Slc23a2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Slc23a2
Entrez Gene ID	50622
Full Name	solute carrier family 23 member 2
Synonyms	SVCT2
General protein information	Preferred Names solute carrier family 23 member 2 Names solute carrier family 23 member 2 Na(+)/L-ascorbic acid transporter 2 sodium-coupled ascorbic acid transporter 2 sodium-dependent vitamin C transporter 2 solute carrier family 23 (ascorbic acid transporter), member 2 solute carrier family 23 (nucleobase transporters), member 2
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 3 Map Location: 3q36
Summary	mediates concentrative, high-affinity L-ascorbic acid transport which is driven by the Na+ electrochemical gradient [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_017316.2	NP_059012.2	solute carrier family 23 member 2
XM_006235068.3	XP_006235130.1	solute carrier family 23 member 2 isoform X1
XM_006235069.2	XP_006235131.1	solute carrier family 23 member 2 isoform X2
XM_006235067.3	XP_006235129.1	solute carrier family 23 member 2 isoform X1

Pathways from BioSystems

Homologies

	SLC23A1	XP_001115635.1
Oryza sativa (rice)	Os08g0420600	NP_001061818.1
Oryza sativa (rice)	Os03g0823800	NP_001051745.1
Arabidopsis thaliana (thale cress)	AT5G49990	NP_199810.2
Oryza sativa (rice)	Os02g0741800	NP_001048084.1
Xenopus tropicalis (tropical clawed frog)	slc23a2	NP_001120161.1
Gallus gallus (chicken)	SLC23A2	NP_001138699.1
Arabidopsis thaliana (thale cress)	AT5G62890	NP_001032127.2
Homo sapiens (human)	SLC23A2	NP_005107.4
Mus musculus (house mouse)	Slc23a2	NP_061294.2
Danio rerio (zebrafish)	slc23a2	XP_002663244.1
Oryza sativa (rice)	Os09g0381100	NP_001063058.1
Pan troglodytes (chimpanzee)	SLC23A2	XP_001164789.2
Canis lupus familiaris (dog)	SLC23A2	NP_001103426.1
Bos taurus (cattle)	SLC23A2	NP_001192359.1
Rattus norvegicus (Norway rat)	Slc23a2	NP_059012.2

Gene Ontology
Bibliography

Related articles in PubMed

SVCT2 Expression and Function in Reactive Astrocytes Is a Common Event in Different Brain Pathologies.
Salazar K, Mart?nez F, P?rez-Mart?n M, Cifuentes M, Trigueros L, Ferrada L, Espinoza F, Saldivia N, Bertinat R, Forman K, Oviedo MJ, L?pez-Gambero AJ, Bonansco C, Bongarzone ER, Nualart F
Molecular neurobiology(2017 Sep)

SVCT2, a potential therapeutic target, protects against oxidative stress during ethanol-induced neurotoxicity via JNK/p38 MAPKs, NF-?B and miRNA125a-5p.
Tian H, Ye X, Hou X, Yang X, Yang J, Wu C
Free radical biology & medicine96362-73(2016 07)

Orally administrated ascorbic acid suppresses neuronal damage and modifies expression of SVCT2 and GLUT1 in the brain of diabetic rats with cerebral ischemia-reperfusion.
Iwata N, Okazaki M, Xuan M, Kamiuchi S, Matsuzaki H, Hibino Y
Nutrients6(4)1554-77(2014 Apr)

Liver metabolic/oxidative stress induces hepatic and extrahepatic changes in the expression of the vitamin C transporters SVCT1 and SVCT2.
Hierro C, Monte MJ, Lozano E, Gonzalez-Sanchez E, Marin JJ, Macias RI
European journal of nutrition53(2)401-12(2014)

Downregulation of vitamin C transporter SVCT-2 in doxorubicin-induced cardiomyocyte injury.
Ludke AR, Sharma AK, Akolkar G, Bajpai G, Singal PK
American journal of physiology. Cell physiology303(6)C645-53(2012 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

We speculate that SVCT2, possibly regulated by JNK/p38 MAPKs, NF-kappaB signaling and miR-125a-5p, has a neuroprotective effect against EtOH-induced oxidative stress. Promotion of SVCT2 expression or stimulation of SVCT2 activity may be a promising therapeutic strategy for the prevention of EtOH-associated neurodegeneration.
Title: SVCT2, a potential therapeutic target, protects against oxidative stress during ethanol-induced neurotoxicity via JNK/p38 MAPKs, NF-?B and miRNA125a-5p.

Expression of SVCT2 was upregulated in neurons after middle cerebral artery occlusion and reperfusion in the nondiabetic cortex, accompanied by an increase in total ascorbic acid in the tissue, and these responses were suppressed in the diabetic rats.
Title: Orally administrated ascorbic acid suppresses neuronal damage and modifies expression of SVCT2 and GLUT1 in the brain of diabetic rats with cerebral ischemia-reperfusion.

metabolic/oxidative stress in the liver induce different responses in the expression of ascorbic acid transporters SVCT1 and SVCT2 in intrahepatic and extrahepatic tissues, which may affect the overall bioavailability and cellular uptake of this vitamin
Title: Liver metabolic/oxidative stress induces hepatic and extrahepatic changes in the expression of the vitamin C transporters SVCT1 and SVCT2.

Expression and localization of sodium-dependent vitamin C transporter-2 in the sarcolemma is reduced by doxorubicin, a change blunted by vitamin C supplementation.
Title: Downregulation of vitamin C transporter SVCT-2 in doxorubicin-induced cardiomyocyte injury.

glutathione depletion failed to affect ascorbic acid transport, and SVCT1 and SVCT2 expression in hepatoma cells.
Title: Essential role of intracellular glutathione in controlling ascorbic acid transporter expression and function in rat hepatocytes and hepatoma cells.

The following Slc23a2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Slc23a2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa03628	NM_017316.2 Latest version!	Rattus norvegicus solute carrier family 23 member 2 (Slc23a2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
ORa03628	XM_006235067.3 Latest version!	Rattus norvegicus solute carrier family 23 member 2 (Slc23a2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
ORa03628	XM_006235068.3 Latest version!	Rattus norvegicus solute carrier family 23 member 2 (Slc23a2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
ORa26417	XM_006235069.2 Latest version!	Rattus norvegicus solute carrier family 23 member 2 (Slc23a2), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Slc23a2 ( NM_017316.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_059012.2 Rattus norvegicus solute carrier family 23 member 2 (Slc23a2), mRNA.

