Syvn1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Syvn1
Entrez Gene ID	361712
Full Name	synoviolin 1
Synonyms	RGD1310488
General protein information	Preferred Names synoviolin 1 Names E3 ubiquitin-protein ligase synoviolin HRD1 protein synovial apoptosis inhibitor 1, synoviolin
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q43

mRNA and Protein(s)

mRNA	Protein	Name
NM_001100739.1	NP_001094209.1	E3 ubiquitin-protein ligase synoviolin
XM_006230852.3	XP_006230914.1	E3 ubiquitin-protein ligase synoviolin isoform X1

Pathways from BioSystems

Homologies

Arabidopsis thaliana (thale cress)	AT1G65040	NP_849843.3
	SYVN1	XP_001114254.1
Mus musculus (house mouse)	Syvn1	NP_001158181.1
Oryza sativa (rice)	Os06g0301000	NP_001057454.1
Rattus norvegicus (Norway rat)	Syvn1	NP_001094209.1
Danio rerio (zebrafish)	syvn1	NP_997900.1
Xenopus tropicalis (tropical clawed frog)	syvn1	NP_001164301.1
Homo sapiens (human)	SYVN1	NP_757385.1
Pan troglodytes (chimpanzee)	SYVN1	XP_522059.3
Canis lupus familiaris (dog)	SYVN1	XP_005631547.1
Caenorhabditis elegans (roundworm)	sel-11	NP_505969.1
Bos taurus (cattle)	SYVN1	NP_001095369.1
Arabidopsis thaliana (thale cress)	AT3G16090	NP_188230.1

Gene Ontology
Bibliography

Related articles in PubMed

Endoplasmic Reticulum Stress Induces HRD1 to Protect Alveolar Type II Epithelial Cells from Apoptosis Induced by Cigarette Smoke Extract.
Tan SX, Jiang DX, Hu RC, Dai AG, Gan GX, Fu DY, Kong CC, Chen YR, Wang LL, Li J
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology43(4)1337-1345(2017)

Association of the SEL1L protein transmembrane domain with HRD1 ubiquitin ligase regulates ERAD-L.
Hosokawa N, Wada I
The FEBS journal283(1)157-72(2016 Jan)

Identification of ERAD components essential for dislocation of the null Hong Kong variant of ?-1-antitrypsin (NHK).
Zhong Y, Shen H, Wang Y, Yang Y, Yang P, Fang S
Biochemical and biophysical research communications458(2)424-8(2015 Mar)

Icariin induces synoviolin expression through NFE2L1 to protect neurons from ER stress-induced apoptosis.
Li F, Gao B, Dong H, Shi J, Fang D
PloS one10(3)e0119955(2015)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Endoplasmic reticulum stress induces HRD1 to protect alveolar type II epithelial cells from apoptosis induced by cigarette smoke extract.
Title: Endoplasmic Reticulum Stress Induces HRD1 to Protect Alveolar Type II Epithelial Cells from Apoptosis Induced by Cigarette Smoke Extract.

our study reveals Icariin-induced Synoviolin expression through NFE2L1 as a previously unappreciated molecular mechanism underlying the neuronal protective function of Icariin.
Title: Icariin induces synoviolin expression through NFE2L1 to protect neurons from ER stress-induced apoptosis.

The following Syvn1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Syvn1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa07656	NM_001100739.1 Latest version!	Rattus norvegicus synoviolin 1 (Syvn1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$356.30 $509.00
ORa23808	XM_006230852.3 Latest version!	Rattus norvegicus synoviolin 1 (Syvn1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Syvn1 ( NM_001100739.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001094209.1 Rattus norvegicus synoviolin 1 (Syvn1), mRNA.

