Trdn cDNA ORF clone, Rattus norvegicus(Norway rat)

Impact of lactobacilli on orally acquired listeriosis.
Archambaud C, Nahori MA, Soubigou G, B?cavin C, Laval L, Lechat P, Smokvina T, Langella P, Lecuit M, Cossart P
Proceedings of the National Academy of Sciences of the United States of America109(41)16684-9(2012 Oct)

Role of triadin in the organization of reticulum membrane at the muscle triad.
Fourest-Lieuvin A, Rendu J, Osseni A, Pernet-Gallay K, Rossi D, Oddoux S, Brocard J, Sorrentino V, Marty I, Faur? J
Journal of cell science125(Pt 14)3443-53(2012 Jul)

Absence of triadin, a protein of the calcium release complex, is responsible for cardiac arrhythmia with sudden death in human.
Roux-Buisson N, Cacheux M, Fourest-Lieuvin A, Fauconnier J, Brocard J, Denjoy I, Durand P, Guicheney P, Kyndt F, Leenhardt A, Le Marec H, Lucet V, Mabo P, Probst V, Monnier N, Ray PF, Santoni E, Tr?meaux P, Lacampagne A, Faur? J, Lunardi J, Marty I
Human molecular genetics21(12)2759-67(2012 Jun)

Trisk 32 regulates IP(3) receptors in rat skeletal myoblasts.
Ol?h T, Fodor J, Oddoux S, Ruzsnavszky O, Marty I, Csernoch L
Pflugers Archiv : European journal of physiology462(4)599-610(2011 Oct)

Ablation of triadin causes loss of cardiac Ca2+ release units, impaired excitation-contraction coupling, and cardiac arrhythmias.
Chopra N, Yang T, Asghari P, Moore ED, Huke S, Akin B, Cattolica RA, Perez CF, Hlaing T, Knollmann-Ritschel BE, Jones LR, Pessah IN, Allen PD, Franzini-Armstrong C, Knollmann BC
Proceedings of the National Academy of Sciences of the United States of America106(18)7636-41(2009 May)

findings show that Trisk 32 not only co-localizes with, but directly contributes to, the regulation of Ca(2+) release via IP(3) receptors
Title: Trisk 32 regulates IP(3) receptors in rat skeletal myoblasts.

Trisk 95 negatively regulates ryanodine receptor function by suppressing localized calcium release events and global calcium signals in cultured muscle cells.
Title: Altered expression of triadin 95 causes parallel changes in localized Ca2+ release events and global Ca2+ signals in skeletal muscle cells in culture.

proteasome inhibition led to an accumulation of two new modified forms of triadin-1 that were seen with triadin-1 only when it is not glycosylated on Asn(75).
Title: Inefficient glycosylation leads to high steady-state levels of actively degrading cardiac triadin-1.

Calsequestrin (CASQ2) stabilizes sarcoplasmic reticulum Ca2+ release by inhibiting the RyR2 channel through interaction with triadin (Trd).
Title: Protein protein interactions between triadin and calsequestrin are involved in modulation of sarcoplasmic reticulum calcium release in cardiac myocytes.

In conclusion, the RyR-interacting molecule T95, recently shown to inhibit the excitation-contraction coupling, has also the ability to interfere with the skeletal muscle Ca2+ signalling by depressing thapsigargin-dependent Ca2+ release and influx.
Title: Retrograde regulation of store-operated calcium channels by the ryanodine receptor-associated protein triadin 95 in rat skeletal myotubes.