Clec4a3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Clec4a3
Entrez Gene ID	362431
Full Name	C-type lectin domain family 4, member A3
Synonyms	Dcir3
General protein information	Preferred Names C-type lectin domain family 4, member A3 Names C-type lectin domain family 4, member A3 antigen-presenting cell lectin-like receptor complex APLEC dendritic cell inhibitory receptor 3
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 4 Map Location: 4q42

mRNA and Protein(s)

mRNA	Protein	Name
NM_001005891.1	NP_001005891.1	C-type lectin domain family 4, member A3

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Clec4a3	NP_001191170.1
Rattus norvegicus (Norway rat)	Clec4a3	NP_001005891.1

Gene Ontology
Bibliography

Related articles in PubMed

Crystal structure of human dendritic cell inhibitory receptor C-type lectin domain reveals the binding mode with N-glycan.
Nagae M, Ikeda A, Hanashima S, Kojima T, Matsumoto N, Yamamoto K, Yamaguchi Y
FEBS letters590(8)1280-8(2016 04)

Cross-priming CD8+ T cells by targeting antigens to human dendritic cells through DCIR.
Klechevsky E, Flamar AL, Cao Y, Blanck JP, Liu M, O'Bar A, Agouna-Deciat O, Klucar P, Thompson-Snipes L, Zurawski S, Reiter Y, Palucka AK, Zurawski G, Banchereau J
Blood116(10)1685-97(2010 Sep)

The rat antigen-presenting lectin-like receptor complex influences innate immunity and development of infectious diseases.
Guo JP, Verdrengh M, Tarkowski A, Lange S, Jennische E, Lorentzen JC, Harris RA
Genes and immunity10(3)227-36(2009 Apr)

Targeting DCIR on human plasmacytoid dendritic cells results in antigen presentation and inhibits IFN-alpha production.
Meyer-Wentrup F, Benitez-Ribas D, Tacken PJ, Punt CJ, Figdor CG, de Vries IJ, Adema GJ
Blood111(8)4245-53(2008 Apr)

Association of arthritis with a gene complex encoding C-type lectin-like receptors.
Lorentzen JC, Flornes L, Ekl?w C, B?ckdahl L, Ribbhammar U, Guo JP, Smolnikova M, Dissen E, Seddighzadeh M, Brookes AJ, Alfredsson L, Klareskog L, Padyukov L, Fossum S
Arthritis and rheumatism56(8)2620-32(2007 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

APLEC influences innate immunity and responses to infectious agents.
Title: The rat antigen-presenting lectin-like receptor complex influences innate immunity and development of infectious diseases.

Rat APLEC is associated with susceptibility to polyarthritis.
Title: Association of arthritis with a gene complex encoding C-type lectin-like receptors.

The following Clec4a3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Clec4a3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa10830	NM_001005891.1 Latest version!	Rattus norvegicus C-type lectin domain family 4, member A3 (Clec4a3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Clec4a3 ( NM_001005891.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001005891.1 Rattus norvegicus C-type lectin domain family 4, member A3 (Clec4a3), mRNA.

Price & Availability↑

CloneID	ORa10830
Clone ID Related Accession (Same CDS sequence)	NM_001005891.1
Accession Version	NM_001005891.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 714bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-18
Organism	Rattus norvegicus(Norway rat)
Product	C-type lectin domain family 4, member A3
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY397671.1. On Oct 22, 2004 this sequence version replaced XM_342752.1. ##Evidence-Data-START## Transcript exon combination :: AY397671.1, FQ230051.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01906353, SAMN01906354 [ECO:0000348] ##Evidence-Data-END##

