Eml1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Eml1
Entrez Gene ID	362783
Full Name	echinoderm microtubule associated protein like 1
General protein information	Preferred Names echinoderm microtubule associated protein like 1 Names echinoderm microtubule-associated protein-like 1 EMAP-1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 6 Map Location: 6q32

mRNA and Protein(s)

mRNA	Protein	Name
NM_001025741.1	NP_001020912.1	echinoderm microtubule-associated protein-like 1

Pathways from BioSystems

Homologies

	EML1	XP_001103795.2
Pan troglodytes (chimpanzee)	EML1	XP_001157076.2
Mus musculus (house mouse)	Eml1	NP_001036800.1
Gallus gallus (chicken)	EML1	XP_004936364.1
Homo sapiens (human)	EML1	NP_001008707.1
Xenopus tropicalis (tropical clawed frog)	LOC100495318	XP_002936629.1
Canis lupus familiaris (dog)	EML1	XP_005623850.1
Bos taurus (cattle)	EML1	XP_002696814.2
Rattus norvegicus (Norway rat)	Eml1	NP_001020912.1
Danio rerio (zebrafish)	eml1	NP_001180527.1

Gene Ontology
Bibliography

Related articles in PubMed

Mutations in Eml1 lead to ectopic progenitors and neuronal heterotopia in mouse and human.
Kielar M, Tuy FP, Bizzotto S, Lebrand C, de Juan Romero C, Poirier K, Oegema R, Mancini GM, Bahi-Buisson N, Olaso R, Le Moing AG, Boutourlinsky K, Boucher D, Carpentier W, Berquin P, Deleuze JF, Belvindrah R, Borrell V, Welker E, Chelly J, Croquelois A, Francis F
Nature neuroscience17(7)923-33(2014 Jul)

Crystal structure of EML1 reveals the basis for Hsp90 dependence of oncogenic EML4-ALK by disruption of an atypical ?-propeller domain.
Richards MW, Law EW, Rennalls LP, Busacca S, O'Regan L, Fry AM, Fennell DA, Bayliss R
Proceedings of the National Academy of Sciences of the United States of America111(14)5195-200(2014 Apr)

Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7.
Nagamachi A, Matsui H, Asou H, Ozaki Y, Aki D, Kanai A, Takubo K, Suda T, Nakamura T, Wolff L, Honda H, Inaba T
Cancer cell24(3)305-17(2013 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Eml1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Eml1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa07922	NM_001025741.1 Latest version!	Rattus norvegicus EMAP like 1 (Eml1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$391.30 $559.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Eml1 ( NM_001025741.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001020912.1 Rattus norvegicus EMAP like 1 (Eml1), mRNA.

Price & Availability↑

CloneID	ORa07922
Clone ID Related Accession (Same CDS sequence)	NM_001025741.1
Accession Version	NM_001025741.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2352bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-12-12
Organism	Rattus norvegicus(Norway rat)
Product	echinoderm microtubule-associated protein-like 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC097450.1. On Jul 22, 2005 this sequence version replaced XM_343109.2. ##Evidence-Data-START## Transcript exon combination :: BC097450.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMEA2689604 [ECO:0000350] ##Evidence-Data-END##