Price & Availability↑

CloneID	ORa03628
Clone ID Related Accession (Same CDS sequence)	NM_017316.2 , XM_006235068.3 , XM_006235067.3
Accession Version	NM_017316.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1944bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-21
Organism	Rattus norvegicus(Norway rat)
Product	solute carrier family 23 member 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AF080453.1, AC109886.6 and AA964954.1. On Sep 28, 2011 this sequence version replaced NM_017316.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF080453.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGATGGGTG TCGGCAAGAA CACATCAAAG TCGGTGGAGG TTGGGGGCTC CACAGAAGGC 
AAATATGAAG AGGAGGCCAA GCGCCCCGAT TTCTTTACTC TCCCGGTGGT GATCAATGGT 
GGGGCCACGT CCAGTGGAGA ACAGGACAAT GAAGACACTG AGCTCATGGC CATCTACACC 
ACAGAGAATG GCATTGCAGA GAAGAGCTCT CTCGCAGAGA CCCTGGACAG CACTGGGAGC 
CTGGATCCCC AGAGGTCAGA TATGATCTAC ACTATAGAAG ACGTTCCTCC CTGGTACTTA 
TGCATATTCC TGGGGTTGCA GCACTACCTG ACGTGTTTCA GTGGCACAAT CGCAGTGCCC 
TTTTTGCTGG CTGATGCCAT GTGCGTGGGG GATGACCAGT GGGCCACCAG CCAGCTCATC 
GGGACCATTT TCTTCTGCGT GGGAATCACT ACATTGCTGC AGACAACATT TGGATGCAGG 
TTACCCCTGT TTCAGGCCAG TGCTTTTGCA TTTTTGGCCC CTGCTCGAGC CATCCTGTCT 
TTAGATAAAT GGAAATGTAA CACCACAGAG ATCACAGTTG CCAACGGAAC GGCAGAGCTG 
TTGGAACACA TCTGGCACCC CCGGATCCAA GAGATCCAGG GGGCTATAAT CATGTCCTCA 
CTGATAGAAG TGGTCATTGG CCTCCTTGGC CTGCCTGGGG CTCTGCTGAG GTATATTGGA 
CCCTTGACCA TCACACCCAC CGTGGCCCTC ATTGGCCTCT CTGGTTTCCA GGCAGCAGGA 
GAGCGAGCTG GGAAGCACTG GGGCATTGCC ATGCTGACAA TTTTCCTAGT GTTACTATTC 
TCACAATATG CCAGAAATGT TAAATTTCCT CTCCCAATCT ACAAATCCAA GAAAGGATGG 
ACGGCCTACA AGTTACAACT TTTCAAAATG TTTCCTATAA TCCTGGCTAT CCTCGTGTCC 
TGGCTGCTGT GCTTCATCTT CACGGTGACT GACGTCTTCC CTTCCAACAG CACCGACTAT 
GGCTACTATG CACGCACAGA TGCCAGGAAG GGCGTACTTC TGGTAGCCCC ATGGTTTAAG 
GTTCCATACC CATTTCAGTG GGGGATGCCC ACCGTCTCTG CAGCTGGCGT CATTGGCATG 
CTCAGTGCTG TCGTAGCCAG TATCATTGAG TCCATCGGCG ACTACTATGC CTGCGCCAGG 
CTCTCCTGTG CCCCACCACC TCCTATACAT GCAATAAACA GGGGTATTTT TGTGGAGGGT 
CTTTCTTGTG TTCTCGATGG CGTATTTGGT ACCGGGAATG GCTCTACCTC CTCCAGTCCC 
AATATTGGAG TTTTGGGAAT TACAAAGGTT GGCAGCCGCC GAGTGATCCA GTATGGTGCA 
GCTCTCATGC TGGGCTTGGG CATGATTGGC AAGTTCAGCG CCCTCTTCGC CTCCCTCCCA 
GACCCTGTAC TCGGAGCCCT CTTCTGCACA CTCTTTGGAA TGATCACAGC TGTTGGCCTC 
TCTAACCTGC AGTTCATTGA CTTGAATTCT TCCCGGAACC TATTTGTGCT TGGATTTTCC 
ATCTTCTTTG GGCTTGTTCT TCCAAGTTAC CTCAGACAAA ACCCTCTGGT TACAGGCATA 
ACAGGCATTG ATCAAGTTCT GAATGTCCTT CTCACCACTG CTATGTTCGT CGGAGGCTGT 
GTGGCTTTTA TTTTGGACAA CACCATCCCA GGAACCCCAG AGGAAAGAGG AATCAAGAAA 
TGGAAGAAGG GTGTGAGCAA AGGAAACAAG TCTCTTGACG GCATGGAGTC CTATAATTTG 
CCATTTGGCA TGAACATTAT TAAAAAATAC AGATGCTTCA GCTACCTGCC TATCAGCCCA 
ACCTTTGCAG GTTACACATG GAAAGGCTTT GGGAAGAGTG AGAACAGGCG GAGTTCAGAC 
AAAGACTCCC AGGCCACAGT ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_059012.2
CDS	211..2154
Translation	MMGVGKNTSKSVEVGGSTEGKYEEEAKRPDFFTLPVVINGGATSSGEQDNEDTELMAIYTTENGIAEKSSLAETLDSTGSLDPQRSDMIYTIEDVPPWYLCIFLGLQHYLTCFSGTIAVPFLLADAMCVGDDQWATSQLIGTIFFCVGITTLLQTTFGCRLPLFQASAFAFLAPARAILSLDKWKCNTTEITVANGTAELLEHIWHPRIQEIQGAIIMSSLIEVVIGLLGLPGALLRYIGPLTITPTVALIGLSGFQAAGERAGKHWGIAMLTIFLVLLFSQYARNVKFPLPIYKSKKGWTAYKLQLFKMFPIILAILVSWLLCFIFTVTDVFPSNSTDYGYYARTDARKGVLLVAPWFKVPYPFQWGMPTVSAAGVIGMLSAVVASIIESIGDYYACARLSCAPPPPIHAINRGIFVEGLSCVLDGVFGTGNGSTSSSPNIGVLGITKVGSRRVIQYGAALMLGLGMIGKFSALFASLPDPVLGALFCTLFGMITAVGLSNLQFIDLNSSRNLFVLGFSIFFGLVLPSYLRQNPLVTGITGIDQVLNVLLTTAMFVGGCVAFILDNTIPGTPEERGIKKWKKGVSKGNKSLDGMESYNLPFGMNIIKKYRCFSYLPISPTFAGYTWKGFGKSENRRSSDKDSQATV

Target ORF information:

