone ID Related Accession (Same CDS sequence)	XM_006250870.3
Accession Version	XM_006250870.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2592bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	circadian locomoter output cycles protein kaput isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005113.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006250870.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTGTTTA CCGTAAGCTG TAGTAAAATG AGCTCAATTG TTGACAGAGA TGACAGTAGT 
ATTTTTGATG GATTGGTGGA AGAAGATGAC AAGGACAAAG CAAAAAGAGT ATCTAGAAAC 
AAATCAGAAA AGAAACGTAG AGATCAGTTC AATGTACTCA TTAAGGAACT GGGGTCTATG 
CTTCCTGGTA ATGCTAGAAA GATGGACAAG TCTACTGTTC TACAGAAGAG CATTGATTTT 
TTACGCAAAC ATAAAGAGAT CACTGCACAG TCAGATGCTA GTGAAATTCG ACAGGACTGG 
AAACCTACAT TCCTTAGTAA TGAAGAGTTT ACACAATTAA TGTTAGAGGC TCTTGATGGT 
TTTTTTTTAG CGATCATGAC AGATGGAAGT GTAGTATATG TATCTGAGAC GGTAACTTCG 
TTACTTGAAC ACTTACCATC TGATCTTGTG GATCAAAGTA TATTTAATTT TATCCCAGAG 
GGAGAACATT CAGAGGTTTA TAAGATACTA TCTACTCACC TGCTGGAAAG TGACTCCTTA 
ACCCCCGAGG ACTTAAAATC AAAAAATCAG TTAGAATTCT GTTGTCACAT GCTTCGAGGA 
ACAATAGACC CAAAGGAGCC ATCCACCTAT GAATATGTGA GATTTATAGG AAATTTTAAA 
TCTTTAAACA GTGTATCAAC TTCAACACAT AATGGTTTCG AAGGAACTAT ACAGCGCACA 
CACAGGCCTT CTTATGAAGA TAGAGTTTGT TTCGTAGCTA CTGTCAGATT AGCTACCCCT 
CAGTTCATCA AGGAAATGTG TACTGTTGAA GAACCGAATG AAGAGTTCAC ATCTAGACAC 
AGTTTAGAAT GGAAGTTTCT ATTTCTAGAT CACAGGGCGC CGCCAATCAT AGGCTATCTG 
CCGTTTGAAG TCCTGGGAAC ATCAGGCTAT GATTACTATC ATGTGGACGA CCTAGAAAGT 
CTGGCAAAAT GTCATGAGCA CTTAATGCAA TATGGAAAAG GCAAATCATG TTACTATAGG 
TTCTTGACCA AAGGACAGCA GTGGATTTGG CTTCAGACTC ATTACTATAT CACTTACCAT 
CAGTGGAACT CAAGGCCAGA GTTCATCGTT TGTACTCACA CTGTAGTAAG TTATGCAGAA 
GTTAGGGCTG AAAGACGGCG AGAACTTGGC ATTGAGGAGT CTCTTCCCGA GACAGCTGCT 
GACAAAAGCC AAGATTCTGG GTCTGACAAT CGTATAAACA CAGTGAGTCT CAAGGAAGCA 
CTGGAAAGGT TCGATCACAG CCCAACTCCT TCTGCCTCCT CCAGAAGCTC AAGAAAGTCC 
TCGCACACAG CAGTCTCAGA CCCTTCCTCA ACGCCGACAA AGATCCCCAC TGATACTAGC 
ACTCCTCCCA GACCGCACCT GCCAGCTCAT GAGAAGATGA CACAGCGGAG GTCATCCTTC 
AGTAGTCAGT CCATAAACTC CCAGTCAGTT GGTTCATCAT TAACACAGCC AGCGATGTCT 
CAAGCTGCAA ATTTACCAAT CCCACAAGGC ATGTCACAGT TTCAGCTTTC AGCTCAGTTA 