ATGTTTTCAG AAAACATTTA TATTAACACG AACTTCAAAA ATAAATATGA CTCCTCAGAC 
ATCGACACAG ACTTTCGGCC AGATCCCCCA AAGAAGAGCA AGTCTCAGAA AAGTTGCCAC 
AAGTTCTCCA AGGTCCTCTT TACCTCACTC ATAATCTATT TCCTGCTGTT GACAATCTTA 
TTCTCCAGTG CTCTGATCAT TCTGTTTAAA AAATATTCTC AGCTTCTGGA AGAAAAAACA 
ATTATGAAGG AACTGAACTA TACTGAATTG GAGTGTACAA AATGGGATTC ACTCTTGGAA 
GACAAAGTCT GGAGCTGTTG CCCAAAGGAT TGGAAGCCAT TTGATTCCAA CTGCTACTTC 
CCTTCCACTG ACTCAGTAGA ATCTTGGATG GAGAGTGAGG AGAAGTGCTC CGGCATAGGT 
GCTCATCTGG TGGTGATCCA CAGCCAGGAA GAGCAGGATT TCCTGCCCAG GATCCTGGAT 
ACTCATGCTG CTTATTTTAT AGGACTTTCA GATCCAGGTC ATCGACAATG GCAATGGGTC 
GATCAGACAC CATACAATGG GAATGCCACA TTCTGGCATG AAGGTGAGCC CAGCAGTGAC 
AATGAACAAT GTGTTATAAT AAATCATCAT GAGAATACTG GATGGGGCTG GAGTGATAGC 
TCTTGCAGTG ATAAACAGAA GTTGGTTTGT CAGGTGAAAA AAATATACTT ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001005891.1
CDS	34..747
Translation	MFSENIYINTNFKNKYDSSDIDTDFRPDPPKKSKSQKSCHKFSKVLFTSLIIYFLLLTILFSSALIILFKKYSQLLEEKTIMKELNYTELECTKWDSLLEDKVWSCCPKDWKPFDSNCYFPSTDSVESWMESEEKCSGIGAHLVVIHSQEEQDFLPRILDTHAAYFIGLSDPGHRQWQWVDQTPYNGNATFWHEGEPSSDNEQCVIINHHENTGWGWSDSSCSDKQKLVCQVKKIYL

Target ORF information:

RefSeq Version	NM_001005891.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus C-type lectin domain family 4, member A3 (Clec4a3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001005891.1

ORF Insert Sequence:

ATGTTTTCAG AAAACATTTA TATTAACACG AACTTCAAAA ATAAATATGA CTCCTCAGAC 
ATCGACACAG ACTTTCGGCC AGATCCCCCA AAGAAGAGCA AGTCTCAGAA AAGTTGCCAC 
AAGTTCTCCA AGGTCCTCTT TACCTCACTC ATAATCTATT TCCTGCTGTT GACAATCTTA 
TTCTCCAGTG CTCTGATCAT TCTGTTTAAA AAATATTCTC AGCTTCTGGA AGAAAAAACA 
ATTATGAAGG AACTGAACTA TACTGAATTG GAGTGTACAA AATGGGATTC ACTCTTGGAA 
GACAAAGTCT GGAGCTGTTG CCCAAAGGAT TGGAAGCCAT TTGATTCCAA CTGCTACTTC 
CCTTCCACTG ACTCAGTAGA ATCTTGGATG GAGAGTGAGG AGAAGTGCTC CGGCATAGGT 
GCTCATCTGG TGGTGATCCA CAGCCAGGAA GAGCAGGATT TCCTGCCCAG GATCCTGGAT 
ACTCATGCTG CTTATTTTAT AGGACTTTCA GATCCAGGTC ATCGACAATG GCAATGGGTC 
GATCAGACAC CATACAATGG GAATGCCACA TTCTGGCATG AAGGTGAGCC CAGCAGTGAC 
AATGAACAAT GTGTTATAAT AAATCATCAT GAGAATACTG GATGGGGCTG GAGTGATAGC 
TCTTGCAGTG ATAAACAGAA GTTGGTTTGT CAGGTGAAAA AAATATACTT ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Crystal structure of human dendritic cell inhibitory receptor C-type lectin domain reveals the binding mode with N-glycan.
FEBS letters590(8)1280-8(2016 04)
Nagae M,Ikeda A,Hanashima S,Kojima T,Matsumoto N,Yamamoto K,Yamaguchi Y

Cross-priming CD8+ T cells by targeting antigens to human dendritic cells through DCIR.
Blood116(10)1685-97(2010 Sep)
Klechevsky E,Flamar AL,Cao Y,Blanck JP,Liu M,O'Bar A,Agouna-Deciat O,Klucar P,Thompson-Snipes L,Zurawski S,Reiter Y,Palucka AK,Zurawski G,Banchereau J

The rat antigen-presenting lectin-like receptor complex influences innate immunity and development of infectious diseases.
Genes and immunity10(3)227-36(2009 Apr)
Guo JP,Verdrengh M,Tarkowski A,Lange S,Jennische E,Lorentzen JC,Harris RA

Targeting DCIR on human plasmacytoid dendritic cells results in antigen presentation and inhibits IFN-alpha production.
Blood111(8)4245-53(2008 Apr)
Meyer-Wentrup F,Benitez-Ribas D,Tacken PJ,Punt CJ,Figdor CG,de Vries IJ,Adema GJ

Association of arthritis with a gene complex encoding C-type lectin-like receptors.
Arthritis and rheumatism56(8)2620-32(2007 Aug)
Lorentzen JC,Flornes L,Ekl?w C,B?ckdahl L,Ribbhammar U,Guo JP,Smolnikova M,Dissen E,Seddighzadeh M,Brookes AJ,Alfredsson L,Klareskog L,Padyukov L,Fossum S

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Clec4a3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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