RefSeq Version	NM_017316.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus solute carrier family 23 member 2 (Slc23a2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_017316.2

ORF Insert Sequence:

ATGATGGGTG TCGGCAAGAA CACATCAAAG TCGGTGGAGG TTGGGGGCTC CACAGAAGGC 
AAATATGAAG AGGAGGCCAA GCGCCCCGAT TTCTTTACTC TCCCGGTGGT GATCAATGGT 
GGGGCCACGT CCAGTGGAGA ACAGGACAAT GAAGACACTG AGCTCATGGC CATCTACACC 
ACAGAGAATG GCATTGCAGA GAAGAGCTCT CTCGCAGAGA CCCTGGACAG CACTGGGAGC 
CTGGATCCCC AGAGGTCAGA TATGATCTAC ACTATAGAAG ACGTTCCTCC CTGGTACTTA 
TGCATATTCC TGGGGTTGCA GCACTACCTG ACGTGTTTCA GTGGCACAAT CGCAGTGCCC 
TTTTTGCTGG CTGATGCCAT GTGCGTGGGG GATGACCAGT GGGCCACCAG CCAGCTCATC 
GGGACCATTT TCTTCTGCGT GGGAATCACT ACATTGCTGC AGACAACATT TGGATGCAGG 
TTACCCCTGT TTCAGGCCAG TGCTTTTGCA TTTTTGGCCC CTGCTCGAGC CATCCTGTCT 
TTAGATAAAT GGAAATGTAA CACCACAGAG ATCACAGTTG CCAACGGAAC GGCAGAGCTG 
TTGGAACACA TCTGGCACCC CCGGATCCAA GAGATCCAGG GGGCTATAAT CATGTCCTCA 
CTGATAGAAG TGGTCATTGG CCTCCTTGGC CTGCCTGGGG CTCTGCTGAG GTATATTGGA 
CCCTTGACCA TCACACCCAC CGTGGCCCTC ATTGGCCTCT CTGGTTTCCA GGCAGCAGGA 
GAGCGAGCTG GGAAGCACTG GGGCATTGCC ATGCTGACAA TTTTCCTAGT GTTACTATTC 
TCACAATATG CCAGAAATGT TAAATTTCCT CTCCCAATCT ACAAATCCAA GAAAGGATGG 
ACGGCCTACA AGTTACAACT TTTCAAAATG TTTCCTATAA TCCTGGCTAT CCTCGTGTCC 
TGGCTGCTGT GCTTCATCTT CACGGTGACT GACGTCTTCC CTTCCAACAG CACCGACTAT 
GGCTACTATG CACGCACAGA TGCCAGGAAG GGCGTACTTC TGGTAGCCCC ATGGTTTAAG 
GTTCCATACC CATTTCAGTG GGGGATGCCC ACCGTCTCTG CAGCTGGCGT CATTGGCATG 
CTCAGTGCTG TCGTAGCCAG TATCATTGAG TCCATCGGCG ACTACTATGC CTGCGCCAGG 
CTCTCCTGTG CCCCACCACC TCCTATACAT GCAATAAACA GGGGTATTTT TGTGGAGGGT 
CTTTCTTGTG TTCTCGATGG CGTATTTGGT ACCGGGAATG GCTCTACCTC CTCCAGTCCC 
AATATTGGAG TTTTGGGAAT TACAAAGGTT GGCAGCCGCC GAGTGATCCA GTATGGTGCA 
GCTCTCATGC TGGGCTTGGG CATGATTGGC AAGTTCAGCG CCCTCTTCGC CTCCCTCCCA 
GACCCTGTAC TCGGAGCCCT CTTCTGCACA CTCTTTGGAA TGATCACAGC TGTTGGCCTC 
TCTAACCTGC AGTTCATTGA CTTGAATTCT TCCCGGAACC TATTTGTGCT TGGATTTTCC 
ATCTTCTTTG GGCTTGTTCT TCCAAGTTAC CTCAGACAAA ACCCTCTGGT TACAGGCATA 
ACAGGCATTG ATCAAGTTCT GAATGTCCTT CTCACCACTG CTATGTTCGT CGGAGGCTGT 
GTGGCTTTTA TTTTGGACAA CACCATCCCA GGAACCCCAG AGGAAAGAGG AATCAAGAAA 
TGGAAGAAGG GTGTGAGCAA AGGAAACAAG TCTCTTGACG GCATGGAGTC CTATAATTTG 
CCATTTGGCA TGAACATTAT TAAAAAATAC AGATGCTTCA GCTACCTGCC TATCAGCCCA 
ACCTTTGCAG GTTACACATG GAAAGGCTTT GGGAAGAGTG AGAACAGGCG GAGTTCAGAC 
AAAGACTCCC AGGCCACAGT ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Slc23a2 ( XM_006235068.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006235130.1 Rattus norvegicus solute carrier family 23 member 2 (Slc23a2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa03628
Clone ID Related Accession (Same CDS sequence)	NM_017316.2 , XM_006235068.3 , XM_006235067.3
Accession Version	XM_006235068.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1944bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	solute carrier family 23 member 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006235068.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATGGGTG TCGGCAAGAA CACATCAAAG TCGGTGGAGG TTGGGGGCTC CACAGAAGGC 