ATGGAGATAT CAGACCGCAT CGCCTCTCTG GAGCAGCGGG TCCAGATGCA GGAGGATGAC 
ATTCAGCTGC TCAAGTCGGC GCTGGCCGAC GTGGTTCGGA GGCTGAACAT CACAGAGGAG 
CAACAGGCTG TCCTTAACAG GAAAGGACCT ACCAAAGCGA GACCACTGGG GCAGACCCTG 
CCACTTAGAA CCACCGTCAA CAATGGCACC GTGTTACCAA AGAAACCCAG TGCTTCCCTC 
CCATCGCCCT CGGGGTCCAG GAAAGAAATG GTTGTGCCGG TAACCAAAAG CATCAACAGG 
ACCAGCTCTT CCGAACGAGT GTCTCCAGGC GGCCGGAGGG AGAGCTCCGG GGACTCCAAA 
GGAAGCCGGA ACCGCACCGG CTCTACCAGC AGCTCGTCCA GCGGCAAGAA GAACAGTGAG 
AGCAAACCCA AGGAGCCTAC ATTCAGTCCA GAAGAGGGGT ATGTAAAAAT GTTTCTTCGA 
GGCCGCCCCG TCACCATGTA CATGCCCAAA GACCAAGTGG ATTCCTACAG TTTGGAAGCG 
AAAGCTGAAT TGCCAACGAA ACGGCTGAAG CTGGAGTGGG TCTACGGGTA CCGGGGGCGA 
GACTGTCGTA ATAACCTGTA CCTGCTCCCG ACCGGGGAGA CGGTGTACTT CATAGCGTCG 
GTTGTGGTGC TTTACAACGT GGAGGAACAG CTGCAGAGGC ATTACGCGGG CCACAACGAC 
GACGTCAAGT GCCTAGCGGT CCACCCTGAC AGAATCACCA TAGCAACAGG ACAAGTGGCG 
GGCACATCTA AAGATGGAAA GCAACTGCCG CCACACGTGC GTATCTGGGA CTCTGTGACC 
CTGAACACTC TGCATGTCAT CGGAATAGGC TTTTTTGACC GGGCTGTCAC CTGCATCGCA 
TTCTCAAAAT CCAACGGAGG AAGCCACCTC TGTGCTGTGG ATGACTCCAA TGACCATGTG 
TTGTCTGTGT GGGACTGGCA GAGAGAGGAG AGGCTGGCTG ACGTGAAGTG TTCGAACGAA 
GCGGTATTTG CTGCGGACTT CCACCCCACA GACACCAATA TCATAGTCAC CTGCGGGAAG 
TCACATCTCT ACTTTTGGAC CCTAGAAGGA AATTCCCTTA ACAAGAAGCA AGGGTTGTTT 
GAGAAACAAG AGAAGCCAAA GTTTGTCCTT TGCGTGACGT TTTCTGAAAA TGGCGACACC 
ATTACTGGAG ATTCAAGTGG CAACATCTTG GTGTGGGGAA AAGGTACAAA TCGAATAAGC 
TATGCAGTTC AAGGGGCCCA CGAGGGCGGC ATTTTTGCAC TTTGTATGCT GAGAGATGGC 
ACGCTGGTGT CCGGAGGAGG GAAGGACCGG CGCCTCATTT CCTGGAACGG AAACTATCAA 
AAACTTCACA AAGCAGAGAT TCCTGAGCAG TTTGGCCCAA TACGGACAGT GGCTGAGGGG 
AAGGGCAATG TCATCTTGAT TGGCACTACT AGAAACTTTG TCCTGCAAGG CACCTTGACC 
GGGGACTTCA CACCCATCAC TCAGGGTCAC ACTGATGAGC TCTGGGGGCT GGCCATCCAT 