GGAGCCATGC AGCATCTCAA AGACCAGCTA GAGCAGCGGA CACGCATGAT AGAAGCAAAT 
ATTCATCGGC AGCAAGAAGA ACTAAGGAAA ATTCAAGAAC AACTTCAAAT GGTCCATGGT 
CAAGGGCTAC AGATGTTTTT GCAGCAATCA AACCCTGGAC TGAATTTTGG TTCTGTTCAA 
CTTTCCTCTG GAAATTCCAA TATCCAGCAA CTCACACCTA TAAATATGCA AGGCCAAGTT 
GTCCCTGTTA ACCAGATTCA GAGTGGGGTG AATGCTGGCC ATGTCAGCAC AGGCCAGCAC 
ATGATCCAGC AGCAGACTTT ACAAAGTACA TCAACTCAGA GTCAACAGAG TGTAATGAGT 
GGACACAGTC AGCCAACGTC TCTTCCAAAC CAGACGCCGA GCACTCTGAC AGCCCCACTG 
TACAATACGA TGGTGATCTC TCAGCCTGCA GCTGGGAGCA TGGTCCCGAT TCCATCCAGT 
ATGCCGCAGA ACAGCACCCA GAGTGCTACA GTCACCACGT TCACTCAGGA CAGACAGATA 
AGGTTTTCTC AAGGTCAGCA ACTTGTGACC AAATTAGTGA CTGCTCCTGT AGCTTGTGGG 
GCCGTCATGG TGCCAAGTAC CATGCTTATG GGTCAGGTAG TGACTGCCTA TCCTACCTTT 
GCCACACAAC AGCAGCAGGC ACAGGCCTTG TCAGTAACAC AGCAACAGCA GCAGCAGCAG 
CAGCAGCAGC AACAGCAGCA GCAGCAGCAG CCGCAGCAGG CGCAGCCGCA GCCCCAGTCA 
CAGCAGAGTT CCCAGGACCA GCCGCATCCT TCAGTTCAGC AGCCAGCTCA GCTGACCCAG 
CCACCACAAC AGTTCTTACA GACATCTCGG TTGCTCCATG GGAATCCTTC GACACAGCTC 
ATCCTCTCCG CTGCCTTTCC ACTACAACAG AGCACTTTCC CTCCTTCGCA CCACCAGCAA 
CACCAGCAAC AGCAGCTCCA TCGGCACAGG ACTGACAGCC TGACTGACCC TTCCAAGGTC 
CAGCCACAGT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006250932.1
CDS	313..2904
Translation	MLFTVSCSKMSSIVDRDDSSIFDGLVEEDDKDKAKRVSRNKSEKKRRDQFNVLIKELGSMLPGNARKMDKSTVLQKSIDFLRKHKEITAQSDASEIRQDWKPTFLSNEEFTQLMLEALDGFFLAIMTDGSVVYVSETVTSLLEHLPSDLVDQSIFNFIPEGEHSEVYKILSTHLLESDSLTPEDLKSKNQLEFCCHMLRGTIDPKEPSTYEYVRFIGNFKSLNSVSTSTHNGFEGTIQRTHRPSYEDRVCFVATVRLATPQFIKEMCTVEEPNEEFTSRHSLEWKFLFLDHRAPPIIGYLPFEVLGTSGYDYYHVDDLESLAKCHEHLMQYGKGKSCYYRFLTKGQQWIWLQTHYYITYHQWNSRPEFIVCTHTVVSYAEVRAERRRELGIEESLPETAADKSQDSGSDNRINTVSLKEALERFDHSPTPSASSRSSRKSSHTAVSDPSSTPTKIPTDTSTPPRPHLPAHEKMTQRRSSFSSQSINSQSVGSSLTQPAMSQAANLPIPQGMSQFQLSAQLGAMQHLKDQLEQRTRMIEANIHRQQEELRKIQEQLQMVHGQGLQMFLQQSNPGLNFGSVQLSSGNSNIQQLTPINMQGQVVPVNQIQSGVNAGHVSTGQHMIQQQTLQSTSTQSQQSVMSGHSQPTSLPNQTPSTLTAPLYNTMVISQPAAGSMVPIPSSMPQNSTQSATVTTFTQDRQIRFSQGQQLVTKLVTAPVACGAVMVPSTMLMGQVVTAYPTFATQQQQAQALSVTQQQQQQQQQQQQQQQQQPQQAQPQPQSQQSSQDQPHPSVQQPAQLTQPPQQFLQTSRLLHGNPSTQLILSAAFPLQQSTFPPSHHQQHQQQQLHRHRTDSLTDPSKVQPQ