AAATATGAAG AGGAGGCCAA GCGCCCCGAT TTCTTTACTC TCCCGGTGGT GATCAATGGT 
GGGGCCACGT CCAGTGGAGA ACAGGACAAT GAAGACACTG AGCTCATGGC CATCTACACC 
ACAGAGAATG GCATTGCAGA GAAGAGCTCT CTCGCAGAGA CCCTGGACAG CACTGGGAGC 
CTGGATCCCC AGAGGTCAGA TATGATCTAC ACTATAGAAG ACGTTCCTCC CTGGTACTTA 
TGCATATTCC TGGGGTTGCA GCACTACCTG ACGTGTTTCA GTGGCACAAT CGCAGTGCCC 
TTTTTGCTGG CTGATGCCAT GTGCGTGGGG GATGACCAGT GGGCCACCAG CCAGCTCATC 
GGGACCATTT TCTTCTGCGT GGGAATCACT ACATTGCTGC AGACAACATT TGGATGCAGG 
TTACCCCTGT TTCAGGCCAG TGCTTTTGCA TTTTTGGCCC CTGCTCGAGC CATCCTGTCT 
TTAGATAAAT GGAAATGTAA CACCACAGAG ATCACAGTTG CCAACGGAAC GGCAGAGCTG 
TTGGAACACA TCTGGCACCC CCGGATCCAA GAGATCCAGG GGGCTATAAT CATGTCCTCA 
CTGATAGAAG TGGTCATTGG CCTCCTTGGC CTGCCTGGGG CTCTGCTGAG GTATATTGGA 
CCCTTGACCA TCACACCCAC CGTGGCCCTC ATTGGCCTCT CTGGTTTCCA GGCAGCAGGA 
GAGCGAGCTG GGAAGCACTG GGGCATTGCC ATGCTGACAA TTTTCCTAGT GTTACTATTC 
TCACAATATG CCAGAAATGT TAAATTTCCT CTCCCAATCT ACAAATCCAA GAAAGGATGG 
ACGGCCTACA AGTTACAACT TTTCAAAATG TTTCCTATAA TCCTGGCTAT CCTCGTGTCC 
TGGCTGCTGT GCTTCATCTT CACGGTGACT GACGTCTTCC CTTCCAACAG CACCGACTAT 
GGCTACTATG CACGCACAGA TGCCAGGAAG GGCGTACTTC TGGTAGCCCC ATGGTTTAAG 
GTTCCATACC CATTTCAGTG GGGGATGCCC ACCGTCTCTG CAGCTGGCGT CATTGGCATG 
CTCAGTGCTG TCGTAGCCAG TATCATTGAG TCCATCGGCG ACTACTATGC CTGCGCCAGG 
CTCTCCTGTG CCCCACCACC TCCTATACAT GCAATAAACA GGGGTATTTT TGTGGAGGGT 
CTTTCTTGTG TTCTCGATGG CGTATTTGGT ACCGGGAATG GCTCTACCTC CTCCAGTCCC 
AATATTGGAG TTTTGGGAAT TACAAAGGTT GGCAGCCGCC GAGTGATCCA GTATGGTGCA 
GCTCTCATGC TGGGCTTGGG CATGATTGGC AAGTTCAGCG CCCTCTTCGC CTCCCTCCCA 
GACCCTGTAC TCGGAGCCCT CTTCTGCACA CTCTTTGGAA TGATCACAGC TGTTGGCCTC 
TCTAACCTGC AGTTCATTGA CTTGAATTCT TCCCGGAACC TATTTGTGCT TGGATTTTCC 
ATCTTCTTTG GGCTTGTTCT TCCAAGTTAC CTCAGACAAA ACCCTCTGGT TACAGGCATA 
ACAGGCATTG ATCAAGTTCT GAATGTCCTT CTCACCACTG CTATGTTCGT CGGAGGCTGT 
GTGGCTTTTA TTTTGGACAA CACCATCCCA GGAACCCCAG AGGAAAGAGG AATCAAGAAA 
TGGAAGAAGG GTGTGAGCAA AGGAAACAAG TCTCTTGACG GCATGGAGTC CTATAATTTG 
CCATTTGGCA TGAACATTAT TAAAAAATAC AGATGCTTCA GCTACCTGCC TATCAGCCCA 
ACCTTTGCAG GTTACACATG GAAAGGCTTT GGGAAGAGTG AGAACAGGCG GAGTTCAGAC 
AAAGACTCCC AGGCCACAGT ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006235130.1
CDS	1015..2958
Translation	MMGVGKNTSKSVEVGGSTEGKYEEEAKRPDFFTLPVVINGGATSSGEQDNEDTELMAIYTTENGIAEKSSLAETLDSTGSLDPQRSDMIYTIEDVPPWYLCIFLGLQHYLTCFSGTIAVPFLLADAMCVGDDQWATSQLIGTIFFCVGITTLLQTTFGCRLPLFQASAFAFLAPARAILSLDKWKCNTTEITVANGTAELLEHIWHPRIQEIQGAIIMSSLIEVVIGLLGLPGALLRYIGPLTITPTVALIGLSGFQAAGERAGKHWGIAMLTIFLVLLFSQYARNVKFPLPIYKSKKGWTAYKLQLFKMFPIILAILVSWLLCFIFTVTDVFPSNSTDYGYYARTDARKGVLLVAPWFKVPYPFQWGMPTVSAAGVIGMLSAVVASIIESIGDYYACARLSCAPPPPIHAINRGIFVEGLSCVLDGVFGTGNGSTSSSPNIGVLGITKVGSRRVIQYGAALMLGLGMIGKFSALFASLPDPVLGALFCTLFGMITAVGLSNLQFIDLNSSRNLFVLGFSIFFGLVLPSYLRQNPLVTGITGIDQVLNVLLTTAMFVGGCVAFILDNTIPGTPEERGIKKWKKGVSKGNKSLDGMESYNLPFGMNIIKKYRCFSYLPISPTFAGYTWKGFGKSENRRSSDKDSQATV