GCCTCCAAAC CTCAGTTCTT GACCTGTGGA CATGACAAGC ACGCCACTCT CTGGGACGCC 
GTTGGTCACC GGCCAGTCTG GGACAAAATC ATAGAGGATC CAGCTCAGTC CTCTGGTTTT 
CATCCTTCAG GGTCTGTGGT TGCAGTCGGG ACCCTGACTG GGAGGTGGTT TGTGTTTGAC 
ACGGAAACGA AGGACCTGGT CACCGTCCAC ACGGATGGGA ATGAGCAGCT CTCCGTGATG 
CGGTATTCTC CAGATGGGAA CTTCCTGGCA ATCGGCTCCC ATGACAACTG CATCTACATA 
TACGGAGTCA GCGACAATGG AAGGAAGTAC ACGCGAGTTG GCAAGTGCTC CGGCCATTCC 
AGCTTCATCA CCCACTTGGA CTGGTCCGTG AACTCACAAT TCCTGGTGTC AAATTCCGGG 
GACTACGAGA TCCTCTACTG GGTCCCATCT GCCTGTAAGC AAGTCGTGAG TGTGGAAACC 
ACACGGGACA TCGAGTGGGC CACCTATACC TGCACCTTGG GATTCCATGT CTTTGGAGTG 
TGGCCTGAGG GCTCAGATGG AACAGACATC AATGCTGTCT GCCGGGCCCA CGAGAAAAAG 
CTCCTGTCCA CAGGCGATGA CTTCGGCAAA GTGCACCTCT TCTCATACCC ATGCTCACAG 
TTCAGGGCTC CGAGCCACAT CTACAGTGGA CACAGCAGCC ACGTCACCAA CGTAGACTTC 
CTCTGTGAAG ACAGCCACCT TATCTCCACG GGTGGGAAAG ACACAAGCAT CATGCAGTGG 
CGGGTCATTT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001020912.1
CDS	136..2487
Translation	MEISDRIASLEQRVQMQEDDIQLLKSALADVVRRLNITEEQQAVLNRKGPTKARPLGQTLPLRTTVNNGTVLPKKPSASLPSPSGSRKEMVVPVTKSINRTSSSERVSPGGRRESSGDSKGSRNRTGSTSSSSSGKKNSESKPKEPTFSPEEGYVKMFLRGRPVTMYMPKDQVDSYSLEAKAELPTKRLKLEWVYGYRGRDCRNNLYLLPTGETVYFIASVVVLYNVEEQLQRHYAGHNDDVKCLAVHPDRITIATGQVAGTSKDGKQLPPHVRIWDSVTLNTLHVIGIGFFDRAVTCIAFSKSNGGSHLCAVDDSNDHVLSVWDWQREERLADVKCSNEAVFAADFHPTDTNIIVTCGKSHLYFWTLEGNSLNKKQGLFEKQEKPKFVLCVTFSENGDTITGDSSGNILVWGKGTNRISYAVQGAHEGGIFALCMLRDGTLVSGGGKDRRLISWNGNYQKLHKAEIPEQFGPIRTVAEGKGNVILIGTTRNFVLQGTLTGDFTPITQGHTDELWGLAIHASKPQFLTCGHDKHATLWDAVGHRPVWDKIIEDPAQSSGFHPSGSVVAVGTLTGRWFVFDTETKDLVTVHTDGNEQLSVMRYSPDGNFLAIGSHDNCIYIYGVSDNGRKYTRVGKCSGHSSFITHLDWSVNSQFLVSNSGDYEILYWVPSACKQVVSVETTRDIEWATYTCTLGFHVFGVWPEGSDGTDINAVCRAHEKKLLSTGDDFGKVHLFSYPCSQFRAPSHIYSGHSSHVTNVDFLCEDSHLISTGGKDTSIMQWRVI