Target ORF information:

RefSeq Version	XM_006250870.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus clock circadian regulator (Clock), transcript variant X6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006250870.3

ORF Insert Sequence:

ATGTTGTTTA CCGTAAGCTG TAGTAAAATG AGCTCAATTG TTGACAGAGA TGACAGTAGT 
ATTTTTGATG GATTGGTGGA AGAAGATGAC AAGGACAAAG CAAAAAGAGT ATCTAGAAAC 
AAATCAGAAA AGAAACGTAG AGATCAGTTC AATGTACTCA TTAAGGAACT GGGGTCTATG 
CTTCCTGGTA ATGCTAGAAA GATGGACAAG TCTACTGTTC TACAGAAGAG CATTGATTTT 
TTACGCAAAC ATAAAGAGAT CACTGCACAG TCAGATGCTA GTGAAATTCG ACAGGACTGG 
AAACCTACAT TCCTTAGTAA TGAAGAGTTT ACACAATTAA TGTTAGAGGC TCTTGATGGT 
TTTTTTTTAG CGATCATGAC AGATGGAAGT GTAGTATATG TATCTGAGAC GGTAACTTCG 
TTACTTGAAC ACTTACCATC TGATCTTGTG GATCAAAGTA TATTTAATTT TATCCCAGAG 
GGAGAACATT CAGAGGTTTA TAAGATACTA TCTACTCACC TGCTGGAAAG TGACTCCTTA 
ACCCCCGAGG ACTTAAAATC AAAAAATCAG TTAGAATTCT GTTGTCACAT GCTTCGAGGA 
ACAATAGACC CAAAGGAGCC ATCCACCTAT GAATATGTGA GATTTATAGG AAATTTTAAA 
TCTTTAAACA GTGTATCAAC TTCAACACAT AATGGTTTCG AAGGAACTAT ACAGCGCACA 
CACAGGCCTT CTTATGAAGA TAGAGTTTGT TTCGTAGCTA CTGTCAGATT AGCTACCCCT 
CAGTTCATCA AGGAAATGTG TACTGTTGAA GAACCGAATG AAGAGTTCAC ATCTAGACAC 
AGTTTAGAAT GGAAGTTTCT ATTTCTAGAT CACAGGGCGC CGCCAATCAT AGGCTATCTG 
CCGTTTGAAG TCCTGGGAAC ATCAGGCTAT GATTACTATC ATGTGGACGA CCTAGAAAGT 
CTGGCAAAAT GTCATGAGCA CTTAATGCAA TATGGAAAAG GCAAATCATG TTACTATAGG 
TTCTTGACCA AAGGACAGCA GTGGATTTGG CTTCAGACTC ATTACTATAT CACTTACCAT 
CAGTGGAACT CAAGGCCAGA GTTCATCGTT TGTACTCACA CTGTAGTAAG TTATGCAGAA 
GTTAGGGCTG AAAGACGGCG AGAACTTGGC ATTGAGGAGT CTCTTCCCGA GACAGCTGCT 
GACAAAAGCC AAGATTCTGG GTCTGACAAT CGTATAAACA CAGTGAGTCT CAAGGAAGCA 
CTGGAAAGGT TCGATCACAG CCCAACTCCT TCTGCCTCCT CCAGAAGCTC AAGAAAGTCC 
TCGCACACAG CAGTCTCAGA CCCTTCCTCA ACGCCGACAA AGATCCCCAC TGATACTAGC 
ACTCCTCCCA GACCGCACCT GCCAGCTCAT GAGAAGATGA CACAGCGGAG GTCATCCTTC 
AGTAGTCAGT CCATAAACTC CCAGTCAGTT GGTTCATCAT TAACACAGCC AGCGATGTCT 
CAAGCTGCAA ATTTACCAAT CCCACAAGGC ATGTCACAGT TTCAGCTTTC AGCTCAGTTA 
GGAGCCATGC AGCATCTCAA AGACCAGCTA GAGCAGCGGA CACGCATGAT AGAAGCAAAT 
ATTCATCGGC AGCAAGAAGA ACTAAGGAAA ATTCAAGAAC AACTTCAAAT GGTCCATGGT 