Target ORF information:

RefSeq Version	XM_006235068.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus solute carrier family 23 member 2 (Slc23a2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006235068.3

ORF Insert Sequence:

ATGATGGGTG TCGGCAAGAA CACATCAAAG TCGGTGGAGG TTGGGGGCTC CACAGAAGGC 
AAATATGAAG AGGAGGCCAA GCGCCCCGAT TTCTTTACTC TCCCGGTGGT GATCAATGGT 
GGGGCCACGT CCAGTGGAGA ACAGGACAAT GAAGACACTG AGCTCATGGC CATCTACACC 
ACAGAGAATG GCATTGCAGA GAAGAGCTCT CTCGCAGAGA CCCTGGACAG CACTGGGAGC 
CTGGATCCCC AGAGGTCAGA TATGATCTAC ACTATAGAAG ACGTTCCTCC CTGGTACTTA 
TGCATATTCC TGGGGTTGCA GCACTACCTG ACGTGTTTCA GTGGCACAAT CGCAGTGCCC 
TTTTTGCTGG CTGATGCCAT GTGCGTGGGG GATGACCAGT GGGCCACCAG CCAGCTCATC 
GGGACCATTT TCTTCTGCGT GGGAATCACT ACATTGCTGC AGACAACATT TGGATGCAGG 
TTACCCCTGT TTCAGGCCAG TGCTTTTGCA TTTTTGGCCC CTGCTCGAGC CATCCTGTCT 
TTAGATAAAT GGAAATGTAA CACCACAGAG ATCACAGTTG CCAACGGAAC GGCAGAGCTG 
TTGGAACACA TCTGGCACCC CCGGATCCAA GAGATCCAGG GGGCTATAAT CATGTCCTCA 
CTGATAGAAG TGGTCATTGG CCTCCTTGGC CTGCCTGGGG CTCTGCTGAG GTATATTGGA 
CCCTTGACCA TCACACCCAC CGTGGCCCTC ATTGGCCTCT CTGGTTTCCA GGCAGCAGGA 
GAGCGAGCTG GGAAGCACTG GGGCATTGCC ATGCTGACAA TTTTCCTAGT GTTACTATTC 
TCACAATATG CCAGAAATGT TAAATTTCCT CTCCCAATCT ACAAATCCAA GAAAGGATGG 
ACGGCCTACA AGTTACAACT TTTCAAAATG TTTCCTATAA TCCTGGCTAT CCTCGTGTCC 
TGGCTGCTGT GCTTCATCTT CACGGTGACT GACGTCTTCC CTTCCAACAG CACCGACTAT 
GGCTACTATG CACGCACAGA TGCCAGGAAG GGCGTACTTC TGGTAGCCCC ATGGTTTAAG 
GTTCCATACC CATTTCAGTG GGGGATGCCC ACCGTCTCTG CAGCTGGCGT CATTGGCATG 
CTCAGTGCTG TCGTAGCCAG TATCATTGAG TCCATCGGCG ACTACTATGC CTGCGCCAGG 
CTCTCCTGTG CCCCACCACC TCCTATACAT GCAATAAACA GGGGTATTTT TGTGGAGGGT 
CTTTCTTGTG TTCTCGATGG CGTATTTGGT ACCGGGAATG GCTCTACCTC CTCCAGTCCC 
AATATTGGAG TTTTGGGAAT TACAAAGGTT GGCAGCCGCC GAGTGATCCA GTATGGTGCA 
GCTCTCATGC TGGGCTTGGG CATGATTGGC AAGTTCAGCG CCCTCTTCGC CTCCCTCCCA 
GACCCTGTAC TCGGAGCCCT CTTCTGCACA CTCTTTGGAA TGATCACAGC TGTTGGCCTC 
TCTAACCTGC AGTTCATTGA CTTGAATTCT TCCCGGAACC TATTTGTGCT TGGATTTTCC 
ATCTTCTTTG GGCTTGTTCT TCCAAGTTAC CTCAGACAAA ACCCTCTGGT TACAGGCATA 
ACAGGCATTG ATCAAGTTCT GAATGTCCTT CTCACCACTG CTATGTTCGT CGGAGGCTGT 
GTGGCTTTTA TTTTGGACAA CACCATCCCA GGAACCCCAG AGGAAAGAGG AATCAAGAAA 
TGGAAGAAGG GTGTGAGCAA AGGAAACAAG TCTCTTGACG GCATGGAGTC CTATAATTTG 
CCATTTGGCA TGAACATTAT TAAAAAATAC AGATGCTTCA GCTACCTGCC TATCAGCCCA 
ACCTTTGCAG GTTACACATG GAAAGGCTTT GGGAAGAGTG AGAACAGGCG GAGTTCAGAC 
AAAGACTCCC AGGCCACAGT ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Slc23a2 ( XM_006235067.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006235129.1 Rattus norvegicus solute carrier family 23 member 2 (Slc23a2), transcript variant X2, mRNA.

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CloneID	ORa03628
Clone ID Related Accession (Same CDS sequence)	NM_017316.2 , XM_006235068.3 , XM_006235067.3
Accession Version	XM_006235067.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1944bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	solute carrier family 23 member 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006235067.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATGGGTG TCGGCAAGAA CACATCAAAG TCGGTGGAGG TTGGGGGCTC CACAGAAGGC 