Price & Availability↑

CloneID	ORa07656
Clone ID Related Accession (Same CDS sequence)	NM_001100739.1
Accession Version	NM_001100739.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1827bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-01
Organism	Rattus norvegicus(Norway rat)
Product	E3 ubiquitin-protein ligase synoviolin
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC166727.1. On or before Jun 8, 2008 this sequence version replaced XM_001074153.1, XM_341999.3, XM_001075008.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC166727.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGTTCCGCA CCGCAGTGAT GATGGCGGCC AGCCTGGCGC TGACCGGGGC AGTGGTGGCT 
CATGCCTACT ACCTCAAACA CCAGTTCTAC CCCACTGTCG TGTATTTGAC CAAATCCAGC 
CCCAGTATGG CAGTCCTGTA CATCCAGGCC TTTGTCCTTG TCTTCCTCTT GGGCAAGGTG 
ATGGGCAAGG TGTTTTTTGG GCAGCTGAGG GCAGCAGAAA TGGAGCACCT CTTGGAACGG 
TCCTGGTATG CTGTCACTGA GACTTGCTTG GCCTTCACCG TTTTTCGGGA TGACTTCAGC 
CCTCGCTTTG TGGCACTCTT TACACTCCTT CTCTTCCTCA AATGTTTCCA TTGGTTGGCT 
GAAGACCGTG TGGACTTTAT GGAACGCAGC CCCAACATCT CTTGGCTTTT CCACTGCCGC 
ATTGTCTCTC TTATGTTCCT CCTGGGCATC CTGGACTTCC TCTTTGTCAG CCACGCTTAT 
CACAGCATCC TGACCCGAGG GGCGTCTGTG CAGCTGGTGT TTGGCTTTGA GTATGCCATT 
CTGATGACCA TGGTGCTCAC CATCTTCATC AAGTATGTGC TGCACTCCGT GGACCTCCAG 
AGTGAGAATC CCTGGGACAA CAAGGCCGTG TACATGCTCT ACACGGAGCT GTTTACAGGC 
TTTATCAAGG TCCTGCTGTA CATGGCCTTT ATGACCATCA TGATCAAGGT GCACACATTT 
CCGCTCTTTG CCATTAGGCC CATGTACCTG GCCATGAGGC AGTTCAAGAA AGCTGTGACA 
GATGCCATCA TGTCTCGCAG AGCCATCCGC AACATGAACA CACTGTACCC GGATGCCACC 
CCCGAGGAGC TCCAGGCAAT GGATAACGTC TGTATCATCT GCAGAGAAGA AATGGTGACC 
GGTGCTAAGA GATTGCCTTG CAACCACATC TTTCATACGA GCTGCCTGCG CTCCTGGTTC 
CAGAGACAAC AGACCTGCCC GACATGCCGT ATGGATGTTC TGCGGGCATC ATTGCCAGCC 
CAGTCACCAC CACCCCCTGA GCCTGCTGAC CAAGGAGCCC CCCCTGCCCC TCATCCCCCA 
CCACTGCTGC CACAGCCCCC TAATTTCCCC CAGGGCCTCC TGCCTCCTTT TCCTCCGGGC 
ATGTTCCCAC TGTGGCCACC AATGGGTCCC TTTCCACCTG TCCCACCTCC CCCAAGCTCA 
GGAGAGGCTG CAGCTCCTCC GTCCACCAGT GCAGCCACTT CTCGACCCAG TGGAGCAGCC 
ACCACCACAG CTGCTGGCAC GAGTACTTCT GCCCCAGCAT CTGGCTCTGT ACCTGGCCCA 
GAGGCTGGTC CTGCCCCTGG CTTCCCTTTC CCTCCTCCTT GGATGGGTAT GCCTCTGCCT 
CCACCTTTTG CCTTCCCCCC GATGCCTGTG CCTCCTGCGG GCTTTGCTGG CCTAACCCCA 
GAGGAGCTGC GGGCACTGGA GGGCCATGAG CGGCAGCACT TGGAGGCCCG GCTACAGAGT 
CTGCGCAACA TACACACACT ACTGGACGCC GCCATGCTGC AAATCAACCA GTACCTCACT 
GTCCTGGCCT CCCTGGGCCC CCCCAGGCCA GCTACTTCAG TGAACCCCAC TGAAGAGACT 
GCCTCTACAG TGGTATCTGC TACCCCTTCC ACCAGCGTCC CCAGCTCTGA GGCTCCTGCC 
CCATCCCTGG GAGCCTCCCC ACCAATTCCT GAAGCTGAAA AGCCTCCTGT GAGCACTGCA 
GAAGAGCTTC CTGAGGATGG AGAGCCTGAT GCTGCAGAAC TCCGCCGGCG TCGCCTGCAG 
AAGCTCGAGT CTCCCGTTGC CCACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001094209.1
CDS	102..1928
Translation	MFRTAVMMAASLALTGAVVAHAYYLKHQFYPTVVYLTKSSPSMAVLYIQAFVLVFLLGKVMGKVFFGQLRAAEMEHLLERSWYAVTETCLAFTVFRDDFSPRFVALFTLLLFLKCFHWLAEDRVDFMERSPNISWLFHCRIVSLMFLLGILDFLFVSHAYHSILTRGASVQLVFGFEYAILMTMVLTIFIKYVLHSVDLQSENPWDNKAVYMLYTELFTGFIKVLLYMAFMTIMIKVHTFPLFAIRPMYLAMRQFKKAVTDAIMSRRAIRNMNTLYPDATPEELQAMDNVCIICREEMVTGAKRLPCNHIFHTSCLRSWFQRQQTCPTCRMDVLRASLPAQSPPPPEPADQGAPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPPSSGEAAAPPSTSAATSRPSGAATTTAAGTSTSAPASGSVPGPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAGFAGLTPEELRALEGHERQHLEARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPRPATSVNPTEETASTVVSATPSTSVPSSEAPAPSLGASPPIPEAEKPPVSTAEELPEDGEPDAAELRRRRLQKLESPVAH