Target ORF information:

RefSeq Version	NM_001025741.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus EMAP like 1 (Eml1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001025741.1

ORF Insert Sequence:

ATGGAGATAT CAGACCGCAT CGCCTCTCTG GAGCAGCGGG TCCAGATGCA GGAGGATGAC 
ATTCAGCTGC TCAAGTCGGC GCTGGCCGAC GTGGTTCGGA GGCTGAACAT CACAGAGGAG 
CAACAGGCTG TCCTTAACAG GAAAGGACCT ACCAAAGCGA GACCACTGGG GCAGACCCTG 
CCACTTAGAA CCACCGTCAA CAATGGCACC GTGTTACCAA AGAAACCCAG TGCTTCCCTC 
CCATCGCCCT CGGGGTCCAG GAAAGAAATG GTTGTGCCGG TAACCAAAAG CATCAACAGG 
ACCAGCTCTT CCGAACGAGT GTCTCCAGGC GGCCGGAGGG AGAGCTCCGG GGACTCCAAA 
GGAAGCCGGA ACCGCACCGG CTCTACCAGC AGCTCGTCCA GCGGCAAGAA GAACAGTGAG 
AGCAAACCCA AGGAGCCTAC ATTCAGTCCA GAAGAGGGGT ATGTAAAAAT GTTTCTTCGA 
GGCCGCCCCG TCACCATGTA CATGCCCAAA GACCAAGTGG ATTCCTACAG TTTGGAAGCG 
AAAGCTGAAT TGCCAACGAA ACGGCTGAAG CTGGAGTGGG TCTACGGGTA CCGGGGGCGA 
GACTGTCGTA ATAACCTGTA CCTGCTCCCG ACCGGGGAGA CGGTGTACTT CATAGCGTCG 
GTTGTGGTGC TTTACAACGT GGAGGAACAG CTGCAGAGGC ATTACGCGGG CCACAACGAC 
GACGTCAAGT GCCTAGCGGT CCACCCTGAC AGAATCACCA TAGCAACAGG ACAAGTGGCG 
GGCACATCTA AAGATGGAAA GCAACTGCCG CCACACGTGC GTATCTGGGA CTCTGTGACC 
CTGAACACTC TGCATGTCAT CGGAATAGGC TTTTTTGACC GGGCTGTCAC CTGCATCGCA 
TTCTCAAAAT CCAACGGAGG AAGCCACCTC TGTGCTGTGG ATGACTCCAA TGACCATGTG 
TTGTCTGTGT GGGACTGGCA GAGAGAGGAG AGGCTGGCTG ACGTGAAGTG TTCGAACGAA 
GCGGTATTTG CTGCGGACTT CCACCCCACA GACACCAATA TCATAGTCAC CTGCGGGAAG 
TCACATCTCT ACTTTTGGAC CCTAGAAGGA AATTCCCTTA ACAAGAAGCA AGGGTTGTTT 
GAGAAACAAG AGAAGCCAAA GTTTGTCCTT TGCGTGACGT TTTCTGAAAA TGGCGACACC 
ATTACTGGAG ATTCAAGTGG CAACATCTTG GTGTGGGGAA AAGGTACAAA TCGAATAAGC 
TATGCAGTTC AAGGGGCCCA CGAGGGCGGC ATTTTTGCAC TTTGTATGCT GAGAGATGGC 
ACGCTGGTGT CCGGAGGAGG GAAGGACCGG CGCCTCATTT CCTGGAACGG AAACTATCAA 
AAACTTCACA AAGCAGAGAT TCCTGAGCAG TTTGGCCCAA TACGGACAGT GGCTGAGGGG 
AAGGGCAATG TCATCTTGAT TGGCACTACT AGAAACTTTG TCCTGCAAGG CACCTTGACC 
GGGGACTTCA CACCCATCAC TCAGGGTCAC ACTGATGAGC TCTGGGGGCT GGCCATCCAT 
GCCTCCAAAC CTCAGTTCTT GACCTGTGGA CATGACAAGC ACGCCACTCT CTGGGACGCC 
GTTGGTCACC GGCCAGTCTG GGACAAAATC ATAGAGGATC CAGCTCAGTC CTCTGGTTTT 
CATCCTTCAG GGTCTGTGGT TGCAGTCGGG ACCCTGACTG GGAGGTGGTT TGTGTTTGAC 
ACGGAAACGA AGGACCTGGT CACCGTCCAC ACGGATGGGA ATGAGCAGCT CTCCGTGATG 
CGGTATTCTC CAGATGGGAA CTTCCTGGCA ATCGGCTCCC ATGACAACTG CATCTACATA 
TACGGAGTCA GCGACAATGG AAGGAAGTAC ACGCGAGTTG GCAAGTGCTC CGGCCATTCC 
AGCTTCATCA CCCACTTGGA CTGGTCCGTG AACTCACAAT TCCTGGTGTC AAATTCCGGG 
GACTACGAGA TCCTCTACTG GGTCCCATCT GCCTGTAAGC AAGTCGTGAG TGTGGAAACC 
ACACGGGACA TCGAGTGGGC CACCTATACC TGCACCTTGG GATTCCATGT CTTTGGAGTG 
TGGCCTGAGG GCTCAGATGG AACAGACATC AATGCTGTCT GCCGGGCCCA CGAGAAAAAG 
CTCCTGTCCA CAGGCGATGA CTTCGGCAAA GTGCACCTCT TCTCATACCC ATGCTCACAG 
TTCAGGGCTC CGAGCCACAT CTACAGTGGA CACAGCAGCC ACGTCACCAA CGTAGACTTC 
CTCTGTGAAG ACAGCCACCT TATCTCCACG GGTGGGAAAG ACACAAGCAT CATGCAGTGG 
CGGGTCATTT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Mutations in Eml1 lead to ectopic progenitors and neuronal heterotopia in mouse and human.
Nature neuroscience17(7)923-33(2014 Jul)
Kielar M,Tuy FP,Bizzotto S,Lebrand C,de Juan Romero C,Poirier K,Oegema R,Mancini GM,Bahi-Buisson N,Olaso R,Le Moing AG,Boutourlinsky K,Boucher D,Carpentier W,Berquin P,Deleuze JF,Belvindrah R,Borrell V,Welker E,Chelly J,Croquelois A,Francis F

Crystal structure of EML1 reveals the basis for Hsp90 dependence of oncogenic EML4-ALK by disruption of an atypical ?-propeller domain.
Proceedings of the National Academy of Sciences of the United States of America111(14)5195-200(2014 Apr)
Richards MW,Law EW,Rennalls LP,Busacca S,O'Regan L,Fry AM,Fennell DA,Bayliss R

Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7.
Cancer cell24(3)305-17(2013 Sep)
Nagamachi A,Matsui H,Asou H,Ozaki Y,Aki D,Kanai A,Takubo K,Suda T,Nakamura T,Wolff L,Honda H,Inaba T

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Eml1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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