AAATATGAAG AGGAGGCCAA GCGCCCCGAT TTCTTTACTC TCCCGGTGGT GATCAATGGT 
GGGGCCACGT CCAGTGGAGA ACAGGACAAT GAAGACACTG AGCTCATGGC CATCTACACC 
ACAGAGAATG GCATTGCAGA GAAGAGCTCT CTCGCAGAGA CCCTGGACAG CACTGGGAGC 
CTGGATCCCC AGAGGTCAGA TATGATCTAC ACTATAGAAG ACGTTCCTCC CTGGTACTTA 
TGCATATTCC TGGGGTTGCA GCACTACCTG ACGTGTTTCA GTGGCACAAT CGCAGTGCCC 
TTTTTGCTGG CTGATGCCAT GTGCGTGGGG GATGACCAGT GGGCCACCAG CCAGCTCATC 
GGGACCATTT TCTTCTGCGT GGGAATCACT ACATTGCTGC AGACAACATT TGGATGCAGG 
TTACCCCTGT TTCAGGCCAG TGCTTTTGCA TTTTTGGCCC CTGCTCGAGC CATCCTGTCT 
TTAGATAAAT GGAAATGTAA CACCACAGAG ATCACAGTTG CCAACGGAAC GGCAGAGCTG 
TTGGAACACA TCTGGCACCC CCGGATCCAA GAGATCCAGG GGGCTATAAT CATGTCCTCA 
CTGATAGAAG TGGTCATTGG CCTCCTTGGC CTGCCTGGGG CTCTGCTGAG GTATATTGGA 
CCCTTGACCA TCACACCCAC CGTGGCCCTC ATTGGCCTCT CTGGTTTCCA GGCAGCAGGA 
GAGCGAGCTG GGAAGCACTG GGGCATTGCC ATGCTGACAA TTTTCCTAGT GTTACTATTC 
TCACAATATG CCAGAAATGT TAAATTTCCT CTCCCAATCT ACAAATCCAA GAAAGGATGG 
ACGGCCTACA AGTTACAACT TTTCAAAATG TTTCCTATAA TCCTGGCTAT CCTCGTGTCC 
TGGCTGCTGT GCTTCATCTT CACGGTGACT GACGTCTTCC CTTCCAACAG CACCGACTAT 
GGCTACTATG CACGCACAGA TGCCAGGAAG GGCGTACTTC TGGTAGCCCC ATGGTTTAAG 
GTTCCATACC CATTTCAGTG GGGGATGCCC ACCGTCTCTG CAGCTGGCGT CATTGGCATG 
CTCAGTGCTG TCGTAGCCAG TATCATTGAG TCCATCGGCG ACTACTATGC CTGCGCCAGG 
CTCTCCTGTG CCCCACCACC TCCTATACAT GCAATAAACA GGGGTATTTT TGTGGAGGGT 
CTTTCTTGTG TTCTCGATGG CGTATTTGGT ACCGGGAATG GCTCTACCTC CTCCAGTCCC 
AATATTGGAG TTTTGGGAAT TACAAAGGTT GGCAGCCGCC GAGTGATCCA GTATGGTGCA 
GCTCTCATGC TGGGCTTGGG CATGATTGGC AAGTTCAGCG CCCTCTTCGC CTCCCTCCCA 
GACCCTGTAC TCGGAGCCCT CTTCTGCACA CTCTTTGGAA TGATCACAGC TGTTGGCCTC 
TCTAACCTGC AGTTCATTGA CTTGAATTCT TCCCGGAACC TATTTGTGCT TGGATTTTCC 
ATCTTCTTTG GGCTTGTTCT TCCAAGTTAC CTCAGACAAA ACCCTCTGGT TACAGGCATA 
ACAGGCATTG ATCAAGTTCT GAATGTCCTT CTCACCACTG CTATGTTCGT CGGAGGCTGT 
GTGGCTTTTA TTTTGGACAA CACCATCCCA GGAACCCCAG AGGAAAGAGG AATCAAGAAA 
TGGAAGAAGG GTGTGAGCAA AGGAAACAAG TCTCTTGACG GCATGGAGTC CTATAATTTG 
CCATTTGGCA TGAACATTAT TAAAAAATAC AGATGCTTCA GCTACCTGCC TATCAGCCCA 
ACCTTTGCAG GTTACACATG GAAAGGCTTT GGGAAGAGTG AGAACAGGCG GAGTTCAGAC 
AAAGACTCCC AGGCCACAGT ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006235129.1
CDS	1009..2952
Translation	MMGVGKNTSKSVEVGGSTEGKYEEEAKRPDFFTLPVVINGGATSSGEQDNEDTELMAIYTTENGIAEKSSLAETLDSTGSLDPQRSDMIYTIEDVPPWYLCIFLGLQHYLTCFSGTIAVPFLLADAMCVGDDQWATSQLIGTIFFCVGITTLLQTTFGCRLPLFQASAFAFLAPARAILSLDKWKCNTTEITVANGTAELLEHIWHPRIQEIQGAIIMSSLIEVVIGLLGLPGALLRYIGPLTITPTVALIGLSGFQAAGERAGKHWGIAMLTIFLVLLFSQYARNVKFPLPIYKSKKGWTAYKLQLFKMFPIILAILVSWLLCFIFTVTDVFPSNSTDYGYYARTDARKGVLLVAPWFKVPYPFQWGMPTVSAAGVIGMLSAVVASIIESIGDYYACARLSCAPPPPIHAINRGIFVEGLSCVLDGVFGTGNGSTSSSPNIGVLGITKVGSRRVIQYGAALMLGLGMIGKFSALFASLPDPVLGALFCTLFGMITAVGLSNLQFIDLNSSRNLFVLGFSIFFGLVLPSYLRQNPLVTGITGIDQVLNVLLTTAMFVGGCVAFILDNTIPGTPEERGIKKWKKGVSKGNKSLDGMESYNLPFGMNIIKKYRCFSYLPISPTFAGYTWKGFGKSENRRSSDKDSQATV