Target ORF information:

RefSeq Version	NM_001100739.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus synoviolin 1 (Syvn1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001100739.1

ORF Insert Sequence:

ATGTTCCGCA CCGCAGTGAT GATGGCGGCC AGCCTGGCGC TGACCGGGGC AGTGGTGGCT 
CATGCCTACT ACCTCAAACA CCAGTTCTAC CCCACTGTCG TGTATTTGAC CAAATCCAGC 
CCCAGTATGG CAGTCCTGTA CATCCAGGCC TTTGTCCTTG TCTTCCTCTT GGGCAAGGTG 
ATGGGCAAGG TGTTTTTTGG GCAGCTGAGG GCAGCAGAAA TGGAGCACCT CTTGGAACGG 
TCCTGGTATG CTGTCACTGA GACTTGCTTG GCCTTCACCG TTTTTCGGGA TGACTTCAGC 
CCTCGCTTTG TGGCACTCTT TACACTCCTT CTCTTCCTCA AATGTTTCCA TTGGTTGGCT 
GAAGACCGTG TGGACTTTAT GGAACGCAGC CCCAACATCT CTTGGCTTTT CCACTGCCGC 
ATTGTCTCTC TTATGTTCCT CCTGGGCATC CTGGACTTCC TCTTTGTCAG CCACGCTTAT 
CACAGCATCC TGACCCGAGG GGCGTCTGTG CAGCTGGTGT TTGGCTTTGA GTATGCCATT 
CTGATGACCA TGGTGCTCAC CATCTTCATC AAGTATGTGC TGCACTCCGT GGACCTCCAG 
AGTGAGAATC CCTGGGACAA CAAGGCCGTG TACATGCTCT ACACGGAGCT GTTTACAGGC 
TTTATCAAGG TCCTGCTGTA CATGGCCTTT ATGACCATCA TGATCAAGGT GCACACATTT 
CCGCTCTTTG CCATTAGGCC CATGTACCTG GCCATGAGGC AGTTCAAGAA AGCTGTGACA 
GATGCCATCA TGTCTCGCAG AGCCATCCGC AACATGAACA CACTGTACCC GGATGCCACC 
CCCGAGGAGC TCCAGGCAAT GGATAACGTC TGTATCATCT GCAGAGAAGA AATGGTGACC 
GGTGCTAAGA GATTGCCTTG CAACCACATC TTTCATACGA GCTGCCTGCG CTCCTGGTTC 
CAGAGACAAC AGACCTGCCC GACATGCCGT ATGGATGTTC TGCGGGCATC ATTGCCAGCC 
CAGTCACCAC CACCCCCTGA GCCTGCTGAC CAAGGAGCCC CCCCTGCCCC TCATCCCCCA 
CCACTGCTGC CACAGCCCCC TAATTTCCCC CAGGGCCTCC TGCCTCCTTT TCCTCCGGGC 
ATGTTCCCAC TGTGGCCACC AATGGGTCCC TTTCCACCTG TCCCACCTCC CCCAAGCTCA 
GGAGAGGCTG CAGCTCCTCC GTCCACCAGT GCAGCCACTT CTCGACCCAG TGGAGCAGCC 
ACCACCACAG CTGCTGGCAC GAGTACTTCT GCCCCAGCAT CTGGCTCTGT ACCTGGCCCA 
GAGGCTGGTC CTGCCCCTGG CTTCCCTTTC CCTCCTCCTT GGATGGGTAT GCCTCTGCCT 
CCACCTTTTG CCTTCCCCCC GATGCCTGTG CCTCCTGCGG GCTTTGCTGG CCTAACCCCA 
GAGGAGCTGC GGGCACTGGA GGGCCATGAG CGGCAGCACT TGGAGGCCCG GCTACAGAGT 