CAAGGGCTAC AGATGTTTTT GCAGCAATCA AACCCTGGAC TGAATTTTGG TTCTGTTCAA 
CTTTCCTCTG GAAATTCCAA TATCCAGCAA CTCACACCTA TAAATATGCA AGGCCAAGTT 
GTCCCTGTTA ACCAGATTCA GAGTGGGGTG AATGCTGGCC ATGTCAGCAC AGGCCAGCAC 
ATGATCCAGC AGCAGACTTT ACAAAGTACA TCAACTCAGA GTCAACAGAG TGTAATGAGT 
GGACACAGTC AGCCAACGTC TCTTCCAAAC CAGACGCCGA GCACTCTGAC AGCCCCACTG 
TACAATACGA TGGTGATCTC TCAGCCTGCA GCTGGGAGCA TGGTCCCGAT TCCATCCAGT 
ATGCCGCAGA ACAGCACCCA GAGTGCTACA GTCACCACGT TCACTCAGGA CAGACAGATA 
AGGTTTTCTC AAGGTCAGCA ACTTGTGACC AAATTAGTGA CTGCTCCTGT AGCTTGTGGG 
GCCGTCATGG TGCCAAGTAC CATGCTTATG GGTCAGGTAG TGACTGCCTA TCCTACCTTT 
GCCACACAAC AGCAGCAGGC ACAGGCCTTG TCAGTAACAC AGCAACAGCA GCAGCAGCAG 
CAGCAGCAGC AACAGCAGCA GCAGCAGCAG CCGCAGCAGG CGCAGCCGCA GCCCCAGTCA 
CAGCAGAGTT CCCAGGACCA GCCGCATCCT TCAGTTCAGC AGCCAGCTCA GCTGACCCAG 
CCACCACAAC AGTTCTTACA GACATCTCGG TTGCTCCATG GGAATCCTTC GACACAGCTC 
ATCCTCTCCG CTGCCTTTCC ACTACAACAG AGCACTTTCC CTCCTTCGCA CCACCAGCAA 
CACCAGCAAC AGCAGCTCCA TCGGCACAGG ACTGACAGCC TGACTGACCC TTCCAAGGTC 
CAGCCACAGT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

CLOCK Acetylates ASS1 to Drive Circadian Rhythm of Ureagenesis.
Molecular cell68(1)198-209.e6(2017 Oct)
Lin R,Mo Y,Zha H,Qu Z,Xie P,Zhu ZJ,Xu Y,Xiong Y,Guan KL

[Expression profiles of miRNA-182 and Clock mRNA in the pineal gland of neonatal rats with hypoxic-ischemic brain damage].
Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics18(3)270-6(2016 Mar)
Han X,Ding X,Xu LX,Liu MH,Feng X

A role for the circadian clock protein Per1 in the regulation of the NaCl co-transporter (NCC) and the with-no-lysine kinase (WNK) cascade in mouse distal convoluted tubule cells.
The Journal of biological chemistry289(17)11791-806(2014 Apr)
Richards J,Ko B,All S,Cheng KY,Hoover RS,Gumz ML

A novel protein, CHRONO, functions as a core component of the mammalian circadian clock.
PLoS biology12(4)e1001839(2014 Apr)
Goriki A,Hatanaka F,Myung J,Kim JK,Yoritaka T,Tanoue S,Abe T,Kiyonari H,Fujimoto K,Kato Y,Todo T,Matsubara A,Forger D,Takumi T

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Clock cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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