Target ORF information:

RefSeq Version	XM_006235067.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus solute carrier family 23 member 2 (Slc23a2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006235067.3

ORF Insert Sequence:

ATGATGGGTG TCGGCAAGAA CACATCAAAG TCGGTGGAGG TTGGGGGCTC CACAGAAGGC 
AAATATGAAG AGGAGGCCAA GCGCCCCGAT TTCTTTACTC TCCCGGTGGT GATCAATGGT 
GGGGCCACGT CCAGTGGAGA ACAGGACAAT GAAGACACTG AGCTCATGGC CATCTACACC 
ACAGAGAATG GCATTGCAGA GAAGAGCTCT CTCGCAGAGA CCCTGGACAG CACTGGGAGC 
CTGGATCCCC AGAGGTCAGA TATGATCTAC ACTATAGAAG ACGTTCCTCC CTGGTACTTA 
TGCATATTCC TGGGGTTGCA GCACTACCTG ACGTGTTTCA GTGGCACAAT CGCAGTGCCC 
TTTTTGCTGG CTGATGCCAT GTGCGTGGGG GATGACCAGT GGGCCACCAG CCAGCTCATC 
GGGACCATTT TCTTCTGCGT GGGAATCACT ACATTGCTGC AGACAACATT TGGATGCAGG 
TTACCCCTGT TTCAGGCCAG TGCTTTTGCA TTTTTGGCCC CTGCTCGAGC CATCCTGTCT 
TTAGATAAAT GGAAATGTAA CACCACAGAG ATCACAGTTG CCAACGGAAC GGCAGAGCTG 
TTGGAACACA TCTGGCACCC CCGGATCCAA GAGATCCAGG GGGCTATAAT CATGTCCTCA 
CTGATAGAAG TGGTCATTGG CCTCCTTGGC CTGCCTGGGG CTCTGCTGAG GTATATTGGA 
CCCTTGACCA TCACACCCAC CGTGGCCCTC ATTGGCCTCT CTGGTTTCCA GGCAGCAGGA 
GAGCGAGCTG GGAAGCACTG GGGCATTGCC ATGCTGACAA TTTTCCTAGT GTTACTATTC 
TCACAATATG CCAGAAATGT TAAATTTCCT CTCCCAATCT ACAAATCCAA GAAAGGATGG 
ACGGCCTACA AGTTACAACT TTTCAAAATG TTTCCTATAA TCCTGGCTAT CCTCGTGTCC 
TGGCTGCTGT GCTTCATCTT CACGGTGACT GACGTCTTCC CTTCCAACAG CACCGACTAT 
GGCTACTATG CACGCACAGA TGCCAGGAAG GGCGTACTTC TGGTAGCCCC ATGGTTTAAG 
GTTCCATACC CATTTCAGTG GGGGATGCCC ACCGTCTCTG CAGCTGGCGT CATTGGCATG 
CTCAGTGCTG TCGTAGCCAG TATCATTGAG TCCATCGGCG ACTACTATGC CTGCGCCAGG 
CTCTCCTGTG CCCCACCACC TCCTATACAT GCAATAAACA GGGGTATTTT TGTGGAGGGT 
CTTTCTTGTG TTCTCGATGG CGTATTTGGT ACCGGGAATG GCTCTACCTC CTCCAGTCCC 
AATATTGGAG TTTTGGGAAT TACAAAGGTT GGCAGCCGCC GAGTGATCCA GTATGGTGCA 
GCTCTCATGC TGGGCTTGGG CATGATTGGC AAGTTCAGCG CCCTCTTCGC CTCCCTCCCA 
GACCCTGTAC TCGGAGCCCT CTTCTGCACA CTCTTTGGAA TGATCACAGC TGTTGGCCTC 
TCTAACCTGC AGTTCATTGA CTTGAATTCT TCCCGGAACC TATTTGTGCT TGGATTTTCC 
ATCTTCTTTG GGCTTGTTCT TCCAAGTTAC CTCAGACAAA ACCCTCTGGT TACAGGCATA 
ACAGGCATTG ATCAAGTTCT GAATGTCCTT CTCACCACTG CTATGTTCGT CGGAGGCTGT 
GTGGCTTTTA TTTTGGACAA CACCATCCCA GGAACCCCAG AGGAAAGAGG AATCAAGAAA 
TGGAAGAAGG GTGTGAGCAA AGGAAACAAG TCTCTTGACG GCATGGAGTC CTATAATTTG 
CCATTTGGCA TGAACATTAT TAAAAAATAC AGATGCTTCA GCTACCTGCC TATCAGCCCA 
ACCTTTGCAG GTTACACATG GAAAGGCTTT GGGAAGAGTG AGAACAGGCG GAGTTCAGAC 
AAAGACTCCC AGGCCACAGT ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Slc23a2 ( XM_006235069.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006235131.1 Rattus norvegicus solute carrier family 23 member 2 (Slc23a2), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa26417
Clone ID Related Accession (Same CDS sequence)	XM_006235069.2
Accession Version	XM_006235069.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1794bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	solute carrier family 23 member 2 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 7, 2014 this sequence version replaced XM_006235069.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGGCAAT ATCATGGGAG TCAGAGCCCT CATTCTGAGA ATTATCTCTT TGAGAGCTCT 
CTCGCAGAGA CCCTGGACAG CACTGGGAGC CTGGATCCCC AGAGGTCAGA TATGATCTAC 
ACTATAGAAG ACGTTCCTCC CTGGTACTTA TGCATATTCC TGGGGTTGCA GCACTACCTG 
ACGTGTTTCA GTGGCACAAT CGCAGTGCCC TTTTTGCTGG CTGATGCCAT GTGCGTGGGG 
GATGACCAGT GGGCCACCAG CCAGCTCATC GGGACCATTT TCTTCTGCGT GGGAATCACT 
ACATTGCTGC AGACAACATT TGGATGCAGG TTACCCCTGT TTCAGGCCAG TGCTTTTGCA 
TTTTTGGCCC CTGCTCGAGC CATCCTGTCT TTAGATAAAT GGAAATGTAA CACCACAGAG 
ATCACAGTTG CCAACGGAAC GGCAGAGCTG TTGGAACACA TCTGGCACCC CCGGATCCAA 
GAGATCCAGG GGGCTATAAT CATGTCCTCA CTGATAGAAG TGGTCATTGG CCTCCTTGGC 
CTGCCTGGGG CTCTGCTGAG GTATATTGGA CCCTTGACCA TCACACCCAC CGTGGCCCTC 
ATTGGCCTCT CTGGTTTCCA GGCAGCAGGA GAGCGAGCTG GGAAGCACTG GGGCATTGCC 
ATGCTGACAA TTTTCCTAGT GTTACTATTC TCACAATATG CCAGAAATGT TAAATTTCCT 
CTCCCAATCT ACAAATCCAA GAAAGGATGG ACGGCCTACA AGTTACAACT TTTCAAAATG 
TTTCCTATAA TCCTGGCTAT CCTCGTGTCC TGGCTGCTGT GCTTCATCTT CACGGTGACT 
GACGTCTTCC CTTCCAACAG CACCGACTAT GGCTACTATG CACGCACAGA TGCCAGGAAG 
GGCGTACTTC TGGTAGCCCC ATGGTTTAAG GTTCCATACC CATTTCAGTG GGGGATGCCC 
ACCGTCTCTG CAGCTGGCGT CATTGGCATG CTCAGTGCTG TCGTAGCCAG TATCATTGAG 
TCCATCGGCG ACTACTATGC CTGCGCCAGG CTCTCCTGTG CCCCACCACC TCCTATACAT 
GCAATAAACA GGGGTATTTT TGTGGAGGGT CTTTCTTGTG TTCTCGATGG CGTATTTGGT 
ACCGGGAATG GCTCTACCTC CTCCAGTCCC AATATTGGAG TTTTGGGAAT TACAAAGGTT 
GGCAGCCGCC GAGTGATCCA GTATGGTGCA GCTCTCATGC TGGGCTTGGG CATGATTGGC 
AAGTTCAGCG CCCTCTTCGC CTCCCTCCCA GACCCTGTAC TCGGAGCCCT CTTCTGCACA 
CTCTTTGGAA TGATCACAGC TGTTGGCCTC TCTAACCTGC AGTTCATTGA CTTGAATTCT 
TCCCGGAACC TATTTGTGCT TGGATTTTCC ATCTTCTTTG GGCTTGTTCT TCCAAGTTAC 
CTCAGACAAA ACCCTCTGGT TACAGGCATA ACAGGCATTG ATCAAGTTCT GAATGTCCTT 
CTCACCACTG CTATGTTCGT CGGAGGCTGT GTGGCTTTTA TTTTGGACAA CACCATCCCA 
GGAACCCCAG AGGAAAGAGG AATCAAGAAA TGGAAGAAGG GTGTGAGCAA AGGAAACAAG 
TCTCTTGACG GCATGGAGTC CTATAATTTG CCATTTGGCA TGAACATTAT TAAAAAATAC 
AGATGCTTCA GCTACCTGCC TATCAGCCCA ACCTTTGCAG GTTACACATG GAAAGGCTTT 
GGGAAGAGTG AGAACAGGCG GAGTTCAGAC AAAGACTCCC AGGCCACAGT ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006235131.1
CDS	2603..4396
Translation	MRQYHGSQSPHSENYLFESSLAETLDSTGSLDPQRSDMIYTIEDVPPWYLCIFLGLQHYLTCFSGTIAVPFLLADAMCVGDDQWATSQLIGTIFFCVGITTLLQTTFGCRLPLFQASAFAFLAPARAILSLDKWKCNTTEITVANGTAELLEHIWHPRIQEIQGAIIMSSLIEVVIGLLGLPGALLRYIGPLTITPTVALIGLSGFQAAGERAGKHWGIAMLTIFLVLLFSQYARNVKFPLPIYKSKKGWTAYKLQLFKMFPIILAILVSWLLCFIFTVTDVFPSNSTDYGYYARTDARKGVLLVAPWFKVPYPFQWGMPTVSAAGVIGMLSAVVASIIESIGDYYACARLSCAPPPPIHAINRGIFVEGLSCVLDGVFGTGNGSTSSSPNIGVLGITKVGSRRVIQYGAALMLGLGMIGKFSALFASLPDPVLGALFCTLFGMITAVGLSNLQFIDLNSSRNLFVLGFSIFFGLVLPSYLRQNPLVTGITGIDQVLNVLLTTAMFVGGCVAFILDNTIPGTPEERGIKKWKKGVSKGNKSLDGMESYNLPFGMNIIKKYRCFSYLPISPTFAGYTWKGFGKSENRRSSDKDSQATV