CTGCGCAACA TACACACACT ACTGGACGCC GCCATGCTGC AAATCAACCA GTACCTCACT 
GTCCTGGCCT CCCTGGGCCC CCCCAGGCCA GCTACTTCAG TGAACCCCAC TGAAGAGACT 
GCCTCTACAG TGGTATCTGC TACCCCTTCC ACCAGCGTCC CCAGCTCTGA GGCTCCTGCC 
CCATCCCTGG GAGCCTCCCC ACCAATTCCT GAAGCTGAAA AGCCTCCTGT GAGCACTGCA 
GAAGAGCTTC CTGAGGATGG AGAGCCTGAT GCTGCAGAAC TCCGCCGGCG TCGCCTGCAG 
AAGCTCGAGT CTCCCGTTGC CCACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Syvn1 ( XM_006230852.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006230914.1 Rattus norvegicus synoviolin 1 (Syvn1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa23808
Clone ID Related Accession (Same CDS sequence)	XM_006230852.3
Accession Version	XM_006230852.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1839bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	E3 ubiquitin-protein ligase synoviolin isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006230852.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTCCGCA CCGCAGTGAT GATGGCGGCC AGCCTGGCGC TGACCGGGGC AGTGGTGGCT 
CATGCCTACT ACCTCAAACA CCAGTTCTAC CCCACTGTCG TGTATTTGAC CAAATCCAGC 
CCCAGTATGG CAGTCCTGTA CATCCAGGCC TTTGTCCTTG TCTTCCTCTT GGGCAAGGTG 
ATGGGCAAGG TGTTTTTTGG GCAGCTGAGG GCAGCAGAAA TGGAGCACCT CTTGGAACGG 
TCCTGGTATG CTGTCACTGA GACTTGCTTG GCCTTCACCG TTTTTCGGGA TGACTTCAGC 
CCTCGCTTTG TGGCACTCTT TACACTCCTT CTCTTCCTCA AATGTTTCCA TTGGTTGGCT 
GAAGACCGTG TGGACTTTAT GGAACGCAGC CCCAACATCT CTTGGCTTTT CCACTGCCGC 
ATTGTCTCTC TTATGTTCCT CCTGGGCATC CTGGACTTCC TCTTTGTCAG CCACGCTTAT 
CACAGCATCC TGACCCGAGG GGCGTCTGTG CAGCTGGTGT TTGGCTTTGA GTATGCCATT 
CTGATGACCA TGGTGCTCAC CATCTTCATC AAGTATGTGC TGCACTCCGT GGACCTCCAG 
AGTGAGAATC CCTGGGACAA CAAGGCCGTG TACATGCTCT ACACGGAGCT GTTTACAGGC 
TTTATCAAGG TCCTGCTGTA CATGGCCTTT ATGACCATCA TGATCAAGGT GCACACATTT 
CCGCTCTTTG CCATTAGGCC CATGTACCTG GCCATGAGGC AGTTCAAGAA AGCTGTGACA 