Target ORF information:

RefSeq Version	XM_006235069.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus solute carrier family 23 member 2 (Slc23a2), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006235069.2

ORF Insert Sequence:

ATGAGGCAAT ATCATGGGAG TCAGAGCCCT CATTCTGAGA ATTATCTCTT TGAGAGCTCT 
CTCGCAGAGA CCCTGGACAG CACTGGGAGC CTGGATCCCC AGAGGTCAGA TATGATCTAC 
ACTATAGAAG ACGTTCCTCC CTGGTACTTA TGCATATTCC TGGGGTTGCA GCACTACCTG 
ACGTGTTTCA GTGGCACAAT CGCAGTGCCC TTTTTGCTGG CTGATGCCAT GTGCGTGGGG 
GATGACCAGT GGGCCACCAG CCAGCTCATC GGGACCATTT TCTTCTGCGT GGGAATCACT 
ACATTGCTGC AGACAACATT TGGATGCAGG TTACCCCTGT TTCAGGCCAG TGCTTTTGCA 
TTTTTGGCCC CTGCTCGAGC CATCCTGTCT TTAGATAAAT GGAAATGTAA CACCACAGAG 
ATCACAGTTG CCAACGGAAC GGCAGAGCTG TTGGAACACA TCTGGCACCC CCGGATCCAA 
GAGATCCAGG GGGCTATAAT CATGTCCTCA CTGATAGAAG TGGTCATTGG CCTCCTTGGC 
CTGCCTGGGG CTCTGCTGAG GTATATTGGA CCCTTGACCA TCACACCCAC CGTGGCCCTC 
ATTGGCCTCT CTGGTTTCCA GGCAGCAGGA GAGCGAGCTG GGAAGCACTG GGGCATTGCC 
ATGCTGACAA TTTTCCTAGT GTTACTATTC TCACAATATG CCAGAAATGT TAAATTTCCT 
CTCCCAATCT ACAAATCCAA GAAAGGATGG ACGGCCTACA AGTTACAACT TTTCAAAATG 
TTTCCTATAA TCCTGGCTAT CCTCGTGTCC TGGCTGCTGT GCTTCATCTT CACGGTGACT 
GACGTCTTCC CTTCCAACAG CACCGACTAT GGCTACTATG CACGCACAGA TGCCAGGAAG 
GGCGTACTTC TGGTAGCCCC ATGGTTTAAG GTTCCATACC CATTTCAGTG GGGGATGCCC 
ACCGTCTCTG CAGCTGGCGT CATTGGCATG CTCAGTGCTG TCGTAGCCAG TATCATTGAG 
TCCATCGGCG ACTACTATGC CTGCGCCAGG CTCTCCTGTG CCCCACCACC TCCTATACAT 
GCAATAAACA GGGGTATTTT TGTGGAGGGT CTTTCTTGTG TTCTCGATGG CGTATTTGGT 
ACCGGGAATG GCTCTACCTC CTCCAGTCCC AATATTGGAG TTTTGGGAAT TACAAAGGTT 
GGCAGCCGCC GAGTGATCCA GTATGGTGCA GCTCTCATGC TGGGCTTGGG CATGATTGGC 
AAGTTCAGCG CCCTCTTCGC CTCCCTCCCA GACCCTGTAC TCGGAGCCCT CTTCTGCACA 
CTCTTTGGAA TGATCACAGC TGTTGGCCTC TCTAACCTGC AGTTCATTGA CTTGAATTCT 
TCCCGGAACC TATTTGTGCT TGGATTTTCC ATCTTCTTTG GGCTTGTTCT TCCAAGTTAC 
CTCAGACAAA ACCCTCTGGT TACAGGCATA ACAGGCATTG ATCAAGTTCT GAATGTCCTT 
CTCACCACTG CTATGTTCGT CGGAGGCTGT GTGGCTTTTA TTTTGGACAA CACCATCCCA 
GGAACCCCAG AGGAAAGAGG AATCAAGAAA TGGAAGAAGG GTGTGAGCAA AGGAAACAAG 
TCTCTTGACG GCATGGAGTC CTATAATTTG CCATTTGGCA TGAACATTAT TAAAAAATAC 
AGATGCTTCA GCTACCTGCC TATCAGCCCA ACCTTTGCAG GTTACACATG GAAAGGCTTT 
GGGAAGAGTG AGAACAGGCG GAGTTCAGAC AAAGACTCCC AGGCCACAGT ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

SVCT2 Expression and Function in Reactive Astrocytes Is a Common Event in Different Brain Pathologies.
Molecular neurobiology(2017 Sep)
Salazar K,Mart?nez F,P?rez-Mart?n M,Cifuentes M,Trigueros L,Ferrada L,Espinoza F,Saldivia N,Bertinat R,Forman K,Oviedo MJ,L?pez-Gambero AJ,Bonansco C,Bongarzone ER,Nualart F

SVCT2, a potential therapeutic target, protects against oxidative stress during ethanol-induced neurotoxicity via JNK/p38 MAPKs, NF-?B and miRNA125a-5p.
Free radical biology & medicine96362-73(2016 07)
Tian H,Ye X,Hou X,Yang X,Yang J,Wu C

Orally administrated ascorbic acid suppresses neuronal damage and modifies expression of SVCT2 and GLUT1 in the brain of diabetic rats with cerebral ischemia-reperfusion.
Nutrients6(4)1554-77(2014 Apr)
Iwata N,Okazaki M,Xuan M,Kamiuchi S,Matsuzaki H,Hibino Y

Liver metabolic/oxidative stress induces hepatic and extrahepatic changes in the expression of the vitamin C transporters SVCT1 and SVCT2.
European journal of nutrition53(2)401-12(2014)
Hierro C,Monte MJ,Lozano E,Gonzalez-Sanchez E,Marin JJ,Macias RI

Downregulation of vitamin C transporter SVCT-2 in doxorubicin-induced cardiomyocyte injury.
American journal of physiology. Cell physiology303(6)C645-53(2012 Sep)
Ludke AR,Sharma AK,Akolkar G,Bajpai G,Singal PK

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Slc23a2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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