GATGCCATCA TGTCTCGCAG AGCCATCCGC AACATGAACA CACTGTACCC GGATGCCACC 
CCCGAGGAGC TCCAGGCAAT GGATAACGTC TGTATCATCT GCAGAGAAGA AATGGTGACC 
GGTGCTAAGA GATTGCCTTG CAACCACATC TTTCATACGA GCTGCCTGCG CTCCTGGTTC 
CAGAGACAAC AGACCTGCCC GACATGCCGT ATGGATGTTC TGCGGGCATC ATTGCCAGCC 
CAGTCACCAC CACCCCCTGA GCCTGCTGAC CAAGGAGCCC CCCCTGCCCC TCATCCCCCA 
CCACTGCTGC CACAGCCCCC TAATTTCCCC CAGGGCCTCC TGCCTCCTTT TCCTCCGGGC 
ATGTTCCCAC TGTGGCCACC AATGGGTCCC TTTCCACCTG TCCCACCTCC CCCAAGCTCA 
GGAGAGGCTG CAGCTCCTCC GTCCACCAGT GCAGCCACTT CTCGACCCAG TGGAGCAGCC 
ACCACCACAG CTGCTGGCAC GAGTACTTCT GCCCCAGCAT CTGGCTCTGT ACCTGGCCCA 
GAGGCTGGTC CTGCCCCTGG CTTCCCTTTC CCTCCTCCTT GGATGGGTAT GCCTCTGCCT 
CCACCTTTTG CCTTCCCCCC GATGCCTGTG CCTCCTGCGG GCTTTGCTGG CCTAACCCCA 
GAGGAGCTGC GGGCACTGGA GGGCCATGAG CGGCAGCACT TGGAGGCCCG GCTACAGAGT 
CTGCGCAACA TACACACACT ACTGGACGCC GCCATGCTGC AAATCAACCA GTACCTCACT 
GTCCTGGCCT CCCTGGGCCC CCCCAGGCCA GCTACTTCAG TGAACCCCAC TGAAGAGACT 
GCCTCTACAG TGGTATCTGC TACCCCTTCC ACCAGCGTCC CCAGCTCTGA GGCTCCTGCC 
CCATCCCTGG GAGCCTCCCC ACCAATTCCT GAAGCTGAAA AGCCTCCTGC TCCTGAGTCA 
GTGAGCACTG CAGAAGAGCT TCCTGAGGAT GGAGAGCCTG ATGCTGCAGA ACTCCGCCGG 
CGTCGCCTGC AGAAGCTCGA GTCTCCCGTT GCCCACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006230914.1
CDS	528..2366
Translation	MFRTAVMMAASLALTGAVVAHAYYLKHQFYPTVVYLTKSSPSMAVLYIQAFVLVFLLGKVMGKVFFGQLRAAEMEHLLERSWYAVTETCLAFTVFRDDFSPRFVALFTLLLFLKCFHWLAEDRVDFMERSPNISWLFHCRIVSLMFLLGILDFLFVSHAYHSILTRGASVQLVFGFEYAILMTMVLTIFIKYVLHSVDLQSENPWDNKAVYMLYTELFTGFIKVLLYMAFMTIMIKVHTFPLFAIRPMYLAMRQFKKAVTDAIMSRRAIRNMNTLYPDATPEELQAMDNVCIICREEMVTGAKRLPCNHIFHTSCLRSWFQRQQTCPTCRMDVLRASLPAQSPPPPEPADQGAPPAPHPPPLLPQPPNFPQGLLPPFPPGMFPLWPPMGPFPPVPPPPSSGEAAAPPSTSAATSRPSGAATTTAAGTSTSAPASGSVPGPEAGPAPGFPFPPPWMGMPLPPPFAFPPMPVPPAGFAGLTPEELRALEGHERQHLEARLQSLRNIHTLLDAAMLQINQYLTVLASLGPPRPATSVNPTEETASTVVSATPSTSVPSSEAPAPSLGASPPIPEAEKPPAPESVSTAEELPEDGEPDAAELRRRRLQKLESPVAH

Target ORF information:

RefSeq Version	XM_006230852.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus synoviolin 1 (Syvn1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006230852.3

ORF Insert Sequence:

ATGTTCCGCA CCGCAGTGAT GATGGCGGCC AGCCTGGCGC TGACCGGGGC AGTGGTGGCT 
CATGCCTACT ACCTCAAACA CCAGTTCTAC CCCACTGTCG TGTATTTGAC CAAATCCAGC 
CCCAGTATGG CAGTCCTGTA CATCCAGGCC TTTGTCCTTG TCTTCCTCTT GGGCAAGGTG 
ATGGGCAAGG TGTTTTTTGG GCAGCTGAGG GCAGCAGAAA TGGAGCACCT CTTGGAACGG 
TCCTGGTATG CTGTCACTGA GACTTGCTTG GCCTTCACCG TTTTTCGGGA TGACTTCAGC 
CCTCGCTTTG TGGCACTCTT TACACTCCTT CTCTTCCTCA AATGTTTCCA TTGGTTGGCT 
GAAGACCGTG TGGACTTTAT GGAACGCAGC CCCAACATCT CTTGGCTTTT CCACTGCCGC 
ATTGTCTCTC TTATGTTCCT CCTGGGCATC CTGGACTTCC TCTTTGTCAG CCACGCTTAT 
CACAGCATCC TGACCCGAGG GGCGTCTGTG CAGCTGGTGT TTGGCTTTGA GTATGCCATT 
CTGATGACCA TGGTGCTCAC CATCTTCATC AAGTATGTGC TGCACTCCGT GGACCTCCAG 
AGTGAGAATC CCTGGGACAA CAAGGCCGTG TACATGCTCT ACACGGAGCT GTTTACAGGC 
TTTATCAAGG TCCTGCTGTA CATGGCCTTT ATGACCATCA TGATCAAGGT GCACACATTT 
CCGCTCTTTG CCATTAGGCC CATGTACCTG GCCATGAGGC AGTTCAAGAA AGCTGTGACA 
GATGCCATCA TGTCTCGCAG AGCCATCCGC AACATGAACA CACTGTACCC GGATGCCACC 
CCCGAGGAGC TCCAGGCAAT GGATAACGTC TGTATCATCT GCAGAGAAGA AATGGTGACC 
GGTGCTAAGA GATTGCCTTG CAACCACATC TTTCATACGA GCTGCCTGCG CTCCTGGTTC 
CAGAGACAAC AGACCTGCCC GACATGCCGT ATGGATGTTC TGCGGGCATC ATTGCCAGCC 
CAGTCACCAC CACCCCCTGA GCCTGCTGAC CAAGGAGCCC CCCCTGCCCC TCATCCCCCA 
CCACTGCTGC CACAGCCCCC TAATTTCCCC CAGGGCCTCC TGCCTCCTTT TCCTCCGGGC 
ATGTTCCCAC TGTGGCCACC AATGGGTCCC TTTCCACCTG TCCCACCTCC CCCAAGCTCA 
GGAGAGGCTG CAGCTCCTCC GTCCACCAGT GCAGCCACTT CTCGACCCAG TGGAGCAGCC 
ACCACCACAG CTGCTGGCAC GAGTACTTCT GCCCCAGCAT CTGGCTCTGT ACCTGGCCCA 
GAGGCTGGTC CTGCCCCTGG CTTCCCTTTC CCTCCTCCTT GGATGGGTAT GCCTCTGCCT 
CCACCTTTTG CCTTCCCCCC GATGCCTGTG CCTCCTGCGG GCTTTGCTGG CCTAACCCCA 
GAGGAGCTGC GGGCACTGGA GGGCCATGAG CGGCAGCACT TGGAGGCCCG GCTACAGAGT 
CTGCGCAACA TACACACACT ACTGGACGCC GCCATGCTGC AAATCAACCA GTACCTCACT 
GTCCTGGCCT CCCTGGGCCC CCCCAGGCCA GCTACTTCAG TGAACCCCAC TGAAGAGACT 
GCCTCTACAG TGGTATCTGC TACCCCTTCC ACCAGCGTCC CCAGCTCTGA GGCTCCTGCC 
CCATCCCTGG GAGCCTCCCC ACCAATTCCT GAAGCTGAAA AGCCTCCTGC TCCTGAGTCA 
GTGAGCACTG CAGAAGAGCT TCCTGAGGAT GGAGAGCCTG ATGCTGCAGA ACTCCGCCGG 
CGTCGCCTGC AGAAGCTCGA GTCTCCCGTT GCCCACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Endoplasmic Reticulum Stress Induces HRD1 to Protect Alveolar Type II Epithelial Cells from Apoptosis Induced by Cigarette Smoke Extract.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology43(4)1337-1345(2017)
Tan SX,Jiang DX,Hu RC,Dai AG,Gan GX,Fu DY,Kong CC,Chen YR,Wang LL,Li J

Association of the SEL1L protein transmembrane domain with HRD1 ubiquitin ligase regulates ERAD-L.
The FEBS journal283(1)157-72(2016 Jan)
Hosokawa N,Wada I

Identification of ERAD components essential for dislocation of the null Hong Kong variant of ?-1-antitrypsin (NHK).
Biochemical and biophysical research communications458(2)424-8(2015 Mar)
Zhong Y,Shen H,Wang Y,Yang Y,Yang P,Fang S

Icariin induces synoviolin expression through NFE2L1 to protect neurons from ER stress-induced apoptosis.
PloS one10(3)e0119955(2015)
Li F,Gao B,Dong H,Shi J,Fang D